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There are 11063 results for: content related to: Micro RNA -7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts

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    NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 11–23, Sylvie Burnouf, Alberto Martire, Maxime Derisbourg, Cyril Laurent, Karim Belarbi, Antoine Leboucher, Francisco J. Fernandez-Gomez, Laetitia Troquier, Sabiha Eddarkaoui, Marie-Eve Grosjean, Dominique Demeyer, Anne Muhr-Tailleux, Alain Buisson, Nicolas Sergeant, Malika Hamdane, Sandrine Humez, Patrizia Popoli, Luc Buée and David Blum

    Article first published online : 23 NOV 2012, DOI: 10.1111/acel.12018

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    High levels of oncomiR-21 contribute to the senescence-induced growth arrest in normal human cells and its knock-down increases the replicative lifespan

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 446–458, Hanna Dellago, Barbara Preschitz-Kammerhofer, Lucia Terlecki-Zaniewicz, Carina Schreiner, Klaus Fortschegger, Martina W.-F. Chang, Matthias Hackl, Rossella Monteforte, Harald Kühnel, Markus Schosserer, Florian Gruber, Erwin Tschachler, Marcel Scheideler, Regina Grillari-Voglauer, Johannes Grillari and Matthias Wieser

    Article first published online : 19 APR 2013, DOI: 10.1111/acel.12069

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    Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice

    Aging Cell

    Volume 12, Issue 5, October 2013, Pages: 772–783, Anthony J. Donato, Ashley E. Walker, Katherine A. Magerko, R. Colton Bramwell, Alex D. Black, Grant D. Henson, Brooke R. Lawson, Lisa A. Lesniewski and Douglas R. Seals

    Article first published online : 2 JUL 2013, DOI: 10.1111/acel.12103

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    Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging

    Aging Cell

    Volume 12, Issue 3, June 2013, Pages: 435–445, Valentina Gambino, Giulia De Michele, Oriella Venezia, Pierluigi Migliaccio, Valentina Dall'Olio, Loris Bernard, Simone Paolo Minardi, Maria Agnese Della Fazia, Daniela Bartoli, Giuseppe Servillo, Myriam Alcalay, Lucilla Luzi, Marco Giorgio, Heidi Scrable, Pier Giuseppe Pelicci and Enrica Migliaccio

    Article first published online : 27 MAR 2013, DOI: 10.1111/acel.12060

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    Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging

    Aging Cell

    Volume 14, Issue 2, April 2015, Pages: 249–264, Jaime L. Schneider, Joan Villarroya, Antonio Diaz-Carretero, Bindi Patel, Aleksandra M. Urbanska, Mia M. Thi, Francesc Villarroya, Laura Santambrogio and Ana Maria Cuervo

    Article first published online : 23 JAN 2015, DOI: 10.1111/acel.12310

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    Ventriculomegaly associated with ependymal gliosis and declines in barrier integrity in the aging human and mouse brain

    Aging Cell

    Volume 13, Issue 2, April 2014, Pages: 340–350, Brett A. Shook, Jessica B. Lennington, Rebecca L. Acabchuk, Meredith Halling, Ye Sun, John Peters, Qian Wu, Amit Mahajan, Douglas W. Fellows and Joanne C. Conover

    Article first published online : 17 DEC 2013, DOI: 10.1111/acel.12184

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    PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1000–1011, Ni Zeng, Kai-Ting Yang, Jennifer-Ann Bayan, Lina He, Richa Aggarwal, Joseph W. Stiles, Xiaogang Hou, Vivian Medina, Danny Abad, Beth M. Palian, Ismail Al-Abdullah, Fouad Kandeel, Deborah L. Johnson and Bangyan L. Stiles

    Article first published online : 6 AUG 2013, DOI: 10.1111/acel.12132

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    A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 431–440, Mayuko Nishimura, Caroline Kumsta, Gaurav Kaushik, Soda B. Diop, Yun Ding, Jumana Bisharat-Kernizan, Hannah Catan, Anthony Cammarato, Robert S. Ross, Adam J. Engler, Rolf Bodmer, Malene Hansen and Karen Ocorr

    Article first published online : 9 JAN 2014, DOI: 10.1111/acel.12193

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    Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-223 expressions: a study on postmenopausal monozygotic twin pairs

    Aging Cell

    Volume 13, Issue 5, October 2014, Pages: 850–861, Fabiola Olivieri, Maarit Ahtiainen, Raffaella Lazzarini, Eija Pöllänen, Miriam Capri, Maria Lorenzi, Gianluca Fulgenzi, Maria C. Albertini, Stefano Salvioli, Markku J. Alen, Urho M. Kujala, Giulia Borghetti, Lucia Babini, Jaakko Kaprio, Sarianna Sipilä, Claudio Franceschi, Vuokko Kovanen and Antonio D. Procopio

