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There are 17222 results for: content related to: Current perspectives on BRCA1 - and BRCA2 -associated breast cancers

  1. Multiple copies of mutant BRCA1 and BRCA2 alleles in breast tumors from germ-line mutation carriers

    Genes, Chromosomes and Cancer

    Volume 28, Issue 4, August 2000, Pages: 432–442, Synnöve Staff, Nina N. Nupponen, Åke Borg, Jorma J. Isola and Minna M. Tanner

    Version of Record online : 14 JUN 2000, DOI: 10.1002/1098-2264(200008)28:4<432::AID-GCC9>3.0.CO;2-J

  2. Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice

    Genes, Chromosomes and Cancer

    Volume 36, Issue 4, April 2003, Pages: 317–331, Greg Donoho, Mark A. Brenneman, Tracy X. Cui, Dorit Donoviel, Hannes Vogel, Edwin H. Goodwin, David J. Chen and Paul Hasty

    Version of Record online : 30 JAN 2003, DOI: 10.1002/gcc.10148

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    Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

    The EMBO Journal

    Volume 20, Issue 17, September 3, 2001, Pages: 4704–4716, Andrew Tutt, David Bertwistle, Janet Valentine, Anastasia Gabriel, Sally Swift, Gillian Ross, Carol Griffin, John Thacker and Alan Ashworth

    Version of Record online : 3 SEP 2001, DOI: 10.1093/emboj/20.17.4704

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    BRCA2 is required for neurogenesis and suppression of medulloblastoma

    The EMBO Journal

    Volume 26, Issue 11, June 6, 2007, Pages: 2732–2742, Pierre-Olivier Frappart, Youngsoo Lee, Jayne Lamont and Peter J McKinnon

    Version of Record online : 3 MAY 2007, DOI: 10.1038/sj.emboj.7601703

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    Unravelling modifiers of breast and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers: update on genetic modifiers

    Journal of Internal Medicine

    Volume 271, Issue 4, April 2012, Pages: 331–343, D. R. Barnes and A. C. Antoniou

    Version of Record online : 23 MAR 2012, DOI: 10.1111/j.1365-2796.2011.02502.x

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    Secondary mutations of BRCA1/2 and drug resistance

    Cancer Science

    Volume 102, Issue 4, April 2011, Pages: 663–669, Kiranjit K. Dhillon, Elizabeth M. Swisher and Toshiyasu Taniguchi

    Version of Record online : 30 JAN 2011, DOI: 10.1111/j.1349-7006.2010.01840.x

  7. A diagnostic genetic test for the physical mapping of germline rearrangements in the susceptibility breast cancer genes BRCA1 and BRCA2

    Human Mutation

    Volume 33, Issue 6, June 2012, Pages: 998–1009, Kevin Cheeseman, Etienne Rouleau, Anne Vannier, Aurélie Thomas, Adrien Briaux, Cedrick Lefol, Pierre Walrafen, Aaron Bensimon, Rosette Lidereau, Emmanuel Conseiller and Maurizio Ceppi

    Version of Record online : 4 APR 2012, DOI: 10.1002/humu.22060

  8. Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells

    The Journal of Pathology

    Volume 234, Issue 3, November 2014, Pages: 386–397, Hong Xu, Jian Xian, Emmanuelle Vire, Steven McKinney, Vivien Wei, Jason Wong, Rebecca Tong, Tony Kouzarides, Carlos Caldas and Samuel Aparicio

    Version of Record online : 28 AUG 2014, DOI: 10.1002/path.4404

  9. Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A

    Genes, Chromosomes and Cancer

    Volume 39, Issue 3, March 2004, Pages: 236–248, Patricia A. Mote, Jennifer A. Leary, Kelly A. Avery, Kerstin Sandelin, Georgia Chenevix-Trench, Judy A. Kirk and Christine L. Clarke

    Version of Record online : 8 JAN 2004, DOI: 10.1002/gcc.10321

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    Improved survival for BRCA2-associated serous ovarian cancer compared with both BRCA-negative and BRCA1-associated serous ovarian cancer


    Volume 118, Issue 15, 1 August 2012, Pages: 3703–3709, David M. Hyman, Qin Zhou, Alexia Iasonos, Rachel N. Grisham, Angela G. Arnold, Mary F. Phillips, Jasmine Bhatia, Douglas A. Levine, Carol Aghajanian, Kenneth Offit, Richard R. Barakat, David R. Spriggs and Noah D. Kauff

    Version of Record online : 2 DEC 2011, DOI: 10.1002/cncr.26655

  11. Skin cancer risk in BRCA1/2 mutation carriers

    British Journal of Dermatology

    Volume 172, Issue 6, June 2015, Pages: 1498–1506, P.V. Gumaste, L.A. Penn, R.M. Cymerman, T. Kirchhoff, D. Polsky and B. McLellan

