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There are 12769 results for: content related to: Conformational Adaptation Drives Potent, Selective and Durable Inhibition of the Human Protein Methyltransferase DOT1L

  1. MLL Leukemia and Future Treatment Strategies

    Archiv der Pharmazie

    Volume 348, Issue 4, April 2015, Pages: 221–228, Rolf Marschalek

    Version of Record online : 4 MAR 2015, DOI: 10.1002/ardp.201400449

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    Targeting the histone orthography of cancer: drugs for writers, erasers and readers

    British Journal of Pharmacology

    Volume 172, Issue 11, June 2015, Pages: 2716–2732, Laia Simó-Riudalbas and Manel Esteller

    Version of Record online : 5 SEP 2014, DOI: 10.1111/bph.12844

  3. Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor

    Biopharmaceutics & Drug Disposition

    Volume 35, Issue 4, May 2014, Pages: 237–252, Aravind Basavapathruni, Edward J. Olhava, Scott R. Daigle, Carly A. Therkelsen, Lei Jin, P. Ann Boriack-Sjodin, Christina J. Allain, Christine R. Klaus, Alejandra Raimondi, Margaret Porter Scott, Angelos Dovletoglou, Victoria M. Richon, Roy M. Pollock, Robert A. Copeland, Mikel P. Moyer, Richard Chesworth, Paul G. Pearson and Nigel J. Waters

    Version of Record online : 14 FEB 2014, DOI: 10.1002/bdd.1889

  4. Selective inhibition of preribosomal RNA synthesis by puromycin aminonucleoside in transformed human fibroblasts: Studies of the nature of the inhibition in isolated nuclei and nucleoli

    Journal of Cellular Physiology

    Volume 99, Issue 1, April 1979, Pages: 55–66, Ernest A. Albanese and George P. Studzinski

    Version of Record online : 4 FEB 2005, DOI: 10.1002/jcp.1040990108

  5. Menin as a hub controlling mixed lineage leukemia

    BioEssays

    Volume 34, Issue 9, September 2012, Pages: 771–780, Austin T. Thiel, Jing Huang, Ming Lei and Xianxin Hua

    Version of Record online : 24 JUL 2012, DOI: 10.1002/bies.201200007

  6. Anionic site and immunogold quantitation of heparan sulfate proteoglycans in glomerular basement membranes of puromycin aminonucleoside nephrotic rats

    The Anatomical Record

    Volume 231, Issue 1, September 1991, Pages: 35–47, Jody A. Rada and Dr. Edward C. Carlson

    Version of Record online : 26 JAN 2005, DOI: 10.1002/ar.1092310106

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    ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors

    International Journal of Cancer

    Volume 137, Issue 8, 15 October 2015, Pages: 2007–2018, Ping Zhang, Mark C. de Gooijer, Levi C.M. Buil, Jos H. Beijnen, Gang Li and Olaf van Tellingen

    Version of Record online : 24 APR 2015, DOI: 10.1002/ijc.29566

  8. A morphometric, biochemical and histochemical comparison of puromycin aminonucleoside and hyperalbuminaemic induced proteinurias in the female Wistar rat

    The Journal of Pathology

    Volume 139, Issue 2, February 1983, Pages: 115–140, Gillian M. Lawrence and D. B. Brewer

    Version of Record online : 16 JUN 2005, DOI: 10.1002/path.1711390204

  9. Selective inhibition of the cell cycle of cultured human diploid fibroblasts by aminonucleoside of puromycin

    Journal of Cellular Physiology

    Volume 81, Issue 1, February 1973, Pages: 71–83, George P. Studzinski and John F. Gierthy

    Version of Record online : 4 FEB 2005, DOI: 10.1002/jcp.1040810109

  10. Epigenetics in T-cell acute lymphoblastic leukemia

    Immunological Reviews

    Volume 263, Issue 1, January 2015, Pages: 50–67, Sofie Peirs, Joni Van der Meulen, Inge Van de Walle, Tom Taghon, Frank Speleman, Bruce Poppe and Pieter Van Vlierberghe

    Version of Record online : 15 DEC 2014, DOI: 10.1111/imr.12237

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    Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases

    The EMBO Journal

    Volume 31, Issue 9, May 2, 2012, Pages: 2169–2181, Timothy P Wakeman, Qinhong Wang, Junjie Feng and Xiao-Fan Wang

