Search Results

There are 15441 results for: content related to: K lotho suppresses tumor progression via inhibiting PI 3 K / A kt/ GSK 3β/Snail signaling in renal cell carcinoma

  1. Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility

    Pigment Cell & Melanoma Research

    Volume 24, Issue 1, February 2011, Pages: 175–186, Tura C. Camilli, Mai Xu, Michael P. O’Connell, Bonnie Chien, Brittany P. Frank, Sarah Subaran, Fred E. Indig, Patrice J. Morin, Stephen M. Hewitt and Ashani T. Weeraratna

    Article first published online : 1 DEC 2010, DOI: 10.1111/j.1755-148X.2010.00792.x

  2. Klotho suppresses renal tubulo-interstitial fibrosis by controlling basic fibroblast growth factor-2 signalling

    The Journal of Pathology

    Volume 234, Issue 4, December 2014, Pages: 560–572, Xu Guan, Ling Nie, Ting He, Ke Yang, Tangli Xiao, Song Wang, Yunjian Huang, Jingbo Zhang, Junping Wang, Kumar Sharma, Youhua Liu and Jinghong Zhao

    Article first published online : 30 SEP 2014, DOI: 10.1002/path.4420

  3. You have full text access to this OnlineOpen article
    FGF23 promotes renal calcium reabsorption through the TRPV5 channel

    The EMBO Journal

    Volume 33, Issue 3, 3 February 2014, Pages: 229–246, Olena Andrukhova, Alina Smorodchenko, Monika Egerbacher, Carmen Streicher, Ute Zeitz, Regina Goetz, Victoria Shalhoub, Moosa Mohammadi, Elena E Pohl, Beate Lanske and Reinhold G Erben

    Article first published online : 17 JAN 2014, DOI: 10.1002/embj.201284188

  4. You have free access to this content
    Understanding the Physical Interactions in the FGF21/FGFR/β-Klotho Complex: Structural Requirements and Implications in FGF21 Signaling

    Chemical Biology & Drug Design

    Volume 79, Issue 4, April 2012, Pages: 398–410, Junming Yie, Wei Wang, Liying Deng, Lei-Ting Tam, Jennitte Stevens, Michelle M. Chen, Yang Li, Jing Xu, Richard Lindberg, Randy Hecht, Murielle Véniant, Ching Chen and Minghan Wang

    Article first published online : 1 FEB 2012, DOI: 10.1111/j.1747-0285.2012.01325.x

  5. You have free access to this content
    Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice

    The Journal of Physiology

    Volume 588, Issue 16, August 2010, Pages: 3101–3117, Ferenc Izbeki, David T. Asuzu, Andrea Lorincz, Michael R. Bardsley, Laura N. Popko, Kyoung Moo Choi, David L. Young, Yujiro Hayashi, David R. Linden, Makoto Kuro-o, Gianrico Farrugia and Tamas Ordog

    Article first published online : 13 AUG 2010, DOI: 10.1113/jphysiol.2010.191023

  6. You have free access to this content
    Generalized neuromuscular hypoplasia, reduced smooth muscle myosin and altered gut motility in the klotho model of premature aging

    Neurogastroenterology & Motility

    Volume 23, Issue 7, July 2011, Pages: e309–e323, D. T. Asuzu, Y. Hayashi, F. Izbeki, L. N. Popko, D. L. Young, M. R. Bardsley, A. Lorincz, M. Kuro-o, D. R. Linden, G. Farrugia and T. Ordog

    Article first published online : 24 MAY 2011, DOI: 10.1111/j.1365-2982.2011.01730.x

  7. You have free access to this content
    FGF21 N- and C-termini play different roles in receptor interaction and activation

    FEBS Letters

    Volume 583, Issue 1, January 05, 2009, Pages: 19–24, Junming Yie, Randy Hecht, Jennifer Patel, Jennitte Stevens, Wei Wang, Nessa Hawkins, Shirley Steavenson, Steve Smith, Dwight Winters, Seth Fisher, Ling Cai, Ed Belouski, Ching Chen, Mark L. Michaels, Yue-Sheng Li, Richard Lindberg, Minghan Wang, Murielle Véniant and Jing Xu

    Article first published online : 4 DEC 2008, DOI: 10.1016/j.febslet.2008.11.023

  8. You have free access to this content
    The importance of klotho in phosphate metabolism and kidney disease


    Volume 19, Issue 8, August 2014, Pages: 439–449, Sven-Jean Tan, Edward R Smith, Tim D Hewitson, Stephen G Holt and Nigel D Toussaint

    Article first published online : 25 JUL 2014, DOI: 10.1111/nep.12268

  9. You have free access to this content
    Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway

    FEBS Letters

    Volume 580, Issue 24, October 16, 2006, Pages: 5753–5758, Rita Machado de Oliveira

    Article first published online : 27 SEP 2006, DOI: 10.1016/j.febslet.2006.09.036

  10. You have free access to this content
    Regulation of the Na+/K+ ATPase by Klotho

    FEBS Letters

    Volume 585, Issue 12, June 23, 2011, Pages: 1759–1764, Mentor Sopjani, Ioana Alesutan, Miribane Dërmaku-Sopjani, Shuchen Gu, Christine Zelenak, Carlos Munoz, Ana Velic, Michael Föller, Kevin P. Rosenblatt, Makoto Kuro-o and Florian Lang

