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There are 19090 results for: content related to: Longevity effect of IGF -1 R +/− mutation depends on genetic background-specific receptor activation

  1. You have full text access to this OnlineOpen article
    Suppression of IGF-I signals in neural stem cells enhances neurogenesis and olfactory function during aging

    Aging Cell

    Volume 14, Issue 5, October 2015, Pages: 847–856, Zayna Chaker, Saba Aïd, Hugues Berry and Martin Holzenberger

    Version of Record online : 29 JUL 2015, DOI: 10.1111/acel.12365

  2. You have full text access to this OnlineOpen article
    Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-223 expressions: a study on postmenopausal monozygotic twin pairs

    Aging Cell

    Volume 13, Issue 5, October 2014, Pages: 850–861, Fabiola Olivieri, Maarit Ahtiainen, Raffaella Lazzarini, Eija Pöllänen, Miriam Capri, Maria Lorenzi, Gianluca Fulgenzi, Maria C. Albertini, Stefano Salvioli, Markku J. Alen, Urho M. Kujala, Giulia Borghetti, Lucia Babini, Jaakko Kaprio, Sarianna Sipilä, Claudio Franceschi, Vuokko Kovanen and Antonio D. Procopio

    Version of Record online : 18 JUL 2014, DOI: 10.1111/acel.12245

  3. PTEN regulates IGF-1R-mediated therapy resistance in melanoma

    Pigment Cell & Melanoma Research

    Volume 28, Issue 5, September 2015, Pages: 572–589, Jun Wang, Tobias Sinnberg, Heike Niessner, Rebecca Dölker, Birgit Sauer, Wolfgang E. Kempf, Friedegund Meier, Nick Leslie and Birgit Schittek

    Version of Record online : 16 AUG 2015, DOI: 10.1111/pcmr.12390

  4. Insulin-like growth factor-1 receptor is associated with better prognosis in classical Hodgkin's lymphoma: Correlation with MET expression

    International Journal of Experimental Pathology

    Volume 96, Issue 4, August 2015, Pages: 232–239, Young Wha Koh, Dok Hyun Yoon, Cheolwon Suh, Hee Jeong Cha and Jooryung Huh

    Version of Record online : 27 APR 2015, DOI: 10.1111/iep.12128

  5. You have free access to this content
    Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation

    The EMBO Journal

    Volume 27, Issue 15, August 6, 2008, Pages: 2091–2101, Heike Stachelscheid, Hady Ibrahim, Linda Koch, Annika Schmitz, Michael Tscharntke, F Thomas Wunderlich, Jeanie Scott, Christian Michels, Claudia Wickenhauser, Ingo Haase, Jens C Brüning and Carien M Niessen

    Version of Record online : 24 JUL 2008, DOI: 10.1038/emboj.2008.141

  6. You have full text access to this OnlineOpen article
    IGF-1 receptor is down-regulated by sunitinib induces MDM2-dependent ubiquitination

    FEBS Open Bio

    Volume 2, Issue 1, January 01, 2012, Pages: 1–6, Hongchang Shen, Yan Fang, Wei Dong, Xueru Mu, Qi Liu and Jiajun Du

    Version of Record online : 27 DEC 2011, DOI: 10.1016/j.fob.2011.12.001

  7. You have full text access to this Open Access content
    Heterogeneity of neuroblastoma cell lines in insulin-like growth factor 1 receptor/Akt pathway-mediated cell proliferative responses

    Cancer Science

    Volume 104, Issue 9, September 2013, Pages: 1162–1171, Lei Qi, Hidemi Toyoda, Vipin Shankar, Naoto Sakurai, Keishirou Amano, Kentaro Kihira, Tadashi Iwasa, Takao Deguchi, Hiroki Hori, Eiichi Azuma, Esteban C. Gabazza and Yoshihiro Komada

    Version of Record online : 25 JUN 2013, DOI: 10.1111/cas.12204

  8. You have free access to this content
    Epidermal growth factor receptor and insulinlike growth factor 1 receptor expression predict poor survival in pancreatic ductal adenocarcinoma


    Volume 118, Issue 14, 15 July 2012, Pages: 3484–3493, Matias E. Valsecchi, Mary McDonald, Jonathan R. Brody, Terry Hyslop, Boris Freydin, Charles J. Yeo, Charalambos Solomides, Stephen C. Peiper and Agnieszka K. Witkiewicz

    Version of Record online : 15 NOV 2011, DOI: 10.1002/cncr.26661

  9. You have free access to this content
    Molecular mechanisms involved in activity of h7C10, a humanized monoclonal antibody, to IGF-1 receptor

    International Journal of Cancer

    Volume 124, Issue 10, 15 May 2009, Pages: 2281–2293, Matthieu Broussas, Joëlle Dupont, Alexandra Gonzalez, Aline Blaecke, Mathilde Fournier, Nathalie Corvaïa and Liliane Goetsch

    Version of Record online : 26 NOV 2008, DOI: 10.1002/ijc.24186

  10. Metabotropic glutamate receptor 1 mediates melanocyte transformation via transactivation of insulin-like growth factor 1 receptor

    Pigment Cell & Melanoma Research

    Volume 27, Issue 4, July 2014, Pages: 621–629, Jessica L. F. Teh, Raj Shah, Seung-Shick Shin, Yu Wen, Janice M. Mehnert, James Goydos and Suzie Chen

