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There are 20866 results for: content related to: Deletion of p66 S hc in mice increases the frequency of size-change mutations in the lac Z transgene

  1. You have full text access to this OnlineOpen article
    let-7-repressesed Shc translation delays replicative senescence

    Aging Cell

    Volume 13, Issue 1, February 2014, Pages: 185–192, Fang Xu, Lijun Pang, Xiaoyu Cai, Xinwen Liu, Shuai Yuan, Xiuqin Fan, Bin Jiang, Xiaowei Zhang, Yali Dou, Myriam Gorospe and Wengong Wang

    Version of Record online : 25 NOV 2013, DOI: 10.1111/acel.12176

  2. You have full text access to this OnlineOpen article
    P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan

    Aging Cell

    Volume 15, Issue 3, June 2016, Pages: 446–454, Marco Giorgio, Massimo Stendardo, Enrica Migliaccio and Pier Giuseppe Pelicci

    Version of Record online : 10 MAR 2016, DOI: 10.1111/acel.12448

  3. You have full text access to this OnlineOpen article
    Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 435–445, Valentina Gambino, Giulia De Michele, Oriella Venezia, Pierluigi Migliaccio, Valentina Dall'Olio, Loris Bernard, Simone Paolo Minardi, Maria Agnese Della Fazia, Daniela Bartoli, Giuseppe Servillo, Myriam Alcalay, Lucilla Luzi, Marco Giorgio, Heidi Scrable, Pier Giuseppe Pelicci and Enrica Migliaccio

    Version of Record online : 27 MAR 2013, DOI: 10.1111/acel.12060

  4. You have full text access to this Open Access content
    The p66Shc knockout mice are short lived under natural condition

    Aging Cell

    Volume 11, Issue 1, February 2012, Pages: 162–168, Marco Giorgio, Alessandra Berry, Ina Berniakovich, Inga Poletaeva, Mirella Trinei, Massimo Stendardo, Kevork Hagopian, Jon J. Ramsey, Gino Cortopassi, Enrica Migliaccio, Sarah Nötzli, Irmgard Amrein, Hans P. Lipp, Francesca Cirulli and Pier G. Pelicci

    Version of Record online : 28 DEC 2011, DOI: 10.1111/j.1474-9726.2011.00770.x

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    Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor–MAP kinase–fos signalling pathway

    The EMBO Journal

    Volume 16, Issue 4, February 15, 1997, Pages: 706–716, Enrica Migliaccio, Simonetta Mele, Anna E. Salcini, Giuliana Pelicci, Ka-Man Venus Lai, Giulio Superti-Furga, Tony Pawson, Pier Paolo Di Fiore, Luisa Lanfrancone and Pier Giuseppe Pelicci

    Version of Record online : 15 FEB 1997, DOI: 10.1093/emboj/16.4.706

  6. D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc

    Journal of Cellular Biochemistry

    Volume 113, Issue 2, February 2012, Pages: 599–610, Kozue Sakao and Shivendra V. Singh

    Version of Record online : 5 JAN 2012, DOI: 10.1002/jcb.23386

  7. Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis

    European Journal of Neuroscience

    Volume 35, Issue 4, February 2012, Pages: 562–571, Kimmy G. Su, Costanza Savino, Gail Marracci, Priya Chaudhary, Xiaolin Yu, Brooke Morris, Danielle Galipeau, Marco Giorgio, Michael Forte and Dennis Bourdette

    Version of Record online : 25 JAN 2012, DOI: 10.1111/j.1460-9568.2011.07972.x

  8. New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases

    British Journal of Pharmacology

    Fabio Di Lisa, Marco Giorgio, Peter Ferdinandy and Rainer Schulz

    Version of Record online : 14 APR 2016, DOI: 10.1111/bph.13478

  9. Elevated p66Shc is associated with intracellular redox imbalance in developmentally compromised bovine embryos

    Molecular Reproduction and Development

    Volume 80, Issue 1, January 2013, Pages: 22–34, Nathan T. Bain, Pavneesh Madan and Dean H. Betts

    Version of Record online : 26 NOV 2012, DOI: 10.1002/mrd.22128

  10. p66Shc is involved in promoting HIF-1α accumulation and cell death in hypoxic T cells

    Journal of Cellular Physiology

    Volume 211, Issue 2, May 2007, Pages: 439–447, Fabio Carraro, Annalisa Pucci, Michela Pellegrini, Pier Giuseppe Pelicci, Cosima T. Baldari and Antonella Naldini

    Version of Record online : 13 DEC 2006, DOI: 10.1002/jcp.20951

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    p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas

    International Journal of Cancer

    Volume 108, Issue 5, 20 February 2004, Pages: 672–678, Ming-Shyue Lee, Tsukasa Igawa, Siu-Ju Chen, Dana Van Bemmel, Jamie S. Lin, Fen-Fen Lin, Sonny L. Johansson, Judith K. Christman and Ming-Fong Lin

