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There are 8370 results for: content related to: Potent in vitro and in vivo activity of sorafenib in multiple myeloma: induction of cell death, CD 138-downregulation and inhibition of migration through actin depolymerization

  1. Nuclear factor kappa B–mediated CD47 up-regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice


    Volume 62, Issue 2, August 2015, Pages: 534–545, Jessica Lo, Eunice Yuen Ting Lau, Rachel Hiu Ha Ching, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Irene Oi Lin Ng and Terence Kin Wah Lee

    Article first published online : 3 JUN 2015, DOI: 10.1002/hep.27859

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    Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 8b, August 2009, Pages: 2673–2683, Hung Huynh, Van Chanh Ngo, Heng Nung Koong, Donald Poon, Su Pin Choo, Choon Hua Thng, Pierce Chow, Hock Soo Ong, Alexander Chung and Khee Chee Soo

    Article first published online : 11 FEB 2009, DOI: 10.1111/j.1582-4934.2009.00692.x

  3. You have full text access to this OnlineOpen article
    Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

    International Journal of Cancer

    Volume 136, Issue 6, 15 March 2015, Pages: 1434–1444, Floris H. Groenendijk, Wouter W. Mellema, Eline van der Burg, Eva Schut, Michael Hauptmann, Hugo M. Horlings, Stefan M. Willems, Michel M. van den Heuvel, Jos Jonkers, Egbert F. Smit and René Bernards

    Article first published online : 8 AUG 2014, DOI: 10.1002/ijc.29113

  4. You have full text access to this OnlineOpen article
    GRP78/Dna K Is a Target for Nexavar/Stivarga/Votrient in the Treatment of Human Malignancies, Viral Infections and Bacterial Diseases

    Journal of Cellular Physiology

    Volume 230, Issue 10, October 2015, Pages: 2552–2578, Jane L. Roberts, Mehrad Tavallai, Aida Nourbakhsh, Abigail Fidanza, Tanya Cruz-Luna, Elizabeth Smith, Paul Siembida, Pascale Plamondon, Kelly A. Cycon, Christopher D. Doern, Laurence Booth and Paul Dent

    Article first published online : 23 JUN 2015, DOI: 10.1002/jcp.25014

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    Sorafenib relieves cell-intrinsic and cell-extrinsic inhibitions of effector T cells in tumor microenvironment to augment antitumor immunity

    International Journal of Cancer

    Volume 134, Issue 2, 15 January 2014, Pages: 319–331, Mei-Ling Chen, Bo-Shiun Yan, Wan-Chih Lu, Mei-Huei Chen, Sung-Liang Yu, Pan-Chyr Yang and Ann-Lii Cheng

    Article first published online : 30 JUL 2013, DOI: 10.1002/ijc.28362

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    Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2


    Volume 50, Issue 6, December 2009, Pages: 1861–1870, Boris R. A. Blechacz, Rory L. Smoot, Steven F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica and Gregory J. Gores

    Article first published online : 5 AUG 2009, DOI: 10.1002/hep.23214

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    Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib – the role of extracellular signal-regulated kinase counteraction

    FEBS Journal

    Volume 278, Issue 18, September 2011, Pages: 3494–3507, Irena Manov, Yulia Pollak, Rinata Broneshter and Theodore C. Iancu

    Article first published online : 5 SEP 2011, DOI: 10.1111/j.1742-4658.2011.08271.x

  8. Sorafenib induces endometrial carcinoma apoptosis by inhibiting Elk-1-dependent Mcl-1 transcription and inducing Akt/GSK3β-dependent protein degradation

    Journal of Cellular Biochemistry

    Volume 114, Issue 8, August 2013, Pages: 1819–1831, Nian-Kang Sun, Shang-Lang Huang, Ting-Chang Chang and Chuck C.-K. Chao

    Article first published online : 11 JUN 2013, DOI: 10.1002/jcb.24530

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    EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib

    International Journal of Cancer

    Volume 131, Issue 12, 15 December 2012, Pages: 2961–2969, Zakaria Ezzoukhry, Christophe Louandre, Eric Trécherel, Corinne Godin, Bruno Chauffert, Sébastien Dupont, Momar Diouf, Jean-Claude Barbare, Jean-Claude Mazière and Antoine Galmiche

    Article first published online : 30 APR 2012, DOI: 10.1002/ijc.27604

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    Sorafenib, a multikinase inhibitor, is effective in vitro against non-hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin

