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There are 8196 results for: content related to: Crystallographic Fragment-Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease

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    Cantharidin-Based Small Molecules as Potential Therapeutic Agents

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 477–499, Carlos E. Puerto Galvis, Leonor Y. Vargas Méndez and Vladimir V. Kouznetsov

    Article first published online : 8 AUG 2013, DOI: 10.1111/cbdd.12180

  2. Homology Modeling, Docking Studies and Molecular Dynamic Simulations Using Graphical Processing Unit Architecture to Probe the Type-11 Phosphodiesterase Catalytic Site: A Computational Approach for the Rational Design of Selective Inhibitors

    Chemical Biology & Drug Design

    Volume 82, Issue 6, December 2013, Pages: 718–731, Elena Cichero, Pasqualina D'Ursi, Marco Moscatelli, Olga Bruno, Alessandro Orro, Chiara Rotolo, Luciano Milanesi and Paola Fossa

    Article first published online : 26 AUG 2013, DOI: 10.1111/cbdd.12193

  3. Further Insights Into the Pharmacology of the Human Trace Amine-Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach

    Chemical Biology & Drug Design

    Elena Cichero, Stefano Espinoza, Silvia Franchini, Sara Guariento, Livio Brasili, Raul R. Gainetdinov and Paola Fossa

    Article first published online : 29 JUN 2014, DOI: 10.1111/cbdd.12367

  4. Synthesis, Antibacterial Activities, and 3D-QSAR of Sulfone Derivatives Containing 1, 3, 4-Oxadiazole Moiety

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 546–556, Pei Li, Juan Yin, Weiming Xu, Jian Wu, Ming He, Deyu Hu, Song Yang and Baoan Song

    Article first published online : 21 AUG 2013, DOI: 10.1111/cbdd.12181

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    Potassium Channels: Structures, Diseases, and Modulators

    Chemical Biology & Drug Design

    Volume 83, Issue 1, January 2014, Pages: 1–26, Chuan Tian, Ruixin Zhu, Lixin Zhu, Tianyi Qiu, Zhiwei Cao and Tingguo Kang

    Article first published online : 23 DEC 2013, DOI: 10.1111/cbdd.12237

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    1,3,4-Thiadiazole and its Derivatives: A Review on Recent Progress in Biological Activities

    Chemical Biology & Drug Design

    Volume 81, Issue 5, May 2013, Pages: 557–576, Abhishek Kumar Jain, Simant Sharma, Ankur Vaidya, Veerasamy Ravichandran and Ram Kishore Agrawal

    Article first published online : 24 APR 2013, DOI: 10.1111/cbdd.12125

  7. Differential Modulation in Binding of Ketoprofen to Bovine Serum Albumin in the Presence and Absence of Surfactants: Spectroscopic and Calorimetric Insights

    Chemical Biology & Drug Design

    Volume 82, Issue 1, July 2013, Pages: 81–98, Pinaki P. Misra and Nand Kishore

    Article first published online : 21 JUN 2013, DOI: 10.1111/cbdd.12136

  8. Lead Optimization on Conventional Non-Steroidal Anti-Inflammatory Drugs: An Approach to Reduce Gastrointestinal Toxicity

    Chemical Biology & Drug Design

    Volume 84, Issue 1, July 2014, Pages: 1–23, Tamanna Narsinghani and Rajesh Sharma

    Article first published online : 13 MAR 2014, DOI: 10.1111/cbdd.12292

  9. Insight into the Structural Features of Pyrazolopyrimidine- and Pyrazolopyridine-based B-RafV600E Kinase Inhibitors by Computational Explorations

    Chemical Biology & Drug Design

    Volume 83, Issue 6, June 2014, Pages: 643–655, Yan Li, Chunxiao Han, Jinghui Wang, Yinfeng Yang, Jingxiao Zhang, Shuwei Zhang and Ling Yang

    Article first published online : 20 MAR 2014, DOI: 10.1111/cbdd.12276

  10. In silico Characterization of an Atypical MAPK Phosphatase of Plasmodium falciparum as a Suitable Target for Drug Discovery

    Chemical Biology & Drug Design

    Volume 84, Issue 2, August 2014, Pages: 158–168, Christopher O. Campbell, Daniel N. Santiago, Wayne C. Guida, Roman Manetsch and John H. Adams

    Article first published online : 12 MAY 2014, DOI: 10.1111/cbdd.12315

  11. Synthesis and in vitro Evaluation of 1,2,4-Triazolo[1,5-a][1,3,5]triazine Derivatives as Thymidine Phosphorylase Inhibitors

    Chemical Biology & Drug Design

    Volume 82, Issue 3, September 2013, Pages: 351–360, Hriday Bera, Anton V. Dolzhenko, Lingyi Sun, Sayan Dutta Gupta and Wai-Keung Chui

