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There are 1316 results for: content related to: Synthesis and Biological Evaluation of [1,2,4]Triazolo[3,4-a]phthalazine and Tetrazolo[5,1-a]phthalazine Derivatives Bearing Substituted Benzylpiperazine Moieties as Positive Inotropic Agents

  1. Sulfated Small Molecules Targeting EBV in Burkitt Lymphoma: From In Silico Screening to the Evidence of In Vitro Effect on Viral Episomal DNA

    Chemical Biology & Drug Design

    Volume 81, Issue 5, May 2013, Pages: 631–644, Raquel T. Lima, Hugo Seca, Andreia Palmeira, Miguel X. Fernandes, Felipe Castro, Marta Correia-da-Silva, Maria S. J. Nascimento, Emília Sousa, Madalena Pinto and M. Helena Vasconcelos

    Article first published online : 4 APR 2013, DOI: 10.1111/cbdd.12109

  2. High-Throughput Screen of Natural Product Extracts in A Yeast Model of Polyglutamine Proteotoxicity

    Chemical Biology & Drug Design

    Volume 83, Issue 4, April 2014, Pages: 440–449, Gladis M. Walter, Avi Raveh, Sue-Ann Mok, Thomas J. McQuade, Carl J. Arevang, Pamela J. Schultz, Matthew C. Smith, Samuel Asare, Patricia G. Cruz, Susanne Wisen, Teatulohi Matainaho, David H. Sherman and Jason E. Gestwicki

    Article first published online : 18 MAR 2014, DOI: 10.1111/cbdd.12259

  3. Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors

    Chemical Biology & Drug Design

    Volume 81, Issue 6, June 2013, Pages: 695–706, Mari Gabrielsen, Karol Wołosewicz, Anna Zawadzka, Jerzy Kossakowski, Gabriel Nowak, Małgorzata Wolak, Katarzyna Stachowicz, Agata Siwek, Aina W. Ravna, Irina Kufareva, Lech Kozerski, Elżbieta Bednarek, Jerzy Sitkowski, Wojciech Bocian, Ruben Abagyan, Andrzej J. Bojarski, Ingebrigt Sylte and Zdzisław Chilmonczyk

    Article first published online : 11 APR 2013, DOI: 10.1111/cbdd.12116

  4. A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery

    Chemical Biology & Drug Design

    Meekyum Olivia Kim, Xinxin Feng, Ferran Feixas, Wei Zhu, Steffen Lindert, Shannon Bogue, William Sinko, César de Oliveira, Guodong Rao, Eric Oldfield and James Andrew McCammon

    Article first published online : 25 NOV 2014, DOI: 10.1111/cbdd.12463

  5. Penetratin and Derivatives Acting as Antibacterial Agents

    Chemical Biology & Drug Design

    Volume 82, Issue 2, August 2013, Pages: 167–177, Adriana D. Garro, Mónica S. Olivella, José A. Bombasaro, Beatriz Lima, Alejandro Tapia, Gabriela Feresin, Andras Perczel, Csaba Somlai, Botond Penke, Javier López Cascales, Ana M. Rodríguez and Ricardo D. Enriz

    Article first published online : 1 JUL 2013, DOI: 10.1111/cbdd.12143

  6. Identification of Dipeptidyl Peptidase IV Inhibitors: Virtual Screening, Synthesis and Biological Evaluation

    Chemical Biology & Drug Design

    Volume 84, Issue 3, September 2014, Pages: 364–377, Junhao Xing, Qing Li, Shengping Zhang, Haomiao Liu, Leilei Zhao, Haibo Cheng, Yuan Zhang, Jinpei Zhou and Huibin Zhang

    Article first published online : 14 MAY 2014, DOI: 10.1111/cbdd.12327

  7. Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein–Protein Interaction by a Scaffold-Hopping Approach

    Chemical Biology & Drug Design

    Andrey Zaytsev, Barry Dodd, Matteo Magnani, Chiara Ghiron, Bernard T. Golding, Roger J. Griffin, Junfeng Liu, Xiaohong Lu, Iolanda Micco, David R. Newell, Alessandro Padova, Graeme Robertson, John Lunec and Ian R. Hardcastle

    Article first published online : 19 DEC 2014, DOI: 10.1111/cbdd.12474

  8. Synthesis, Biological Evaluation, and Molecular Simulation of Chalcones and Aurones as Selective MAO-B Inhibitors

    Chemical Biology & Drug Design

    Nicole Morales-Camilo, Cristian O. Salas, Claudia Sanhueza, Christian Espinosa-Bustos, Silvia Sepúlveda-Boza, Miguel Reyes-Parada, Fernando Gonzalez-Nilo, Marcos Caroli-Rezende and Angélica Fierro

    Article first published online : 15 NOV 2014, DOI: 10.1111/cbdd.12458

  9. Potassium Channels: Structures, Diseases, and Modulators

    Chemical Biology & Drug Design

    Volume 83, Issue 1, January 2014, Pages: 1–26, Chuan Tian, Ruixin Zhu, Lixin Zhu, Tianyi Qiu, Zhiwei Cao and Tingguo Kang

    Article first published online : 23 DEC 2013, DOI: 10.1111/cbdd.12237

  10. Identification of Novel Selective Lysine-Specific Demethylase 1 (LSD1) Inhibitors Using a Pharmacophore-Based Virtual Screening Combined with Docking

