Search Results

There are 9830 results for: content related to: The human Δ N p53 isoform triggers metabolic and gene expression changes that activate m TOR and alter mitochondrial function

  1. You have full text access to this OnlineOpen article
    A novel kinase regulates dietary restriction-mediated longevity in Caenorhabditis elegans

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 641–655, Manish Chamoli, Anupama Singh, Yasir Malik and Arnab Mukhopadhyay

    Article first published online : 21 MAR 2014, DOI: 10.1111/acel.12218

  2. You have full text access to this Open Access content
    Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice

    Aging Cell

    Volume 12, Issue 5, October 2013, Pages: 772–783, Anthony J. Donato, Ashley E. Walker, Katherine A. Magerko, R. Colton Bramwell, Alex D. Black, Grant D. Henson, Brooke R. Lawson, Lisa A. Lesniewski and Douglas R. Seals

    Article first published online : 2 JUL 2013, DOI: 10.1111/acel.12103

  3. You have full text access to this OnlineOpen article
    Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging

    Aging Cell

    Volume 13, Issue 6, December 2014, Pages: 981–1000, Oge Arum, Ravneet K. Boparai, Jamal K. Saleh, Feiya Wang, Angela L. Dirks, Jeremy G. Turner, John J. Kopchick, Jun-Li Liu, Romesh K. Khardori and Andrzej Bartke

    Article first published online : 20 SEP 2014, DOI: 10.1111/acel.12262

  4. You have full text access to this OnlineOpen article
    Dietary restriction involves NAD+-dependent mechanisms and a shift toward oxidative metabolism

    Aging Cell

    Volume 13, Issue 6, December 2014, Pages: 1075–1085, Natalie Moroz, Juan J. Carmona, Edward Anderson, Anne C. Hart, David A. Sinclair and T. Keith Blackwell

    Article first published online : 25 SEP 2014, DOI: 10.1111/acel.12273

  5. You have full text access to this OnlineOpen article
    Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

    Aging Cell

    Talibah U. Metcalf, Rafael A. Cubas, Khader Ghneim, Michael J. Cartwright, Julien Van Grevenynghe, Justin M. Richner, David P. Olagnier, Peter A. Wilkinson, Mark J. Cameron, Byung S. Park, John B. Hiscott, Michael S. Diamond, Anne M. Wertheimer, Janko Nikolich-Zugich and Elias K. Haddad

    Article first published online : 27 FEB 2015, DOI: 10.1111/acel.12320

  6. You have full text access to this OnlineOpen article
    FSH regulates fat accumulation and redistribution in aging through the Gαi/Ca2+/CREB pathway

    Aging Cell

    Xin-Mei Liu, Hsiao Chang Chan, Guo-Lian Ding, Jie Cai, Yang Song, Ting-Ting Wang, Dan Zhang, Hui Chen, Mei Kuen Yu, Yan-Ting Wu, Fan Qu, Ye Liu, Yong-Chao Lu, Eli Y. Adashi, Jian-Zhong Sheng and He-Feng Huang

    Article first published online : 6 MAR 2015, DOI: 10.1111/acel.12331

  7. You have full text access to this OnlineOpen article
    In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells

    Aging Cell

    Michelle Ratliff, Sarah Alter, Kelly McAvoy, Daniela Frasca, Jacqueline A. Wright, Sandra S. Zinkel, Wasif N. Khan, Bonnie B. Blomberg and Richard L. Riley

    Article first published online : 27 FEB 2015, DOI: 10.1111/acel.12302

  8. You have full text access to this OnlineOpen article
    Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 584–595, Rona Baron, Alicia A. Babcock, Anna Nemirovsky, Bente Finsen and Alon Monsonego

    Article first published online : 18 MAR 2014, DOI: 10.1111/acel.12210

  9. You have full text access to this OnlineOpen article
    Essential role for the TRF2 telomere protein in adult skin homeostasis

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 656–668, Paula Martínez, Iole Ferrara-Romeo, Juana M. Flores and Maria A. Blasco

    Article first published online : 14 APR 2014, DOI: 10.1111/acel.12221

  10. You have full text access to this OnlineOpen article
    Gene expression defines natural changes in mammalian lifespan

    Aging Cell

    Alexey A. Fushan, Anton A. Turanov, Sang-Goo Lee, Eun Bae Kim, Alexei V. Lobanov, Sun Hee Yim, Rochelle Buffenstein, Sang-Rae Lee, Kyu-Tae Chang, Hwanseok Rhee, Jong-So Kim, Kap-Seok Yang and Vadim N. Gladyshev

