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There are 10792 results for: content related to: Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery

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    Unraveling the Energetics and Mode of the Recognition of Antibiotics Tetracycline and Rolitetracycline by Bovine Serum Albumin

    Chemical Biology & Drug Design

    Volume 80, Issue 5, November 2012, Pages: 693–705, Sinjan Choudhary and Nand Kishore

    Article first published online : 31 AUG 2012, DOI: 10.1111/cbdd.12009

  2. Advances in the Prediction of Protein–Peptide Binding Affinities: Implications for Peptide-Based Drug Discovery

    Chemical Biology & Drug Design

    Volume 81, Issue 1, January 2013, Pages: 50–60, Joseph Audie and Jon Swanson

    Article first published online : 17 DEC 2012, DOI: 10.1111/cbdd.12076

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    Computational Studies of Novel Chymase Inhibitors Against Cardiovascular and Allergic Diseases: Mechanism and Inhibition

    Chemical Biology & Drug Design

    Volume 80, Issue 6, December 2012, Pages: 862–875, Mahreen Arooj, Sundarapandian Thangapandian, Shalini John, Swan Hwang, Jong K. Park and Keun W. Lee

    Article first published online : 25 OCT 2012, DOI: 10.1111/cbdd.12006

  4. Structure-Based Design and Synthesis of Benzothiazole Phosphonate Analogues with Inhibitors of Human ABAD-Aβ for Treatment of Alzheimer’s Disease

    Chemical Biology & Drug Design

    Volume 81, Issue 2, February 2013, Pages: 238–249, Koteswara R. Valasani, Gang Hu, Michael O. Chaney and Shirley S. Yan

    Article first published online : 14 NOV 2012, DOI: 10.1111/cbdd.12068

  5. Investigation into Potent Inflammation Inhibitors from Traditional Chinese Medicine

    Chemical Biology & Drug Design

    Volume 78, Issue 4, October 2011, Pages: 679–688, Kuan-Chung Chen, Mao-Feng Sun, Shun-Chieh Yang, Su-Sen Chang, Hsin-Yi Chen, Fuu-Jen Tsai and Calvin Yu-Chian Chen

    Article first published online : 6 SEP 2011, DOI: 10.1111/j.1747-0285.2011.01202.x

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    Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors

    Chemical Biology & Drug Design

    Volume 80, Issue 6, December 2012, Pages: 876–886, Valeria Sorrenti, Salvatore Guccione, Claudia Di Giacomo, Maria N. Modica, Valeria Pittalà, Rosaria Acquaviva, Livia Basile, Morena Pappalardo and Loredana Salerno

    Article first published online : 9 OCT 2012, DOI: 10.1111/cbdd.12015

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    CASE Plots for the Chemotype-Based Activity and Selectivity Analysis: A CASE Study of Cyclooxygenase Inhibitors

    Chemical Biology & Drug Design

    Volume 80, Issue 5, November 2012, Pages: 752–762, Jaime Pérez-Villanueva, José L. Medina-Franco, Oscar Méndez-Lucio, Jakyung Yoo, Olivia Soria-Arteche, Teresa Izquierdo, M. Concepción Lozada and Rafael Castillo

    Article first published online : 10 SEP 2012, DOI: 10.1111/cbdd.12019

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    Vicinal Diamino Functionalities as Privileged Structural Elements in Biologically Active Compounds and Exploitation of their Synthetic Chemistry

    Chemical Biology & Drug Design

    Volume 67, Issue 2, February 2006, Pages: 101–114, S. R. S. Saibabu Kotti, Cody Timmons and Guigen Li

    Article first published online : 14 FEB 2006, DOI: 10.1111/j.1747-0285.2006.00347.x

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    3D-QSAR Studies of JNK1 Inhibitors Utilizing Various Alignment Methods

    Chemical Biology & Drug Design

    Volume 79, Issue 1, January 2012, Pages: 53–67, Thirumurthy Madhavan, Jae Yoon Chung, Gugan Kothandan, Changdev G. Gadhe and Seung Joo Cho

    Article first published online : 4 NOV 2011, DOI: 10.1111/j.1747-0285.2011.01168.x

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    Tumor Necrosis Factor Alpha Converting Enzyme: An Encouraging Target for Various Inflammatory Disorders

    Chemical Biology & Drug Design

    Volume 75, Issue 5, May 2010, Pages: 415–443, Malkeet S. Bahia and Om Silakari

    Article first published online : 12 MAR 2010, DOI: 10.1111/j.1747-0285.2010.00950.x