    Chemical Biology & Drug Design

    Chen Zhou, Di Kang, Yungen Xu, Luyong Zhang and Xiaoming Zha

    Article first published online : 22 DEC 2014, DOI: 10.1111/cbdd.12461

  11. In silico Target Fishing for the Potential Targets and Molecular Mechanisms of Baicalein as an Antiparkinsonian Agent: Discovery of the Protective Effects on NMDA Receptor-Mediated Neurotoxicity

    Chemical Biology & Drug Design

    Volume 81, Issue 6, June 2013, Pages: 675–687, Li Gao, Jian-Song Fang, Xiao-Yu Bai, Dan Zhou, Yi-Tao Wang, Ai-Lin Liu and Guan-Hua Du

    Article first published online : 25 MAY 2013, DOI: 10.1111/cbdd.12127

  12. N-substituted Piperazinopyridylsteroid Derivatives as Abiraterone Analogues Inhibit Growth and Induce Pro-apoptosis in Human Hormone-independent Prostate Cancer Cell Lines

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 620–629, Dominique Brossard, Ying Zhang, Shozeb M. Haider, Miriam Sgobba, Mohamed Khalid, Rémi Legay, Martine Duterque-Coquillaud, Philippe Galera, Sylvain Rault, Patrick Dallemagne, Safa Moslemi and Laïla El Kihel

    Article first published online : 16 OCT 2013, DOI: 10.1111/cbdd.12195

  13. Does Aluminium Bind to Histidine? An NMR Investigation of Amyloid β12 and Amyloid β16 Fragments

    Chemical Biology & Drug Design

    Volume 82, Issue 1, July 2013, Pages: 48–59, Priya Narayan, Bankala Krishnarjuna, Vinaya Vishwanathan, Dasappa Jagadeesh Kumar, Sudhir Babu, Krishna Venkatachala Ramanathan, Kalpathy Ramaier Katchap Easwaran, Holenarasipur GunduRao Nagendra and Srinivasarao Raghothama

    Article first published online : 21 JUN 2013, DOI: 10.1111/cbdd.12129

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    Discovery of Staphylococcus aureus Sortase A Inhibitors Using Virtual Screening and the Relaxed Complex Scheme

    Chemical Biology & Drug Design

    Volume 82, Issue 4, October 2013, Pages: 418–428, Albert H. Chan, Jeff Wereszczynski, Brendan R. Amer, Sung Wook Yi, Michael E. Jung, J. Andrew McCammon and Robert T. Clubb

    Article first published online : 19 SEP 2013, DOI: 10.1111/cbdd.12167

  15. Design, Synthesis, and Preliminary Cardioprotective Effect Evaluation of Danshensu Derivatives

    Chemical Biology & Drug Design

    Volume 84, Issue 3, September 2014, Pages: 282–291, Qingbin Cui, Yonghong Chen, Mingjuan Zhang, Luchen Shan, Yewei Sun, Pei Yu, Gaoxiao Zhang, Dingyuan Wang, Zengchao Zhao, Qian Xu, Benhong Xu and Yuqiang Wang

    Article first published online : 1 JUL 2014, DOI: 10.1111/cbdd.12312

  16. Identification of Nucleoside Analogs as Inducers of Neuronal Differentiation in a Human Reporter Cell Line and Adult Stem Cells

    Chemical Biology & Drug Design

    Katharina Raasch, Edith Malecki, Maria Siemann, Malayko M. Martinez, Jürgen J. Heinisch, Janine Müller, Lidia Bakota, Christian Kaltschmidt, Barbara Kaltschmidt, Helmut Rosemeyer and Roland Brandt

    Article first published online : 12 JAN 2015, DOI: 10.1111/cbdd.12488

  17. Exploring the Ligand Recognition Properties of the Human Vasopressin V1a Receptor Using QSAR and Molecular Modeling Studies

    Chemical Biology & Drug Design

    Volume 83, Issue 2, February 2014, Pages: 207–223, Martha C. Contreras-Romo, Marlet Martínez-Archundia, Omar Deeb, Magdalena J. Ślusarz, Gema Ramírez-Salinas, Ramón Garduño-Juárez, Andrés Quintanar-Stephano, Guillermo Ramírez-Galicia and José Correa-Basurto

    Article first published online : 26 DEC 2013, DOI: 10.1111/cbdd.12229

  18. A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region

    Chemical Biology & Drug Design

    Jamie A. Moroco, Matthew P. Baumgartner, Heather L. Rust, Hwan Geun Choi, Wooyoung Hur, Nathanael S. Gray, Carlos J. Camacho and Thomas E. Smithgall

    Article first published online : 28 NOV 2014, DOI: 10.1111/cbdd.12473

  19. Novel Peptidomimetics for Inhibition of HER2:HER3 Heterodimerization in HER2-Positive Breast Cancer

    Chemical Biology & Drug Design

    Shanthi Kanthala, Sashikanth Banappagari, Ameya Gokhale, Yong-Yu Liu, Gu Xin, Yunfeng Zhao and Seetharama Jois

    Article first published online : 6 NOV 2014, DOI: 10.1111/cbdd.12453

  20. CD44-Targeted Docetaxel Conjugate for Cancer Cells and Cancer Stem-Like Cells: A Novel Hyaluronic Acid-Based Drug Delivery System

    Chemical Biology & Drug Design

    Volume 83, Issue 6, June 2014, Pages: 741–752, Navid Goodarzi, Mohammad H. Ghahremani, Mohsen Amini, Fatemeh Atyabi, Seyed N. Ostad, Nazanin Shabani Ravari, Navid Nateghian and Rassoul Dinarvand

    Article first published online : 13 MAR 2014, DOI: 10.1111/cbdd.12288