    Article first published online : 9 FEB 2015, DOI: 10.1111/acel.12283

  11. You have full text access to this OnlineOpen article
    Modulated expression of human peripheral blood microRNAs from infancy to adulthood and its role in aging

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 679–689, Chi-Yu Lai, Yen-Tzu Wu, Sung-Liang Yu, Ya-Hui Yu, Su-Yin Lee, Chih-Min Liu, Wu-Shiun Hsieh, Hai-Gwo Hwu, Pau-Chung Chen, Suh-Fang Jeng and Wei J. Chen

    Article first published online : 6 MAY 2014, DOI: 10.1111/acel.12225

  12. You have full text access to this Open Access content
    Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 966–977, Chad Lerner, Alessandro Bitto, Daniel Pulliam, Timothy Nacarelli, Mina Konigsberg, Holly Van Remmen, Claudio Torres and Christian Sell

    Article first published online : 30 JUL 2013, DOI: 10.1111/acel.12122

  13. You have full text access to this Open Access content
    The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age-associated inflammation and oxidative stress in healthy rats

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1041–1049, Yucun Niu, Lixin Na, Rennan Feng, Liya Gong, Yue Zhao, Qiang Li, Ying Li and Changhao Sun

    Article first published online : 20 AUG 2013, DOI: 10.1111/acel.12133

  14. You have full text access to this OnlineOpen article
    Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 148–155, Henri S. Tapp, Daniel M. Commane, D. Michael Bradburn, Ramesh Arasaradnam, John C. Mathers, Ian T. Johnson and Nigel J. Belshaw

    Article first published online : 6 DEC 2012, DOI: 10.1111/acel.12030

  15. You have full text access to this Open Access content
    Novel interactions between mitochondrial superoxide dismutases and the electron transport chain

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1132–1140, Wichit Suthammarak, Benjamin H. Somerlot, Elyce Opheim, Margaret Sedensky and Philip G. Morgan

    Article first published online : 11 SEP 2013, DOI: 10.1111/acel.12144

  16. You have full text access to this OnlineOpen article
    Gene profiling reveals association between altered Wnt signaling and loss of T-cell potential with age in human hematopoietic stem cells

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 744–754, Melissa L. M. Khoo, Stephen M. Carlin, Mark A. Lutherborrow, Vivek Jayaswal, David D. F. Ma and John J. Moore

    Article first published online : 30 MAY 2014, DOI: 10.1111/acel.12229

  17. You have full text access to this OnlineOpen article
    H3K4 demethylase activities repress proliferative and postmitotic aging

    Aging Cell

    Volume 13, Issue 2, April 2014, Pages: 245–253, Stacy M. Alvares, Gaea A. Mayberry, Ebony Y. Joyner, Bernard Lakowski and Shawn Ahmed

    Article first published online : 19 NOV 2013, DOI: 10.1111/acel.12166

  18. You have full text access to this Open Access content
    Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease

    Aging Cell

    Volume 13, Issue 1, February 2014, Pages: 49–59, Joe Atherton, Ksenia Kurbatskaya, Marie Bondulich, Cara L. Croft, Claire J. Garwood, Resham Chhabra, Selina Wray, Andreas Jeromin, Diane P. Hanger and Wendy Noble

    Article first published online : 18 SEP 2013, DOI: 10.1111/acel.12148

  19. You have full text access to this Open Access content
    Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 499–507, Anita Stargardt, Judith Gillis, Willem Kamphuis, Anne Wiemhoefer, Lieneke Kooijman, Marcel Raspe, Willemien Benckhuijsen, Jan W. Drijfhout, Elly M. Hol and Eric Reits

    Article first published online : 23 APR 2013, DOI: 10.1111/acel.12074

  20. You have full text access to this OnlineOpen article
    Reductions in serum IGF-1 during aging impair health span

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 408–418, Zhenwei Gong, Oran Kennedy, Hui Sun, YingJie Wu, Garry A Williams, Laura Klein, Luis Cardoso, Ronald W. Matheny Jr, Gene B. Hubbard, Yuji Ikeno, Roger P. Farrar, Mitchell B Schaffler, Martin L Adamo, Radhika H Muzumdar and Shoshana Yakar

    Article first published online : 30 DEC 2013, DOI: 10.1111/acel.12188