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There are 23348 results for: content related to: Romidepsin ( FK 228) and its analogs directly inhibit phosphatidylinositol 3-kinase activity and potently induce apoptosis as histone deacetylase/phosphatidylinositol 3-kinase dual inhibitors

  1. You have full text access to this OnlineOpen article
    Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors

    Cancer Science

    Volume 106, Issue 2, February 2015, Pages: 208–215, Ken Saijo, Jin Imamura, Koichi Narita, Akifumi Oda, Hideki Shimodaira, Tadashi Katoh and Chikashi Ishioka

    Version of Record online : 28 JAN 2015, DOI: 10.1111/cas.12585

  2. You have full text access to this OnlineOpen article
    Class I histone deacetylase inhibitors inhibit the retention of BRCA1 and 53BP1 at the site of DNA damage

    Cancer Science

    Volume 106, Issue 8, August 2015, Pages: 1050–1056, Takayo Fukuda, Wenwen Wu, Maiko Okada, Ichiro Maeda, Yasuyuki Kojima, Ryosuke Hayami, Yasuo Miyoshi, Ko-ichiro Tsugawa and Tomohiko Ohta

    Version of Record online : 14 JUL 2015, DOI: 10.1111/cas.12717

  3. You have full text access to this Open Access content
    In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi-scid/scid Mice

    Japanese Journal of Cancer Research

    Volume 92, Issue 5, May 2001, Pages: 529–536, Hiroshi Kosugi, Masafumi Ito, Yukiya Yamamoto, Masayuki Towatari, Mamoru Ito, Ryuzo Ueda, Hidehiko Saito and Tomoki Naoe

    Version of Record online : 22 AUG 2005, DOI: 10.1111/j.1349-7006.2001.tb01126.x

  4. You have full text access to this Open Access content
    Apoptotic Cytotoxic Effects of a Histone Deacetylase Inhibitor, FK228, on Malignant Lymphoid Cells

    Japanese Journal of Cancer Research

    Volume 91, Issue 11, November 2000, Pages: 1154–1160, Makoto Murata, Masayuki Towatari, Hiroshi Kosugi, Mitsune Tanimoto, Ryuzo Ueda, Hidehiko Saito and Tomoki Naoe

    Version of Record online : 23 AUG 2005, DOI: 10.1111/j.1349-7006.2000.tb00899.x

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    Histone deacetylase inhibitors FK228, N-(2-aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)amino- methyl]benzamide and m-carboxycinnamic acid bis-hydroxamide augment radiation-induced cell death in gastrointestinal adenocarcinoma cells

    International Journal of Cancer

    Volume 110, Issue 2, 10 June 2004, Pages: 301–308, Yubin Zhang, Masaaki Adachi, Xudong Zhao, Rina Kawamura and Kohzoh Imai

    Version of Record online : 19 FEB 2004, DOI: 10.1002/ijc.20117

  6. Oncogenic H-Ras, FK228, and exogenous H2O2 cooperatively activated the erk pathway in selective induction of human urinary bladder cancer j82 cell death

    Molecular Carcinogenesis

    Volume 50, Issue 3, March 2011, Pages: 215–219, Shambhunath Choudhary, Kwo-Kwang Abraham Wang and Hwa-Chain Robert Wang

    Version of Record online : 28 DEC 2010, DOI: 10.1002/mc.20708

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    Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

    International Journal of Cancer

    Volume 97, Issue 3, 20 January 2002, Pages: 290–296, Ho Jeong Kwon, Myoung Sook Kim, Min Jung Kim, Hidenori Nakajima and Kyu-Won Kim

    Version of Record online : 9 OCT 2001, DOI: 10.1002/ijc.1602

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    Pleiotropic role of histone deacetylases in the regulation of human adult erythropoiesis

    British Journal of Haematology

    Volume 135, Issue 2, October 2006, Pages: 242–253, Kentaro Yamamura, Kohshi Ohishi, Naoyuki Katayama, Zhaocai Yu, Keizo Kato, Masahiro Masuya, Atsushi Fujieda, Yuka Sugimoto, Eri Miyata, Tetsunori Shibasaki, Yuji Heike, Yoichi Takaue and Hiroshi Shiku

    Version of Record online : 24 AUG 2006, DOI: 10.1111/j.1365-2141.2006.06275.x

    Corrected by:

    Erratum

    Vol. 136, Issue 1, 175–176, Version of Record online: 25 OCT 2006

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    Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation

    International Journal of Cancer

    Volume 124, Issue 1, 1 January 2009, Pages: 55–67, Motonobu Watanabe, Souichi Adachi, Hiroshi Matsubara, Tsuyoshi Imai, Yoshihiro Yui, Yasuhiro Mizushima, Yoshimi Hiraumi, Ken-ichiro Watanabe, Yuri Kamitsuji, Shin-ya Toyokuni, Hajime Hosoi, Toru Sugimoto, Junya Toguchida and Tatsutoshi Nakahata

    Version of Record online : 26 SEP 2008, DOI: 10.1002/ijc.23897

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    Involvement of P-glycoprotein and MRP1 in resistance to cyclic tetrapeptide subfamily of histone deacetylase inhibitors in the drug-resistant osteosarcoma and Ewing's sarcoma cells

