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There are 39087 results for: content related to: Reductions in serum IGF -1 during aging impair health span

  1. You have full text access to this OnlineOpen article
    Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake

    Aging Cell

    Volume 14, Issue 4, August 2015, Pages: 511–523, Adam P. Sharples, David C. Hughes, Colleen S. Deane, Amarjit Saini, Colin Selman and Claire E. Stewart

    Article first published online : 10 APR 2015, DOI: 10.1111/acel.12342

  2. You have full text access to this OnlineOpen article
    Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: a randomized clinical trial

    Aging Cell

    Volume 15, Issue 1, February 2016, Pages: 22–27, Luigi Fontana, Dennis T. Villareal, Sai K. Das, Steven R. Smith, Simin N. Meydani, Anastassios G. Pittas, Samuel Klein, Manjushri Bhapkar, James Rochon, Eric Ravussin, John O. Holloszy and for the CALERIE Study Group

    Article first published online : 6 OCT 2015, DOI: 10.1111/acel.12400

  3. You have full text access to this OnlineOpen article
    Interventions to Slow Aging in Humans: Are We Ready?

    Aging Cell

    Volume 14, Issue 4, August 2015, Pages: 497–510, Valter D. Longo, Adam Antebi, Andrzej Bartke, Nir Barzilai, Holly M. Brown-Borg, Calogero Caruso, Tyler J. Curiel, Rafael de Cabo, Claudio Franceschi, David Gems, Donald K. Ingram, Thomas E. Johnson, Brian K. Kennedy, Cynthia Kenyon, Samuel Klein, John J. Kopchick, Guenter Lepperdinger, Frank Madeo, Mario G. Mirisola, James R. Mitchell, Giuseppe Passarino, Karl L. Rudolph, John M. Sedivy, Gerald S. Shadel, David A. Sinclair, Stephen R. Spindler, Yousin Suh, Jan Vijg, Manlio Vinciguerra and Luigi Fontana

    Article first published online : 22 APR 2015, DOI: 10.1111/acel.12338

  4. You have full text access to this OnlineOpen article
    Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging

    Aging Cell

    Volume 13, Issue 6, December 2014, Pages: 981–1000, Oge Arum, Ravneet K. Boparai, Jamal K. Saleh, Feiya Wang, Angela L. Dirks, Jeremy G. Turner, John J. Kopchick, Jun-Li Liu, Romesh K. Khardori and Andrzej Bartke

    Article first published online : 20 SEP 2014, DOI: 10.1111/acel.12262

  5. You have full text access to this Open Access content
    Protein restriction cycles reduce IGF-1 and phosphorylated Tau, and improve behavioral performance in an Alzheimer's disease mouse model

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 257–268, Edoardo Parrella, Tom Maxim, Francesca Maialetti, Lu Zhang, Junxiang Wan, Min Wei, Pinchas Cohen, Luigi Fontana and Valter D. Longo

    Article first published online : 11 MAR 2013, DOI: 10.1111/acel.12049

  6. You have full text access to this OnlineOpen article
    IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

    Aging Cell

    Volume 14, Issue 6, December 2015, Pages: 1034–1044, Peter Toth, Stefano Tarantini, Nicole M. Ashpole, Zsuzsanna Tucsek, Ginger L. Milne, Noa M. Valcarcel-Ares, Akos Menyhart, Eszter Farkas, William E. Sonntag, Anna Csiszar and Zoltan Ungvari

    Article first published online : 14 JUL 2015, DOI: 10.1111/acel.12372

  7. You have full text access to this OnlineOpen article
    Effects of nutritional components on aging

    Aging Cell

    Volume 14, Issue 1, February 2015, Pages: 8–16, Dongyeop Lee, Wooseon Hwang, Murat Artan, Dae-Eun Jeong and Seung-Jae Lee

    Article first published online : 22 OCT 2014, DOI: 10.1111/acel.12277

  8. You have full text access to this OnlineOpen article
    Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice

    Aging Cell

    Volume 14, Issue 6, December 2015, Pages: 1045–1054, Marianna Sadagurski, Taylor Landeryou, Gillian Cady, John J. Kopchick, Edward O. List, Darlene E. Berryman, Andrzej Bartke and Richard A. Miller

    Article first published online : 12 AUG 2015, DOI: 10.1111/acel.12382

  9. You have full text access to this OnlineOpen article
    Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

    Aging Cell

    Rute Martins, Gordon J. Lithgow and Wolfgang Link

    Article first published online : 8 DEC 2015, DOI: 10.1111/acel.12427

  10. You have full text access to this OnlineOpen article
    Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline

    Aging Cell

    Volume 15, Issue 1, February 2016, Pages: 181–186, Derek M. Huffman, Gabriela Farias Quipildor, Kai Mao, Xueying Zhang, Junxiang Wan, Pasha Apontes, Pinchas Cohen and Nir Barzilai

