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There are 4353 results for: content related to: Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors

  1. You have free access to this content
    The tyrosine kinase inhibitor dasatinib reduces lung inflammation and remodelling in experimental allergic asthma

    British Journal of Pharmacology

    Volume 173, Issue 7, April 2016, Pages: 1236–1247, AL da Silva, RF Magalhães, VC Branco, JD Silva, FF Cruz, PS Marques, TPT Ferreira, MM Morales, MA Martins, PC Olsen and PRM Rocco

    Version of Record online : 25 FEB 2016, DOI: 10.1111/bph.13430

  2. Phase I Study of the Effect of Gastric Acid pH Modulators on the Bioavailability of Oral Dasatinib in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 49, Issue 6, June 2009, Pages: 700–709, Dr Timothy Eley, Dr Feng R. Luo, Dr Shruti Agrawal, Dr Ashish Sanil, Dr James Manning, Dr Tong Li, Dr Anne Blackwood-Chirchir and Dr Richard Bertz

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009333854

  3. Pharmacogenomics of Dasatinib (Sprycel™)

    Kinase Inhibitor Drugs

    Fei Huang, Edwin A. Clark, Pages: 365–402, 2009

    Published Online : 28 SEP 2009, DOI: 10.1002/9780470524961.ch15

  4. Dasatinib inhibits mammary tumour development in a genetically engineered mouse model

    The Journal of Pathology

    Volume 230, Issue 4, August 2013, Pages: 430–440, Saadia A Karim, Helen Creedon, Hitesh Patel, Neil O Carragher, Jennifer P Morton, William J Muller, Thomas RJ Evans, Barry Gusterson, Owen J Sansom and Valerie G Brunton

    Version of Record online : 9 JUL 2013, DOI: 10.1002/path.4202

  5. You have full text access to this OnlineOpen article
    Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells

    British Journal of Pharmacology

    Volume 172, Issue 15, August 2015, Pages: 3805–3816, Wing S To, Susan R Aungier, Alison J Cartwright, Kazuhiro Ito and Kim S Midwood

    Version of Record online : 12 JUN 2015, DOI: 10.1111/bph.13170

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    The tyrosine kinase inhibitor bafetinib inhibits PAR2-induced activation of TRPV4 channels in vitro and pain in vivo

    British Journal of Pharmacology

    Volume 171, Issue 16, August 2014, Pages: 3881–3894, M S Grace, T Lieu, B Darby, F C Abogadie, N Veldhuis, N W Bunnett and P McIntyre

    Version of Record online : 25 JUL 2014, DOI: 10.1111/bph.12750

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    Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells

    British Journal of Pharmacology

    Volume 172, Issue 1, January 2015, Pages: 50–63, Divya Pathania, Yuting Kuang, Mario Sechi and Nouri Neamati

    Version of Record online : 19 DEC 2014, DOI: 10.1111/bph.12855

  8. Targeting Fyn in Ras-transformed cells induces F-actin to promote adherens junction-mediated cell–cell adhesion

    Molecular Carcinogenesis

    Volume 54, Issue 10, October 2015, Pages: 1181–1193, Sarah E. Fenton, Kelli A. Hutchens and Mitchell F. Denning

    Version of Record online : 29 JUN 2014, DOI: 10.1002/mc.22190

  9. You have free access to this content
    Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib

    International Journal of Cancer

    Volume 131, Issue 6, 15 September 2012, Pages: E916–E927, Nicole Hassold, Katharina Seystahl, Kristina Kempf, Doris Urlaub, Michael Zekl, Hermann Einsele, Carsten Watzl, Jörg Wischhusen and Ruth Seggewiss-Bernhardt

    Version of Record online : 4 APR 2012, DOI: 10.1002/ijc.27537

  10. Dasatinib inhibits progenitor cell proliferation from polycythaemia vera

    European Journal of Clinical Investigation

    Volume 38, Issue 8, August 2008, Pages: 578–584, M. Wappl, E. Jaeger, B. Streubel, H. Gisslinger, I. Schwarzinger, P. Valent and L. Oehler

    Version of Record online : 17 JUL 2008, DOI: 10.1111/j.1365-2362.2008.01982.x

  11. You have free access to this content
    Dasatinib combined with docetaxel for castration-resistant prostate cancer

    Cancer

    Volume 118, Issue 1, 1 January 2012, Pages: 63–71, John C. Araujo, Paul Mathew, Andrew J. Armstrong, Edward L. Braud, Edwin Posadas, Mathew Lonberg, Gary E. Gallick, Géralyn C. Trudel, Prashni Paliwal, Shruti Agrawal and Christopher J. Logothetis

