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There are 6326 results for: content related to: Mechanistic / mammalian target protein of rapamycin signaling in hematopoietic stem cells and leukemia

  1. You have free access to this content
    mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused

    IUBMB Life

    Volume 63, Issue 10, October 2011, Pages: 896–914, Ismael Bracho-Valdés, Paola Moreno-Alvarez, Israel Valencia-Martínez, Evelyn Robles-Molina, Lydia Chávez-Vargas and José Vázquez-Prado

    Version of Record online : 9 SEP 2011, DOI: 10.1002/iub.558

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    The multifaceted role of mTORC1 in the control of lipid metabolism

    EMBO reports

    Volume 14, Issue 3, March 2013, Pages: 242–251, Stéphane J H Ricoult and Brendan D Manning

    Version of Record online : 12 FEB 2012, DOI: 10.1038/embor.2013.5

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    mTOR complex 1: a key player in neuroadaptations induced by drugs of abuse

    Journal of Neurochemistry

    Volume 130, Issue 2, July 2014, Pages: 172–184, Jeremie Neasta, Segev Barak, Sami Ben Hamida and Dorit Ron

    Version of Record online : 19 APR 2014, DOI: 10.1111/jnc.12725

  4. mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging

    Annals of the New York Academy of Sciences

    Volume 1346, Issue 1, June 2015, Pages: 33–44, Andras Perl

    Version of Record online : 23 APR 2015, DOI: 10.1111/nyas.12756

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    Regulation of TOR by small GTPases

    EMBO reports

    Volume 13, Issue 2, February 2012, Pages: 121–128, Raúl V Durán and Michael N Hall

    Version of Record online : 13 JAN 2012, DOI: 10.1038/embor.2011.257

  6. mTOR signaling for biological control and cancer

    Journal of Cellular Physiology

    Volume 228, Issue 8, August 2013, Pages: 1658–1664, Anya Alayev and Marina K. Holz

    Version of Record online : 18 APR 2013, DOI: 10.1002/jcp.24351

  7. mTOR signalling: the molecular interface connecting metabolic stress, aging and cardiovascular diseases

    Obesity Reviews

    Volume 13, Issue S2, December 2012, Pages: 58–68, Z. Yang and X-F. Ming

    Version of Record online : 29 OCT 2012, DOI: 10.1111/j.1467-789X.2012.01038.x

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    Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

    The Journal of Physiology

    Volume 591, Issue 3, February 2013, Pages: 609–625, Fredrick J. Rosario, Yoshikatsu Kanai, Theresa L. Powell and Thomas Jansson

    Version of Record online : 11 JAN 2013, DOI: 10.1113/jphysiol.2012.238014

  9. You have full text access to this OnlineOpen article
    A comprehensive map of the mTOR signaling network

    Molecular Systems Biology

    Volume 6, Issue 1, 2010, Etienne Caron, Samik Ghosh, Yukiko Matsuoka, Dariel Ashton-Beaucage, Marc Therrien, Sébastien Lemieux, Claude Perreault, Philippe P Roux and Hiroaki Kitano

    Version of Record online : 21 DEC 2010, DOI: 10.1038/msb.2010.108

  10. TDP-43 loss of function increases TFEB activity and blocks autophagosome–lysosome fusion

    The EMBO Journal

    Volume 35, Issue 2, 18 January 2016, Pages: 121–142, Qin Xia, Hongfeng Wang, Zongbing Hao, Cheng Fu, Qingsong Hu, Feng Gao, Haigang Ren, Dong Chen, Junhai Han, Zheng Ying and Guanghui Wang

    Version of Record online : 23 DEC 2015, DOI: 10.15252/embj.201591998

  11. Metabolic control of signalling pathways and metabolic auto-regulation

    Biology of the Cell

    Volume 107, Issue 8, August 2015, Pages: 251–272, Doriane Lorendeau, Stefan Christen, Gianmarco Rinaldi and Sarah-Maria Fendt

    Version of Record online : 1 JUN 2015, DOI: 10.1111/boc.201500015

  12. You have full text access to this OnlineOpen article
    Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins

    Aging Cell

    Volume 14, Issue 2, April 2015, Pages: 265–273, Katherine H. Schreiber, Denise Ortiz, Emmeline C. Academia, Arieanna C. Anies, Chen-Yu Liao and Brian K. Kennedy

    Version of Record online : 4 FEB 2015, DOI: 10.1111/acel.12313

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    mTOR regulation of autophagy

    FEBS Letters

    Volume 584, Issue 7, April 02, 2010, Pages: 1287–1295, Chang Hwa Jung, Seung-Hyun Ro, Jing Cao, Neil Michael Otto and Do-Hyung Kim

    Version of Record online : 18 JAN 2010, DOI: 10.1016/j.febslet.2010.01.017

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    The role of mTOR in the adaptation and failure of β-cells in type 2 diabetes

    Diabetes, Obesity and Metabolism

    Volume 10, Issue s4, November 2008, Pages: 157–169, G. Leibowitz, E. Cerasi and M. Ketzinel-Gilad

    Version of Record online : 2 OCT 2008, DOI: 10.1111/j.1463-1326.2008.00952.x

  15. Mechanistic target of rapamycin complex 1 (mTORC1) is an essential mediator of metabolic and mitogenic effects of FGF19 in hepatoma cells

    Hepatology

    Accepted manuscript online: 14 MAY 2016, Zhi Yi Wan, Johann Shane Tian, Hayden Weng Siong Tan, Ai Lee Chow, Arthur Yi Loong Sim, Kenneth Hon Kim Ban and Yun Chau Long

    DOI: 10.1002/hep.28639

  16. Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: Assembly of a multiprotein signaling complex

    Journal of Cellular Biochemistry

    Volume 113, Issue 5, May 2012, Pages: 1488–1500, Uma K. Misra and Salvatore V. Pizzo

    Version of Record online : 15 MAR 2012, DOI: 10.1002/jcb.24018

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    A modelling–experimental approach reveals insulin receptor substrate (IRS)-dependent regulation of adenosine monosphosphate-dependent kinase (AMPK) by insulin

    The FEBS Journal

    Volume 279, Issue 18, September 2012, Pages: 3314–3328, Annika G. Sonntag, Piero Dalle Pezze, Daryl P. Shanley and Kathrin Thedieck

    Version of Record online : 3 MAY 2012, DOI: 10.1111/j.1742-4658.2012.08582.x

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    Therapeutic targeting of the mTOR-signalling pathway in cancer: benefits and limitations

    British Journal of Pharmacology

    Volume 171, Issue 16, August 2014, Pages: 3801–3813, M Moschetta, A Reale, C Marasco, A Vacca and M R Carratù

    Version of Record online : 25 JUL 2014, DOI: 10.1111/bph.12749

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    Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling

    The Journal of Physiology

    Volume 589, Issue 7, April 2011, Pages: 1831–1846, Mitsunori Miyazaki, John J. McCarthy, Mark J. Fedele and Karyn A. Esser

    Version of Record online : 30 MAR 2011, DOI: 10.1113/jphysiol.2011.205658

  20. You have full text access to this OnlineOpen article
    Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne

    Experimental Dermatology

    Volume 22, Issue 5, May 2013, Pages: 311–315, Bodo C. Melnik and Christos C. Zouboulis

    Version of Record online : 25 APR 2013, DOI: 10.1111/exd.12142