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There are 4549 results for: content related to: Antihyperalgesic Effect of the GABA A Ligand Clobazam in a Neuropathic Pain Model in Mice: A Pharmacokinetic–Pharmacodynamic Study

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    Total Synthetic Protoapigenone WYC02 Inhibits Cervical Cancer Cell Proliferation and Tumour Growth through PIK3 Signalling Pathway

    Basic & Clinical Pharmacology & Toxicology

    Volume 113, Issue 1, July 2013, Pages: 8–18, Yun-Ju Chen, Nari Kay, Jinn-Moon Yang, Chih-Ta Lin, Hsueh-Ling Chang, Yang-Chang Wu, Chi-Feng Fu, Yu Chang, Steven Lo, Ming-Feng Hou, Yi-Chen Lee, Ya-Ching Hsieh and Shyng-Shiou Yuan

    Article first published online : 21 MAR 2013, DOI: 10.1111/bcpt.12057

  2. Anti-inflammatory Effect of Rosmarinic Acid and an Extract of Rosmarinus officinalis in Rat Models of Local and Systemic Inflammation

    Basic & Clinical Pharmacology & Toxicology

    Joao Rocha, Maria Eduardo-Figueira, Andreia Barateiro, Adelaide Fernandes, Dora Brites, Rosario Bronze, Catarina MM Duarte, Ana Teresa Serra, Rui Pinto, Marisa Freitas, Eduarda Fernandes, Beatriz Silva-Lima, Helder Mota-Filipe and Bruno Sepodes

    Article first published online : 6 NOV 2014, DOI: 10.1111/bcpt.12335

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    Pharmacological Characterisation of a Structurally Novel α2C -Adrenoceptor Antagonist ORM-10921 and its Effects in Neuropsychiatric Models

    Basic & Clinical Pharmacology & Toxicology

    Volume 113, Issue 4, October 2013, Pages: 239–249, Jukka Sallinen, Johanna Holappa, Ari Koivisto, Katja Kuokkanen, Hugh Chapman, Jyrki Lehtimäki, Petteri Piepponen, Jelena Mijatovic, Heikki Tanila, Raimo Virtanen, Jouni Sirviö and Antti Haapalinna

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcpt.12090

  4. Acute Exposure to Low Lead Levels and its Implications on the Activity and Expression of Cytosolic Thioredoxin Reductase in the Kidney

    Basic & Clinical Pharmacology & Toxicology

    Volume 114, Issue 6, June 2014, Pages: 476–484, Greicy M. M. Conterato, Andréia Quatrin, Sabrina Somacal, Amanda R. Ruviaro, Juliana Vicentini, Paula R. Augusti, Rocheli Sobieski, Cassieli Figueiredo, Clarissa M. M. dos Santos, Talita C. B. Pereira, Maurício R. Bogo, Erico M. M. Flores and Tatiana Emanuelli

    Article first published online : 25 JAN 2014, DOI: 10.1111/bcpt.12183

  5. Improving Amphetamine Therapeutic Selectivity: N,N-dimethyl-MTA has Dopaminergic Effects and does not Produce Aortic Contraction

    Basic & Clinical Pharmacology & Toxicology

    Volume 114, Issue 5, May 2014, Pages: 395–399, Ramón Sotomayor-Zárate, Pablo Jara, Patricio Araos, Raúl Vinet, Gabriel Quiroz, Georgina M. Renard, Pedro Espinosa, Claudio Hurtado-Guzmán, Pablo R. Moya, Patricio Iturriaga-Vásquez, Katia Gysling and Miguel Reyes-Parada

    Article first published online : 7 DEC 2013, DOI: 10.1111/bcpt.12168

  6. Inhibition of UVB-Induced Skin Damage by Exopolymers from Aureobasidium pullulansSM-2001 in Hairless Mice

    Basic & Clinical Pharmacology & Toxicology

    Kyung Hu Kim, Soo Jin Park, Young Joon Lee, Ji Eun Lee, Chang Hyun Song, Seong Hun Choi, Sae Kwang Ku and Su Jin Kang

    Article first published online : 6 AUG 2014, DOI: 10.1111/bcpt.12288

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    Dexamethasone-eluting Vascular Stents

