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There are 163075 results for: content related to: Optimization of CD4/gp120 Inhibitors by Thermodynamic-Guided Alanine-Scanning Mutagenesis

  1. Mechanistic-Based Descriptors for QSAR Study of Psychotropic Drug Toxicity

    Chemical Biology & Drug Design

    Volume 72, Issue 5, November 2008, Pages: 409–435, Mahnaz Esteki and Taghi Khayamian

    Article first published online : 16 OCT 2008, DOI: 10.1111/j.1747-0285.2008.00718.x

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    Vicinal Diamino Functionalities as Privileged Structural Elements in Biologically Active Compounds and Exploitation of their Synthetic Chemistry

    Chemical Biology & Drug Design

    Volume 67, Issue 2, February 2006, Pages: 101–114, S. R. S. Saibabu Kotti, Cody Timmons and Guigen Li

    Article first published online : 14 FEB 2006, DOI: 10.1111/j.1747-0285.2006.00347.x

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    Synthesis, Biological Evaluation, Mechanism of Action and Quantitative Structure–Activity Relationship Studies of Chalcones as Antibacterial Agents

    Chemical Biology & Drug Design

    Volume 73, Issue 4, April 2009, Pages: 403–415, Ponnurengam Malliappan Sivakumar, Sobana Priya and Mukesh Doble

    Article first published online : 6 MAR 2009, DOI: 10.1111/j.1747-0285.2009.00793.x

  4. Comparative QSAR Study on Para-substituted Aromatic Sulphonamides as CAII Inhibitors: Information versus Topological (Distance-Based and Connectivity) Indices

    Chemical Biology & Drug Design

    Volume 71, Issue 3, March 2008, Pages: 244–259, Jyoti Singh, Basheerulla Shaik, Shalini Singh, Vijay K. Agrawal, Padmakar V. Khadikar, Omar Deeb and Claudiu T. Supuran

    Article first published online : 21 JAN 2008, DOI: 10.1111/j.1747-0285.2007.00625.x

  5. DFT-based de novo QSAR of Phenoloxidase Inhibitors

    Chemical Biology & Drug Design

    Volume 71, Issue 5, May 2008, Pages: 483–493, Farhan Ahmad Pasha, Muhhammad Muddassar, Yakub Beg and Seung Joo Cho

    Article first published online : 8 APR 2008, DOI: 10.1111/j.1747-0285.2008.00651.x

  6. Quantitative Structure–Activity Relationship and Classification Analysis of Diaryl Ureas Against Vascular Endothelial Growth Factor Receptor-2 Kinase Using Linear and Non-Linear Models

    Chemical Biology & Drug Design

    Volume 73, Issue 6, June 2009, Pages: 644–654, Min Sun, Junqing Chen, Hongtao Wei, Shuangqing Yin, Yan Yang and Min Ji

    Article first published online : 17 APR 2009, DOI: 10.1111/j.1747-0285.2009.00814.x

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    Tumor Necrosis Factor Alpha Converting Enzyme: An Encouraging Target for Various Inflammatory Disorders

    Chemical Biology & Drug Design

    Volume 75, Issue 5, May 2010, Pages: 415–443, Malkeet S. Bahia and Om Silakari

    Article first published online : 12 MAR 2010, DOI: 10.1111/j.1747-0285.2010.00950.x

  8. Medicine pipeline: Structure-Based Drug Design and the Discovery of Aliskiren (Tekturna®): Perseverance and Creativity to Overcome a R&D Pipeline Challenge

    Chemical Biology & Drug Design

    Volume 70, Issue 6, December 2007, Pages: 557–565, Nissim Claude Cohen

    Article first published online : 12 NOV 2007, DOI: 10.1111/j.1747-0285.2007.00599.x

  9. Computational Study of the Binding Mode of Epidermal Growth Factor Receptor Kinase Inhibitors

    Chemical Biology & Drug Design

    Volume 71, Issue 5, May 2008, Pages: 434–446, Hai-Feng Chen

    Article first published online : 25 MAR 2008, DOI: 10.1111/j.1747-0285.2008.00656.x

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    Fluorescent Indolylboronic Acids that are Useful Reporters for the Synthesis of Boronolectins

    Chemical Biology & Drug Design

    Volume 67, Issue 2, February 2006, Pages: 137–144, Junfeng Wang, Shan Jin, Na Lin and Binghe Wang

    Article first published online : 31 JAN 2006, DOI: 10.1111/j.1747-0285.2005.00338.x

