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There are 28082 results for: content related to: Beyond the Hundred Dollar Genome – Drug Discovery Futures

  1. Novel Shikonin Derivatives Targeting Tubulin as Anticancer Agents

    Chemical Biology & Drug Design

    Volume 84, Issue 5, November 2014, Pages: 603–615, Jing Guo, Xiao-Feng Chen, Jing Liu, Hong-Yan Lin, Hong-Wei Han, Hong-Chang Liu, Shou-Cheng Huang, Baloch K. Shahla, Andrew Kulek, Jin-Liang Qi, Xiao-Ming Wang, Li-Jun Ling and Yong-Hua Yang

    Article first published online : 3 JUL 2014, DOI: 10.1111/cbdd.12353

  2. Drug Resistance Reversal Potential of Ursolic Acid Derivatives against Nalidixic Acid- and Multidrug-resistant Escherichia coli

    Chemical Biology & Drug Design

    Gaurav Raj Dwivedi, Anupam Maurya, Dharmendra Kumar Yadav, Feroz Khan, Mahendra P. Darokar and Santosh Kumar Srivastava

    Article first published online : 20 JAN 2015, DOI: 10.1111/cbdd.12491

  3. Comprehensive Review in Current Developments of Benzimidazole-Based Medicinal Chemistry

    Chemical Biology & Drug Design

    Volume 86, Issue 1, July 2015, Pages: 19–65, Rangappa S. Keri, Asha Hiremathad, Srinivasa Budagumpi and Bhari Mallanna Nagaraja

    Article first published online : 28 NOV 2014, DOI: 10.1111/cbdd.12462

  4. Further Insights Into the Pharmacology of the Human Trace Amine-Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach

    Chemical Biology & Drug Design

    Volume 84, Issue 6, December 2014, Pages: 712–720, Elena Cichero, Stefano Espinoza, Silvia Franchini, Sara Guariento, Livio Brasili, Raul R. Gainetdinov and Paola Fossa

    Article first published online : 29 JUN 2014, DOI: 10.1111/cbdd.12367

  5. Heat-Shock Protein 90 (Hsp90) as Anticancer Target for Drug Discovery: An Ample Computational Perspective

    Chemical Biology & Drug Design

    Hezekiel M. Kumalo, Soumendranath Bhakat and Mahmoud E. Soliman

    Article first published online : 11 JUN 2015, DOI: 10.1111/cbdd.12582

  6. Issue Information

    Chemical Biology & Drug Design

    Volume 81, Issue 3, March 2013, Pages: i–iii,

    Article first published online : 13 FEB 2013, DOI: 10.1111/cbdd.12025

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    Insight into Selectivity of Peptidomimetic Inhibitors with Modified Statine Core for Plasmepsin II of Plasmodium falciparum over Human Cathepsin D

    Chemical Biology & Drug Design

    Volume 79, Issue 4, April 2012, Pages: 411–430, Brice Dali, Melalie Keita, Eugene Megnassan, Vladimir Frecer and Stanislav Miertus

    Article first published online : 21 MAR 2012, DOI: 10.1111/j.1747-0285.2011.01276.x

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    Identifying the Molecular Mechanics and Binding Dynamics Characteristics of Potent Inhibitors to HIV-1 Protease

    Chemical Biology & Drug Design

    Volume 80, Issue 3, September 2012, Pages: 440–454, Dechang Li, Ming S. Liu, Baohua Ji, Keh-Chih Hwang and Yonggang Huang

    Article first published online : 27 JUN 2012, DOI: 10.1111/j.1747-0285.2012.01417.x

  9. Transmembrane Helix Assembly by Max–Min Ant System Algorithm

    Chemical Biology & Drug Design

    Kanon Sujaree, Sunan Kitjaruwankul, Panisak Boonamnaj, Chirayut Supunyabut and Pornthep Sompornpisut

    Article first published online : 23 JUN 2015, DOI: 10.1111/cbdd.12600

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    Tumor Necrosis Factor Alpha Converting Enzyme: An Encouraging Target for Various Inflammatory Disorders

    Chemical Biology & Drug Design

    Volume 75, Issue 5, May 2010, Pages: 415–443, Malkeet S. Bahia and Om Silakari

    Article first published online : 12 MAR 2010, DOI: 10.1111/j.1747-0285.2010.00950.x

