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There are 18002 results for: content related to: APOE ɛ4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of Aβ protein

  1. Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-β(42) peptide in vascular dementia

    Neuropathology and Applied Neurobiology

    Volume 32, Issue 2, April 2006, Pages: 103–118, H. Lewis, D. Beher, N. Cookson, A. Oakley, M. Piggott, C. M. Morris, E. Jaros, R. Perry, P. Ince, R. A. Kenny, C. G. Ballard, M. S. Shearman and R. N. Kalaria

    Version of Record online : 13 MAR 2006, DOI: 10.1111/j.1365-2990.2006.00696.x

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    Antibody-based approaches in Alzheimer’s research: safety, pharmacokinetics, metabolism, and analytical tools

    Journal of Neurochemistry

    Volume 104, Issue 4, February 2008, Pages: 859–874, Peter Lichtlen and M. Hasan Mohajeri

    Version of Record online : 18 AUG 2008, DOI: 10.1111/j.1471-4159.2007.05064.x

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    Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine – searching for the connections

    British Journal of Pharmacology

    Volume 167, Issue 2, September 2012, Pages: 324–352, Wojciech Danysz and Chris G Parsons

    Version of Record online : 22 AUG 2012, DOI: 10.1111/j.1476-5381.2012.02057.x

  4. You have full text access to this Open Access content
    Gene therapy in Alzheimer’s disease – potential for disease modification

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 4, April 2010, Pages: 741–757, Per Nilsson, Nobuhisa Iwata, Shin-ichi Muramatsu, Lars O. Tjernberg, Bengt Winblad and Takaomi C. Saido

    Version of Record online : 16 FEB 2010, DOI: 10.1111/j.1582-4934.2010.01038.x

  5. Conformational solution studies of the SDS micelle-bound 11-28 fragment of two Alzheimer's β-amyloid variants (E22K and A21G) using CD, NMR, and MD techniques

    Biopolymers

    Volume 87, Issue 1, September 2007, Pages: 23–39, Sylwia Rodziewicz-Motowidło, Paulina Juszczyk, Aleksandra S. Kołodziejczyk, Emilia Sikorska, Agnieszka Skwierawska, Marta Oleszczuk and Zbigniew Grzonka

    Version of Record online : 29 MAY 2007, DOI: 10.1002/bip.20768

  6. Neuropathologic analysis of hematomas evacuated from patients with spontaneous intracerebral hemorrhage

    Neuropathology

    Volume 34, Issue 3, June 2014, Pages: 253–260, Justin A. Dye, Galya Rees, Isaac Yang, Paul M. Vespa, Neil A. Martin and Harry V. Vinters

    Version of Record online : 20 DEC 2013, DOI: 10.1111/neup.12089

  7. Molecules that Target beta-Amyloid

    ChemMedChem

    Volume 2, Issue 12, December 10, 2007, Pages: 1674–1692, Cliff I. Stains, Kalyani Mondal and Indraneel Ghosh

    Version of Record online : 19 OCT 2007, DOI: 10.1002/cmdc.200700140

  8. Interaction of Aβ(25–35) fibrillation products with mitochondria: Effect of small-molecule natural products

    Peptide Science

    Volume 102, Issue 6, November 2014, Pages: 473–486, Maryam Ghobeh, Shahin Ahmadian, Ali Akbar Meratan, Azadeh Ebrahim-Habibi, Atiyeh Ghasemi, Mahshid Shafizadeh and Mohsen Nemat-Gorgani

    Version of Record online : 20 NOV 2014, DOI: 10.1002/bip.22572

  9. Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-β peptide

    Proteins: Structure, Function, and Bioinformatics

    Volume 72, Issue 1, July 2008, Pages: 1–24, Eva Y. Chi, Canay Ege, Amy Winans, Jaroslaw Majewski, Guohui Wu, Kristian Kjaer and Ka Yee C. Lee

    Version of Record online : 10 JAN 2008, DOI: 10.1002/prot.21887

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    Animal models in the drug discovery pipeline for Alzheimer's disease

    British Journal of Pharmacology

    Volume 164, Issue 4, October 2011, Pages: 1285–1300, Debby Van Dam and Peter Paul De Deyn