    Article first published online : 22 AUG 2013, DOI: 10.1111/cbdd.12171

  12. Theoretical Characterization of Galanin Receptor Type 3 (Gal3) and Its Interaction with Agonist (GALANIN) and Antagonists (SNAP 37889 and SNAP 398299): An In Silico Analysis

    Chemical Biology & Drug Design

    Volume 81, Issue 6, June 2013, Pages: 757–774, Gugan Kothandan, Changdev G. Gadhe and Seung J. Cho

    Article first published online : 17 APR 2013, DOI: 10.1111/cbdd.12128

  13. Synthesis, Molecular Docking, and Biological Evaluation of Some Novel Hydrazones and Pyrazole Derivatives as Anti-inflammatory Agents

    Chemical Biology & Drug Design

    Volume 84, Issue 4, October 2014, Pages: 473–488, Khaled O. Mohammed and Yassin M. Nissan

    Article first published online : 3 JUN 2014, DOI: 10.1111/cbdd.12336

  14. Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors

    Chemical Biology & Drug Design

    Volume 83, Issue 4, April 2014, Pages: 498–506, Variam U. Jeankumar, Reshma Alokam, Jonnalagadda P. Sridevi, Priyanka Suryadevara, Siddharth S. Matikonda, Santosh Peddi, Seedarala Sahithi, Mallika Alvala, Perumal Yogeeswari and Dharmarajan Sriram

    Article first published online : 18 MAR 2014, DOI: 10.1111/cbdd.12265

  15. Synthesis of Ranolazine Derivatives Containing the (1S,4S)-2,5-Diazabicyclo[2.2.1]Heptane Moiety and Their Evaluation as Vasodilating Agents

    Chemical Biology & Drug Design

    Volume 83, Issue 6, June 2014, Pages: 710–720, Manuel López-Ortiz, Ivan Monsalvo, Patricia Demare, Cristina Paredes, Dieter Mascher, Carlos Hernández, Marcos Hernández and Ignacio Regla

    Article first published online : 14 MAY 2014, DOI: 10.1111/cbdd.12285

  16. Design, Synthesis, and Preliminary Cardioprotective Effect Evaluation of Danshensu Derivatives

    Chemical Biology & Drug Design

    Volume 84, Issue 3, September 2014, Pages: 282–291, Qingbin Cui, Yonghong Chen, Mingjuan Zhang, Luchen Shan, Yewei Sun, Pei Yu, Gaoxiao Zhang, Dingyuan Wang, Zengchao Zhao, Qian Xu, Benhong Xu and Yuqiang Wang

    Article first published online : 1 JUL 2014, DOI: 10.1111/cbdd.12312

  17. New Force Field on Modeling Intrinsically Disordered Proteins

    Chemical Biology & Drug Design

    Volume 84, Issue 3, September 2014, Pages: 253–269, Wei Wang, Wei Ye, Cheng Jiang, Ray Luo and Hai-Feng Chen

    Article first published online : 1 JUL 2014, DOI: 10.1111/cbdd.12314

  18. Hologram Quantitative Structure Activity Relationship, Docking, and Molecular Dynamics Studies of Inhibitors for CXCR4

    Chemical Biology & Drug Design

    Chongqian Zhang, Chunmiao Du, Zhiwei Feng, Jingyu Zhu and Youyong Li

    Article first published online : 10 JUL 2014, DOI: 10.1111/cbdd.12377

  19. Synthesis and Evaluation of a New Series of 3,5-bis((5-bromo-6-methyl-2-t-aminopyrimidin-4-yl)thio)-4H-1,2,4-triazol-4-amines and their Cyclized Products ‘Pyrimidinylthio Pyrimidotriazolothiadiazines’ as 15- Lipo-Oxygenase Inhibitors

    Chemical Biology & Drug Design

    Tayebe Asghari, Mehdi Bakavoli, Mohammad Rahimizadeh, Hossein Eshghi, Sattar Saberi, Azam Karimian, Farzin Hadizadeh and Moreteza Ghandadi

    Article first published online : 10 JUL 2014, DOI: 10.1111/cbdd.12375

  20. Exploring the Ligand Recognition Properties of the Human Vasopressin V1a Receptor Using QSAR and Molecular Modeling Studies

    Chemical Biology & Drug Design

    Volume 83, Issue 2, February 2014, Pages: 207–223, Martha C. Contreras-Romo, Marlet Martínez-Archundia, Omar Deeb, Magdalena J. Ślusarz, Gema Ramírez-Salinas, Ramón Garduño-Juárez, Andrés Quintanar-Stephano, Guillermo Ramírez-Galicia and José Correa-Basurto

    Article first published online : 26 DEC 2013, DOI: 10.1111/cbdd.12229