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There are 19560 results for: content related to: Anti-angiogenic and anti-tumor effects of TAK -593, a potent and selective inhibitor of vascular endothelial growth factor and platelet-derived growth factor receptor tyrosine kinase

  1. You have free access to this content
    Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593* in esophageal cancer

    International Journal of Cancer

    Volume 129, Issue 9, 1 November 2011, Pages: 2134–2146, Tetsuo Ito, Fumiaki Sato, Takatsugu Kan, Yulan Cheng, Stefan David, Rachana Agarwal, Bogdan C. Paun, Zhe Jin, Alexandru V. Olaru, James P. Hamilton, Florin M. Selaru, Jian Yang, Nobutoshi Matsumura, Kazuharu Shimizu, John M. Abraham, Yutaka Shimada, Yuriko Mori and Stephen J. Meltzer

    Article first published online : 11 MAR 2011, DOI: 10.1002/ijc.25874

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    Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

    British Journal of Pharmacology

    Volume 157, Issue 7, August 2009, Pages: 1250–1262, K Takashima, N Matsunaga, M Yoshimatsu, K Hazeki, T Kaisho, M Uekata, O Hazeki, S Akira, Y Iizawa and M Ii

    Article first published online : 25 JUN 2009, DOI: 10.1111/j.1476-5381.2009.00297.x

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    A Salmonella SipB-derived polypeptide blocks the ‘trigger’ mechanism of bacterial entry into eukaryotic cells

    Molecular Microbiology

    Volume 45, Issue 6, September 2002, Pages: 1715–1727, Richard D. Hayward, Peter J. Hume, Emma J. McGhie and Vassilis Koronakis

    Article first published online : 27 SEP 2002, DOI: 10.1046/j.1365-2958.2002.03124.x

  4. Brief Report: Takayasu Arteritis and Ulcerative Colitis: High Rate of Co-Occurrence and Genetic Overlap

    Arthritis & Rheumatology

    Volume 67, Issue 8, August 2015, Pages: 2226–2232, Chikashi Terao, Takayoshi Matsumura, Hajime Yoshifuji, Yohei Kirino, Yasuhiro Maejima, Yoshikazu Nakaoka, Meiko Takahashi, Eisuke Amiya, Natsuko Tamura, Toshiki Nakajima, Tomoki Origuchi, Tetsuya Horita, Mitsuru Matsukura, Yuta Kochi, Akiyoshi Ogimoto, Motohisa Yamamoto, Hiroki Takahashi, Shingo Nakayamada, Kazuyoshi Saito, Yoko Wada, Ichiei Narita, Yasushi Kawaguchi, Hisashi Yamanaka, Koichiro Ohmura, Tatsuya Atsumi, Kazuo Tanemoto, Tetsuro Miyata, Masataka Kuwana, Issei Komuro, Yasuharu Tabara, Atsuhisa Ueda, Mitsuaki Isobe, Tsuneyo Mimori and Fumihiko Matsuda

    Article first published online : 28 JUL 2015, DOI: 10.1002/art.39157

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    Double-blind, randomized, placebo-controlled study of safety, tolerability, pharmacokinetics and pharmacodynamics of TAK-683, an investigational metastin analogue in healthy men

    British Journal of Clinical Pharmacology

    Volume 75, Issue 2, February 2013, Pages: 381–391, Graham Scott, Irfan Ahmad, Katy Howard, David MacLean, Cristina Oliva, Steve Warrington, Darren Wilbraham and Paul Worthington

    Article first published online : 10 JAN 2013, DOI: 10.1111/j.1365-2125.2012.04385.x

  6. Chemical reactivity of ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242) in vitro

    Biopharmaceutics & Drug Disposition

    Volume 32, Issue 7, October 2011, Pages: 408–425, Fumihiro Jinno, Tomoki Yoneyama, Akio Morohashi, Takahiro Kondo and Satoru Asahi

    Article first published online : 2 SEP 2011, DOI: 10.1002/bdd.769

  7. A Multiple-Ascending-Dose Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of a Novel GPR40 Agonist, TAK-875, in Subjects With Type 2 Diabetes

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 1, July 2012, Pages: 29–39, E Leifke, H Naik, J Wu, P Viswanathan, D DeManno, M Kipnes and M Vakilynejad

    Article first published online : 6 JUN 2012, DOI: 10.1038/clpt.2012.43

  8. Takayasu Arteritis and Pregnancy

    Arthritis & Rheumatology

    Volume 67, Issue 12, December 2015, Pages: 3262–3269, C. Comarmond, T. Mirault, L. Biard, J. Nizard, M. Lambert, B. Wechsler, E. Hachulla, L. Chiche, F. Koskas, J. Gaudric, P. Cluzel, E. Messas, M. Resche-Rigon, J. C. Piette, P. Cacoub, D. Saadoun and for the French Takayasu Network

    Article first published online : 25 NOV 2015, DOI: 10.1002/art.39335

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    In This Issue

    Cancer Science

    Volume 104, Issue 4, April 2013, Page: iii,

    Article first published online : 8 MAR 2013, DOI: 10.1111/cas.12114

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    Recent advances in Takayasu arteritis

