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There are 9324 results for: content related to: Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model

  1. Impact of EGFR point mutations on the sensitivity to gefitinib: Insights from comparative structural analyses and molecular dynamics simulations

    Proteins: Structure, Function, and Bioinformatics

    Volume 65, Issue 2, 1 November 2006, Pages: 331–346, Bing Liu, Brandon Bernard and Jian Hui Wu

    Version of Record online : 22 AUG 2006, DOI: 10.1002/prot.21111

  2. You have full text access to this Open Access content
    Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors

    Cancer Science

    Volume 103, Issue 11, November 2012, Pages: 1946–1954, Kunihiko Minakata, Fumiyuki Takahashi, Takeshi Nara, Muneaki Hashimoto, Ken Tajima, Akiko Murakami, Fariz Nurwidya, Suzu Yae, Fumiaki Koizumi, Hiroyuki Moriyama, Kuniaki Seyama, Kazuto Nishio and Kazuhisa Takahashi

    Version of Record online : 14 SEP 2012, DOI: 10.1111/j.1349-7006.2012.02408.x

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    Sensitivity and kinase activity of epidermal growth factor receptor (EGFR) exon 19 and others to EGFR-tyrosine kinase inhibitors

    Cancer Science

    Volume 104, Issue 5, May 2013, Pages: 584–589, Kazuto Furuyama, Taishi Harada, Eiji Iwama, Yoshimasa Shiraishi, Kyoko Okamura, Kayo Ijichi, Akiko Fujii, Keiichi Ota, Shuo Wang, Heyan Li, Koichi Takayama, Giuseppe Giaccone and Yoichi Nakanishi

    Version of Record online : 28 MAR 2013, DOI: 10.1111/cas.12125

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    Cisplatin influences acquisition of resistance to molecular-targeted agents through epithelial–mesenchymal transition-like changes

    Cancer Science

    Volume 104, Issue 7, July 2013, Pages: 904–911, Maki Kurokawa, Nobuyuki Ise, Kazuya Omi, Katsutoshi Goishi and Shigeki Higashiyama

    Version of Record online : 15 MAY 2013, DOI: 10.1111/cas.12171

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    MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib

    Molecular Oncology

    Volume 7, Issue 1, February 2013, Pages: 112–120, Ming-Hung Huang, Jih-Hsiang Lee, Ya-Ju Chang, Hsin-Hui Tsai, Yu-Lin Lin, Anya Maan-Yuh Lin, James Chih-Hsin Yang

    Version of Record online : 13 OCT 2012, DOI: 10.1016/j.molonc.2012.09.002

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    First-line treatment of advanced epidermal growth factor receptor (EGFR) mutation positive non-squamous non-small cell lung cancer

    Intervention Review

    The Cochrane Library

    Janette Greenhalgh, Kerry Dwan, Angela Boland, Victoria Bates, Fabio Vecchio, Yenal Dundar, Pooja Jain and John A Green

    Published Online : 25 MAY 2016, DOI: 10.1002/14651858.CD010383.pub2

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    Peptide nucleic acid–locked nucleic acid polymerase chain reaction clamp-based detection test for gefitinib-refractory T790M epidermal growth factor receptor mutation

    Cancer Science

    Volume 99, Issue 3, March 2008, Pages: 595–600, Hitoshi Miyazawa, Tomoaki Tanaka, Yoshiaki Nagai, Masaru Matsuoka, , Akihisa Sutani, Kiyoshi Udagawa, Jialing Zhang, Takashi Hirama, Yoshitake Murayama, Nobuyuki Koyama, Kenji Ikebuchi, Makoto Nagata, Minoru Kanazawa, Toshihiro Nukiwa, Seiichi Takenoshita, Kunihiko Kobayashi and Koichi Hagiwara

    Version of Record online : 2 JAN 2008, DOI: 10.1111/j.1349-7006.2007.00706.x

  8. You have full text access to this OnlineOpen article
    Enhanced gefitinib-induced repression of the epidermal growth factor receptor pathway by ataxia telangiectasia-mutated kinase inhibition in non-small-cell lung cancer cells

    Cancer Science

    Volume 107, Issue 4, April 2016, Pages: 444–451, Keizo Misumi, Jiying Sun, Aiko Kinomura, Yoshihiro Miyata, Morihito Okada and Satoshi Tashiro

    Version of Record online : 16 MAR 2016, DOI: 10.1111/cas.12899

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    Glucose metabolism-targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor-induced drug-tolerant persisters

    Cancer Science

    Volume 108, Issue 7, July 2017, Pages: 1368–1377, Kei Kunimasa, Tatsuya Nagano, Yohei Shimono, Ryota Dokuni, Tatsunori Kiriu, Shuntaro Tokunaga, Daisuke Tamura, Masatsugu Yamamoto, Motoko Tachihara, Kazuyuki Kobayashi, Miyako Satouchi and Yoshihiro Nishimura

    Version of Record online : 19 JUN 2017, DOI: 10.1111/cas.13266

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    Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification

