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There are 39392 results for: content related to: Romidepsin (FK228) and its analogs directly inhibit PI3 kinase activity and induce apoptosis. An enlarged picture around the ligand is shown. A ball and stick model shows the reduced Romidepsin in the PI3 kinase ribbon and line drawing. See also Saijo, K., et al.

  1. You have full text access to this OnlineOpen article
    Biochemical, biological and structural properties of romidepsin (FK228) and its analogs as novel HDAC/PI3K dual inhibitors

    Cancer Science

    Volume 106, Issue 2, February 2015, Pages: 208–215, Ken Saijo, Jin Imamura, Koichi Narita, Akifumi Oda, Hideki Shimodaira, Tadashi Katoh and Chikashi Ishioka

    Version of Record online : 28 JAN 2015, DOI: 10.1111/cas.12585

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    Romidepsin (FK228) and its analogs directly inhibit phosphatidylinositol 3-kinase activity and potently induce apoptosis as histone deacetylase/phosphatidylinositol 3-kinase dual inhibitors

    Cancer Science

    Volume 103, Issue 11, November 2012, Pages: 1994–2001, Ken Saijo, Tadashi Katoh, Hideki Shimodaira, Akifumi Oda, Ohgi Takahashi and Chikashi Ishioka

    Version of Record online : 12 OCT 2012, DOI: 10.1111/cas.12002

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    Electrocardiographic effects of class 1 selective histone deacetylase inhibitor romidepsin

    Cancer Medicine

    Volume 4, Issue 8, August 2015, Pages: 1178–1185, Philip T. Sager, Barbara Balser, Julie Wolfson, Jean Nichols, Richard Pilot, Suzanne Jones and Howard A. Burris

    Version of Record online : 27 APR 2015, DOI: 10.1002/cam4.467

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    Evaluation of CYP3A-mediated drug–drug interactions with romidepsin in patients with advanced cancer

    The Journal of Clinical Pharmacology

    Volume 55, Issue 12, December 2015, Pages: 1378–1385, Eric Laille, Manish Patel, Suzanne F. Jones, Howard A. Burris III, Jeffrey Infante, Charlotte Lemech, Liangang Liu and Hendrik-Tobias Arkenau

    Version of Record online : 29 JUL 2015, DOI: 10.1002/jcph.560

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    Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir

    International Journal of Cancer

    Volume 138, Issue 1, 1 January 2016, Pages: 125–136, Kwai Fung Hui, Arthur Kwok Leung Cheung, Chung King Choi, Po Ling Yeung, Jaap M. Middeldorp, Maria Li Lung, Sai Wah Tsao and Alan Kwok Shing Chiang

    Version of Record online : 11 AUG 2015, DOI: 10.1002/ijc.29698

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    Sequential treatment with 5-aza-2′-deoxycytidine and deacetylase inhibitors reactivates HIV-1

    EMBO Molecular Medicine

    Volume 8, Issue 2, February 2016, Pages: 117–138, Sophie Bouchat, Nadège Delacourt, Anna Kula, Gilles Darcis, Benoit Van Driessche, Francis Corazza, Jean-Stéphane Gatot, Adeline Melard, Caroline Vanhulle, Kabamba Kabeya, Marion Pardons, Véronique Avettand-Fenoel, Nathan Clumeck, Stéphane De Wit, Olivier Rohr, Christine Rouzioux and Carine Van Lint

    Version of Record online : 17 DEC 2015, DOI: 10.15252/emmm.201505557

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    Romidepsin in peripheral and cutaneous T-cell lymphoma: mechanistic implications from clinical and correlative data

    British Journal of Haematology

    Volume 170, Issue 1, July 2015, Pages: 96–109, Susan E. Bates, Robin Eisch, Alexander Ling, Douglas Rosing, Maria Turner, Stefania Pittaluga, H. Miles Prince, Mark H. Kirschbaum, Steven L. Allen, Jasmine Zain, Larisa J. Geskin, David Joske, Leslie Popplewell, Edward W. Cowen, Elaine S. Jaffe, Jean Nichols, Sally Kennedy, Seth M. Steinberg, David J. Liewehr, Louise C. Showe, Caryn Steakley, John Wright, Tito Fojo, Thomas Litman and Richard L. Piekarz

    Version of Record online : 19 APR 2015, DOI: 10.1111/bjh.13400

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    Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide

    Cancer Science

    Volume 101, Issue 10, October 2010, Pages: 2214–2219, Hideki Mizutani, Yusuke Hiraku, Saeko Tada-Oikawa, Mariko Murata, Kenji Ikemura, Takuya Iwamoto, Yoshiyuki Kagawa, Masahiro Okuda and Shosuke Kawanishi

    Version of Record online : 11 JUN 2010, DOI: 10.1111/j.1349-7006.2010.01645.x

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    The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients

    American Journal of Hematology

    Volume 87, Issue 4, April 2012, Pages: 354–360, Michael J. Kelly-Sell, Youn H. Kim, Suzanne Straus, Bernice Benoit, Cameron Harrison, Katherine Sutherland, Randall Armstrong, Wen-Kai Weng, Louise C. Showe, Maria Wysocka and Alain H. Rook