    Article first published online : 18 JUL 2014, DOI: 10.1111/acel.12245

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    Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging

    Aging Cell

    Volume 13, Issue 6, December 2014, Pages: 981–1000, Oge Arum, Ravneet K. Boparai, Jamal K. Saleh, Feiya Wang, Angela L. Dirks, Jeremy G. Turner, John J. Kopchick, Jun-Li Liu, Romesh K. Khardori and Andrzej Bartke

    Article first published online : 20 SEP 2014, DOI: 10.1111/acel.12262

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    Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevity

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 457–467, Jia Hu, Min Wei, Hamed Mirzaei, Federica Madia, Mario Mirisola, Camille Amparo, Shawna Chagoury, Brian Kennedy and Valter D. Longo

    Article first published online : 20 MAR 2014, DOI: 10.1111/acel.12202

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    Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1062–1072, Sung-E Choi, Ting Fu, Sunmi Seok, Dong-Hyun Kim, Eunkyung Yu, Kwan-Woo Lee, Yup Kang, Xiaoling Li, Byron Kemper and Jongsook K. Kemper

    Article first published online : 11 AUG 2013, DOI: 10.1111/acel.12135

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    Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging

    Aging Cell

    Volume 12, Issue 1, February 2013, Pages: 156–166, Joe R. Delaney, Umema Ahmed, Annie Chou, Sylvia Sim, Daniel Carr, Christopher J. Murakami, Jennifer Schleit, George L. Sutphin, Elroy H. An, Anthony Castanza, Marissa Fletcher, Sean Higgins, Monika Jelic, Shannon Klum, Brian Muller, Zhao J. Peng, Dilreet Rai, Vanessa Ros, Minnie Singh, Helen V. Wende, Brian K. Kennedy and Matt Kaeberlein

    Article first published online : 25 DEC 2012, DOI: 10.1111/acel.12032

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    Bmi-1 plays a critical role in protection from renal tubulointerstitial injury by maintaining redox balance

    Aging Cell

    Volume 13, Issue 5, October 2014, Pages: 797–809, Jianliang Jin, Xianhui Lv, Lulu Chen, Wei Zhang, Jinbo Li, Qian Wang, Rong Wang, Xiang Lu and Dengshun Miao

    Article first published online : 11 JUN 2014, DOI: 10.1111/acel.12236

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    Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 257–268, Edoardo Parrella, Tom Maxim, Francesca Maialetti, Lu Zhang, Junxiang Wan, Min Wei, Pinchas Cohen, Luigi Fontana and Valter D. Longo

    Article first published online : 11 MAR 2013, DOI: 10.1111/acel.12049

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    Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 419–430, Caroline Kumsta, Tsui-Ting Ching, Mayuko Nishimura, Andrew E. Davis, Sara Gelino, Hannah H. Catan, Xiaokun Yu, Chu-Chiao Chu, Binnan Ong, Siler H. Panowski, Nathan Baird, Rolf Bodmer, Ao-Lin Hsu and Malene Hansen

    Article first published online : 9 JAN 2014, DOI: 10.1111/acel.12189

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    Surface L-type Ca2+ channel expression levels are increased in aged hippocampus

    Aging Cell

    Volume 13, Issue 1, February 2014, Pages: 111–120, Félix Luis Núñez-Santana, Myongsoo Matthew Oh, Marcia Diana Antion, Amy Lee, Johannes Wilhelm Hell and John Francis Disterhoft

    Article first published online : 1 OCT 2013, DOI: 10.1111/acel.12157

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    Neuronal glycogen synthesis contributes to physiological aging

    Aging Cell

    Volume 13, Issue 5, October 2014, Pages: 935–945, Christopher Sinadinos, Jordi Valles-Ortega, Laura Boulan, Estel Solsona, Maria F. Tevy, Mercedes Marquez, Jordi Duran, Carmen Lopez-Iglesias, Joaquim Calbó, Ester Blasco, Marti Pumarola, Marco Milán and Joan J. Guinovart

    Article first published online : 25 JUL 2014, DOI: 10.1111/acel.12254

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    Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1110–1121, Haiyang Guo, Zhaojian Liu, Bing Xu, Huili Hu, Zhao Wei, Qiao Liu, Xiyu Zhang, Xuebin Ding, Yu Wang, Minnan Zhao, Yaoqin Gong and Changshun Shao

    Article first published online : 8 SEP 2013, DOI: 10.1111/acel.12138

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    Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes

    Aging Cell

    Volume 14, Issue 1, February 2015, Pages: 35–48, Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Yuan Gao, Li-Rong Yu, Ramani Alla and Robert Shmookler Reis

    Article first published online : 16 DEC 2014, DOI: 10.1111/acel.12296