    Version of Record online : 11 APR 2014, DOI: 10.1111/pcmr.12237

  11. Genetic Blockade of the Insulin-Like Growth Factor 1 Receptor for Human Malignancy

    Biology of IGF-1: Its Interaction with Insulin in Health and Malignant States: Novartis Foundation Symposium 262

    Yasushi Adachi, Choon-Taek Lee, David P. Carbone, Pages: 177–192, 2008

    Published Online : 7 OCT 2008, DOI: 10.1002/0470869976.ch11

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    Serial analysis of resected prostate cancer suggests up-regulation of type 1 IGF receptor with disease progression

    BJU International

    Volume 107, Issue 9, May 2011, Pages: 1488–1499, Benjamin W. Turney, Gareth D.H. Turner, Simon F. Brewster and Valentine M. Macaulay

    Version of Record online : 14 SEP 2010, DOI: 10.1111/j.1464-410X.2010.09556.x

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    Prognostic impact of insulin receptor expression on survival of patients with nonsmall cell lung cancer


    Volume 118, Issue 9, 1 May 2012, Pages: 2454–2465, Jin-Soo Kim, Edward S. Kim, Diane Liu, J. Jack Lee, Luisa Solis, Carmen Behrens, Scott M. Lippman, Waun Ki Hong, Ignacio I. Wistuba and Ho-Young Lee

    Version of Record online : 22 SEP 2011, DOI: 10.1002/cncr.26492

  14. Gemcitabine-(5’-phosphoramidate)-[anti-IGF-1R]: Molecular Design, Synthetic Organic Chemistry Reactions, and Antineoplastic Cytotoxic Potency in Populations of Pulmonary Adenocarcinoma (A549)

    Chemical Biology & Drug Design

    Accepted manuscript online: 25 AUG 2016, C.P. Coyne and Lakshmi Narayanan

    DOI: 10.1111/cbdd.12845

  15. You have full text access to this OnlineOpen article
    Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline

    Aging Cell

    Volume 15, Issue 1, February 2016, Pages: 181–186, Derek M. Huffman, Gabriela Farias Quipildor, Kai Mao, Xueying Zhang, Junxiang Wan, Pasha Apontes, Pinchas Cohen and Nir Barzilai

    Version of Record online : 4 NOV 2015, DOI: 10.1111/acel.12415

  16. You have full text access to this OnlineOpen article
    Interventions to Slow Aging in Humans: Are We Ready?

    Aging Cell

    Volume 14, Issue 4, August 2015, Pages: 497–510, Valter D. Longo, Adam Antebi, Andrzej Bartke, Nir Barzilai, Holly M. Brown-Borg, Calogero Caruso, Tyler J. Curiel, Rafael de Cabo, Claudio Franceschi, David Gems, Donald K. Ingram, Thomas E. Johnson, Brian K. Kennedy, Cynthia Kenyon, Samuel Klein, John J. Kopchick, Guenter Lepperdinger, Frank Madeo, Mario G. Mirisola, James R. Mitchell, Giuseppe Passarino, Karl L. Rudolph, John M. Sedivy, Gerald S. Shadel, David A. Sinclair, Stephen R. Spindler, Yousin Suh, Jan Vijg, Manlio Vinciguerra and Luigi Fontana

    Version of Record online : 22 APR 2015, DOI: 10.1111/acel.12338

  17. You have full text access to this OnlineOpen article
    Receptor tyrosine kinase profiles and human papillomavirus status in oropharyngeal squamous cell carcinoma

    Journal of Oral Pathology & Medicine

    Volume 44, Issue 9, October 2015, Pages: 734–745, Barbara Cortelazzi, Paolo Verderio, Chiara Maura Ciniselli, Sara Pizzamiglio, Paolo Bossi, Annunziata Gloghini, Ambra V. Gualeni, Chiara C. Volpi, Laura Locati, Marco A. Pierotti, Lisa Licitra, Silvana Pilotti and Federica Perrone

    Version of Record online : 14 DEC 2014, DOI: 10.1111/jop.12301

  18. You have full text access to this OnlineOpen article
    Inhibition of EGFR or IGF-1R signaling enhances radiation response in head and neck cancer models but concurrent inhibition has no added benefit

    Cancer Medicine

    Volume 4, Issue 1, January 2015, Pages: 65–74, Uma Raju, David P. Molkentine, David R. Valdecanas, Amit Deorukhkar, Kathryn A. Mason, Thomas A. Buchholz, Raymond E. Meyn, Kie-Kian Ang and Heath Skinner

    Version of Record online : 29 OCT 2014, DOI: 10.1002/cam4.345

  19. Neuroendocrine-derived peptides promote prostate cancer cell survival through activation of IGF-1R signaling

    The Prostate

    Volume 73, Issue 8, June 2013, Pages: 801–812, John O. DaSilva, George P. Amorino, Eli V. Casarez, Bradley Pemberton and Sarah J. Parsons

    Version of Record online : 28 NOV 2012, DOI: 10.1002/pros.22624

  20. Absence or low IGF-1R-expression in esophageal adenocarcinoma is associated with tumor invasiveness and radicality of surgical resection

    Journal of Surgical Oncology

    Volume 111, Issue 8, June 15, 2015, Pages: 1047–1053, Kirstin De Bruijn, Katharina Biermann, Joel Shapiro, Fadime Dogan, Manon Spaander, Joseph Janssen, Bas Wijnhoven, Gerard Borsboom, Leo Hofland and Casper van Eijck

    Version of Record online : 16 JUN 2015, DOI: 10.1002/jso.23923