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There are 18114 results for: content related to: Clopidogrel variability: role of plasma protein binding alterations

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    Pharmacokinetics and central nervous system effects of the novel dual NK1/NK3 receptor antagonist GSK1144814 in alcohol-intoxicated volunteers

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1328–1339, Erik T. te Beek, Justin L. Hay, Jonathan N. Bullman, Clare Burgess, Kimberly J. Nahon, Erica S. Klaassen, Frank A. Gray and Joop M. A. van Gerven

    Article first published online : 8 APR 2013, DOI: 10.1111/bcp.12004

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    Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men

    British Journal of Clinical Pharmacology

    Volume 75, Issue 6, June 2013, Pages: 1455–1467, Marieke Liem-Moolenaar, Pierre Peeters, Ingrid M. C. Kamerling, Chris Hogg, Graham Holder, Huub Jan Kleijn, Edwin Spaans, Joanna Udo De Haes, Marieke L. de Kam, Kari L. Franson, Adam F. Cohen and Joop M. A. van Gerven

    Article first published online : 20 MAY 2013, DOI: 10.1111/bcp.12015

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    Statistical tools for dose individualization of mycophenolic acid and tacrolimus co-administered during the first month after renal transplantation

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1277–1288, Flora T. Musuamba, Michel Mourad, Vincent Haufroid, Martine De Meyer, Arnaud Capron, Isabelle K. Delattre, Roger K. Verbeeck and Pierre Wallemacq

    Article first published online : 8 APR 2013, DOI: 10.1111/bcp.12007

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    Drug induced QT prolongation: the measurement and assessment of the QT interval in clinical practice

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 48–57, Geoffrey K. Isbister and Colin B. Page

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12040

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    The influence of kidney function on dapagliflozin exposure, metabolism and pharmacodynamics in healthy subjects and in patients with type 2 diabetes mellitus

    British Journal of Clinical Pharmacology

    Volume 76, Issue 3, September 2013, Pages: 432–444, Sreeneeranj Kasichayanula, Xiaoni Liu, Melanie Pe Benito, Ming Yao, Marc Pfister, Frank P. LaCreta, William Griffith Humphreys and David W. Boulton

    Article first published online : 20 AUG 2013, DOI: 10.1111/bcp.12056

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    Validation of suicide and self-harm records in the Clinical Practice Research Datalink

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 145–157, Kyla H. Thomas, Neil Davies, Chris Metcalfe, Frank Windmeijer, Richard M. Martin and David Gunnell

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12059

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    Optimizing drug development of anti-cancer drugs in children using modelling and simulation

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 30–47, Johan G.C. van Hasselt, Natasha K.A. van Eijkelenburg, Jos H. Beijnen, Jan H.M. Schellens and Alwin D.R. Huitema

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12062

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    Bioequipotency of idraparinux and idrabiotaparinux after once weekly dosing in healthy volunteers and patients treated for acute deep vein thrombosis

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1255–1264, Marc Trellu, Jean-Baptiste Fau, Pierre Cortez, Sue Cheng, Isabelle Paty, Emmanuelle Boëlle, François Donat and Ger-Jan Sanderink

    Article first published online : 8 APR 2013, DOI: 10.1111/bcp.12009

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    Antifungal agents and therapy for infants and children with invasive fungal infections: a pharmacological perspective

    British Journal of Clinical Pharmacology

    Volume 75, Issue 6, June 2013, Pages: 1381–1395, Jodi M. Lestner, P. Brian Smith, Michael Cohen-Wolkowiez, Daniel K. Benjamin Jr and William W. Hope

    Article first published online : 20 MAY 2013, DOI: 10.1111/bcp.12025

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    Additional use of an aldosterone antagonist in patients with mild to moderate chronic heart failure: a systematic review and meta-analysis

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1202–1212, Li-jun Hu, Yun-qing Chen, Song-bai Deng, Jian-lin Du and Qiang She

