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There are 29474 results for: content related to: Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia

  1. Rofecoxib for osteoarthritis

    Intervention Review

    The Cochrane Library

    Sarah E Garner, Dogan Fidan, Ruth R Frankish and Lara Maxwell

    Published Online : 24 JAN 2005, DOI: 10.1002/14651858.CD005115

  2. Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model

    Clinical Pharmacology & Therapeutics

    Volume 65, Issue 3, March 1999, Pages: 336–347, Elliot W. Ehrich, Aimee Dallob, Inge De Lepeleire, Anne Van Hecken, Denis Riendeau, Weiying Yuan, Arturo Porras, Johanna Wittreich, James R. Seibold, Paul De Schepper, Donald R. Mehlisch and Barry J. Gertz

    Version of Record online : 10 MAR 1999, DOI: 10.1016/S0009-9236(99)70113-X

  3. Rofecoxib for rheumatoid arthritis

    Intervention Review

    The Cochrane Library

    Sarah E Garner, Dogan Fidan, Ruth R Frankish, Maria Judd, Tanveer Towheed, Peter Tugwell and George A Wells

    Published Online : 24 JAN 2005, DOI: 10.1002/14651858.CD003685.pub2

  4. Single dose oral rofecoxib for acute postoperative pain in adults

    Intervention Review

    The Cochrane Library

    Simon Bulley, Sheena Derry, R Andrew Moore and Henry J McQuay

    Published Online : 7 OCT 2009, DOI: 10.1002/14651858.CD004604.pub3

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    Arthritis & Rheumatism, 2001 Annual Scientific Meeting Abstracts, November 10–15, 2001, San Francisco, CA

    Arthritis & Rheumatism

    Volume 44, Issue S9, September 2001, Pages: 277–390,

    Version of Record online : 22 FEB 2002, DOI: 10.1002/1529-0131(200109)44:9+<::AID-ART427>3.0.CO;2-4

  6. Comparative Inhibitory Activity of Rofecoxib, Meloxicam, Diclofenac, Ibuprofen, and Naproxen on COX-2 versus COX-1 in Healthy Volunteers

    The Journal of Clinical Pharmacology

    Volume 40, Issue 10, October 2000, Pages: 1109–1120, Dr. Anne van Hecken, Dr. Jules I. Schwartz, Dr. Marleen Depré, Dr. Inge de Lepeleire, Ms. Aimee Dallob, Dr. Wesley Tanaka, Ms. Kathleen Wynants, Dr. Agnes Buntinx, Dr. Jef Arnout, Ms. Peggy H. Wong, Mr. David L. Ebel, Dr. Barry J. Gertz and Dr. Paul J. de Schepper

    Version of Record online : 8 MAR 2013, DOI: 10.1177/009127000004001005

  7. The effect of rofecoxib on the pharmacodynamics and pharmacokinetics of warfarin

    Clinical Pharmacology & Therapeutics

    Volume 68, Issue 6, December 2000, Pages: 626–636, Jules I. Schwartz, Kathleen J. Bugianesi, David L. Ebel, Marina De Smet, Rita Haesen, Patrick J. Larson, Amy Ko, Rene Verbesselt, Thomas L. Hunt, Robert Lins, Simone Lens, Arturo G. Porras, John Dieck, Bart Keymeulen and Barry J. Gertz

    Version of Record online : 12 DEC 2000, DOI: 10.1067/mcp.2000.112244

  8. A New Cyclooxygenase-2 Inhibitor, Rofecoxib (VIOXX®), Did Not Alter the Antiplatelet Effects of Low-Dose Aspirin in Healthy Volunteers

    The Journal of Clinical Pharmacology

    Volume 40, Issue 12, December 2000, Pages: 1509–1515, Dr. Howard E. Greenberg, Dr. Keith Gottesdiener, Ms. Martha Huntington, Ms. Peggy Wong, Ms. Pat Larson, Ms. Lynn Wildonger, Ms. Lisa Gillen, Ms. Ellen Dorval and Dr. Scott A. Waldman

    Version of Record online : 19 MAR 2013, DOI: 10.1177/009127000004001224

  9. An Evaluation of the Dose-Dependent Inhibition of CYP1A2 by Rofecoxib Using Theophylline as a CYP1A2 Probe

    The Journal of Clinical Pharmacology

    Volume 43, Issue 10, October 2003, Pages: 1082–1090, Dr. Kenneth Bachmann, Dr. Donald White, Dr. Luis Jauregui, Dr. Jules I. Schwartz, Dr. Nancy G. B. Agrawal, Mr. Ralph Mazenko, Mr. Patrick J. Larson and Dr. Arturo G. Porras

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270003257454

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    Up-regulation of COX-2 by inhibition of COX-1 in the rat: a key to NSAID-induced gastric injury