    Article first published online : 4 NOV 2015, DOI: 10.1111/acel.12415

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    Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-223 expressions: a study on postmenopausal monozygotic twin pairs

    Aging Cell

    Volume 13, Issue 5, October 2014, Pages: 850–861, Fabiola Olivieri, Maarit Ahtiainen, Raffaella Lazzarini, Eija Pöllänen, Miriam Capri, Maria Lorenzi, Gianluca Fulgenzi, Maria C. Albertini, Stefano Salvioli, Markku J. Alen, Urho M. Kujala, Giulia Borghetti, Lucia Babini, Jaakko Kaprio, Sarianna Sipilä, Claudio Franceschi, Vuokko Kovanen and Antonio D. Procopio

    Article first published online : 18 JUL 2014, DOI: 10.1111/acel.12245

  12. You have full text access to this OnlineOpen article
    Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence

    Aging Cell

    Volume 13, Issue 4, August 2014, Pages: 669–678, Duc Tran, Johann Bergholz, Haibo Zhang, Hanbing He, Yang Wang, Yujun Zhang, Qintong Li, James L. Kirkland and Zhi-Xiong Xiao

    Article first published online : 30 APR 2014, DOI: 10.1111/acel.12219

  13. You have full text access to this Open Access content
    Longevity effect of IGF-1R+/− mutation depends on genetic background-specific receptor activation

    Aging Cell

    Volume 13, Issue 1, February 2014, Pages: 19–28, Jie Xu, Géraldine Gontier, Zayna Chaker, Philippe Lacube, Joëlle Dupont and Martin Holzenberger

    Article first published online : 11 SEP 2013, DOI: 10.1111/acel.12145

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    Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1073–1081, Keunhee Seo, Eunseok Choi, Dongyeop Lee, Dae-Eun Jeong, Sung Key Jang and Seung-Jae Lee

    Article first published online : 4 SEP 2013, DOI: 10.1111/acel.12140

  15. You have full text access to this OnlineOpen article
    Optimal body weight for health and longevity: bridging basic, clinical, and population research

    Aging Cell

    Volume 13, Issue 3, June 2014, Pages: 391–400, Luigi Fontana and Frank B. Hu

    Article first published online : 14 MAR 2014, DOI: 10.1111/acel.12207

  16. You have full text access to this OnlineOpen article
    Parkinson's disease as a result of aging

    Aging Cell

    Volume 14, Issue 3, June 2015, Pages: 293–308, Manuel Rodriguez, Clara Rodriguez-Sabate, Ingrid Morales, Alberto Sanchez and Magdalena Sabate

    Article first published online : 9 FEB 2015, DOI: 10.1111/acel.12312

  17. You have full text access to this OnlineOpen article
    Rifampicin reduces advanced glycation end products and activates DAF-16 to increase lifespan in Caenorhabditis elegans

    Aging Cell

    Volume 14, Issue 3, June 2015, Pages: 463–473, Sandeep Golegaonkar, Syed S. Tabrez, Awadhesh Pandit, Shalini Sethurathinam, Mashanipalya G. Jagadeeshaprasad, Sneha Bansode, Srinivasa-Gopalan Sampathkumar, Mahesh J. Kulkarni and Arnab Mukhopadhyay

    Article first published online : 26 FEB 2015, DOI: 10.1111/acel.12327

  18. You have full text access to this Open Access content
    PTEN controls β-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a

    Aging Cell

    Volume 12, Issue 6, December 2013, Pages: 1000–1011, Ni Zeng, Kai-Ting Yang, Jennifer-Ann Bayan, Lina He, Richa Aggarwal, Joseph W. Stiles, Xiaogang Hou, Vivian Medina, Danny Abad, Beth M. Palian, Ismail Al-Abdullah, Fouad Kandeel, Deborah L. Johnson and Bangyan L. Stiles

    Article first published online : 6 AUG 2013, DOI: 10.1111/acel.12132

  19. You have full text access to this Open Access content
    Quantification of in vivo oxidative damage in Caenorhabditis elegans during aging by endogenous F3-isoprostane measurement

    Aging Cell

    Volume 12, Issue 2, April 2013, Pages: 214–223, Christiaan F. Labuschagne, Edwin C. A. Stigter, Margriet M. W. B. Hendriks, Ruud Berger, Joshua Rokach, Hendrik C. Korswagen and Arjan B. Brenkman

    Article first published online : 30 JAN 2013, DOI: 10.1111/acel.12043

  20. You have full text access to this OnlineOpen article
    A peroxiredoxin, PRDX-2, is required for insulin secretion and insulin/IIS-dependent regulation of stress resistance and longevity

    Aging Cell

    Volume 14, Issue 4, August 2015, Pages: 558–568, Monika Oláhová and Elizabeth A. Veal

    Article first published online : 23 MAR 2015, DOI: 10.1111/acel.12321