    Version of Record online : 24 FEB 2012, DOI: 10.1002/ajh.23112

  10. Low-dose electron beam radiation and romidepsin therapy for symptomatic cutaneous T-cell lymphoma lesions

    British Journal of Dermatology

    Volume 167, Issue 1, July 2012, Pages: 194–197, O.E. Akilov, C. Grant, R. Frye, S. Bates, R. Piekarz and L.J. Geskin

    Version of Record online : 28 JUN 2012, DOI: 10.1111/j.1365-2133.2012.10905.x

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    Combination of proteasome and class I HDAC inhibitors induces apoptosis of NPC cells through an HDAC6-independent ER stress-induced mechanism

    International Journal of Cancer

    Volume 135, Issue 12, 15 December 2014, Pages: 2950–2961, Kwai Fung Hui and Alan K.S. Chiang

    Version of Record online : 5 MAY 2014, DOI: 10.1002/ijc.28924

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    Multi-walled carbon nanotubes induce visceral mesothelial proliferation in rats. An enlarged picture around the ligand is shown. Scanning electron microscope observation demonstrates the existence of the multi-walled carbon nanotube fibers in the cell pellets of the pleural cavity lavages.

    Cancer Science

    Volume 103, Issue 12, December 2012, Page: December cover, Jiegou Xu, Mitsuru Futakuchi, Hideo Shimizu, David B. Alexander, Kazuyoshi Yanagihara, Katsumi Fukamachi, Masumi Suzui, Jun Kanno, Akihiko Hirose, Akio Ogata, Yoshimitsu Sakamoto, Dai Nakae, Toyonori Omori and Hiroyuki Tsuda

    Version of Record online : 5 DEC 2012, DOI: 10.1111/cas.12035

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    Preliminary Page

    Cancer Science

    Volume 103, Issue 11, November 2012, Pages: i–ii,

    Version of Record online : 29 OCT 2012, DOI: 10.1111/j.1349-7006.2012.02077.x

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    Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin

    Molecular Oncology

    Volume 8, Issue 8, December 2014, Pages: 1379–1392, Victoria L. Luchenko, Thomas Litman, Arup R. Chakraborty, Aaron Heffner, Christopher Devor, Julia Wilkerson, Wilfred Stein, Robert W. Robey, Lois Bangiolo, David Levens, Susan E. Bates

    Version of Record online : 28 MAY 2014, DOI: 10.1016/j.molonc.2014.05.001

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    Romidepsin (FK228) and its analogs as HDAC/PI3K dual inhibitors. A molecular surface structure around FK-A11 in the ATP-binding pocket

    Cancer Science

    Volume 106, Issue 2, February 2015, Page: February cover, Ken Saijo, Jin Imamura, Koichi Narita, Akifumi Oda, Hideki Shimodaira, Tadashi Katoh and Chikashi Ishioka

    Version of Record online : 20 FEB 2015, DOI: 10.1111/cas.12607

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    Natural and Synthetic Macrocyclic Inhibitors of the Histone Deacetylase Enzymes

    ChemBioChem

    Volume 18, Issue 1, January 3, 2017, Pages: 5–49, Dr. Alex R. Maolanon, Helle M. E. Kristensen, Prof. Dr. Luke J. Leman, Prof. Dr. M. Reza Ghadiri and Prof. Dr. Christian A. Olsen

    Version of Record online : 8 DEC 2016, DOI: 10.1002/cbic.201600519

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    The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expression in cutaneous T-cell lymphoma cells

    British Journal of Pharmacology

    Volume 162, Issue 7, April 2011, Pages: 1590–1602, CE Tiffon, JE Adams, L van der Fits, S Wen, PA Townsend, A Ganesan, E Hodges, MH Vermeer and G Packham

    Version of Record online : 4 MAR 2011, DOI: 10.1111/j.1476-5381.2010.01188.x

  18. Natural Products as Zinc-Dependent Histone Deacetylase Inhibitors

    ChemMedChem

    Volume 10, Issue 3, March 2015, Pages: 441–450, Shuai Tan and Prof. Dr. Zhao-Peng Liu

    Version of Record online : 7 JAN 2015, DOI: 10.1002/cmdc.201402460

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    Phase 2 trial of the histone deacetylase inhibitor romidepsin for the treatment of refractory multiple myeloma

    Cancer

    Volume 117, Issue 2, 15 January 2011, Pages: 336–342, Ruben Niesvizky, Scott Ely, Tomer Mark, Sangeeta Aggarwal, Janice L Gabrilove, John J. Wright, Selina Chen-Kiang and Joseph A Sparano

    Version of Record online : 22 SEP 2010, DOI: 10.1002/cncr.25584

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    The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo

    Journal of Cellular and Molecular Medicine

    Volume 21, Issue 7, July 2017, Pages: 1300–1314, Sina Jostes, Daniel Nettersheim, Martin Fellermeyer, Simon Schneider, François Hafezi, Friedemann Honecker, Valerie Schumacher, Matthias Geyer, Glen Kristiansen and Hubert Schorle

    Version of Record online : 27 DEC 2016, DOI: 10.1111/jcmm.13059