    Basic & Clinical Pharmacology & Toxicology

    Volume 112, Issue 5, May 2013, Pages: 296–301, Mari Hämäläinen, Riina Nieminen, Ilkka Uurto, Juha-Pekka Salenius, Minna Kellomäki, Joonas Mikkonen, Andres Kotsar, Taina Isotalo, Teuvo Tammela LJ, Martti Talja and Eeva Moilanen

    Article first published online : 9 MAR 2013, DOI: 10.1111/bcpt.12056

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    L-Amino Acid Oxidase Isolated from Bothrops pirajai Induces Apoptosis in BCR-ABL-Positive Cells and Potentiates Imatinib Mesylate Effect

    Basic & Clinical Pharmacology & Toxicology

    Volume 113, Issue 2, August 2013, Pages: 103–112, Sandra M. Burin, Lorena R. Ayres, Renata P. Neves, Luciana Ambrósio, Fabiana R. de Morais, Marcelo Dias-Baruffi, Suely V. Sampaio, Luciana S. Pereira-Crott and Fabíola A. de Castro

    Article first published online : 20 MAY 2013, DOI: 10.1111/bcpt.12073

  9. Does Bosentan Protect Diabetic Brain Alterations in Rats? The Role of Endothelin-1 in the Diabetic Brain

    Basic & Clinical Pharmacology & Toxicology

    Recep Demir, Elif Cadirci, Erol Akpinar, Yasemin Cayir, Hasan Tarik Atmaca, Harun Un, Celalettin Semih Kunak, Muhammed Yayla, Zafer Bayraktutan and Ilknur Demir

    Article first published online : 7 OCT 2014, DOI: 10.1111/bcpt.12318

  10. Geraniol Blocks Calcium and Potassium Channels in the Mammalian Myocardium: Useful Effects to Treat Arrhythmias

    Basic & Clinical Pharmacology & Toxicology

    Volume 115, Issue 6, December 2014, Pages: 534–544, José Evaldo Rodrigues de Menezes-Filho, Antônio Nei Santana Gondim, Jader Santos Cruz, Américo Azevedo de Souza, José Nilson Andrade dos Santos, Eduardo Antônio Conde-Garcia, Damião Pergentino de Sousa, Michel Santana Santos, Evaleide Diniz de Oliveira and Carla Maria Lins de Vasconcelos

    Article first published online : 4 JUL 2014, DOI: 10.1111/bcpt.12274

  11. Peripheral Antinociception and Anti-Inflammatory Effects of Sulphated Polysaccharides from the Alga Caulerpa mexicana

    Basic & Clinical Pharmacology & Toxicology

    Volume 115, Issue 4, October 2014, Pages: 335–342, José Gerardo Carneiro, José Ariévilo Gurgel Rodrigues, Edfranck de Sousa Oliveira Vanderlei, Ricardo Basto Souza, Ana Luíza Gomes Quinderé, Chistiane Oliveira Coura, Ianna Wivianne Fernandes de Araújo, Hellíada Vasconcelos Chaves, Mirna Marques Bezerra and Norma Maria Barros Benevides

    Article first published online : 18 APR 2014, DOI: 10.1111/bcpt.12234

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    Metformin Induces Cytotoxicity by Down-Regulating Thymidine Phosphorylase and Excision Repair Cross-Complementation 1 Expression in Non-Small Cell Lung Cancer Cells

    Basic & Clinical Pharmacology & Toxicology

    Volume 113, Issue 1, July 2013, Pages: 56–65, Jen-Chung Ko, Yu-Ching Huang, Huang-Jen Chen, Sheng-Chieh Tseng, Hsien-Chun Chiu, Ting-Yu Wo, Yi-Jhen Huang, Shao-Hsing Weng, Robin Y. Y. Chiou and Yun-Wei Lin

    Article first published online : 21 MAR 2013, DOI: 10.1111/bcpt.12052

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    Quercetin Decreases Liver Damage in Mice with Non-Alcoholic Steatohepatitis

    Basic & Clinical Pharmacology & Toxicology

    Volume 112, Issue 6, June 2013, Pages: 385–391, Éder Marcolin, Luiz Felipe Forgiarini, Graziella Rodrigues, Juliana Tieppo, Greice Stefani Borghetti, Valquiria Linck Bassani, Jaqueline Nascimento Picada and Norma Possa Marroni

