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There are 12036 results for: content related to: Investigating Mammalian Tyrosine Phosphatase Inhibitors as Potential ‘Piggyback’ Leads to Target Trypanosoma brucei Transmission

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    Synthesis and Biological Evaluation of 2,4,6-Trihydroxychalcone Derivatives as Novel Protein Tyrosine Phosphatase 1B Inhibitors

    Chemical Biology & Drug Design

    Volume 80, Issue 4, October 2012, Pages: 584–590, Liang-Peng Sun, Li-Xin Gao, Wei-Ping Ma, Fa-Jun Nan, Jia Li and Hu-Ri Piao

    Article first published online : 13 JUL 2012, DOI: 10.1111/j.1747-0285.2012.01431.x

  2. The Discovery of a Novel and Selective Inhibitor of PTP1B Over TCPTP: 3D QSAR Pharmacophore Modeling, Virtual Screening, Synthesis, and Biological Evaluation

    Chemical Biology & Drug Design

    Volume 83, Issue 6, June 2014, Pages: 697–709, Ying Ma, Yuan-Yuan Jin, Ye-Liu Wang, Run-Ling Wang, Xin-Hua Lu, De-Xin Kong and Wei-Ren Xu

    Article first published online : 15 MAY 2014, DOI: 10.1111/cbdd.12283

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    Classification of Binding Site Conformations of Protein Tyrosine Phosphatase 1B

    Chemical Biology & Drug Design

    Volume 80, Issue 1, July 2012, Pages: 121–128, Vsevolod Yu. Tanchuk, Volodymyr O. Tanin and Andriy I. Vovk

    Article first published online : 27 APR 2012, DOI: 10.1111/j.1747-0285.2012.01370.x

  4. Rationalizing Protein–Ligand Interactions for PTP1B Inhibitors Using Computational Methods

    Chemical Biology & Drug Design

    Volume 74, Issue 6, December 2009, Pages: 582–595, Subhash Ajmani, Sudheer Karanam and Sudhir A. Kulkarni

    Article first published online : 12 OCT 2009, DOI: 10.1111/j.1747-0285.2009.00894.x

  5. Design and Synthesis of Imidazolidine-2,4-Dione Derivatives as Selective Inhibitors by Targeting Protein Tyrosine Phosphatase-1B Over T-Cell Protein Tyrosine Phosphatase

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 595–602, Ying Ma, Su-Xia Sun, Xian-Chao Cheng, Shu-Qing Wang, Wei-Li Dong, Run-Ling Wang and Wei-Ren Xu

    Article first published online : 21 AUG 2013, DOI: 10.1111/cbdd.12189

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    Design, Synthesis, and Evaluation of 2-(arylsulfonyl)oxiranes as Cell-permeable Covalent Inhibitors of Protein Tyrosine Phosphatases

    Chemical Biology & Drug Design

    Volume 80, Issue 4, October 2012, Pages: 489–499, Dibyendu Dana, Tirtha K. Das, Ish Kumar, Anibal R. Davalos, Kevin J. Mark, Daryl Ramai, Emmanuel J. Chang, Tanaji T. Talele and Sanjai Kumar

    Article first published online : 25 JUL 2012, DOI: 10.1111/j.1747-0285.2012.01437.x

  7. TS-Chemscore, a Target-Specific Scoring Function, Significantly Improves the Performance of Scoring in Virtual Screening

    Chemical Biology & Drug Design

    Wen-Jing Wang, Qi Huang, Jun Zou, Lin-Li Li and Sheng-Yong Yang

    Article first published online : 8 DEC 2014, DOI: 10.1111/cbdd.12470

  8. Structure-Based Design and Synthesis of Benzothiazole Phosphonate Analogues with Inhibitors of Human ABAD-Aβ for Treatment of Alzheimer’s Disease

    Chemical Biology & Drug Design

    Volume 81, Issue 2, February 2013, Pages: 238–249, Koteswara R. Valasani, Gang Hu, Michael O. Chaney and Shirley S. Yan

    Article first published online : 14 NOV 2012, DOI: 10.1111/cbdd.12068

  9. Comprehensive Review in Current Developments of Benzimidazole-Based Medicinal Chemistry

    Chemical Biology & Drug Design

    Rangappa S. Keri, Asha Hiremathad, Srinivasa Budagumpi and Bhari Mallanna Nagaraja

    Article first published online : 28 NOV 2014, DOI: 10.1111/cbdd.12462

  10. Biomolecular Interactions of Small-molecule Inhibitors Affecting the YopH Protein Tyrosine Phosphatase

    Chemical Biology & Drug Design

    Volume 81, Issue 3, March 2013, Pages: 323–333, Megan Hogan, Medhanit Bahta, Scott Cherry, George T. Lountos, Joseph E. Tropea, Bryan M. Zhao, Terrence R. Burke Jr, David S. Waugh and Robert G. Ulrich

