Search Results

There are 16514 results for: content related to: TORC 1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast

  1. You have full text access to this OnlineOpen article
    Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms

    Aging Cell

    Volume 14, Issue 1, February 2015, Pages: 130–138, Emily L. Goldberg, Melissa J. Romero-Aleshire, Kristin R. Renkema, Melissa S. Ventevogel, Wade M. Chew, Jennifer L. Uhrlaub, Megan J. Smithey, Kirsten H. Limesand, Gregory D. Sempowski, Heddwen L. Brooks and Janko Nikolich-Žugich

    Article first published online : 26 NOV 2014, DOI: 10.1111/acel.12280

  2. You have full text access to this OnlineOpen article
    Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 584–595, Rona Baron, Alicia A. Babcock, Anna Nemirovsky, Bente Finsen and Alon Monsonego

    Article first published online : 18 MAR 2014, DOI: 10.1111/acel.12210

  3. You have full text access to this OnlineOpen article
    Essential role for the TRF2 telomere protein in adult skin homeostasis

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 656–668, Paula Martínez, Iole Ferrara-Romeo, Juana M. Flores and Maria A. Blasco

    Article first published online : 14 APR 2014, DOI: 10.1111/acel.12221

  4. You have full text access to this OnlineOpen article
    CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase

    Aging Cell

    Amir Kumar Singh and Uttam Pati

    Article first published online : 13 MAR 2015, DOI: 10.1111/acel.12335

  5. You have full text access to this OnlineOpen article
    Aging and radiation: bad companions

    Aging Cell

    Volume 14, Issue 2, April 2015, Pages: 153–161, Laia Hernández, Mariona Terradas, Jordi Camps, Marta Martín, Laura Tusell and Anna Genescà

    Article first published online : 2 FEB 2015, DOI: 10.1111/acel.12306

  6. You have full text access to this OnlineOpen article
    Genome-wide DNA methylation changes with age in disease-free human skeletal muscle

    Aging Cell

    Volume 13, Issue 2, April 2014, Pages: 360–366, Artem Zykovich, Alan Hubbard, James M. Flynn, Mark Tarnopolsky, Mario F. Fraga, Chad Kerksick, Dan Ogborn, Lauren MacNeil, Sean D. Mooney and Simon Melov

    Article first published online : 2 DEC 2013, DOI: 10.1111/acel.12180

  7. You have full text access to this OnlineOpen article
    Optimal body weight for health and longevity: bridging basic, clinical, and population research

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 391–400, Luigi Fontana and Frank B. Hu

    Article first published online : 14 MAR 2014, DOI: 10.1111/acel.12207

  8. You have full text access to this OnlineOpen article
    A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 641–655, Manish Chamoli, Anupama Singh, Yasir Malik and Arnab Mukhopadhyay

    Article first published online : 21 MAR 2014, DOI: 10.1111/acel.12218

  9. You have full text access to this OnlineOpen article
    Ventriculomegaly associated with ependymal gliosis and declines in barrier integrity in the aging human and mouse brain

    Aging Cell

    Volume 13, Issue 2, April 2014, Pages: 340–350, Brett A. Shook, Jessica B. Lennington, Rebecca L. Acabchuk, Meredith Halling, Ye Sun, John Peters, Qian Wu, Amit Mahajan, Douglas W. Fellows and Joanne C. Conover

    Article first published online : 17 DEC 2013, DOI: 10.1111/acel.12184

  10. You have full text access to this Open Access content
    Regional differences in the morphological and functional effects of aging on cerebral basement membranes and perivascular drainage of amyloid-β from the mouse brain

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 224–236, Cheryl A. Hawkes, Maureen Gatherer, Matthew M. Sharp, Adrienne Dorr, Ho Ming Yuen, Rajesh Kalaria, Roy O. Weller and Roxana O. Carare

    Article first published online : 18 FEB 2013, DOI: 10.1111/acel.12045

  11. You have full text access to this Open Access content
    Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 257–268, Edoardo Parrella, Tom Maxim, Francesca Maialetti, Lu Zhang, Junxiang Wan, Min Wei, Pinchas Cohen, Luigi Fontana and Valter D. Longo

