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There are 12062 results for: content related to: Modulation of methuselah expression targeted to D rosophila insulin-producing cells extends life and enhances oxidative stress resistance

  1. You have full text access to this OnlineOpen article
    High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 446–458, Hanna Dellago, Barbara Preschitz-Kammerhofer, Lucia Terlecki-Zaniewicz, Carina Schreiner, Klaus Fortschegger, Martina W.-F. Chang, Matthias Hackl, Rossella Monteforte, Harald Kühnel, Markus Schosserer, Florian Gruber, Erwin Tschachler, Marcel Scheideler, Regina Grillari-Voglauer, Johannes Grillari and Matthias Wieser

    Article first published online : 19 APR 2013, DOI: 10.1111/acel.12069

  2. Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 184–193, Marian Beekman, Hélène Blanché, Markus Perola, Anti Hervonen, Vladyslav Bezrukov, Ewa Sikora, Friederike Flachsbart, Lene Christiansen, Anton J. M. De Craen, Tom B. L. Kirkwood, Irene Maeve Rea, Michel Poulain, Jean-Marie Robine, Silvana Valensin, Maria Antonietta Stazi, Giuseppe Passarino, Luca Deiana, Efstathios S. Gonos, Lavinia Paternoster, Thorkild I. A. Sørensen, Qihua Tan, Quinta Helmer, Erik B. van den Akker, Joris Deelen, Francesca Martella, Heather J. Cordell, Kristin L. Ayers, James W. Vaupel, Outi Törnwall, Thomas E. Johnson, Stefan Schreiber, Mark Lathrop, Axel Skytthe, Rudi G. J. Westendorp, Kaare Christensen, Jutta Gampe, Almut Nebel, Jeanine J. Houwing-Duistermaat, Pieternella Eline Slagboom and Claudio Franceschi, the GEHA consortium

    Article first published online : 6 FEB 2013, DOI: 10.1111/acel.12039

  3. Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 257–268, Edoardo Parrella, Tom Maxim, Francesca Maialetti, Lu Zhang, Junxiang Wan, Min Wei, Pinchas Cohen, Luigi Fontana and Valter D. Longo

    Article first published online : 11 MAR 2013, DOI: 10.1111/acel.12049

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    NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 11–23, Sylvie Burnouf, Alberto Martire, Maxime Derisbourg, Cyril Laurent, Karim Belarbi, Antoine Leboucher, Francisco J. Fernandez-Gomez, Laetitia Troquier, Sabiha Eddarkaoui, Marie-Eve Grosjean, Dominique Demeyer, Anne Muhr-Tailleux, Alain Buisson, Nicolas Sergeant, Malika Hamdane, Sandrine Humez, Patrizia Popoli, Luc Buée and David Blum

    Article first published online : 23 NOV 2012, DOI: 10.1111/acel.12018

  5. Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 333–344, Mansour Alsharidah, Norman R. Lazarus, Tomasz E. George, Chibeza C. Agley, Cristiana P. Velloso and Stephen D. R. Harridge

    Article first published online : 17 MAR 2013, DOI: 10.1111/acel.12051

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    Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 156–166, Joe R. Delaney, Umema Ahmed, Annie Chou, Sylvia Sim, Daniel Carr, Christopher J. Murakami, Jennifer Schleit, George L. Sutphin, Elroy H. An, Anthony Castanza, Marissa Fletcher, Sean Higgins, Monika Jelic, Shannon Klum, Brian Muller, Zhao J. Peng, Dilreet Rai, Vanessa Ros, Minnie Singh, Helen V. Wende, Brian K. Kennedy and Matt Kaeberlein

    Article first published online : 25 DEC 2012, DOI: 10.1111/acel.12032

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    Hutchinson–Gilford progeria syndrome through the lens of transcription

    Aging Cell

    Miron Prokocimer, Rachel Barkan and Yosef Gruenbaum

    Article first published online : 19 APR 2013, DOI: 10.1111/acel.12070

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    Increased dosage of Ink4/Arf protects against glucose intolerance and insulin resistance associated with aging

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 102–111, Herminia González-Navarro, Ángela Vinué, María Jesús Sanz, Mercedes Delgado, Miguel Angel Pozo, Manuel Serrano, Deborah J. Burks and Vicente Andrés

