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There are 69616 results for: content related to: Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

  1. You have full text access to this OnlineOpen article
    The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

    Aging Cell

    Volume 14, Issue 4, August 2015, Pages: 644–658, Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C. Gower, Husheng Ding, Nino Giorgadze, Allyson K. Palmer, Yuji Ikeno, Gene B. Hubbard, Marc Lenburg, Steven P. O'Hara, Nicholas F. LaRusso, Jordan D. Miller, Carolyn M. Roos, Grace C. Verzosa, Nathan K. LeBrasseur, Jonathan D. Wren, Joshua N. Farr, Sundeep Khosla, Michael B. Stout, Sara J. McGowan, Heike Fuhrmann-Stroissnigg, Aditi U. Gurkar, Jing Zhao, Debora Colangelo, Akaitz Dorronsoro, Yuan Yuan Ling, Amira S. Barghouthy, Diana C. Navarro, Tokio Sano, Paul D. Robbins, Laura J. Niedernhofer and James L. Kirkland

    Version of Record online : 22 APR 2015, DOI: 10.1111/acel.12344

  2. Increased polymerase I and transcript release factor (Cavin-1) expression attenuates platelet-derived growth factor receptor signalling in senescent human fibroblasts

    Clinical and Experimental Pharmacology and Physiology

    Volume 41, Issue 3, March 2014, Pages: 169–173, Qian Li, Lin Bai, Ning Liu, Miao Wang, Jun-Ping Liu, Pingsheng Liu and Yu-Sheng Cong

    Version of Record online : 18 MAR 2014, DOI: 10.1111/1440-1681.12202

  3. The mitogen-inducible gene-6 is involved in regulation of cellular senescence in normal diploid fibroblasts

    Biology of the Cell

    Volume 105, Issue 10, October 2013, Pages: 488–499, Bushan Xie, Lin Zhao, Hao Chen, Bo Jin, Zebin Mao and Zhi Yao

    Version of Record online : 24 JUL 2013, DOI: 10.1111/boc.201200052

  4. You have full text access to this Open Access content
    Protein modification and replicative senescence of WI-38 human embryonic fibroblasts

    Aging Cell

    Volume 9, Issue 2, April 2010, Pages: 252–272, Emad K. Ahmed, Adelina Rogowska-Wrzesinska, Peter Roepstorff, Anne-Laure Bulteau and Bertrand Friguet

    Version of Record online : 22 JAN 2010, DOI: 10.1111/j.1474-9726.2010.00555.x

  5. You have full text access to this Open Access content
    Senescence-associated lncRNAs: senescence-associated long noncoding RNAs

    Aging Cell

    Volume 12, Issue 5, October 2013, Pages: 890–900, Kotb Abdelmohsen, Amaresh Panda, Min-Ju Kang, Jason Xu, Roza Selimyan, Je-Hyun Yoon, Jennifer L. Martindale, Supriyo De, William H. Wood 3rd, Kevin G. Becker and Myriam Gorospe

    Version of Record online : 14 JUL 2013, DOI: 10.1111/acel.12115

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    The transcription factor Sp1 is responsible for aging-dependent altered nucleocytoplasmic trafficking

    Aging Cell

    Volume 11, Issue 6, December 2012, Pages: 1102–1109, Sung Y. Kim, Hyun T. Kang, Jeong A. Han and Sang C. Park

    Version of Record online : 19 OCT 2012, DOI: 10.1111/acel.12012

  7. You have free access to this content
    Proteasome response to interferon-γ is altered in senescent human fibroblasts

    FEBS Letters

    Volume 580, Issue 16, July 10, 2006, Pages: 3989–3994, Fiona L.L. Stratford, Niki Chondrogianni, Ioannis P. Trougakos, Efstathios S. Gonos and A. Jennifer Rivett

    Version of Record online : 21 JUN 2006, DOI: 10.1016/j.febslet.2006.06.029

  8. Cell Culture as a Model

    Standard Article

    Comprehensive Physiology

    Vincent J. Cristofalo and Robert J. Pignolo

    Published Online : 1 JAN 2011, DOI: 10.1002/cphy.cp110104

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    Analysis of expression of growth factor receptors in replicatively and oxidatively senescent human fibroblasts

    FEBS Letters

    Volume 579, Issue 28, November 21, 2005, Pages: 6388–6394, Jian-Hua Chen, Susan E. Ozanne and C. Nicholas Hales

    Version of Record online : 25 OCT 2005, DOI: 10.1016/j.febslet.2005.09.102

  10. You have full text access to this OnlineOpen article
    Caveolae control the anti-inflammatory phenotype of senescent endothelial cells

    Aging Cell

    Volume 14, Issue 1, February 2015, Pages: 102–111, Elizabeth E. Powter, Paul R. Coleman, Mai H. Tran, Angelina J. Lay, Patrick Bertolino, Robert G. Parton, Mathew A. Vadas and Jennifer R. Gamble