    Version of Record online : 13 NOV 2003, DOI: 10.1002/ijc.11621

  12. You have full text access to this OnlineOpen article
    Shc depletion stimulates brown fat activity in vivo and in vitro

    Aging Cell

    Volume 13, Issue 6, December 2014, Pages: 1049–1058, Alexey Tomilov, Ahmed Bettaieb, Kyoungmi Kim, Sunil Sahdeo, Natalia Tomilova, Adam Lam, Kevork Hagopian, Michelle Connell, Jennifer Fong, Douglas Rowland, Stephen Griffey, Jon Ramsey, Fawaz Haj and Gino Cortopassi

    Version of Record online : 26 SEP 2014, DOI: 10.1111/acel.12267

  13. Reduction of p66Shc suppresses oxidative damage in retinal pigmented epithelial cells and retina

    Journal of Cellular Physiology

    Volume 209, Issue 3, December 2006, Pages: 996–1005, Zhihao Wu, Brian Rogers, Shu Kachi, Sean F. Hackett, Anna Sick and Peter A. Campochiaro

    Version of Record online : 13 SEP 2006, DOI: 10.1002/jcp.20819

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    Downregulated adaptor protein p66Shc mitigates autophagy process by low nutrient and enhances apoptotic resistance in human lung adenocarcinoma A549 cells

    The FEBS Journal

    Volume 280, Issue 18, September 2013, Pages: 4522–4530, Zhichao Zheng, Jie Yang, Dan Zhao, Dan Gao, Xiaojie Yan, Zhi Yao, Zhe Liu and Zhenyi Ma

    Version of Record online : 25 JUL 2013, DOI: 10.1111/febs.12416

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    The Shc locus regulates insulin signaling and adiposity in mammals

    Aging Cell

    Volume 10, Issue 1, February 2011, Pages: 55–65, Alexey A. Tomilov, Jon J. Ramsey, Kevork Hagopian, Marco Giorgio, Kyoungmi M. Kim, Adam Lam, Enrica Migliaccio, Kent C. Lloyd, Ina Berniakovich, Tomas A. Prolla, PierGiuseppe Pelicci and Gino A. Cortopassi

    Version of Record online : 15 NOV 2010, DOI: 10.1111/j.1474-9726.2010.00641.x

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    Differential regulation of Shc adaptor proteins in skeletal muscle, spinal cord and forebrain of aged rats with sensorimotor impairment

    Aging Cell

    Volume 2, Issue 1, February 2003, Pages: 47–57, Xiaogang Jiang, Erik Edstrom, Mikael Altun and Brun Ulfhake

    Version of Record online : 28 JAN 2003, DOI: 10.1046/j.1474-9728.2003.00030.x

  17. Sustained hippocampal neurogenesis in females is amplified in P66Shc−/− mice: An animal model of healthy aging


    Volume 22, Issue 12, December 2012, Pages: 2249–2259, Alessandra Berry, Irmgard Amrein, Sarah Nötzli, Stan E. Lazic, Veronica Bellisario, Marco Giorgio, Pier Giuseppe Pelicci, Enrico Alleva, Hans-Peter Lipp and Francesca Cirulli

    Version of Record online : 18 JUN 2012, DOI: 10.1002/hipo.22042

  18. Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters

    Immunological Reviews

    Volume 232, Issue 1, November 2009, Pages: 115–134, Francesca Finetti, Maria Teresa Savino and Cosima T. Baldari

    Version of Record online : 23 OCT 2009, DOI: 10.1111/j.1600-065X.2009.00826.x

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    The interplay between p66Shc, reactive oxygen species and cancer cell metabolism

    European Journal of Clinical Investigation

    Volume 45, Issue s1, January 2015, Pages: 25–31, Magdalena Lebiedzinska-Arciszewska, Monika Oparka, Ignacio Vega-Naredo, Agnieszka Karkucinska-Wieckowska, Paolo Pinton, Jerzy Duszynski and Mariusz R. Wieckowski

    Version of Record online : 18 DEC 2014, DOI: 10.1111/eci.12364

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    Alteration of p66shc is associated with endothelial dysfunction in the abdominal aortic coarctation of rats

    FEBS Letters

    Volume 582, Issue 17, July 23, 2008, Pages: 2561–2566, Sang Ki Lee, Hyo Shin Kim, Yun Jeong Song, Hee Kyoung Joo, Ji Young Lee, Kwon Ho Lee, Eun Jung Cho, Chung-Hyun Cho, Jin Bong Park and Byeong Hwa Jeon

    Version of Record online : 25 JUN 2008, DOI: 10.1016/j.febslet.2008.06.026