  11. Activity Prediction of Some Nontested Anticancer Compounds Using GA-Based PLS Regression Models

    Chemical Biology & Drug Design

    Volume 78, Issue 4, October 2011, Pages: 587–595, Sisir Nandi and Manish C. Bagchi

    Article first published online : 25 AUG 2011, DOI: 10.1111/j.1747-0285.2011.01177.x

  12. Mechanistic-Based Descriptors for QSAR Study of Psychotropic Drug Toxicity

    Chemical Biology & Drug Design

    Volume 72, Issue 5, November 2008, Pages: 409–435, Mahnaz Esteki and Taghi Khayamian

    Article first published online : 16 OCT 2008, DOI: 10.1111/j.1747-0285.2008.00718.x

  13. Medicine pipeline: Structure-Based Drug Design and the Discovery of Aliskiren (Tekturna®): Perseverance and Creativity to Overcome a R&D Pipeline Challenge

    Chemical Biology & Drug Design

    Volume 70, Issue 6, December 2007, Pages: 557–565, Nissim Claude Cohen

    Article first published online : 12 NOV 2007, DOI: 10.1111/j.1747-0285.2007.00599.x

  14. Computational Study of the Binding Mode of Epidermal Growth Factor Receptor Kinase Inhibitors

    Chemical Biology & Drug Design

    Volume 71, Issue 5, May 2008, Pages: 434–446, Hai-Feng Chen

    Article first published online : 25 MAR 2008, DOI: 10.1111/j.1747-0285.2008.00656.x

  15. Discovery of New Antifungal Leads via Pharmacophore Modeling and QSAR Analysis of Fungal N-Myristoyl Transferase Inhibitors Followed by In Silico Screening

    Chemical Biology & Drug Design

    Volume 78, Issue 3, September 2011, Pages: 391–407, Mutasem O. Taha, Amjad M. Qandil, Tariq Al-Haraznah, Reema Abu Khalaf, Hiba Zalloum and Amal G. Al-Bakri

    Article first published online : 13 JUL 2011, DOI: 10.1111/j.1747-0285.2011.01160.x

  16. QSAR Analysis for Some Diaryl-substituted Pyrazoles as CCR2 Inhibitors by GA-Stepwise MLR

    Chemical Biology & Drug Design

    Volume 77, Issue 1, January 2011, Pages: 75–85, Lotfollah Saghaie, Mohsen Shahlaei, Afshin Fassihi, Armin Madadkar-Sobhani, Mohammad B. Gholivand and Alireza Pourhossein

    Article first published online : 30 NOV 2010, DOI: 10.1111/j.1747-0285.2010.01053.x

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    Synthesis and Kinetic Testing of Tetrahydropyrimidine-2-thione and Pyrrole Derivatives as Inhibitors of the Metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa

    Chemical Biology & Drug Design

    Volume 80, Issue 4, October 2012, Pages: 500–515, Waleed M. Hussein, Samar S. Fatahala, Zainab M. Mohamed, Ross P. McGeary, Gerhard Schenk, David L. Ollis and Mosaad S. Mohamed

    Article first published online : 23 JUL 2012, DOI: 10.1111/j.1747-0285.2012.01440.x

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    Pharmacophore and QSAR Studies to Design Novel Histone Deacetylase 2 Inhibitors

    Chemical Biology & Drug Design

    Volume 79, Issue 5, May 2012, Pages: 760–770, Yuhong Xiang, Zhaoyan Hou and Zhuoyong Zhang

    Article first published online : 15 FEB 2012, DOI: 10.1111/j.1747-0285.2012.01341.x

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    Prodrugs of Acyclovir – A Computational Approach

    Chemical Biology & Drug Design

    Volume 79, Issue 5, May 2012, Pages: 819–834, Rafik Karaman, Khuloud K. Dajani, Alaa Qtait and Mustafa Khamis

    Article first published online : 15 FEB 2012, DOI: 10.1111/j.1747-0285.2012.01335.x

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    Synthesis, Biological Evaluation, Mechanism of Action and Quantitative Structure–Activity Relationship Studies of Chalcones as Antibacterial Agents

    Chemical Biology & Drug Design

    Volume 73, Issue 4, April 2009, Pages: 403–415, Ponnurengam Malliappan Sivakumar, Sobana Priya and Mukesh Doble

    Article first published online : 6 MAR 2009, DOI: 10.1111/j.1747-0285.2009.00793.x