Search Results

There are 9580 results for: content related to: Evaluation of Coumarin and Neoflavone Derivatives as HCV NS 5 B Polymerase Inhibitors

  1. Combined 3D-QSAR, Molecular Docking, Molecular Dynamics Simulation, and Binding Free Energy Calculation Studies on the 5-Hydroxy-2H-Pyridazin-3-One Derivatives as HCV NS5B Polymerase Inhibitors

    Chemical Biology & Drug Design

    Volume 83, Issue 1, January 2014, Pages: 89–105, Haijing Yu, Yu Fang, Xia Lu, Yongjuan Liu and Huabei Zhang

    Version of Record online : 4 OCT 2013, DOI: 10.1111/cbdd.12203

  2. Monoclonal antibody recognizing N-terminal epitope of hepatitis C virus nonstructural 5B inhibits viral RNA replication

    Journal of Viral Hepatitis

    Volume 15, Issue 4, April 2008, Pages: 305–313, S. M. Kang, S. H. Choi, C. Y. Park, M. H. Kim, T. K. Kim, J. M. Park, M. S. Koh, H. J. Kang and S. B. Hwang

    Version of Record online : 12 DEC 2007, DOI: 10.1111/j.1365-2893.2007.00945.x

  3. You have free access to this content
    Direct interaction between α-actinin and hepatitis C virus NS5B

    FEBS Letters

    Volume 554, Issue 3, November 20, 2003, Pages: 289–294, Shuiyun Lan, Hua Wang, Hong Jiang, Hongxia Mao, Xiaoying Liu, Xiaonan Zhang, Yunwen Hu, Li Xiang and Zhenghong Yuan

    Version of Record online : 21 OCT 2003, DOI: 10.1016/S0014-5793(03)01163-3

  4. You have free access to this content
    C-Src is required for complex formation between the hepatitis C virus–encoded proteins NS5A and NS5B: A prerequisite for replication

    Hepatology

    Volume 53, Issue 4, April 2011, Pages: 1127–1136, Andreas Pfannkuche, Katrin Büther, Juliane Karthe, Marion Poenisch, Ralf Bartenschlager, Mirko Trilling, Hartmut Hengel, Dieter Willbold, Dieter Häussinger and Johannes Georg Bode

    Version of Record online : 7 APR 2011, DOI: 10.1002/hep.24214

  5. Discovery of N-Arylalkyl-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-carboxamide Derivatives as HCV NS5B Polymerase Inhibitors

    ChemMedChem

    Volume 7, Issue 5, May 2012, Pages: 850–860, Dr. Ravindra Ramesh Deore, Prof. Grace Shiahuy Chen, Dr. Pei-Teh Chang, Ting-Rong Chern, Dr. Shin-Yu Lai, Ming-Hsieh Chuang, Prof. Jung-Hsin Lin, Prof. Fan-Lu Kung, Prof. Chien-Shu Chen, Dr. Chun-Tang Chiou and Prof. Ji-Wang Chern

    Version of Record online : 1 MAR 2012, DOI: 10.1002/cmdc.201200058

  6. You have free access to this content
    Specific interaction between the classical swine fever virus NS5B protein and the viral genome

    European Journal of Biochemistry

    Volume 271, Issue 19, October 2004, Pages: 3888–3896, Ming Xiao, Jufang Gao, Wei Wang, Yujing Wang, Jun Chen, Jiakuan Chen and Bo Li

    Version of Record online : 6 SEP 2004, DOI: 10.1111/j.1432-1033.2004.04325.x

  7. Natural prevalence of hepatitis C virus (HCV) variants resistant to protease and polymerase inhibitors in patients infected with HCV genotype 1 in Tunisia

    Journal of Medical Virology

    Volume 86, Issue 8, August 2014, Pages: 1350–1359, Jameleddine Aissa Larousse, Pascale Trimoulet, Patricia Recordon-Pinson, Jennnifer Papuchon, Mohamed Mssadak Azzouz, Nabyl Ben Mami, Imed Cheikh, Henda Triki and Hervé Fleury

    Version of Record online : 24 APR 2014, DOI: 10.1002/jmv.23958

  8. Site-specific cleavage of HCV genomic RNA and its cloned core and NS5B genes by DNAzyme

    Journal of Gastroenterology and Hepatology

    Volume 24, Issue 5, May 2009, Pages: 872–878, Deepak Kumar, Indrajit Chaudhury, Premashis Kar and Rakha H Das

    Version of Record online : 9 FEB 2009, DOI: 10.1111/j.1440-1746.2008.05717.x

  9. You have free access to this content
    Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

    Hepatology

    Volume 50, Issue 6, December 2009, Pages: 1727–1737, Yasuhiro Itsui, Naoya Sakamoto, Sei Kakinuma, Mina Nakagawa, Yuko Sekine-Osajima, Megumi Tasaka-Fujita, Yuki Nishimura-Sakurai, Gouki Suda, Yuko Karakama, Kako Mishima, Machi Yamamoto, Takako Watanabe, Mayumi Ueyama, Yusuke Funaoka, Seishin Azuma and Mamoru Watanabe

    Version of Record online : 5 AUG 2009, DOI: 10.1002/hep.23195

  10. Thumb inhibitor binding eliminates functionally important dynamics in the hepatitis C virus RNA polymerase

    Proteins: Structure, Function, and Bioinformatics

    Volume 81, Issue 1, January 2013, Pages: 40–52, Brittny C. Davis and Ian F. Thorpe