    International Journal of Rheumatic Diseases

    Volume 17, Issue 3, March 2014, Pages: 238–247, Chikashi Terao, Hajime Yoshifuji and Tsuneyo Mimori

    Article first published online : 18 FEB 2014, DOI: 10.1111/1756-185X.12309

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    TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats

    British Journal of Pharmacology

    Volume 170, Issue 3, October 2013, Pages: 568–580, R Ito, Y Tsujihata, K Matsuda-Nagasumi, I Mori, N Negoro and K Takeuchi

    Article first published online : 17 SEP 2013, DOI: 10.1111/bph.12297

  12. Retrospective analysis of 95 patients with large vessel vasculitis: a single center experience

    International Journal of Rheumatic Diseases

    Volume 19, Issue 1, January 2016, Pages: 87–94, Masaaki Yoshida, Ryu Watanabe, Tomonori Ishii, Tomoaki Machiyama, Kanae Akita, Yoko Fujita, Yuko Shirota, Koichiro Sugimura, Hiroshi Fujii, Hiroaki Shimokawa and Hideo Harigae

    Article first published online : 7 OCT 2015, DOI: 10.1111/1756-185X.12777

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    Mitogenic Signaling via Endogenous κ-Opioid Receptors in C6 Glioma Cells

    Journal of Neurochemistry

    Volume 74, Issue 2, February 2000, Pages: 564–573, Laura M. Bohn, Mariana M. Belcheva and Carmine J. Coscia

    Article first published online : 25 DEC 2001, DOI: 10.1046/j.1471-4159.2000.740564.x

  14. Th1 and Th17 Cytokines Drive Inflammation in Takayasu Arteritis

    Arthritis & Rheumatology

    Volume 67, Issue 5, May 2015, Pages: 1353–1360, D. Saadoun, M. Garrido, C. Comarmond, A. C. Desbois, F. Domont, L. Savey, B. Terrier, G. Geri, M. Rosenzwajg, D. Klatzmann, P. Fourret, P. Cluzel, L. Chiche, J. Gaudric, F. Koskas and P. Cacoub

    Article first published online : 27 APR 2015, DOI: 10.1002/art.39037

  15. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Properties of the GPR40 Agonist TAK-875: Results From a Double-Blind, Placebo-Controlled Single Oral Dose Rising Study in Healthy Volunteers

    The Journal of Clinical Pharmacology

    Volume 52, Issue 7, July 2012, Pages: 1007–1016, Dr Himanshu Naik, Dr Majid Vakilynejad, Dr Jingtao Wu, Dr Prabhakar Viswanathan, Dr Nobuhito Dote, Dr Tomoaki Higuchi and Dr Eckhard Leifke

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270011409230

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    Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats

    British Journal of Pharmacology

    Volume 145, Issue 8, August 2005, Pages: 1035–1044, Izzettin Hatip-Al-Khatib, Katsunori Iwasaki, Yoshitaka Yoshimitsu, Takashi Arai, Nobuaki Egashira, Kenichi Mishima, Tomoaki Ikeda and Michihiro Fujiwara

    Article first published online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0706288

  17. Sustained-release microcapsules of a bone formation stimulant, TAK-778, for local injection into a fracture site

    Journal of Pharmaceutical Sciences

    Volume 90, Issue 12, December 2001, Pages: 2121–2130, Tetsuo Hoshino, Kazuhiro Saito, Hiroya Muranishi, Takashi Sohda and Yasuaki Ogawa

    Article first published online : 26 NOV 2001, DOI: 10.1002/jps.1163

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    A non-peptide CCR5 antagonist inhibits collagen-induced arthritis by modulating T cell migration without affecting anti-collagen T cell responses

    European Journal of Immunology

    Volume 32, Issue 8, August 2002, Pages: 2124–2132, Yi-Fu Yang, Takao Mukai, Ping Gao, Nobuya Yamaguchi, Shiro Ono, Hiroshi Iwaki, Satoshi Obika, Takeshi Imanishi, Takahiro Tsujimura, Toshiyuki Hamaoka and Hiromi Fujiwara

    Article first published online : 22 JUL 2002, DOI: 10.1002/1521-4141(200208)32:8<2124::AID-IMMU2124>3.0.CO;2-S

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    Lipid-lowering properties of TAK-475, a squalene synthase inhibitor, in vivo and in vitro

    British Journal of Pharmacology

    Volume 139, Issue 5, July 2003, Pages: 911–918, Tomoyuki Nishimoto, Yuichiro Amano, Ryuichi Tozawa, Eiichiro Ishikawa, Yoshimi Imura, Hidefumi Yukimasa and Yasuo Sugiyama

    Article first published online : 30 JAN 2009, DOI: 10.1038/sj.bjp.0705332

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    Author Index

    Hepatology

    Volume 60, Issue S1, October 2014, Pages: 1205A–1254A,

    Article first published online : 1 OCT 2014, DOI: 10.1002/hep.27417