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There are 36810 results for: content related to: Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

  1. You have full text access to this OnlineOpen article
    Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice

    EMBO reports

    Volume 17, Issue 4, April 2016, Pages: 530–551, Sumihiro Maeda, Biljana Djukic, Praveen Taneja, Gui-Qiu Yu, Iris Lo, Allyson Davis, Ryan Craft, Weikun Guo, Xin Wang, Daniel Kim, Ravikumar Ponnusamy, T Michael Gill, Eliezer Masliah and Lennart Mucke

    Version of Record online : 1 MAR 2016, DOI: 10.15252/embr.201541438

  2. The Tau/A152T mutation, a risk factor for frontotemporal-spectrum disorders, leads to NR2B receptor-mediated excitotoxicity

    EMBO reports

    Volume 17, Issue 4, April 2016, Pages: 552–569, Jochen Martin Decker, Lars Krüger, Astrid Sydow, Frank JA Dennissen, Zuzana Siskova, Eckhard Mandelkow and Eva-Maria Mandelkow

    Version of Record online : 1 MAR 2016, DOI: 10.15252/embr.201541439

  3. You have free access to this content
    Regulatable transgenic mouse models of Alzheimer disease: onset, reversibility and spreading of Tau pathology

    The FEBS Journal

    Volume 280, Issue 18, September 2013, Pages: 4371–4381, Katja Hochgräfe, Astrid Sydow and Eva-Maria Mandelkow

    Version of Record online : 22 APR 2013, DOI: 10.1111/febs.12250

  4. You have free access to this content
    The formation of tau pathological phospho-epitopes in the axon is prevented by the dephosphorylation of selective sites in primary hippocampal neurons over-expressing human tau

    Journal of Neurochemistry

    Volume 114, Issue 5, September 2010, Pages: 1353–1367, Johanne Bertrand, Patrick Sénéchal, Mathieu Zummo-Soucy, Vanessa Plouffe and Nicole Leclerc

    Version of Record online : 10 JUN 2010, DOI: 10.1111/j.1471-4159.2010.06855.x

  5. You have free access to this content
    Kinase activities increase during the development of tauopathy in htau mice

    Journal of Neurochemistry

    Volume 103, Issue 6, December 2007, Pages: 2256–2267, Ian Kelleher, Claire Garwood, Diane P. Hanger, Brian H. Anderton and Wendy Noble

    Version of Record online : 27 AUG 2007, DOI: 10.1111/j.1471-4159.2007.04930.x

  6. Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity

    The EMBO Journal

    Volume 34, Issue 24, 14 December 2015, Pages: 3028–3041, Susanne Wegmann, Eduardo A Maury, Molly J Kirk, Lubna Saqran, Allyson Roe, Sarah L DeVos, Samantha Nicholls, Zhanyun Fan, Shuko Takeda, Ozge Cagsal-Getkin, Christopher M William, Tara L Spires-Jones, Rose Pitstick, George A Carlson, Amy M Pooler and Bradley T Hyman

    Version of Record online : 4 NOV 2015, DOI: 10.15252/embj.201592748

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    A novel calcium-binding protein is associated with tau proteins in tauopathy

    Journal of Neurochemistry

    Volume 106, Issue 1, July 2008, Pages: 96–106, Irving E. Vega, Edwin E. Traverso, Yancy Ferrer-Acosta, Eduardo Matos, Migdalisel Colon, John Gonzalez, Dennis Dickson, Michael Hutton, Jada Lewis and Shu H. Yen

    Version of Record online : 13 MAR 2008, DOI: 10.1111/j.1471-4159.2008.05339.x

  8. Effects of cyclin-dependent kinase-5 activity on apoptosis and tau phosphorylation in immortalized mouse brain cortical cells

    Journal of Neuroscience Research

    Volume 76, Issue 1, 1 April 2004, Pages: 110–120, Shirley B. Shelton, Pavan Krishnamurthy and Gail V.W. Johnson

    Version of Record online : 5 MAR 2004, DOI: 10.1002/jnr.20051

  9. You have free access to this content
    Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein

    Journal of Neurochemistry

    Volume 113, Issue 4, May 2010, Pages: 895–903, Sébastien Feuillette, Laetitia Miguel, Thierry Frébourg, Dominique Campion and Magalie Lecourtois

    Version of Record online : 27 FEB 2010, DOI: 10.1111/j.1471-4159.2010.06663.x

  10. Transgenic zebrafish model of neurodegeneration

    Journal of Neuroscience Research

    Volume 70, Issue 6, 15 December 2002, Pages: 734–745, Henry G. Tomasiewicz, Denise B. Flaherty, J.P. Soria and John G. Wood