    Version of Record online : 15 SEP 2012, DOI: 10.1002/prot.24154

  11. You have free access to this content
    Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A

    Hepatology

    Volume 50, Issue 1, July 2009, Pages: 25–33, Zhe Liu, John M. Robida, Sreedhar Chinnaswamy, Guanghui Yi, Jason M. Robotham, Heather B. Nelson, Andre Irsigler, C. Cheng Kao and Hengli Tang

    Version of Record online : 6 APR 2009, DOI: 10.1002/hep.22987

  12. You have free access to this content
    Sensitivity of hepatitis C virus to cyclosporine A depends on nonstructural proteins NS5A and NS5B

    Hepatology

    Volume 46, Issue 4, October 2007, Pages: 1026–1033, Fiona Fernandes, Daniel S. Poole, Spencer Hoover, Rannveig Middleton, Adin-Cristian Andrei, Justin Gerstner and Rob Striker

    Version of Record online : 28 JUN 2007, DOI: 10.1002/hep.21809

  13. You have free access to this content
    Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3′-end of virus minus-strand RNA

    The FEBS Journal

    Volume 272, Issue 15, August 2005, Pages: 3872–3886, Thérèse Astier-Gin, Pantxika Bellecave, Simon Litvak and Michel Ventura

    Version of Record online : 19 JUL 2005, DOI: 10.1111/j.1742-4658.2005.04804.x

  14. Effective epitope identification employing phylogenetic, mutational variability, sequence entropy, and correlated mutation analysis targeting NS5B protein of hepatitis C virus: from bioinformatics to therapeutics

    Journal of Molecular Recognition

    Volume 28, Issue 8, August 2015, Pages: 492–505, Rohan J. Meshram and Rajesh N. Gacche

    Version of Record online : 27 FEB 2015, DOI: 10.1002/jmr.2466

  15. You have free access to this content
    Isoform-specific interaction of pyruvate kinase with hepatitis C virus NS5B

    FEBS Letters

    Volume 582, Issue 15, June 25, 2008, Pages: 2155–2160, Xiaoyun Wu, You Zhou, Ke Zhang, Qingzhen Liu and Deyin Guo

    Version of Record online : 2 JUN 2008, DOI: 10.1016/j.febslet.2008.05.033

  16. You have free access to this content
    Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by cis-acting RNA elements and trans-acting viral factors

    The FEBS Journal

    Volume 275, Issue 16, August 2008, Pages: 4179–4197, Sofia Lourenço, Fleur Costa, Béatrice Débarges, Thibault Andrieu and Annie Cahour

    Version of Record online : 11 JUL 2008, DOI: 10.1111/j.1742-4658.2008.06566.x

  17. Analysis of a non-structural gene reveals evidence of possible hepatitis C virus (HCV) compartmentalization

    Journal of Medical Virology

    Volume 84, Issue 2, February 2012, Pages: 242–252, Jason T. Blackard, Gang Ma, Jeffrey A. Welge, Christina M. Martin, Kenneth E. Sherman, Lynn E. Taylor, Kenneth H. Mayer and Denise J. Jamieson

    Version of Record online : 14 DEC 2011, DOI: 10.1002/jmv.22269

  18. Prevalence and characteristics of naturally occurring sofosbuvir resistance-associated variants in patients with hepatitis C virus genotype 1b infection

    Hepatology Research

    Jun Ito, Goki Suda, Yoshiya Yamamoto, Atsushi Nagasaka, Ken Furuya, Kenichi Kumagai, Hideaki Kikuchi, Takuto Miyagishima, Tomoe Kobayashi, Megumi Kimura, Kazushi Yamasaki, Machiko Umemura, Takaaki Izumi, Seiji Tsunematsu, Fumiyuki Sato, Yoko Tsukuda, Katsumi Terashita, Masato Nakai, Takuya Sho, Mitsuteru Natsuizaka, Kenichi Morikawa, Koji Ogawa, Naoya Sakamoto and for the NORTE Study Group

    Version of Record online : 8 APR 2016, DOI: 10.1111/hepr.12685

  19. You have free access to this content
    HCV RNA-dependent RNA polymerase replicates in vitro the 3′ terminal region of the minus-strand viral RNA more efficiently than the 3′ terminal region of the plus RNA

    European Journal of Biochemistry

    Volume 268, Issue 22, November 2001, Pages: 5857–5867, Sandrine Reigadas, Michel Ventura, Leila Sarih-Cottin, Michel Castroviejo, Simon Litvak and Thérèse Astier-Gin

    Version of Record online : 20 DEC 2001, DOI: 10.1046/j.0014-2956.2001.02532.x

  20. Mutations in the NS5B region of the hepatitis C virus genome correlate with clinical outcomes of interferon-alpha plus ribavirin combination therapy

    Journal of Gastroenterology and Hepatology

    Volume 20, Issue 9, September 2005, Pages: 1401–1409, KOSEI HAMANO, NAOYA SAKAMOTO, NOBUYUKI ENOMOTO, NAMIKI IZUMI, YASUHIRO ASAHINA, MASAYUKI KUROSAKI, ERI UEDA, YOKO TANABE, SHINYA MAEKAWA, JUN ITAKURA, HIDEKI WATANABE, SEI KAKINUMA and MAMORU WATANABE

    Version of Record online : 19 JUL 2005, DOI: 10.1111/j.1440-1746.2005.04024.x