    Article first published online : 13 FEB 2013, DOI: 10.1111/cbdd.12097

  11. In silico Target Fishing for the Potential Targets and Molecular Mechanisms of Baicalein as an Antiparkinsonian Agent: Discovery of the Protective Effects on NMDA Receptor-Mediated Neurotoxicity

    Chemical Biology & Drug Design

    Volume 81, Issue 6, June 2013, Pages: 675–687, Li Gao, Jian-Song Fang, Xiao-Yu Bai, Dan Zhou, Yi-Tao Wang, Ai-Lin Liu and Guan-Hua Du

    Article first published online : 25 MAY 2013, DOI: 10.1111/cbdd.12127

  12. Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery

    Chemical Biology & Drug Design

    Volume 81, Issue 1, January 2013, Pages: 148–165, Andrew G. Jamieson, Nicolas Boutard, David Sabatino and William D. Lubell

    Article first published online : 17 DEC 2012, DOI: 10.1111/cbdd.12042

  13. Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein–Protein Interaction by a Scaffold-Hopping Approach

    Chemical Biology & Drug Design

    Andrey Zaytsev, Barry Dodd, Matteo Magnani, Chiara Ghiron, Bernard T. Golding, Roger J. Griffin, Junfeng Liu, Xiaohong Lu, Iolanda Micco, David R. Newell, Alessandro Padova, Graeme Robertson, John Lunec and Ian R. Hardcastle

    Article first published online : 19 DEC 2014, DOI: 10.1111/cbdd.12474

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    1,3,4-Thiadiazole and its Derivatives: A Review on Recent Progress in Biological Activities

    Chemical Biology & Drug Design

    Volume 81, Issue 5, May 2013, Pages: 557–576, Abhishek Kumar Jain, Simant Sharma, Ankur Vaidya, Veerasamy Ravichandran and Ram Kishore Agrawal

    Article first published online : 24 APR 2013, DOI: 10.1111/cbdd.12125

  15. Differential Modulation in Binding of Ketoprofen to Bovine Serum Albumin in the Presence and Absence of Surfactants: Spectroscopic and Calorimetric Insights

    Chemical Biology & Drug Design

    Volume 82, Issue 1, July 2013, Pages: 81–98, Pinaki P. Misra and Nand Kishore

    Article first published online : 21 JUN 2013, DOI: 10.1111/cbdd.12136

  16. Lead Optimization on Conventional Non-Steroidal Anti-Inflammatory Drugs: An Approach to Reduce Gastrointestinal Toxicity

    Chemical Biology & Drug Design

    Volume 84, Issue 1, July 2014, Pages: 1–23, Tamanna Narsinghani and Rajesh Sharma

    Article first published online : 13 MAR 2014, DOI: 10.1111/cbdd.12292

  17. Dynamic Change of Heme Environment in Soluble Guanylate Cyclase and Complexation of NO-Independent Drug Agents with H-NOX Domain

    Chemical Biology & Drug Design

    Volume 81, Issue 3, March 2013, Pages: 359–381, Laleh Alisaraie, Yangxin Fu and Jack A. Tuszynski

    Article first published online : 26 DEC 2012, DOI: 10.1111/cbdd.12082

  18. Advances in the Prediction of Protein–Peptide Binding Affinities: Implications for Peptide-Based Drug Discovery

    Chemical Biology & Drug Design

    Volume 81, Issue 1, January 2013, Pages: 50–60, Joseph Audie and Jon Swanson

    Article first published online : 17 DEC 2012, DOI: 10.1111/cbdd.12076

  19. Activity Prediction of Some Nontested Anticancer Compounds Using GA-Based PLS Regression Models

    Chemical Biology & Drug Design

    Volume 78, Issue 4, October 2011, Pages: 587–595, Sisir Nandi and Manish C. Bagchi

    Article first published online : 25 AUG 2011, DOI: 10.1111/j.1747-0285.2011.01177.x

  20. Discovery of New Antifungal Leads via Pharmacophore Modeling and QSAR Analysis of Fungal N-Myristoyl Transferase Inhibitors Followed by In Silico Screening

    Chemical Biology & Drug Design

    Volume 78, Issue 3, September 2011, Pages: 391–407, Mutasem O. Taha, Amjad M. Qandil, Tariq Al-Haraznah, Reema Abu Khalaf, Hiba Zalloum and Amal G. Al-Bakri

    Article first published online : 13 JUL 2011, DOI: 10.1111/j.1747-0285.2011.01160.x