    Article first published online : 11 MAR 2013, DOI: 10.1111/acel.12049

  12. You have full text access to this OnlineOpen article
    Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance

    Aging Cell

    Valerio Zolla, Irina Tsoy Nizamutdinova, Brian Scharf, Cristina C. Clement, Daisuke Maejima, Tony Akl, Takashi Nagai, Paola Luciani, Jean-Christophe Leroux, Cornelia Halin, Sabriya Stukes, Sangeeta Tiwari, Arturo Casadevall, William R. Jacobs Jr, David Entenberg, David C. Zawieja, John Condeelis, David R. Fooksman, Anatoliy A. Gashev and Laura Santambrogio

    Article first published online : 15 MAY 2015, DOI: 10.1111/acel.12330

  13. You have full text access to this OnlineOpen article
    Hypoxia disrupts proteostasis in Caenorhabditis elegans

    Aging Cell

    Volume 14, Issue 1, February 2015, Pages: 92–101, Emily M. Fawcett, Jill M. Hoyt, Jenna K. Johnson and Dana L. Miller

    Article first published online : 16 DEC 2014, DOI: 10.1111/acel.12301

  14. You have full text access to this OnlineOpen article
    Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevity

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 457–467, Jia Hu, Min Wei, Hamed Mirzaei, Federica Madia, Mario Mirisola, Camille Amparo, Shawna Chagoury, Brian Kennedy and Valter D. Longo

    Article first published online : 20 MAR 2014, DOI: 10.1111/acel.12202

  15. You have full text access to this Open Access content
    PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1000–1011, Ni Zeng, Kai-Ting Yang, Jennifer-Ann Bayan, Lina He, Richa Aggarwal, Joseph W. Stiles, Xiaogang Hou, Vivian Medina, Danny Abad, Beth M. Palian, Ismail Al-Abdullah, Fouad Kandeel, Deborah L. Johnson and Bangyan L. Stiles

    Article first published online : 6 AUG 2013, DOI: 10.1111/acel.12132

  16. You have full text access to this Open Access content
    Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice

    Aging Cell

    Volume 12, Issue 5, October 2013, Pages: 772–783, Anthony J. Donato, Ashley E. Walker, Katherine A. Magerko, R. Colton Bramwell, Alex D. Black, Grant D. Henson, Brooke R. Lawson, Lisa A. Lesniewski and Douglas R. Seals

    Article first published online : 2 JUL 2013, DOI: 10.1111/acel.12103

  17. You have full text access to this OnlineOpen article
    Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism

    Aging Cell

    Volume 13, Issue 1, February 2014, Pages: 131–141, Nirinjini Naidoo, James G. Davis, Jingxu Zhu, Maya Yabumoto, Kristan Singletary, Marishka Brown, Raymond Galante, Beamon Agarwal and Joseph A. Baur

    Article first published online : 12 NOV 2013, DOI: 10.1111/acel.12158

  18. You have full text access to this Open Access content
    Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast

    Aging Cell

    Volume 12, Issue 4, August 2013, Pages: 719–727, Bari J. Ballew and Victoria Lundblad

    Article first published online : 28 JUN 2013, DOI: 10.1111/acel.12099

  19. You have full text access to this OnlineOpen article
    Relation between TLR4/NF-κB signaling pathway activation by 27-hydroxycholesterol and 4-hydroxynonenal, and atherosclerotic plaque instability

    Aging Cell

    Simona Gargiulo, Paola Gamba, Gabriella Testa, Daniela Rossin, Fiorella Biasi, Giuseppe Poli and Gabriella Leonarduzzi

    Article first published online : 10 MAR 2015, DOI: 10.1111/acel.12322

  20. You have full text access to this OnlineOpen article
    Sex-specific effects of protein and carbohydrate intake on reproduction but not lifespan in Drosophila melanogaster

    Aging Cell

    Kim Jensen, Colin McClure, Nicholas K. Priest and John Hunt

    Article first published online : 23 MAR 2015, DOI: 10.1111/acel.12333