    Version of Record online : 26 SEP 2011, DOI: 10.1111/j.1476-5381.2011.01299.x

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    The Nonfibrillar Amyloid β-Peptide Induces Apoptotic Neuronal Cell Death

    Journal of Neurochemistry

    Volume 73, Issue 4, October 1999, Pages: 1626–1634, Thierry Pillot, Béatrice Drouet, Sophie Queillé, Christine Labeur, Joël Vandekerckhove, Maryvonne Rosseneu, Martine Pinçon-Raymond and Jean Chambaz

    Version of Record online : 17 JAN 2002, DOI: 10.1046/j.1471-4159.1999.0731626.x

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    The amyloid cascade hypothesis: are we poised for success or failure?

    Journal of Neurochemistry

    Volume 139, Issue S2, October 2016, Pages: 237–252, Eric Karran and Bart De Strooper

    Version of Record online : 3 JUN 2016, DOI: 10.1111/jnc.13632

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    Molecular Determinants of the Interaction Between the C-Terminal Domain of Alzheimer's β-Amyloid Peptide and Apolipoprotein E α-Helices

    Journal of Neurochemistry

    Volume 73, Issue 2, August 1999, Pages: 758–769, Laurence Lins, Annick Thomas-Soumarmon, Thierry Pillot, Joël Vandekerckhove, Maryvonne Rosseneu and Robert Brasseur

    Version of Record online : 18 JAN 2002, DOI: 10.1046/j.1471-4159.1999.0730758.x

  14. Time for a Change in the Research Paradigm for Alzheimer's Disease: The Value of a Chaotic Matrix Modeling Approach

    CNS Neuroscience & Therapeutics

    Volume 16, Issue 4, August 2010, Pages: 254–262, Sally Hunter, Robert P. Friedland and Carol Brayne

    Version of Record online : 11 DEC 2009, DOI: 10.1111/j.1755-5949.2009.00117.x

  15. The World of Dementia Beyond 2020

    Journal of the American Geriatrics Society

    Volume 59, Issue 5, May 2011, Pages: 923–927, Henry Brodaty, Monique M. B. Breteler, Steven T. DeKosky, Pascale Dorenlot, Laura Fratiglioni, Christoph Hock, Paul-Ariel Kenigsberg, Philip Scheltens and Bart De Strooper

    Version of Record online : 13 APR 2011, DOI: 10.1111/j.1532-5415.2011.03365.x

  16. Role of proteoglycans and glycosaminoglycans in the pathogenesis of Alzheimer's disease and related disorders: Amyloidogenesis and therapeutic strategies—A review

    Journal of Neuroscience Research

    Volume 88, Issue 11, 15 August 2010, Pages: 2303–2315, Toshio Ariga, Tadashi Miyatake and Robert K. Yu

    Version of Record online : 5 APR 2010, DOI: 10.1002/jnr.22393

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    Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014

    Journal of Internal Medicine

    Volume 275, Issue 3, March 2014, Pages: 251–283, L. S. Schneider, F. Mangialasche, N. Andreasen, H. Feldman, E. Giacobini, R. Jones, V. Mantua, P. Mecocci, L. Pani, B. Winblad and M. Kivipelto

    Version of Record online : 8 MAR 2014, DOI: 10.1111/joim.12191

  18. You have full text access to this OnlineOpen article
    Kinetic and structural characterization of amyloid-β peptide hydrolysis by human angiotensin-1-converting enzyme

    The FEBS Journal

    Volume 283, Issue 6, March 2016, Pages: 1060–1076, Kate M. Larmuth, Geoffrey Masuyer, Ross G. Douglas, Sylva L. Schwager, K. Ravi Acharya and Edward D. Sturrock

    Version of Record online : 9 FEB 2016, DOI: 10.1111/febs.13647

  19. Approaches to Amyloid Therapies for the Treatment of Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Albert J. Robichaud, Ji-In Kim and J. Steven Jacobsen

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc249

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    Emerging drug targets for Aβ and tau in Alzheimer's disease: a systematic review

    British Journal of Clinical Pharmacology

    Volume 80, Issue 2, August 2015, Pages: 221–234, Sophie West and Praveen Bhugra

    Version of Record online : 8 JUN 2015, DOI: 10.1111/bcp.12621