    Article first published online : 8 APR 2013, DOI: 10.1111/bcp.12012

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    Vitamin D3 supplementation scheme in HIV-infected patients based upon pharmacokinetic modelling of 25-hydroxycholecalciferol

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1312–1320, Frantz Foissac, Jean-Marc Tréluyer, Jean-Claude Souberbielle, Hafeda Rostane, Saïk Urien and Jean-Paul Viard

    Article first published online : 8 APR 2013, DOI: 10.1111/bcp.12006

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    Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 125–136, Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M. Richards and Ajay Vora

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12066

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    Grapefruit juice markedly increases the plasma concentrations and antiplatelet effects of ticagrelor in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 75, Issue 6, June 2013, Pages: 1488–1496, Mikko T. Holmberg, Aleksi Tornio, Lotta Joutsi-Korhonen, Mikko Neuvonen, Pertti J. Neuvonen, Riitta Lassila, Mikko Niemi and Janne T. Backman

    Article first published online : 20 MAY 2013, DOI: 10.1111/bcp.12026

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    Romiplostim dose–response in patients with myelodysplastic syndromes

    British Journal of Clinical Pharmacology

    Volume 75, Issue 6, June 2013, Pages: 1445–1454, Juan Jose Perez Ruixo, Sameer Doshi, Yow-Ming C. Wang and Diane R. Mould

    Article first published online : 20 MAY 2013, DOI: 10.1111/bcp.12041

  15. The effectiveness of propranolol in treating infantile haemangiomas: a meta-analysis including 35 studies

    British Journal of Clinical Pharmacology

    Volume 78, Issue 1, July 2014, Pages: 44–57, Yin Lou, Wen-jia Peng, Yi Cao, Dong-sheng Cao, Juan Xie and Hong-hong Li

    Article first published online : 20 JUN 2014, DOI: 10.1111/bcp.12235

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    Effect of hepatic impairment on the pharmacokinetics and pharmacodynamics of a single dose of rivaroxaban, an oral, direct Factor Xa inhibitor

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 89–98, Dagmar Kubitza, Angelika Roth, Michael Becka, Abir Alatrach, Atef Halabi, Holger Hinrichsen and Wolfgang Mueck

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12054

    Corrected by:

    Erratum: Corrigendum

    Vol. 76, Issue 3, 489, Article first published online: 20 AUG 2013

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    A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity

    British Journal of Clinical Pharmacology

    Volume 75, Issue 6, June 2013, Pages: 1433–1444, Joseph A. Jakubowski, Chunmei Zhou, David S. Small, Kenneth J. Winters, D. Richard Lachno, Andrew L. Frelinger III, Jo Howard, Timothy G. Mant, Stipo Jurcevic and Christopher D. Payne

    Article first published online : 20 MAY 2013, DOI: 10.1111/bcp.12042

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    AT1 mutations and risk of atrial fibrillation based on genotypes from 71 000 individuals from the general population

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 114–124, Sarah C. W. Marott, Børge G. Nordestgaard, Gorm B. Jensen, Anne Tybjærg-Hansen and Marianne Benn

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12050

  19. Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials

    British Journal of Clinical Pharmacology

    Volume 76, Issue 5, November 2013, Pages: 649–667, Pritesh N. Bodalia, Anthony M. Grosso, Reecha Sofat, Raymond J. MacAllister, Liam Smeeth, Soraya Dhillon, Juan-Pablo Casas, David Wonderling and Aroon D. Hingorani

    Article first published online : 21 OCT 2013, DOI: 10.1111/bcp.12083

  20. A novel approach to pharmaco-EEG for investigating analgesics: assessment of spectral indices in single-sweep evoked brain potentials

    British Journal of Clinical Pharmacology

    Volume 76, Issue 6, December 2013, Pages: 951–963, Mikkel Gram, Carina Graversen, Anders K. Nielsen, Thomas Arendt-Nielsen, Carsten D. Mørch, Trine Andresen and Asbjørn M. Drewes

    Article first published online : 20 NOV 2013, DOI: 10.1111/bcp.12120