    Article first published online : 19 MAY 2011, DOI: 10.1016/j.febslet.2011.05.021

  11. You have free access to this content
    Retinitis Pigmentosa: over-expression of anti-ageing protein Klotho in degenerating photoreceptors

    Journal of Neurochemistry

    Volume 127, Issue 6, December 2013, Pages: 868–879, Pietro Farinelli, Blanca Arango-Gonzalez, Jakob Völkl, Ioana Alesutan, Florian Lang, Eberhart Zrenner, François Paquet-Durand and Per A.R. Ekström

    Article first published online : 22 JUL 2013, DOI: 10.1111/jnc.12353

  12. Long-term sevelamer treatment lowers serum fibroblast growth factor 23 accompanied with increasing serum Klotho levels in chronic haemodialysis patients


    Volume 19, Issue 11, November 2014, Pages: 672–678, Hsin-Hung Lin, Hung-Hsiang Liou, Ming-Shiou Wu, Ching-Yuang Lin and Chiu-Ching Huang

    Article first published online : 12 OCT 2014, DOI: 10.1111/nep.12319

  13. You have full text access to this Open Access content
    Klotho gene delivery suppresses Nox2 expression and attenuates oxidative stress in rat aortic smooth muscle cells via the cAMP-PKA pathway

    Aging Cell

    Volume 11, Issue 3, June 2012, Pages: 410–417, Yuhong Wang, Makoto Kuro-o and Zhongjie Sun

    Article first published online : 22 FEB 2012, DOI: 10.1111/j.1474-9726.2012.00796.x

  14. You have free access to this content
    Glycosylation of fibroblast growth factor receptor 4 is a key regulator of fibroblast growth factor 19–mediated down-regulation of cytochrome P450 7A1


    Volume 52, Issue 2, August 2010, Pages: 656–666, Vassilis Triantis, Eirikur Saeland, Nora Bijl, Ronald P. Oude-Elferink and Peter L. M. Jansen

    Article first published online : 8 APR 2010, DOI: 10.1002/hep.23708

  15. You have free access to this content
    Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane

    FEBS Letters

    Volume 565, Issue 1-3, May 07, 2004, Pages: 143–147, Akihiro Imura, Akiko Iwano, Osamu Tohyama, Yoshihito Tsuji, Kazuhiko Nozaki, Nobuo Hashimoto, Toshihiko Fujimori and Yo-Ichi Nabeshima

    Article first published online : 13 APR 2004, DOI: 10.1016/j.febslet.2004.03.090

  16. Xeno-Klotho Inhibits Parathyroid Hormone Signaling

    Journal of Bone and Mineral Research

    Volume 31, Issue 2, February 2016, Pages: 455–462, Tsuneo Takenaka, Tsutomu Inoue, Takashi Miyazaki, Matsuhiko Hayashi and Hiromichi Suzuki

    Article first published online : 11 SEP 2015, DOI: 10.1002/jbmr.2691

  17. You have full text access to this OnlineOpen article
    Hypothesis: cell signalling influences age-related risk of colorectal cancer

    Journal of Cellular and Molecular Medicine

    Volume 19, Issue 1, January 2015, Pages: 74–81, Michael Bordonaro and Darina L. Lazarova

    Article first published online : 11 NOV 2014, DOI: 10.1111/jcmm.12366

  18. You have free access to this content
    Klotho sensitivity of the hERG channel

    FEBS Letters

    Volume 587, Issue 11, June 05, 2013, Pages: 1663–1668, Carlos Munoz, Tatsiana Pakladok, Ahmad Almilaji, Bernat Elvira, Guiscard Seebohm, Jakob Voelkl, Michael Föller, Ekaterina Shumilina and Florian Lang

    Article first published online : 18 APR 2013, DOI: 10.1016/j.febslet.2013.04.011

  19. You have free access to this content
    Klotho protein deficiency and aging

    Geriatrics & Gerontology International

    Volume 10, Issue s1, July 2010, Pages: S80–S87, Hiroshi Manya, Keiko Akasaka-Manya and Tamao Endo

    Article first published online : 2 JUN 2010, DOI: 10.1111/j.1447-0594.2010.00596.x

  20. Complement Modulation of Anti-Aging Factor Klotho in Ischemia/Reperfusion Injury and Delayed Graft Function

    American Journal of Transplantation

    Volume 16, Issue 1, January 2016, Pages: 325–333, G. Castellano, A. Intini, A. Stasi, C. Divella, M. Gigante, P. Pontrelli, R. Franzin, M. Accetturo, A. Zito, M. Fiorentino, V. Montinaro, G. Lucarelli, P. Ditonno, M. Battaglia, A. Crovace, F. Staffieri, B. Oortwijn, E. van Amersfoort, G. Pertosa, G. Grandaliano and L. Gesualdo

    Article first published online : 17 AUG 2015, DOI: 10.1111/ajt.13415