    Article first published online : 5 DEC 2012, DOI: 10.1111/acel.12023

  9. You have full text access to this OnlineOpen article
    Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 508–517, Sebastian Schmeisser, Kathrin Schmeisser, Sandra Weimer, Marco Groth, Steffen Priebe, Eugen Fazius, Doreen Kuhlow, Denis Pick, Jürgen W. Einax, Reinhard Guthke, Matthias Platzer, Kim Zarse and Michael Ristow

    Article first published online : 6 MAY 2013, DOI: 10.1111/acel.12076

  10. The role of lipid-related genes, aging-related processes, and environment in healthspan

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 237–246, Alexander M. Kulminski, Irina Culminskaya, Konstantin G. Arbeev, Svetlana V. Ukraintseva, Eric Stallard, Liubov Arbeeva and Anatoli I. Yashin

    Article first published online : 18 FEB 2013, DOI: 10.1111/acel.12046

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    Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 67–75, Jayesh S. Salvi, Janet N.Y. Chan, Christopher Pettigrew, Tony T. Liu, Jane D. Wu and Karim Mekhail

    Article first published online : 23 NOV 2012, DOI: 10.1111/acel.12020

  12. Loss of the Birt–Hogg–Dubé gene product folliculin induces longevity in a hypoxia-inducible factor–dependent manner

    Aging Cell

    Hakam Gharbi, Francesca Fabretti, Puneet Bharill, Markus M. Rinschen, Sibylle Brinkkötter, Peter Frommolt, Volker Burst, Bernhard Schermer, Thomas Benzing and Roman-Ulrich Müller

    Article first published online : 15 MAY 2013, DOI: 10.1111/acel.12081

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    TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast

    Aging Cell

    Charalampos Rallis, Sandra Codlin and Jürg Bähler

    Article first published online : 2 MAY 2013, DOI: 10.1111/acel.12080

  14. mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 370–380, Antonella Caccamo, Andrea Magrì, David X. Medina, Elena V. Wisely, Manuel F. López-Aranda, Alcino J. Silva and Salvatore Oddo

    Article first published online : 24 MAR 2013, DOI: 10.1111/acel.12057

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    Alterations in ventricular KATP channel properties during aging

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 167–176, Li Bao, Eylem Taskin, Monique Foster, Beevash Ray, Rosa Rosario, Radha Ananthakrishnan, Susan E. Howlett, Ann M. Schmidt, Ravichandran Ramasamy and William A. Coetzee

    Article first published online : 17 DEC 2012, DOI: 10.1111/acel.12033

  16. Impaired mitochondrial fatty acid oxidation and insulin resistance in aging: novel protective role of glutathione

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 415–425, Dan Nguyen, Susan L. Samson, Vasumathi T. Reddy, Erica V. Gonzalez and Rajagopal V. Sekhar

    Article first published online : 19 APR 2013, DOI: 10.1111/acel.12073

  17. Age-related loss of nitric oxide synthase in skeletal muscle causes reductions in calpain S-nitrosylation that increase myofibril degradation and sarcopenia

    Aging Cell

    Volume 11, Issue 6, December 2012, Pages: 1036–1045, Giuseppina Samengo, Anna Avik, Brian Fedor, Daniel Whittaker, Kyu H. Myung, Michelle Wehling-Henricks and James G. Tidball

    Article first published online : 4 OCT 2012, DOI: 10.1111/acel.12003

  18. Ca2+-dependent endoplasmic reticulum stress correlates with astrogliosis in oligomeric amyloid β-treated astrocytes and in a model of Alzheimer's disease

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 292–302, Elena Alberdi, Ane Wyssenbach, María Alberdi, Mª V. Sánchez-Gómez, Fabio Cavaliere, José J. Rodríguez, Alexei Verkhratsky and Carlos Matute

    Article first published online : 28 FEB 2013, DOI: 10.1111/acel.12054

  19. Deletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgene

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 177–183, Elena Beltrami, Antonella Ruggiero, Rita Busuttil, Enrica Migliaccio, Pier Giuseppe Pelicci, Jan Vijg and Marco Giorgio

    Article first published online : 10 JAN 2013, DOI: 10.1111/acel.12036

  20. β-amyloid context intensifies vascular smooth muscle cells induced inflammatory response and de-differentiation

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 358–369, Amélie Vromman, Nesrine Trabelsi, Clotilde Rouxel, Gilbert Béréziat, Isabelle Limon and Régis Blaise

    Article first published online : 1 APR 2013, DOI: 10.1111/acel.12056