  11. QSTR with Extended Topochemical Atom Indices. 10. Modeling of Toxicity of Organic Chemicals to Humans Using Different Chemometric Tools

    Chemical Biology & Drug Design

    Volume 72, Issue 5, November 2008, Pages: 383–394, Kunal Roy and Gopinath Ghosh

    Article first published online : 16 OCT 2008, DOI: 10.1111/j.1747-0285.2008.00712.x

  12. QSAR Studies of CYP2D6 Inhibitor Aryloxypropanolamines Using 2D and 3D Descriptors

    Chemical Biology & Drug Design

    Volume 73, Issue 4, April 2009, Pages: 442–455, Partha Pratim Roy and Kunal Roy

    Article first published online : 6 MAR 2009, DOI: 10.1111/j.1747-0285.2009.00791.x

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    Simultaneously Optimized Support Vector Regression Combined With Genetic Algorithm for QSAR Analysis of KDR/VEGFR-2 Inhibitors

    Chemical Biology & Drug Design

    Volume 75, Issue 5, May 2010, Pages: 494–505, Min Sun, Junqing Chen, Jin Cai, Meng Cao, Shuangqing Yin and Min Ji

    Article first published online : 12 MAR 2010, DOI: 10.1111/j.1747-0285.2010.00958.x

  14. A Molecular Basis for Agonist and Antagonist Actions at GABAC Receptors

    Chemical Biology & Drug Design

    Volume 71, Issue 4, April 2008, Pages: 306–327, Heba Abdel-Halim, Jane R. Hanrahan, David E. Hibbs, Graham A. R. Johnston and Mary Chebib

    Article first published online : 28 FEB 2008, DOI: 10.1111/j.1747-0285.2008.00642.x

  15. Natural Compounds: Leads or Ideas? Bioinspired Molecules for Drug Discovery

    Chemical Biology & Drug Design

    Volume 72, Issue 1, July 2008, Pages: 3–15, Terence Beghyn, Rebecca Deprez-Poulain, Nicolas Willand, Benoit Folleas and Benoit Deprez

    Article first published online : 28 JUN 2008, DOI: 10.1111/j.1747-0285.2008.00673.x

  16. Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery

    Chemical Biology & Drug Design

    Volume 81, Issue 1, January 2013, Pages: 148–165, Andrew G. Jamieson, Nicolas Boutard, David Sabatino and William D. Lubell

    Article first published online : 17 DEC 2012, DOI: 10.1111/cbdd.12042

  17. A Similarity-based Data-fusion Approach to the Visual Characterization and Comparison of Compound Databases

    Chemical Biology & Drug Design

    Volume 70, Issue 5, November 2007, Pages: 393–412, José L. Medina-Franco, Gerald M. Maggiora, Marc A. Giulianotti, Clemencia Pinilla and Richard A. Houghten

    Article first published online : 10 OCT 2007, DOI: 10.1111/j.1747-0285.2007.00579.x

  18. Mutagenicity of Nitrated Polycyclic Aromatic Hydrocarbons: A QSAR Investigation

    Chemical Biology & Drug Design

    Volume 71, Issue 3, March 2008, Pages: 230–243, Jyoti Singh, Shalini Singh, Basheerulla Shaik, Omar Deeb, Neena Sohani, Vijay K. Agrawal and Padmakar V. Khadikar

    Article first published online : 30 JAN 2008, DOI: 10.1111/j.1747-0285.2008.00629.x

  19. In Silico Quantitative Structure–Toxicity Relationship Study of Aromatic Nitro Compounds

    Chemical Biology & Drug Design

    Volume 73, Issue 5, May 2009, Pages: 537–544, Farhan Ahmad Pasha, Mohammad Morshed Neaz, Seung Joo Cho, Mohiuddin Ansari, Sunil Kumar Mishra and Sharvan Tiwari

    Article first published online : 23 MAR 2009, DOI: 10.1111/j.1747-0285.2009.00799.x

  20. Analysis of Crystal Structures of LXRβ in Relation to Plasticity of the Ligand-Binding Domain upon Ligand Binding

    Chemical Biology & Drug Design

    Volume 71, Issue 2, February 2008, Pages: 140–154, Nagulapalli Malini, Hariharan Rajesh, Pooja Berwal, Samiron Phukan and Vittukudi Narayanaiyengar Balaji

    Article first published online : 22 JAN 2008, DOI: 10.1111/j.1747-0285.2007.00620.x