    Cancer Science

    Volume 105, Issue 10, October 2014, Pages: 1245–1253, Won-Jun Jang, Sung-Keun Jung, Jong-Soon Kang, Joo-Won Jeong, Moon-Kyoung Bae, Sang Hoon Joo, Gyu Hwan Park, Joydeb K. Kundu, Young-Soo Hong and Chul-Ho Jeong

    Version of Record online : 25 SEP 2014, DOI: 10.1111/cas.12497

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    Effects of Src inhibitors on cell growth and epidermal growth factor receptor and MET signaling in gefitinib-resistant non-small cell lung cancer cells with acquired MET amplification

    Cancer Science

    Volume 101, Issue 1, January 2010, Pages: 167–172, Takeshi Yoshida, Isamu Okamoto, Wataru Okamoto, Erina Hatashita, Yuki Yamada, Kiyoko Kuwata, Kazuto Nishio, Masahiro Fukuoka, Pasi A. Jänne and Kazuhiko Nakagawa

    Version of Record online : 14 SEP 2009, DOI: 10.1111/j.1349-7006.2009.01368.x

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    Clinical outcomes in non-small-cell lung cancer patients with EGFR mutations: pooled analysis

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 1-2, January-February 2010, Pages: 51–69, Luis Paz-Ares, Denis Soulières, Ivan Melezínek, Joachim Moecks, Lorenz Keil, Tony Mok, Rafael Rosell and Barbara Klughammer

    Version of Record online : 8 DEC 2009, DOI: 10.1111/j.1582-4934.2009.00991.x

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    Salvage treatment with erlotinib after gefitinib failure in advanced non-small-cell lung cancer patients with poor performance status: A matched-pair case–control study

    Thoracic Cancer

    Volume 3, Issue 1, February 2012, Pages: 27–33, Daxian Luo, Meijuan Huang, Xinxing Zhang, Min Yu, Bingwen Zou, Yanying Li, Jianlin Long, Jin Wang, Feng Peng, Yong Xu, Lu Li, Li Ren, Mei Hou and You Lu

    Version of Record online : 5 FEB 2012, DOI: 10.1111/j.1759-7714.2011.00087.x

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    Epidermal growth factor receptor mutation-guided treatment for lung cancers: Where are we now?

    Thoracic Cancer

    Volume 2, Issue 1, February 2011, Pages: 1–6, Zengliu Su

    Version of Record online : 1 FEB 2011, DOI: 10.1111/j.1759-7714.2010.00035.x

  15. Butein, a novel dual inhibitor of MET and EGFR, overcomes gefitinib-resistant lung cancer growth

    Molecular Carcinogenesis

    Volume 54, Issue 4, April 2015, Pages: 322–331, Sung Keun Jung, Mee-Hyun Lee, Do Young Lim, Sung Young Lee, Chul-Ho Jeong, Jong Eun Kim, Tae Gyu Lim, Hanyong Chen, Ann M. Bode, Hyong Joo Lee, Ki Won Lee and Zigang Dong

    Version of Record online : 29 JUN 2014, DOI: 10.1002/mc.22191

  16. Integrin beta1 over-expression associates with resistance to tyrosine kinase inhibitor gefitinib in non-small cell lung cancer

    Journal of Cellular Biochemistry

    Volume 111, Issue 6, 15 December 2010, Pages: 1565–1574, Lixia Ju, Caicun Zhou, Wei Li and Linghua Yan

    Version of Record online : 29 NOV 2010, DOI: 10.1002/jcb.22888

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    JAK2-related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor-activating mutation

    Cancer Science

    Volume 103, Issue 10, October 2012, Pages: 1795–1802, Daijiro Harada, Nagio Takigawa, Nobuaki Ochi, Takashi Ninomiya, Masayuki Yasugi, Toshio Kubo, Hiromasa Takeda, Eiki Ichihara, Kadoaki Ohashi, Saburo Takata, Mitsune Tanimoto and Katsuyuki Kiura

    Version of Record online : 23 JUL 2012, DOI: 10.1111/j.1349-7006.2012.02363.x

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    Targeted Inhibition of Kinases in Cancer Therapy

    Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine

    Volume 77, Issue 6, November/December 2010, Pages: 573–586, Stacey J. Baker and E. Premkumar Reddy

    Version of Record online : 23 NOV 2010, DOI: 10.1002/msj.20220

  19. γ Secretase Inhibitor BMS-708163 Reverses Resistance to EGFR Inhibitor via the PI3K/Akt Pathway in Lung Cancer

    Journal of Cellular Biochemistry

    Volume 116, Issue 6, June 2015, Pages: 1019–1027, Mian Xie, Jianxing He, Chaosheng He and Shenhai Wei

    Version of Record online : 10 APR 2015, DOI: 10.1002/jcb.25056

  20. You have full text access to this OnlineOpen article
    RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer

    Cancer Science

    Volume 105, Issue 7, July 2014, Pages: 788–794, Naoki Kaneto, Satoru Yokoyama, Yoshihiro Hayakawa, Shinichiro Kato, Hiroaki Sakurai and Ikuo Saiki

    Version of Record online : 15 MAY 2014, DOI: 10.1111/cas.12425