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There are 8909 results for: content related to: T yr682 in the A β-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance

  1. You have full text access to this OnlineOpen article
    Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1110–1121, Haiyang Guo, Zhaojian Liu, Bing Xu, Huili Hu, Zhao Wei, Qiao Liu, Xiyu Zhang, Xuebin Ding, Yu Wang, Minnan Zhao, Yaoqin Gong and Changshun Shao

    Article first published online : 8 SEP 2013, DOI: 10.1111/acel.12138

  2. You have full text access to this OnlineOpen article
    Dietary restriction involves NAD+-dependent mechanisms and a shift toward oxidative metabolism

    Aging Cell

    Volume 13, Issue 6, December 2014, Pages: 1075–1085, Natalie Moroz, Juan J. Carmona, Edward Anderson, Anne C. Hart, David A. Sinclair and T. Keith Blackwell

    Article first published online : 25 SEP 2014, DOI: 10.1111/acel.12273

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    mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity

    Aging Cell

    Volume 13, Issue 5, October 2014, Pages: 869–878, Masaki Mizunuma, Elke Neumann-Haefelin, Natalie Moroz, Yujie Li and T. Keith Blackwell

    Article first published online : 9 JUL 2014, DOI: 10.1111/acel.12248

  4. You have full text access to this OnlineOpen article
    Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21

    Aging Cell

    Volume 13, Issue 5, October 2014, Pages: 817–827, Emma K. Lees, Elżbieta Król, Louise Grant, Kirsty Shearer, Cathy Wyse, Eleanor Moncur, Aleksandra S. Bykowska, Nimesh Mody, Thomas W. Gettys and Mirela Delibegovic

    Article first published online : 17 JUN 2014, DOI: 10.1111/acel.12238

  5. You have full text access to this OnlineOpen article
    Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 584–595, Rona Baron, Alicia A. Babcock, Anna Nemirovsky, Bente Finsen and Alon Monsonego

    Article first published online : 18 MAR 2014, DOI: 10.1111/acel.12210

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    Essential role for the TRF2 telomere protein in adult skin homeostasis

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 656–668, Paula Martínez, Iole Ferrara-Romeo, Juana M. Flores and Maria A. Blasco

    Article first published online : 14 APR 2014, DOI: 10.1111/acel.12221

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    TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast

    Aging Cell

    Volume 12, Issue 4, August 2013, Pages: 563–573, Charalampos Rallis, Sandra Codlin and Jürg Bähler

    Article first published online : 2 MAY 2013, DOI: 10.1111/acel.12080

  8. You have full text access to this OnlineOpen article
    A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 431–440, Mayuko Nishimura, Caroline Kumsta, Gaurav Kaushik, Soda B. Diop, Yun Ding, Jumana Bisharat-Kernizan, Hannah Catan, Anthony Cammarato, Robert S. Ross, Adam J. Engler, Rolf Bodmer, Malene Hansen and Karen Ocorr

    Article first published online : 9 JAN 2014, DOI: 10.1111/acel.12193

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    The role of lipid-related genes, aging-related processes, and environment in healthspan

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 237–246, Alexander M. Kulminski, Irina Culminskaya, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Eric Stallard, Liubov Arbeeva and Anatoli I. Yashin

    Article first published online : 18 FEB 2013, DOI: 10.1111/acel.12046

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    Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 435–445, Valentina Gambino, Giulia De Michele, Oriella Venezia, Pierluigi Migliaccio, Valentina Dall'Olio, Loris Bernard, Simone Paolo Minardi, Maria Agnese Della Fazia, Daniela Bartoli, Giuseppe Servillo, Myriam Alcalay, Lucilla Luzi, Marco Giorgio, Heidi Scrable, Pier Giuseppe Pelicci and Enrica Migliaccio

    Article first published online : 27 MAR 2013, DOI: 10.1111/acel.12060

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    Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development

    Aging Cell

    Volume 13, Issue 2, April 2014, Pages: 292–302, Tomás McKenna, Ylva Rosengardten, Nikenza Viceconte, Jean-Ha Baek, Diana Grochová and Maria Eriksson

    Article first published online : 24 JAN 2014, DOI: 10.1111/acel.12173

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    A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 641–655, Manish Chamoli, Anupama Singh, Yasir Malik and Arnab Mukhopadhyay

    Article first published online : 21 MAR 2014, DOI: 10.1111/acel.12218

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    β-amyloid context intensifies vascular smooth muscle cells induced inflammatory response and de-differentiation

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 358–369, Amélie Vromman, Nesrine Trabelsi, Clotilde Rouxel, Gilbert Béréziat, Isabelle Limon and Régis Blaise

    Article first published online : 1 APR 2013, DOI: 10.1111/acel.12056

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    Novel interactions between mitochondrial superoxide dismutases and the electron transport chain

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1132–1140, Wichit Suthammarak, Benjamin H. Somerlot, Elyce Opheim, Margaret Sedensky and Philip G. Morgan

    Article first published online : 11 SEP 2013, DOI: 10.1111/acel.12144

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    Ventriculomegaly associated with ependymal gliosis and declines in barrier integrity in the aging human and mouse brain

    Aging Cell

    Volume 13, Issue 2, April 2014, Pages: 340–350, Brett A. Shook, Jessica B. Lennington, Rebecca L. Acabchuk, Meredith Halling, Ye Sun, John Peters, Qian Wu, Amit Mahajan, Douglas W. Fellows and Joanne C. Conover

    Article first published online : 17 DEC 2013, DOI: 10.1111/acel.12184

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    Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevity

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 457–467, Jia Hu, Min Wei, Hamed Mirzaei, Federica Madia, Mario Mirisola, Camille Amparo, Shawna Chagoury, Brian Kennedy and Valter D. Longo

    Article first published online : 20 MAR 2014, DOI: 10.1111/acel.12202

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    PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1000–1011, Ni Zeng, Kai-Ting Yang, Jennifer-Ann Bayan, Lina He, Richa Aggarwal, Joseph W. Stiles, Xiaogang Hou, Vivian Medina, Danny Abad, Beth M. Palian, Ismail Al-Abdullah, Fouad Kandeel, Deborah L. Johnson and Bangyan L. Stiles

    Article first published online : 6 AUG 2013, DOI: 10.1111/acel.12132

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    Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 345–357, Connie Jackaman, Hannah G. Radley-Crabb, Zoe Soffe, Tea Shavlakadze, Miranda D. Grounds and Delia J. Nelson

    Article first published online : 27 MAR 2013, DOI: 10.1111/acel.12062

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    Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1062–1072, Sung-E Choi, Ting Fu, Sunmi Seok, Dong-Hyun Kim, Eunkyung Yu, Kwan-Woo Lee, Yup Kang, Xiaoling Li, Byron Kemper and Jongsook K. Kemper

    Article first published online : 11 AUG 2013, DOI: 10.1111/acel.12135

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    Functional characterization of human CTC1 mutations reveals novel mechanisms responsible for the pathogenesis of the telomere disease Coats plus

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1100–1109, Peili Gu and Sandy Chang

    Article first published online : 4 SEP 2013, DOI: 10.1111/acel.12139