    Version of Record online : 23 SEP 2002, DOI: 10.1002/jnr.10451

  11. You have full text access to this OnlineOpen article
    Tau physiology and pathomechanisms in frontotemporal lobar degeneration

    Journal of Neurochemistry

    Liviu-Gabriel Bodea, Anne Eckert, Lars Matthias Ittner, Olivier Piguet and Jürgen Götz

    Version of Record online : 15 JUN 2016, DOI: 10.1111/jnc.13600

  12. You have free access to this content
    Phosphorylation of tau at serine 416 by Ca2+/calmodulin-dependent protein kinase II in neuronal soma in brain

    Journal of Neurochemistry

    Volume 94, Issue 5, September 2005, Pages: 1438–1447, Hideyuki Yamamoto, Yukari Hiragami, Miyuki Murayama, Koko Ishizuka, Masahiro Kawahara and Akihiko Takashima

    Version of Record online : 5 JUL 2005, DOI: 10.1111/j.1471-4159.2005.03307.x

  13. You have free access to this content
    Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin

    The EMBO Journal

    Volume 32, Issue 22, November 13, 2013, Pages: 2920–2937, Hans Zempel, Julia Luedtke, Yatender Kumar, Jacek Biernat, Hana Dawson, Eckhard Mandelkow and Eva-Maria Mandelkow

    Version of Record online : 24 SEP 2013, DOI: 10.1038/emboj.2013.207

  14. You have free access to this content
    Glucocorticoids trigger Alzheimer disease-like pathobiochemistry in rat neuronal cells expressing human tau

    Journal of Neurochemistry

    Volume 107, Issue 2, October 2008, Pages: 385–397, Ioannis Sotiropoulos, Caterina Catania, Therese Riedemann, Jonathan P. Fry, Kieran C. Breen, Theologos M. Michaelidis and Osborne F. X. Almeida

    Version of Record online : 8 AUG 2008, DOI: 10.1111/j.1471-4159.2008.05613.x

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    Conditionally inducible tau mice – designing a better mouse model of neurodegenerative diseases

    Genes, Brain and Behavior

    Volume 7, Issue s1, February 2008, Pages: 12–27, C. Janus

    Version of Record online : 3 JAN 2008, DOI: 10.1111/j.1601-183X.2007.00375.x

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    Invited review: Animal models of tauopathies and their implications for research/translation into the clinic

    Neuropathology and Applied Neurobiology

    Volume 41, Issue 1, February 2015, Pages: 59–80, Simon Dujardin, Morvane Colin and Luc Buée

    Version of Record online : 29 JAN 2015, DOI: 10.1111/nan.12200

  17. You have free access to this content
    Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation

    FEBS Letters

    Volume 579, Issue 25, October 24, 2005, Pages: 5704–5712, Taizo Taniguchi, Nobutaka Doe, Shogo Matsuyama, Yoshihisa Kitamura, Hiroshi Mori, Naoaki Saito and Chikako Tanaka

    Version of Record online : 5 OCT 2005, DOI: 10.1016/j.febslet.2005.09.047

  18. Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation

    Glia

    Volume 64, Issue 3, March 2016, Pages: 457–471, Bernardino Ossola, Chao Zhao, Alastair Compston, Stefano Pluchino, Robin J. M. Franklin and Maria Grazia Spillantini

    Version of Record online : 18 NOV 2015, DOI: 10.1002/glia.22940

  19. You have free access to this content
    Reduced Binding of Protein Phosphatase 2A to Tau Protein with Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 Mutations

    Journal of Neurochemistry

    Volume 75, Issue 5, November 2000, Pages: 2155–2162, Michel Goedert, Sivapong Satumtira, Ross Jakes, Michael J. Smith, Craig Kamibayashi, Charles L. White III and Estelle Sontag

    Version of Record online : 4 JAN 2002, DOI: 10.1046/j.1471-4159.2000.0752155.x

  20. You have free access to this content
    Tau-Induced Traffic Jams Reflect Organelles Accumulation at Points of Microtubule Polar Mismatching

    Traffic

    Volume 9, Issue 4, April 2008, Pages: 458–471, Or A. Shemesh, Hadas Erez, Irith Ginzburg and Micha E. Spira

    Version of Record online : 21 DEC 2007, DOI: 10.1111/j.1600-0854.2007.00695.x