    Article first published online : 21 MAR 2013, DOI: 10.1111/bcpt.12049

  14. Cumulative Mitoxantrone-Induced Haematological and Hepatic Adverse Effects in a Subchronic In vivo Study

    Basic & Clinical Pharmacology & Toxicology

    Volume 114, Issue 3, March 2014, Pages: 254–262, Luciana G. Rossato, Vera M. Costa, Eliane Dallegrave, Marcelo Arbo, Ricardo J. Dinis-Oliveira, Alice Santos-Silva, José A. Duarte, Maria de Lourdes Bastos, Carlos Palmeira and Fernando Remião

    Article first published online : 1 NOV 2013, DOI: 10.1111/bcpt.12143

  15. β-Cyclodextrin Complex Containing Lippia grata Leaf Essential Oil Reduces Orofacial Nociception in Mice – Evidence of Possible Involvement of Descending Inhibitory Pain Modulation Pathway

    Basic & Clinical Pharmacology & Toxicology

    Volume 114, Issue 2, February 2014, Pages: 188–196, Pollyana S. Siqueira-Lima, Adriano A. S. Araújo, Angélica M. Lucchese, Jullyana S. S. Quintans, Paula P. Menezes, Péricles B. Alves, Waldecy de Lucca Júnior, Marcio R. V. Santos, Leonardo R. Bonjardim and Lucindo J. Quintans-Júnior

    Article first published online : 8 NOV 2013, DOI: 10.1111/bcpt.12145

  16. Acute Effects of Dipyrone on Renal Function in Patients with Cirrhosis: A Randomized Controlled Trial

    Basic & Clinical Pharmacology & Toxicology

    Pedro Zapater, Lucia Llanos, Claudia Barquero, Pablo Bellot, Sonia Pascual, Fernando Carnicer, Jose Maria Palazón, Paula Gimenez, Angel Esteban, Lourdes Llorca, Ruben Francés, Jose Francisco Horga and Jose Such

    Article first published online : 7 OCT 2014, DOI: 10.1111/bcpt.12312

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    In Utero and Lactational Exposure to Fluoxetine in Wistar Rats: Pregnancy Outcomes and Sexual Development

    Basic & Clinical Pharmacology & Toxicology

    Volume 113, Issue 2, August 2013, Pages: 132–140, Juliane C. Müller, Ana C. Boareto, Emerson L. B. Lourenço, Renata M. Zaia, Mariana F. Kienast, Katherinne M. Spercoski, Rosana N. Morais, Anderson J. Martino-Andrade and Paulo R. Dalsenter

    Article first published online : 7 MAY 2013, DOI: 10.1111/bcpt.12072

  18. The Inhibitory Effect of Intravesical Fisetin against Bladder Cancer by Induction of p53 and Down-Regulation of NF-kappa B Pathways in a Rat Bladder Carcinogenesis Model

    Basic & Clinical Pharmacology & Toxicology

    Volume 115, Issue 4, October 2014, Pages: 321–329, Jing Li, Weixing Qu, Yongyi Cheng, Yi Sun, Yazhuo Jiang, Tiejun Zou, Zhiping Wang, Yonggang Xu and Huacai Zhao

    Article first published online : 5 APR 2014, DOI: 10.1111/bcpt.12229

  19. Diphenyl Ditelluride-Induced Cell Cycle Arrest and Apoptosis: A Relation with Topoisomerase I Inhibition

    Basic & Clinical Pharmacology & Toxicology

    Patrícia M. Jorge, Iuri M. de Oliveira, Eduardo C. Filippi Chiela, Cassiana M. Viau, Jenifer Saffi, Fabiana Horn, Renato M. Rosa, Temenouga N. Guecheva and João A. Pêgas Henriques

    Article first published online : 6 OCT 2014, DOI: 10.1111/bcpt.12315

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    Beneficial Pharmacological Effects of Levosimendan on Antioxidant Status of Acute Inflammation Induced in Paw of Rat: Involvement in Inflammatory Mediators

    Basic & Clinical Pharmacology & Toxicology

    Volume 112, Issue 3, March 2013, Pages: 156–163, Emre Karakus, Zekai Halici, Abdulmecit Albayrak, Yasin Bayir, Ali Aydin, Deniz Unal, Elif Cadirci, Irmak Ferah and Ersan Odaci

    Article first published online : 17 OCT 2012, DOI: 10.1111/bcpt.12004