    Version of Record online : 29 APR 2015, DOI: 10.1111/bjd.13626

  12. You have full text access to this OnlineOpen article
    Whole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours

    The Journal of Pathology

    Volume 236, Issue 2, June 2015, Pages: 186–200, Jeffrey C Francis, Lorenzo Melchor, James Campbell, Howard Kendrick, Wenbin Wei, Javier Armisen-Garrido, Ioannis Assiotis, Lina Chen, Iwanka Kozarewa, Kerry Fenwick, Amanda Swain, Matthew J Smalley, Christopher J Lord and Alan Ashworth

    Version of Record online : 2 APR 2015, DOI: 10.1002/path.4517

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    BRCA1 and BRCA2 mutations among breast cancer patients from the Philippines

    International Journal of Cancer

    Volume 98, Issue 4, 1 April 2002, Pages: 596–603, Maria Lourdes De Leon Matsuda, Alexander Liede, Elaine Kwan, Cynthia A. Mapua, Eva Maria C. Cutiongco, Alex Tan, Åke Borg and Steven A. Narod

    Version of Record online : 30 JAN 2002, DOI: 10.1002/ijc.10194

  14. Thymic model for examining BRCA2 expression and function

    Molecular Carcinogenesis

    Volume 35, Issue 3, November 2002, Pages: 103–109, Kristina G. Flores, Kimberly A. McAllister, Paula K. Greer, Roger W. Wiseman and Laura P. Hale

    Version of Record online : 29 OCT 2002, DOI: 10.1002/mc.10081

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    Loss of heterozygosity at 13q13 and 14q32 predicts BRCA2 inactivation in luminal breast carcinomas

    International Journal of Cancer

    Volume 133, Issue 12, 15 December 2013, Pages: 2834–2842, Nicolas Pécuchet, Tatiana Popova, Elodie Manié, Carlo Lucchesi, Aude Battistella, Anne Vincent-Salomon, Virginie Caux-Moncoutier, Marc Bollet, Brigitte Sigal-Zafrani, Xavier Sastre-Garau, Dominique Stoppa-Lyonnet and Marc-Henri Stern

    Version of Record online : 10 JUL 2013, DOI: 10.1002/ijc.28315

  16. Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation

    Clinical Genetics

    Volume 76, Issue 2, August 2009, Pages: 152–160, M-W Seong, SI Cho, D-Y Noh, W Han, S-W Kim, C-M Park, H-W Park, SY Kim, JY Kim and SS Park

    Version of Record online : 28 JUL 2009, DOI: 10.1111/j.1399-0004.2009.01202.x

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    Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer


    Volume 118, Issue 2, 15 January 2012, Pages: 493–499, Zsofia K. Stadler, Erin Salo-Mullen, Sujata M. Patil, M. Catherine Pietanza, Joseph Vijai, Emmanouil Saloustros, Nichole A. L. Hansen, Noah D. Kauff, Robert C. Kurtz, David P. Kelsen, Kenneth Offit and Mark E. Robson

    Version of Record online : 19 MAY 2011, DOI: 10.1002/cncr.26191

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    Generation of iPSCs from Genetically Corrected Brca2 Hypomorphic Cells: Implications in Cell Reprogramming and Stem Cell Therapy


    Volume 32, Issue 2, February 2014, Pages: 436–446, S. Navarro, V. Moleiro, F.J. Molina-Estevez, M.L. Lozano, R. Chinchon, E. Almarza, O. Quintana-Bustamante, G. Mostoslavsky, T. Maetzig, M. Galla, N. Heinz, B. Schiedlmeier, Y. Torres, U. Modlich, E. Samper, P. Río, J.C. Segovia, A. Raya, G. Güenechea, J.C. Izpisua-Belmonte and J.A. Bueren

    Version of Record online : 13 JAN 2014, DOI: 10.1002/stem.1586

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    Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma


    Volume 98, Issue 8, 15 October 2003, Pages: 1569–1577, William D. Foulkes, Kelly Metcalfe, Wedad Hanna, Henry T. Lynch, Parviz Ghadirian, Nadine Tung, Olofunmilayo Olopade, Barbara Weber, Jane McLennan, Ivo A. Olivotto, Ping Sun, Pierre O. Chappuis, Louis R. Bégin, Jean-Sébastien Brunet and Steven A. Narod

    Version of Record online : 8 SEP 2003, DOI: 10.1002/cncr.11688

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    BRCA1 and BRCA2 germline mutations are frequently demonstrated in both high-risk pancreatic cancer screening and pancreatic cancer cohorts


    Volume 120, Issue 13, 1 July 2014, Pages: 1960–1967, Aimee L. Lucas, Laura E. Frado, Caroline Hwang, Sheila Kumar, Lauren G. Khanna, Elana J. Levinson, John A. Chabot, Wendy K. Chung and Harold Frucht

    Version of Record online : 15 APR 2014, DOI: 10.1002/cncr.28662