    Version of Record online : 4 MAR 2011, DOI: 10.1002/cncr.26204

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    Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro-survival microenvironmental signals

    British Journal of Haematology

    Volume 153, Issue 2, April 2011, Pages: 199–211, Alison M. MCCaig, Emilio Cosimo, Michael T. Leach and Alison M. Michie

    Version of Record online : 24 FEB 2011, DOI: 10.1111/j.1365-2141.2010.08507.x

  13. You have free access to this content
    Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors

    Cancer

    Volume 116, Issue 6, 15 March 2010, Pages: 1582–1591, Faye M. Johnson, Shruti Agrawal, Howard Burris, Lee Rosen, Navneet Dhillon, David Hong, Anne Blackwood-Chirchir, Feng R. Luo, Oumar Sy, Sanjeev Kaul and Alberto A. Chiappori

    Version of Record online : 27 JAN 2010, DOI: 10.1002/cncr.24927

  14. Dasatinib in chronic myeloid leukemia: A limited Indian experience

    Asia-Pacific Journal of Clinical Oncology

    Volume 8, Issue 4, December 2012, Pages: 375–379, Atul SHARMA, Ankur BAHL, Vinod RAINA, Lalit KUMAR and Ritu GUPTA

    Version of Record online : 6 JUL 2012, DOI: 10.1111/j.1743-7563.2012.01557.x

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    Ingredients in Fruit Juices Interact with Dasatinib Through Inhibition of BCRP: A New Mechanism of Beverage–Drug Interaction

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 1, January 2015, Pages: 266–275, Brett Fleisher, Jesse Unum, Jie Shao and Guohua An

    Version of Record online : 21 NOV 2014, DOI: 10.1002/jps.24289

  16. The impact of dasatinib on pregnancy outcomes

    American Journal of Hematology

    Volume 90, Issue 12, December 2015, Pages: 1111–1115, Jorge E. Cortes, Elisabetta Abruzzese, Ekaterina Chelysheva, Mausumee Guha, Nicola Wallis and Jane F. Apperley

    Version of Record online : 12 OCT 2015, DOI: 10.1002/ajh.24186

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    Practical management of patients with chronic myeloid leukemia

    Cancer

    Volume 117, Issue 19, 1 October 2011, Pages: 4343–4354, Francisco Cervantes and Michael Mauro

    Version of Record online : 16 MAR 2011, DOI: 10.1002/cncr.26062

  18. You have full text access to this OnlineOpen article
    Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006)

    European Journal of Haematology

    Volume 94, Issue 3, March 2015, Pages: 243–250, Henrik Hjorth-Hansen, Leif Stenke, Stina Söderlund, Arta Dreimane, Hans Ehrencrona, Tobias Gedde-Dahl, Bjørn Tore Gjertsen, Martin Höglund, Perttu Koskenvesa, Kourosh Lotfi, Waleed Majeed, Berit Markevärn, Lotta Ohm, Ulla Olsson-Strömberg, Kari Remes, Merja Suominen, Bengt Simonsson, Kimmo Porkka, Satu Mustjoki, Johan Richter and for the Nordic CML Study Group (NCMLSG)

    Version of Record online : 13 SEP 2014, DOI: 10.1111/ejh.12423

  19. Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily

    European Journal of Clinical Investigation

    Volume 39, Issue 12, December 2009, Pages: 1098–1109, C. Sillaber, H. Herrmann, K. Bennett, U. Rix, C. Baumgartner, A. Böhm, S. Herndlhofer, E. Tschachler, G. Superti-Furga, U. Jäger and P. Valent

    Version of Record online : 9 SEP 2009, DOI: 10.1111/j.1365-2362.2009.02206.x

  20. You have free access to this content
    Dasatinib induces autophagic cell death in human ovarian cancer

    Cancer

    Volume 116, Issue 21, 1 November 2010, Pages: 4980–4990, Xiao-Feng Le, Weiqun Mao, Zhen Lu, Bing Z. Carter and Robert C. Bast Jr

    Version of Record online : 13 JUL 2010, DOI: 10.1002/cncr.25426