    American Journal of Hematology

    Volume 87, Issue 3, March 2012, Pages: 277–283, Vijay Ramakrishnan, Michael Timm, Jessica L. Haug, Teresa K. Kimlinger, Timothy Halling, Linda E. Wellik, Thomas E. Witzig, S. Vincent Rajkumar, Alex A. Adjei and Shaji Kumar

    Article first published online : 21 DEC 2011, DOI: 10.1002/ajh.22263

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    Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update

    Hepatology Research

    Volume 43, Issue 2, February 2013, Pages: 147–154, Angela Gauthier and Mitchell Ho

    Article first published online : 12 NOV 2012, DOI: 10.1111/j.1872-034X.2012.01113.x

  12. Clinical outcome of sorafenib treatment in patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy

    Journal of Gastroenterology and Hepatology

    Volume 28, Issue 12, December 2013, Pages: 1834–1841, Daisuke Miyaki, Hiroshi Aikata, Hiromi Kan, Hatsue Fujino, Ayako Urabe, Keiichi Masaki, Takayuki Fukuhara, Tomoki Kobayashi, Noriaki Naeshiro, Takashi Nakahara, Tomokazu Kawaoka, Akira Hiramatsu, Shoichi Takahashi, Masaki Ishikawa, Hideaki Kakizawa, Kazuo Awai and Kazuaki Chayama

    Article first published online : 22 NOV 2013, DOI: 10.1111/jgh.12311

  13. Effects of Antitumor Drug Sorafenib on Chick Embryo Development

    The Anatomical Record

    Volume 298, Issue 7, July 2015, Pages: 1271–1281, Yi-Sen Cheng, Xiao-Yu Wang, Guang Wang, Yan Li, Yue-Lei Chen, Man-li Chuai, Kenneth Ka Ho Lee, Xiao-Yan Ding and Xue-song Yang

    Article first published online : 17 APR 2015, DOI: 10.1002/ar.23155

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    Molecular analysis of sunitinib resistant renal cell carcinoma cells after sequential treatment with RAD001 (everolimus) or sorafenib

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 2, February 2015, Pages: 430–441, Eva Juengel, Dana Kim, Jasmina Makarević, Michael Reiter, Igor Tsaur, Georg Bartsch, Axel Haferkamp and Roman A. Blaheta

    Article first published online : 2 DEC 2014, DOI: 10.1111/jcmm.12471

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    Sorafenib inhibits transforming growth factor β1-Mediated Epithelial-Mesenchymal Transition and apoptosis in mouse hepatocytes


    Volume 53, Issue 5, May 2011, Pages: 1708–1718, Yue-Lei Chen, Jing Lv, Xiao-Lei Ye, Ming-Yu Sun, Qin Xu, Cheng-Hai Liu, Li-Hua Min, Hui-Ping Li, Ping Liu and Xiaoyan Ding

    Article first published online : 22 APR 2011, DOI: 10.1002/hep.24254

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    A new patient-focused approach to the treatment of metastatic renal cell carcinoma: establishing customized treatment options

    BJU International

    Volume 107, Issue 8, April 2011, Pages: 1190–1199, Joaquim Bellmunt, Tim Eisen, Cezary Szczylik, Peter Mulders and Camillo Porta

    Article first published online : 15 NOV 2010, DOI: 10.1111/j.1464-410X.2010.09829.x

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    ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21(CIP1/WAF1) in human cancer cells

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3182–3195, Jingru Li, Yicheng Chen, Jiali Wan, Xin Liu, Chunrong Yu and Wenhua Li

    Article first published online : 10 JUN 2014, DOI: 10.1111/bph.12659

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    Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats


    Volume 49, Issue 4, April 2009, Pages: 1245–1256, Marc Mejias, Ester Garcia-Pras, Carolina Tiani, Rosa Miquel, Jaime Bosch and Mercedes Fernandez

    Article first published online : 25 NOV 2008, DOI: 10.1002/hep.22758

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    FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity

    Pharmacology Research & Perspectives

    Volume 3, Issue 5, October 2015, Dilruba Ahmed, Petra J. de Verdier, Charlotta Ryk, Oscar Lunqe, Per Stål and Jenny Flygare

    Article first published online : 19 AUG 2015, DOI: 10.1002/prp2.171

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    Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib


    Volume 56, Issue 6, December 2012, Pages: 2363–2374, Carlo Spirli, Carola M. Morell, Luigi Locatelli, Stefano Okolicsanyi, Cecilia Ferrero, Amy K. Kim, Luca Fabris, Romina Fiorotto and Mario Strazzabosco

    Article first published online : 27 AUG 2012, DOI: 10.1002/hep.25872