    Version of Record online : 19 NOV 2014, DOI: 10.1111/acel.12270

  11. Regulation of dihydrofolate reductase gene expression and E2F components in human diploid fibroblasts during growth and senescence

    Journal of Cellular Physiology

    Volume 168, Issue 3, September 1996, Pages: 580–588, Lifeng Good, Goberdhan P. Dimri, Judith Campisi and Kuang Yu Chen

    Version of Record online : 6 DEC 1998, DOI: 10.1002/(SICI)1097-4652(199609)168:3<580::AID-JCP10>3.0.CO;2-3

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    Replicative aging down-regulates the myogenic regulatory factors in human myoblasts

    Biology of the Cell

    Volume 100, Issue 3, March 2008, Pages: 189–199, Anne Bigot, Virginie Jacquemin, Florence Debacq-Chainiaux, Gillian S. Butler-Browne, Olivier Toussaint, Denis Furling and Vincent Mouly

    Version of Record online : 9 JAN 2012, DOI: 10.1042/BC20070085

  13. You have full text access to this OnlineOpen article
    AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD+ elevation

    Aging Cell

    Volume 15, Issue 3, June 2016, Pages: 416–427, Xiaojuan Han, Haoran Tai, Xiaobo Wang, Zhe Wang, Jiao Zhou, Xiawei Wei, Yi Ding, Hui Gong, Chunfen Mo, Jie Zhang, Jianqiong Qin, Yuanji Ma, Ning Huang, Rong Xiang and Hengyi Xiao

    Version of Record online : 18 FEB 2016, DOI: 10.1111/acel.12446

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    Senescence and apoptosis: dueling or complementary cell fates?

    EMBO reports

    Volume 15, Issue 11, November 2014, Pages: 1139–1153, Bennett G Childs, Darren J Baker, James L Kirkland, Judith Campisi and Jan M van Deursen

    Version of Record online : 13 OCT 2014, DOI: 10.15252/embr.201439245

  15. The helix-loop-helix protein Id-1 and a retinoblastoma protein binding mutant of SV40 T antigen synergize to reactivate DNA synthesis in senescent human fibroblasts

    Developmental Genetics

    Volume 18, Issue 2, 1996, Pages: 161–172, Eiji Hara, J. Akif Uzman, Goberdhan P. Dimri, Jan O. Nehlin, Alessandro Testori and Judith Campisi

    Version of Record online : 6 DEC 1998, DOI: 10.1002/(SICI)1520-6408(1996)18:2<161::AID-DVG9>3.0.CO;2-7

  16. Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell-based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telomerase activation therapies

    Journal of Biomedical Materials Research Part A

    Volume 103, Issue 12, December 2015, Pages: 3993–4023, Mark A. Babizhayev and Yegor E. Yegorov

    Version of Record online : 14 AUG 2015, DOI: 10.1002/jbm.a.35515

  17. Down-regulation of Receptor-mediated Endocytosis Is Reponsible for Senescence-associated Hyporesponsiveness

    Annals of the New York Academy of Sciences

    Volume 959, Issue 1, April 2002, Pages: 45–49, SANG CHUL PARK, JEONG-SOO PARK, WOONG-YANG PARK, KYOUNG-A CHO, JEONG SOO AHN and IK SOON JANG

    Version of Record online : 24 JAN 2006, DOI: 10.1111/j.1749-6632.2002.tb02081.x

  18. Origins of G1 arrest in senescent human fibroblasts

    BioEssays

    Volume 17, Issue 6, June 1995, Pages: 537–543, Gretchen H. Stein and Vjekoslav Dulić

    Version of Record online : 5 FEB 2005, DOI: 10.1002/bies.950170610

  19. Cleavage of the epidermal growth factor receptor by a membrane-bound leupeptin-sensitive protease active in nonionic detergent lysates of senescent but not young human diploid fibroblasts

    Journal of Cellular Physiology

    Volume 160, Issue 3, September 1994, Pages: 427–434, Cathleen Carlin, Dr. Paul D. Phillips, Dr. Katherine Brooks-Frederich, Barbara B. Knowles and Dr. Vincent J. Cristofalo

    Version of Record online : 4 FEB 2005, DOI: 10.1002/jcp.1041600305

  20. You have full text access to this OnlineOpen article
    Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

    Aging Cell

    Volume 15, Issue 3, June 2016, Pages: 428–435, Yi Zhu, Tamara Tchkonia, Heike Fuhrmann-Stroissnigg, Haiming M. Dai, Yuanyuan Y. Ling, Michael B. Stout, Tamar Pirtskhalava, Nino Giorgadze, Kurt O. Johnson, Cory B. Giles, Jonathan D. Wren, Laura J. Niedernhofer, Paul D. Robbins and James L. Kirkland

    Version of Record online : 18 MAR 2016, DOI: 10.1111/acel.12445