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There are 9611 results for: content related to: A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction

  1. You have free access to this content
    4β-Hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin

    British Journal of Clinical Pharmacology

    Volume 67, Issue 1, January 2009, Pages: 38–43, Ulf Diczfalusy, Kajsa P. Kanebratt, Eva Bredberg, Tommy B. Andersson, Ylva Böttiger and Leif Bertilsson

    Version of Record online : 19 SEP 2008, DOI: 10.1111/j.1365-2125.2008.03309.x

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    Time course of the increase in 4β-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy

    British Journal of Clinical Pharmacology

    Volume 65, Issue 5, May 2008, Pages: 708–715, Katarina Wide, Hanna Larsson, Leif Bertilsson and Ulf Diczfalusy

    Version of Record online : 13 FEB 2008, DOI: 10.1111/j.1365-2125.2007.03078.x

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    Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 78, Issue 5, November 2014, Pages: 1122–1134, Sreeneeranj Kasichayanula, David W. Boulton, Wen-Lin Luo, A. David Rodrigues, Zheng Yang, Angela Goodenough, Michelle Lee, Mohammed Jemal and Frank LaCreta

    Version of Record online : 20 OCT 2014, DOI: 10.1111/bcp.12425

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    Effect of Statin Treatment on Plasma 4β-Hydroxycholesterol Concentrations

    Basic & Clinical Pharmacology & Toxicology

    Volume 118, Issue 6, June 2016, Pages: 499–502, Linda Björkhem-Bergman, Hanna Nylén, Mats Eriksson, Paolo Parini and Ulf Diczfalusy

    Version of Record online : 14 JAN 2016, DOI: 10.1111/bcpt.12537

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    CYP3A5 polymorphism affects the increase in CYP3A activity after living kidney transplantation in patients with end stage renal disease

    British Journal of Clinical Pharmacology

    Volume 80, Issue 6, December 2015, Pages: 1421–1428, Yosuke Suzuki, Takashi Fujioka, Fuminori Sato, Kunihiro Matsumoto, Nanako Muraya, Ryota Tanaka, Yuhki Sato, Keiko Ohno, Hiromitsu Mimata, Satoshi Kishino and Hiroki Itoh

    Version of Record online : 3 OCT 2015, DOI: 10.1111/bcp.12733

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    4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes

    British Journal of Clinical Pharmacology

    Volume 80, Issue 3, September 2015, Pages: 560–568, Anne-Joy M. de Graan, Alex Sparreboom, Peter de Bruijn, Evert de Jonge, Bronno van der Holt, Erik A. C. Wiemer, Jaap Verweij, Ron H. J. Mathijssen and Ron H. N. van Schaik

    Version of Record online : 12 AUG 2015, DOI: 10.1111/bcp.12707

  7. Cytochrome P450 Induction by Rifampicin in Healthy Subjects: Determination Using the Karolinska Cocktail and the Endogenous CYP3A4 Marker 4β-Hydroxycholesterol

    Clinical Pharmacology & Therapeutics

    Volume 84, Issue 5, November 2008, Pages: 589–594, KP Kanebratt, U Diczfalusy, T Bäckström, E Sparve, E Bredberg, Y Böttiger, TB Andersson and L Bertilsson

    Version of Record online : 23 JUL 2008, DOI: 10.1038/clpt.2008.132

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    4β-hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans

    British Journal of Clinical Pharmacology

    Volume 71, Issue 2, February 2011, Pages: 183–189, Ulf Diczfalusy, Hanna Nylén, Pontus Elander and Leif Bertilsson

    Version of Record online : 10 JAN 2011, DOI: 10.1111/j.1365-2125.2010.03773.x

  9. Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance

    British Journal of Clinical Pharmacology

    Volume 82, Issue 6, December 2016, Pages: 1539–1549, Thomas Vanhove, Hylke de Jonge, Henriëtte de Loor, Pieter Annaert, Ulf Diczfalusy and Dirk R. J. Kuypers

    Version of Record online : 20 SEP 2016, DOI: 10.1111/bcp.13083

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    Coadministration of Rifampin Significantly Reduces Odanacatib Concentrations in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 57, Issue 1, January 2017, Pages: 110–117, S. Aubrey Stoch, Jeanine Ballard, Christopher Gibson, Filippos Kesisoglou, Rose Witter, Kelem Kassahun, Stefan Zajic, Anish Mehta, Christine Brandquist, Cynthia Dempsey, Daria Stypinski and Marc L. Reitman