    Version of Record online : 28 FEB 2012, DOI: 10.1038/emboj.2012.50

  12. Key molecular events in puromycin aminonucleoside nephrosis rats

    Pathology International

    Volume 54, Issue 9, September 2004, Pages: 703–711, Na Guan, Jie Ding, Jianghong Deng, Jingjing Zhang and Jiyun Yang

    Version of Record online : 3 SEP 2004, DOI: 10.1111/j.1440-1827.2004.01683.x

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    DOT1L Activity Promotes Proliferation and Protects Cortical Neural Stem Cells from Activation of ATF4-DDIT3-Mediated ER Stress In Vitro

    STEM CELLS

    Volume 34, Issue 1, January 2016, Pages: 233–245, Deborah Roidl, Nicole Hellbach, Patrick P. Bovio, Alejandro Villarreal, Stefanie Heidrich, Sigrun Nestel, Björn A. Grüning, Ulrike Boenisch and Tanja Vogel

    Version of Record online : 29 SEP 2015, DOI: 10.1002/stem.2187

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    CXCL10 induces the recruitment of monocyte-derived macrophages into kidney, which aggravate puromycin aminonucleoside nephrosis

    Clinical & Experimental Immunology

    Volume 180, Issue 2, May 2015, Pages: 305–315, D. Petrovic-Djergovic, M. Popovic, S. Chittiprol, H. Cortado, R. F. Ransom and S. Partida-Sánchez

    Version of Record online : 14 APR 2015, DOI: 10.1111/cei.12579

  15. ASCITES FLUID OF NEPHROTIC RATS: SODIUM DODECYL SULPHATE-POLYACRYLAMIDE GEL ELECTROPHORESIS PROTEIN PATTERN AND THE RENIN-ANGIOTENSIN SYSTEM

    Clinical and Experimental Pharmacology and Physiology

    Volume 25, Issue 7-8, August 1998, Pages: 568–571, C. Cruz, R. Correa-Rotter, C. Mézquita, ON Medina-Campos and J. Pedraza-Chaverri

    Version of Record online : 28 JUN 2007, DOI: 10.1111/j.1440-1681.1998.tb02253.x

  16. Morphometric Changes in Glomerular Anionic Sites during Aminonucleoside Nephrosis

    Pathology International

    Volume 39, Issue 9, September 1989, Pages: 558–565, Kazuhiko Washizawa, Keiko Ishii, Nobuo Itoh, Tetsuo Mori, Taro Akabane and Hidekazu Shigematsu

    Version of Record online : 11 DEC 2008, DOI: 10.1111/j.1440-1827.1989.tb02484.x

  17. Ferritin deposition in the glomerular deposits of focal glomerular sclerosis in the rat

    The Journal of Pathology

    Volume 144, Issue 1, September 1984, Pages: 45–55, Celine Melcion, Jennifer Smith and Victoria Cattell

    Version of Record online : 15 JUN 2005, DOI: 10.1002/path.1711440106

  18. Increased oxidative stress and apoptosis in acute puromycin aminonucleoside nephrosis

    International Journal of Experimental Pathology

    Volume 85, Issue 1, February 2004, Pages: 25–33, Jaimar Rincon, Maritza Romero, Ninoska Viera, Adriana Pedrean˜ez and Jesus Mosquera

    Version of Record online : 26 APR 2004, DOI: 10.1111/j.0959-9673.2004.0368.x

  19. Small-Molecule Modulators for Epigenetics Targets

    ChemMedChem

    Volume 8, Issue 11, November 2013, Pages: 1885–1891, Prof. Dr. Stefan Knapp and Prof. Dr. Hilmar Weinmann

    Version of Record online : 14 OCT 2013, DOI: 10.1002/cmdc.201300344

    Corrected by:

    Corrigendum: Corrigendum: Small-Molecule Modulators for Epigenetics Targets

    Vol. 8, Issue 12, 1904, Version of Record online: 29 NOV 2013

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    Concise Review: Leukemia Stem Cells in Personalized Medicine

    STEM CELLS

    Volume 32, Issue 4, April 2014, Pages: 844–851, Monica L. Guzman and John N. Allan

    Version of Record online : 17 MAR 2014, DOI: 10.1002/stem.1597