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There are 13732 results for: content related to: Investigating Mammalian Tyrosine Phosphatase Inhibitors as Potential ‘Piggyback’ Leads to Target Trypanosoma brucei Transmission

  1. The Discovery of a Novel and Selective Inhibitor of PTP1B Over TCPTP: 3D QSAR Pharmacophore Modeling, Virtual Screening, Synthesis, and Biological Evaluation

    Chemical Biology & Drug Design

    Volume 83, Issue 6, June 2014, Pages: 697–709, Ying Ma, Yuan-Yuan Jin, Ye-Liu Wang, Run-Ling Wang, Xin-Hua Lu, De-Xin Kong and Wei-Ren Xu

    Article first published online : 15 MAY 2014, DOI: 10.1111/cbdd.12283

  2. Design and Synthesis of Imidazolidine-2,4-Dione Derivatives as Selective Inhibitors by Targeting Protein Tyrosine Phosphatase-1B Over T-Cell Protein Tyrosine Phosphatase

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 595–602, Ying Ma, Su-Xia Sun, Xian-Chao Cheng, Shu-Qing Wang, Wei-Li Dong, Run-Ling Wang and Wei-Ren Xu

    Article first published online : 21 AUG 2013, DOI: 10.1111/cbdd.12189

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    Synthesis and Biological Evaluation of 2,4,6-Trihydroxychalcone Derivatives as Novel Protein Tyrosine Phosphatase 1B Inhibitors

    Chemical Biology & Drug Design

    Volume 80, Issue 4, October 2012, Pages: 584–590, Liang-Peng Sun, Li-Xin Gao, Wei-Ping Ma, Fa-Jun Nan, Jia Li and Hu-Ri Piao

    Article first published online : 13 JUL 2012, DOI: 10.1111/j.1747-0285.2012.01431.x

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    Classification of Binding Site Conformations of Protein Tyrosine Phosphatase 1B

    Chemical Biology & Drug Design

    Volume 80, Issue 1, July 2012, Pages: 121–128, Vsevolod Yu. Tanchuk, Volodymyr O. Tanin and Andriy I. Vovk

    Article first published online : 27 APR 2012, DOI: 10.1111/j.1747-0285.2012.01370.x

  5. TS-Chemscore, a Target-Specific Scoring Function, Significantly Improves the Performance of Scoring in Virtual Screening

    Chemical Biology & Drug Design

    Wen-Jing Wang, Qi Huang, Jun Zou, Lin-Li Li and Sheng-Yong Yang

    Article first published online : 8 DEC 2014, DOI: 10.1111/cbdd.12470

  6. Rationalizing Protein–Ligand Interactions for PTP1B Inhibitors Using Computational Methods

    Chemical Biology & Drug Design

    Volume 74, Issue 6, December 2009, Pages: 582–595, Subhash Ajmani, Sudheer Karanam and Sudhir A. Kulkarni

    Article first published online : 12 OCT 2009, DOI: 10.1111/j.1747-0285.2009.00894.x

  7. In silico Target Fishing for the Potential Targets and Molecular Mechanisms of Baicalein as an Antiparkinsonian Agent: Discovery of the Protective Effects on NMDA Receptor-Mediated Neurotoxicity

    Chemical Biology & Drug Design

    Volume 81, Issue 6, June 2013, Pages: 675–687, Li Gao, Jian-Song Fang, Xiao-Yu Bai, Dan Zhou, Yi-Tao Wang, Ai-Lin Liu and Guan-Hua Du

    Article first published online : 25 MAY 2013, DOI: 10.1111/cbdd.12127

  8. Triazole: A Promising Antitubercular Agent

    Chemical Biology & Drug Design

    Rangappa S. Keri, Siddappa A. Patil, Srinivasa Budagumpi and Bhari Mallanna Nagaraja

    Article first published online : 19 FEB 2015, DOI: 10.1111/cbdd.12527

  9. Potassium Channels: Structures, Diseases, and Modulators

    Chemical Biology & Drug Design

    Volume 83, Issue 1, January 2014, Pages: 1–26, Chuan Tian, Ruixin Zhu, Lixin Zhu, Tianyi Qiu, Zhiwei Cao and Tingguo Kang

    Article first published online : 23 DEC 2013, DOI: 10.1111/cbdd.12237

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    Cantharidin-Based Small Molecules as Potential Therapeutic Agents

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 477–499, Carlos E. Puerto Galvis, Leonor Y. Vargas Méndez and Vladimir V. Kouznetsov