    Version of Record online : 1 AUG 2016, DOI: 10.1002/jcph.780

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    Plasma Levels of 25-Hydroxyvitamin D3 and In Vivo Markers of Cytochrome P450 3A Activity in Swedes and Koreans: Effects of a Genetic Polymorphism and Oral Contraceptives

    Basic & Clinical Pharmacology & Toxicology

    Volume 115, Issue 4, October 2014, Pages: 366–371, Hanna Nylén, Linda Björkhem-Bergman, Lena Ekström, Hyung-Keun Roh, Leif Bertilsson, Erik Eliasson, Jonatan D. Lindh and Ulf Diczfalusy

    Version of Record online : 11 APR 2014, DOI: 10.1111/bcpt.12230

  12. Evaluation of Endogenous Metabolic Markers of Hepatic CYP3A Activity Using Metabolic Profiling and Midazolam Clearance

    Clinical Pharmacology & Therapeutics

    Volume 94, Issue 5, November 2013, Pages: 601–609, K-H Shin, M H Choi, K S Lim, K-S Yu, I-J Jang and J-Y Cho

    Version of Record online : 19 JUN 2013, DOI: 10.1038/clpt.2013.128

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    Cholesterol Oxidation in Fish and Fish Products

    Journal of Food Science

    Volume 80, Issue 12, December 2015, Pages: R2627–R2639, Natalie Marinho Dantas, Geni Rodrigues Sampaio, Fernanda Silva Ferreira, Tatiana da Silva Labre, Elizabeth Aparecida Ferraz da Silva Torres and Tatiana Saldanha

    Version of Record online : 10 NOV 2015, DOI: 10.1111/1750-3841.13124

  14. Evaluation of 6β-Hydroxycortisol, 6β-Hydroxycortisone, and a Combination of the Two as Endogenous Probes for Inhibition of CYP3A4 In Vivo

    Clinical Pharmacology & Therapeutics

    Volume 89, Issue 6, June 2011, Pages: 888–895, C-C Peng, I Templeton, KE Thummel, C Davis, KL Kunze and N Isoherranen

    Version of Record online : 13 APR 2011, DOI: 10.1038/clpt.2011.53

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    The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity

    British Journal of Clinical Pharmacology

    Volume 80, Issue 3, September 2015, Pages: 473–479, Janne Hukkanen, Johanna Puurunen, Tuulia Hyötyläinen, Markku J. Savolainen, Aimo Ruokonen, Laure Morin-Papunen, Matej Orešič, Terhi Piltonen and Juha S. Tapanainen

    Version of Record online : 22 JUL 2015, DOI: 10.1111/bcp.12701

  16. Plasma 4β-Hydroxycholesterol: An Endogenous CYP3A Metric?

    Clinical Pharmacology & Therapeutics

    Volume 86, Issue 2, August 2009, Pages: 147–153, D Tomalik-Scharte, D Lütjohann, O Doroshyenko, D Frank, A Jetter and U Fuhr

    Version of Record online : 20 MAY 2009, DOI: 10.1038/clpt.2009.72

  17. You have full text access to this OnlineOpen article
    Evaluation of 4β-Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism–Based Pharmacometric Model

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 3, Issue 6, June 2014, Pages: 1–10, TA Leil, S Kasichayanula, DW Boulton and F LaCreta

    Version of Record online : 25 JUN 2014, DOI: 10.1038/psp.2014.18

  18. Does the Long Plasma Half-Life of 4β-Hydroxycholesterol Impact Its Utility as a Cytochrome P450 3A (CYP3A) Metric?

    The Journal of Clinical Pharmacology

    Volume 50, Issue 11, November 2010, Pages: 1330–1338, Zheng Yang and A. David Rodrigues

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009360041

  19. 4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients

    British Journal of Clinical Pharmacology

    Caroline Gjestad, Tore Haslemo, Ole A. Andreassen and Espen Molden

    Version of Record online : 21 JUL 2017, DOI: 10.1111/bcp.13341

  20. Method development for the determination of 24S-hydroxycholesterol in human plasma without derivatization by high-performance liquid chromatography with tandem mass spectrometry in atmospheric pressure chemical ionization mode

    Journal of Separation Science

    Volume 38, Issue 20, October 2015, Pages: 3516–3524, Hiroshi Sugimoto, Masaaki Kakehi, Yoshinori Satomi, Hidenori Kamiguchi and Fumihiro Jinno

    Version of Record online : 10 SEP 2015, DOI: 10.1002/jssc.201500719