    International Journal of Cancer

    Volume 118, Issue 1, 1 January 2006, Pages: 90–97, Takamitsu Okada, Kazuhiro Tanaka, Fumihiko Nakatani, Riku Sakimura, Tomoya Matsunobu, Xu Li, Masuo Hanada, Tomoyuki Nakamura, Yoshinao Oda, Masazumi Tsuneyoshi and Yukihide Iwamoto

    Version of Record online : 27 JUL 2005, DOI: 10.1002/ijc.21297

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    Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21WAF1/Cip1 expression

    Arthritis & Rheumatism

    Volume 50, Issue 10, October 2004, Pages: 3365–3376, Keiichiro Nishida, Takamitsu Komiyama, Shin-ichi Miyazawa, Zheng-Nan Shen, Takayuki Furumatsu, Hideyuki Doi, Aki Yoshida, Jiro Yamana, Masahiro Yamamura, Yoshihumi Ninomiya, Hajime Inoue and Hiroshi Asahara

    Version of Record online : 8 OCT 2004, DOI: 10.1002/art.20709

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    Antitumor effects of histone deacetylase inhibitor on Ewing's family tumors

    International Journal of Cancer

    Volume 116, Issue 5, 20 September 2005, Pages: 784–792, Riku Sakimura, Kazuhiro Tanaka, Fumihiko Nakatani, Tomoya Matsunobu, Xu Li, Masuo Hanada, Takamitsu Okada, Tomoyuki Nakamura, Yoshihiro Matsumoto and Yukihide Iwamoto

    Version of Record online : 22 APR 2005, DOI: 10.1002/ijc.21069

  13. The Histone Deacetylase Inhibitor FK228 Distinctly Sensitizes the Human Leukemia Cells to Retinoic Acid-Induced Differentiation

    Annals of the New York Academy of Sciences

    Volume 1091, Issue 1, December 2006, Pages: 368–384, JURATE SAVICKIENE, GRAZINA TREIGYTE, VERONIKA BORUTINSKAITE, RUTA NAVAKAUSKIENE and KARL-ERIC MAGNUSSON

    Version of Record online : 26 JAN 2007, DOI: 10.1196/annals.1378.081

  14. You have full text access to this Open Access content
    Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide

    Cancer Science

    Volume 101, Issue 10, October 2010, Pages: 2214–2219, Hideki Mizutani, Yusuke Hiraku, Saeko Tada-Oikawa, Mariko Murata, Kenji Ikemura, Takuya Iwamoto, Yoshiyuki Kagawa, Masahiro Okuda and Shosuke Kawanishi

    Version of Record online : 11 JUN 2010, DOI: 10.1111/j.1349-7006.2010.01645.x

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    The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy

    International Journal of Cancer

    Volume 120, Issue 8, 15 April 2007, Pages: 1795–1802, Jose A. Karam, Jinhai Fan, Jennifer Stanfield, Edmond Richer, Elie A. Benaim, Eugene Frenkel, Peter Antich, Arthur I. Sagalowsky, Ralph P. Mason and Jer-Tsong Hsieh

    Version of Record online : 17 JAN 2007, DOI: 10.1002/ijc.22405

  16. The Bicyclic Depsipeptide Family of Histone Deacetylase Inhibitors

    Chemical Biology: From Small Molecules to Systems Biology and Drug Design, Volume 1-3

    Paul A. Townsend, Simon J. Crabb, Sean M. Davidson, Peter W. M. Johnson, Graham Packham, Arasu Ganesan, Pages: 693–720, 2008

    Published Online : 21 APR 2008, DOI: 10.1002/9783527619375.ch12

  17. Identification of thiols and glutathione conjugates of depsipeptide FK228 (FR901228), a novel histone protein deacetylase inhibitor, in the blood

    Rapid Communications in Mass Spectrometry

    Volume 17, Issue 8, 30 April 2003, Pages: 757–766, Jim J. Xiao, John Byrd, Guido Marcucci, Michael Grever and Kenneth K. Chan

    Version of Record online : 4 MAR 2003, DOI: 10.1002/rcm.976

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    Histone deacetylase inhibitor FK228 is a potent inducer of human fetal hemoglobin

    American Journal of Hematology

    Volume 81, Issue 12, December 2006, Pages: 981–983, Hua Cao and George Stamatoyannopoulos

    Version of Record online : 3 AUG 2006, DOI: 10.1002/ajh.20676

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    Depsipeptide and roxithromycin induce apoptosis of lymphoma cells by blocking extracellular signal-regulated kinase activation

    The Journal of Dermatology

    Volume 41, Issue 1, January 2014, Pages: 57–62, Sohshi Morimura, Makoto Sugaya, Hiromichi Kai, Tomomitsu Miyagaki, Yoshihide Asano, Yayoi Tada, Takafumi Kadono, Takashi Murakami and Sinichi Sato

    Version of Record online : 18 JAN 2014, DOI: 10.1111/1346-8138.12351

  20. You have full text access to this OnlineOpen article
    Antitumor activity and pharmacologic characterization of the depsipeptide analog as a novel histone deacetylase/ phosphatidylinositol 3-kinase dual inhibitor

    Cancer Science

    Volume 108, Issue 7, July 2017, Pages: 1469–1475, Ken Saijo, Hiroo Imai, Sonoko Chikamatsu, Koichi Narita, Tadashi Katoh and Chikashi Ishioka

    Version of Record online : 19 MAY 2017, DOI: 10.1111/cas.13255