    Alimentary Pharmacology & Therapeutics

    Volume 16, Issue s2, April 2002, Pages: 90–101, A. Tanaka, H. Araki, S. Hase, Y. Komoike and K. Takeuchi

    Version of Record online : 20 APR 2002, DOI: 10.1046/j.1365-2036.16.s2.22.x

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    Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge

    British Journal of Pharmacology

    Volume 132, Issue 7, April 2001, Pages: 1565–1573, Britta Gretzer, Nenad Maricic, Michael Respondek, Rufina Schuligoi and Brigitta M Peskar

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0703955

  12. Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans

    Clinical Pharmacology & Therapeutics

    Volume 65, Issue 6, June 1999, Pages: 653–660, Jules I. Schwartz, Chi-Chung Chan, Saurabh Mukhopadhyay, Kathleen J. McBride, Terry M. Jones, Sherilyn Adcock, Carl Moritz, Jerris Hedges, Kenneth Grasing, David Dobratz, Robert A. Cohen, Michael H. Davidson, Kenneth A. Bachmann and Barry J. Gertz

    Version of Record online : 17 JUN 1999, DOI: 10.1016/S0009-9236(99)90087-5

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    The gastrointestinal safety profile of rofecoxib, a highly selective inhibitor of cyclooxygenase-2, in humans

    Alimentary Pharmacology & Therapeutics

    Volume 15, Issue 1, January 2001, Pages: 1–9, C. J. Hawkey, L. Jackson, S. E. Harper, T. J. Simon, E. Mortensen and C. R. Lines

    Version of Record online : 7 JUL 2008, DOI: 10.1046/j.1365-2036.2001.00894.x

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    Antagonism of the antithrombotic and anti-atherosclerotic actions of aspirin by rofecoxib in the cholesterol-fed rabbit

    British Journal of Pharmacology

    Volume 164, Issue 2b, September 2011, Pages: 561–569, G Kaber, B Kaiser, D Baumgärtel-Allekotte, BH Rauch, S Noßmann, KH Heim, AA Weber, N Nagy, JW Fischer and K Schrör

    Version of Record online : 28 AUG 2011, DOI: 10.1111/j.1476-5381.2011.01392.x

  15. Effect of Rofecoxib on Prednisolone and Prednisone Pharmacokinetics in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 43, Issue 2, February 2003, Pages: 187–192, Jules I. Schwartz, Saurabh Mukhopadhyay, Arturo G. Porras, Kala-Jyoti Viswanathan-Aiyer, Sherilyn Adcock, David L. Ebel and Barry J. Gertz

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270002239828

  16. NSAIDs – COX-2 Inhibitors – Risks and Benefits

    Pharmacovigilance, Second Edition

    K. Arnold Chan, S. Christopher Jones, Pages: 583–602, 2007

    Published Online : 7 FEB 2007, DOI: 10.1002/9780470059210.ch47

  17. Efficacy and Safety of Rofecoxib 12.5 mg Versus Nabumetone 1,000 mg in Patients with Osteoarthritis of the Knee: A Randomized Controlled Trial

    Journal of the American Geriatrics Society

    Volume 52, Issue 5, May 2004, Pages: 666–674, Alan J. Kivitz, Maria W. Greenwald, Stanley B. Cohen, Adam B. Polis, Daryl K. Najarian, Mary E. Dixon, Robert A. Moidel, Jerry A. Green, Herbert S. B. Baraf, Richard A. Petruschke, Alan K. Matsumoto, Gregory P. Geba, for the Protocol 085 and study investigators

    Version of Record online : 14 APR 2004, DOI: 10.1111/j.1532-5415.2004.52201.x

  18. Enhancement of dissolution rate of rofecoxib using solid dispersions with urea

    Drug Development Research

    Volume 63, Issue 4, December 2004, Pages: 181–189, Chengsheng Liu, Kashappa Goud H. Desai, Chenguang Liu and Hyun J. Park

    Version of Record online : 28 MAR 2005, DOI: 10.1002/ddr.10412

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    Enhanced inhibitive effects of combination of rofecoxib and octreotide on the growth of human gastric cancer

    International Journal of Cancer

    Volume 112, Issue 3, 10 November 2004, Pages: 470–474, Chengwei Tang, Chunlun Liu, Xuchun Zhou and Chunhui Wang

    Version of Record online : 23 JUN 2004, DOI: 10.1002/ijc.20256

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    In vitro study of tocolytic effect of rofecoxib, a specific cyclo-oxygenase 2 inhibitor. Comparison and combination with other tocolytic agents

    BJOG: An International Journal of Obstetrics & Gynaecology

    Volume 109, Issue 9, September 2002, Pages: 983–988, Muriel Doret, Georges Mellier, Mehdi Benchaib, Jean Michel Piacenza, Claude Gharib and Jean Charles Pasquier

    Version of Record online : 22 DEC 2003, DOI: 10.1111/j.1471-0528.2002.01518.x