  11. Histamine H4 Receptor Ligands: Future Applications and State of Art

    Chemical Biology & Drug Design

    Volume 85, Issue 4, April 2015, Pages: 461–480, Michelle Fidelis Corrêa and João Paulo dos Santos Fernandes

    Article first published online : 27 OCT 2014, DOI: 10.1111/cbdd.12431

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    Small Steps to New Drugs for Bugs

    Chemical Biology & Drug Design

    Volume 85, Issue 1, January 2015, Pages: 1–3, Roberta J. Melander and David L Selwood

    Article first published online : 17 DEC 2014, DOI: 10.1111/cbdd.12482

  13. Triazole: A Promising Antitubercular Agent

    Chemical Biology & Drug Design

    Rangappa S. Keri, Siddappa A. Patil, Srinivasa Budagumpi and Bhari Mallanna Nagaraja

    Article first published online : 19 FEB 2015, DOI: 10.1111/cbdd.12527

  14. Structure-based Design, Synthesis, and Biological Evaluation of Isatin Derivatives as Potential Glycosyltransferase Inhibitors

    Chemical Biology & Drug Design

    Volume 84, Issue 6, December 2014, Pages: 685–696, Yong Wang, Fung-Yi Chan, Ning Sun, Hok-Kiu Lui, Pui-Kin So, Siu-Cheong Yan, Kin-Fai Chan, Jiachi Chiou, Sheng Chen, Ruben Abagyan, Yun-Chung Leung and Kwok-Yin Wong

    Article first published online : 14 AUG 2014, DOI: 10.1111/cbdd.12361

  15. Targeting Receptor Tyrosine Kinases and Their Downstream Signaling with Cell-Penetrating Peptides in Human Pulmonary Artery Smooth Muscle and Endothelial Cells

    Chemical Biology & Drug Design

    Volume 85, Issue 5, May 2015, Pages: 586–597, Jun Yu, Chamila Rupasinghe, Jamie L. Wilson, Linda Taylor, Nader Rahimi, Dale Mierke and Peter Polgar

    Article first published online : 5 NOV 2014, DOI: 10.1111/cbdd.12446

  16. Structural Basis for Low-Affinity Binding of Non-R2 Carboxylate-Substituted Tricyclic Quinoline Analogs to CK2α: Comparative Molecular Dynamics Simulation Studies

    Chemical Biology & Drug Design

    Volume 85, Issue 2, February 2015, Pages: 189–200, Yue Zhou, Xitao Li, Na Zhang and Rugang Zhong

    Article first published online : 26 JUN 2014, DOI: 10.1111/cbdd.12372

  17. Synthesis, Molecular Modeling, and Biological Evaluation of Novel 1, 3-Diphenyl-2-propen-1-one Based Pyrazolines as Anti-inflammatory Agents

    Chemical Biology & Drug Design

    Volume 85, Issue 6, June 2015, Pages: 729–742, Syed Nasir Abbas Bukhari, Xin Zhang, Ibrahim Jantan, Hai-Liang Zhu, Muhammad Wahab Amjad and Vijay H. Masand

    Article first published online : 15 NOV 2014, DOI: 10.1111/cbdd.12457

  18. Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery

    Chemical Biology & Drug Design

    Volume 81, Issue 1, January 2013, Pages: 148–165, Andrew G. Jamieson, Nicolas Boutard, David Sabatino and William D. Lubell

    Article first published online : 17 DEC 2012, DOI: 10.1111/cbdd.12042

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    Discovery of Staphylococcus aureus Sortase A Inhibitors Using Virtual Screening and the Relaxed Complex Scheme

    Chemical Biology & Drug Design

    Volume 82, Issue 4, October 2013, Pages: 418–428, Albert H. Chan, Jeff Wereszczynski, Brendan R. Amer, Sung Wook Yi, Michael E. Jung, J. Andrew McCammon and Robert T. Clubb

    Article first published online : 19 SEP 2013, DOI: 10.1111/cbdd.12167

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    Molecular Dynamics Simulations of Peptide Inhibitors Complexed With Trypanosoma cruzi Trypanothione Reductase

    Chemical Biology & Drug Design

    Volume 80, Issue 4, October 2012, Pages: 561–571, Samuel Silva Da Rocha Pita, Paulo Ricardo Batista, Magaly Girão Albuquerque and Pedro Geraldo Pascutti

    Article first published online : 18 JUL 2012, DOI: 10.1111/j.1747-0285.2012.01429.x