    Article first published online : 8 AUG 2013, DOI: 10.1111/cbdd.12180

  11. Comprehensive Review in Current Developments of Benzimidazole-Based Medicinal Chemistry

    Chemical Biology & Drug Design

    Rangappa S. Keri, Asha Hiremathad, Srinivasa Budagumpi and Bhari Mallanna Nagaraja

    Article first published online : 28 NOV 2014, DOI: 10.1111/cbdd.12462

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    1,3,4-Thiadiazole and its Derivatives: A Review on Recent Progress in Biological Activities

    Chemical Biology & Drug Design

    Volume 81, Issue 5, May 2013, Pages: 557–576, Abhishek Kumar Jain, Simant Sharma, Ankur Vaidya, Veerasamy Ravichandran and Ram Kishore Agrawal

    Article first published online : 24 APR 2013, DOI: 10.1111/cbdd.12125

  13. Differential Modulation in Binding of Ketoprofen to Bovine Serum Albumin in the Presence and Absence of Surfactants: Spectroscopic and Calorimetric Insights

    Chemical Biology & Drug Design

    Volume 82, Issue 1, July 2013, Pages: 81–98, Pinaki P. Misra and Nand Kishore

    Article first published online : 21 JUN 2013, DOI: 10.1111/cbdd.12136

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    Lead Optimization on Conventional Non-Steroidal Anti-Inflammatory Drugs: An Approach to Reduce Gastrointestinal Toxicity

    Chemical Biology & Drug Design

    Volume 84, Issue 1, July 2014, Pages: 1–23, Tamanna Narsinghani and Rajesh Sharma

    Article first published online : 13 MAR 2014, DOI: 10.1111/cbdd.12292

  15. Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein–Protein Interaction by a Scaffold-Hopping Approach

    Chemical Biology & Drug Design

    Andrey Zaytsev, Barry Dodd, Matteo Magnani, Chiara Ghiron, Bernard T. Golding, Roger J. Griffin, Junfeng Liu, Xiaohong Lu, Iolanda Micco, David R. Newell, Alessandro Padova, Graeme Robertson, John Lunec and Ian R. Hardcastle

    Article first published online : 19 DEC 2014, DOI: 10.1111/cbdd.12474

  16. Homology Modeling, Docking Studies and Molecular Dynamic Simulations Using Graphical Processing Unit Architecture to Probe the Type-11 Phosphodiesterase Catalytic Site: A Computational Approach for the Rational Design of Selective Inhibitors

    Chemical Biology & Drug Design

    Volume 82, Issue 6, December 2013, Pages: 718–731, Elena Cichero, Pasqualina D'Ursi, Marco Moscatelli, Olga Bruno, Alessandro Orro, Chiara Rotolo, Luciano Milanesi and Paola Fossa

    Article first published online : 26 AUG 2013, DOI: 10.1111/cbdd.12193

  17. Synthesis and Cytotoxic Evaluation of Acylated Brefeldin A Derivatives as Potential Anticancer Agents

    Chemical Biology & Drug Design

    Volume 82, Issue 3, September 2013, Pages: 307–316, Bingyong He, Yajun Wang, Yuguo Zheng, Wei Chen and Qing Zhu

    Article first published online : 28 JUN 2013, DOI: 10.1111/cbdd.12154

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    Design, Synthesis, and Evaluation of 2-(arylsulfonyl)oxiranes as Cell-permeable Covalent Inhibitors of Protein Tyrosine Phosphatases

    Chemical Biology & Drug Design

    Volume 80, Issue 4, October 2012, Pages: 489–499, Dibyendu Dana, Tirtha K. Das, Ish Kumar, Anibal R. Davalos, Kevin J. Mark, Daryl Ramai, Emmanuel J. Chang, Tanaji T. Talele and Sanjai Kumar

    Article first published online : 25 JUL 2012, DOI: 10.1111/j.1747-0285.2012.01437.x

  19. Theoretical Characterization of Galanin Receptor Type 3 (Gal3) and Its Interaction with Agonist (GALANIN) and Antagonists (SNAP 37889 and SNAP 398299): An In Silico Analysis

    Chemical Biology & Drug Design

    Volume 81, Issue 6, June 2013, Pages: 757–774, Gugan Kothandan, Changdev G. Gadhe and Seung J. Cho

    Article first published online : 17 APR 2013, DOI: 10.1111/cbdd.12128

  20. Histamine H4 Receptor Ligands: Future Applications and State of Art

    Chemical Biology & Drug Design

    Michelle Fidelis Corrêa and João Paulo dos Santos Fernandes

    Article first published online : 27 OCT 2014, DOI: 10.1111/cbdd.12431