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There are 21487 results for: content related to: Discovery of Synthetic Leishmania Inhibitors by Screening of a 2-Arylbenzothiophene Library

  1. Exploring the Ligand Recognition Properties of the Human Vasopressin V1a Receptor Using QSAR and Molecular Modeling Studies

    Chemical Biology & Drug Design

    Volume 83, Issue 2, February 2014, Pages: 207–223, Martha C. Contreras-Romo, Marlet Martínez-Archundia, Omar Deeb, Magdalena J. Ślusarz, Gema Ramírez-Salinas, Ramón Garduño-Juárez, Andrés Quintanar-Stephano, Guillermo Ramírez-Galicia and José Correa-Basurto

    Article first published online : 26 DEC 2013, DOI: 10.1111/cbdd.12229

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    Cantharidin-Based Small Molecules as Potential Therapeutic Agents

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 477–499, Carlos E. Puerto Galvis, Leonor Y. Vargas Méndez and Vladimir V. Kouznetsov

    Article first published online : 8 AUG 2013, DOI: 10.1111/cbdd.12180

  3. Repurposing Human PDE4 Inhibitors for Neglected Tropical Diseases. Evaluation of Analogs of the Human PDE4 Inhibitor GSK-256066 as Inhibitors of PDEB1 of Trypanosoma brucei

    Chemical Biology & Drug Design

    Stefan O. Ochiana, Nicholas D. Bland, Luca Settimo, Robert K. Campbell and Michael P. Pollastri

    Article first published online : 18 NOV 2014, DOI: 10.1111/cbdd.12443

  4. Homology Modeling, Docking Studies and Molecular Dynamic Simulations Using Graphical Processing Unit Architecture to Probe the Type-11 Phosphodiesterase Catalytic Site: A Computational Approach for the Rational Design of Selective Inhibitors

    Chemical Biology & Drug Design

    Volume 82, Issue 6, December 2013, Pages: 718–731, Elena Cichero, Pasqualina D'Ursi, Marco Moscatelli, Olga Bruno, Alessandro Orro, Chiara Rotolo, Luciano Milanesi and Paola Fossa

    Article first published online : 26 AUG 2013, DOI: 10.1111/cbdd.12193

  5. In silico Characterization of an Atypical MAPK Phosphatase of Plasmodium falciparum as a Suitable Target for Drug Discovery

    Chemical Biology & Drug Design

    Volume 84, Issue 2, August 2014, Pages: 158–168, Christopher O. Campbell, Daniel N. Santiago, Wayne C. Guida, Roman Manetsch and John H. Adams

    Article first published online : 12 MAY 2014, DOI: 10.1111/cbdd.12315

  6. Design, Synthesis, and Preliminary Cardioprotective Effect Evaluation of Danshensu Derivatives

    Chemical Biology & Drug Design

    Volume 84, Issue 3, September 2014, Pages: 282–291, Qingbin Cui, Yonghong Chen, Mingjuan Zhang, Luchen Shan, Yewei Sun, Pei Yu, Gaoxiao Zhang, Dingyuan Wang, Zengchao Zhao, Qian Xu, Benhong Xu and Yuqiang Wang

    Article first published online : 1 JUL 2014, DOI: 10.1111/cbdd.12312

  7. Further Insights Into the Pharmacology of the Human Trace Amine-Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach

    Chemical Biology & Drug Design

    Volume 84, Issue 6, December 2014, Pages: 712–720, Elena Cichero, Stefano Espinoza, Silvia Franchini, Sara Guariento, Livio Brasili, Raul R. Gainetdinov and Paola Fossa

    Article first published online : 29 JUN 2014, DOI: 10.1111/cbdd.12367

  8. Insight into the Structural Features of Pyrazolopyrimidine- and Pyrazolopyridine-based B-RafV600E Kinase Inhibitors by Computational Explorations

    Chemical Biology & Drug Design

    Volume 83, Issue 6, June 2014, Pages: 643–655, Yan Li, Chunxiao Han, Jinghui Wang, Yinfeng Yang, Jingxiao Zhang, Shuwei Zhang and Ling Yang

    Article first published online : 20 MAR 2014, DOI: 10.1111/cbdd.12276

  9. Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors

    Chemical Biology & Drug Design

    Volume 83, Issue 4, April 2014, Pages: 498–506, Variam U. Jeankumar, Reshma Alokam, Jonnalagadda P. Sridevi, Priyanka Suryadevara, Siddharth S. Matikonda, Santosh Peddi, Seedarala Sahithi, Mallika Alvala, Perumal Yogeeswari and Dharmarajan Sriram

    Article first published online : 18 MAR 2014, DOI: 10.1111/cbdd.12265

  10. Design, Synthesis and Biological Evaluation of Pazopanib Derivatives as Antitumor Agents

    Chemical Biology & Drug Design

    Volume 83, Issue 3, March 2014, Pages: 306–316, Yuping Jia, Jian Zhang, Jinhong Feng, Fuming Xu, Huili Pan and Wenfang Xu

    Article first published online : 1 FEB 2014, DOI: 10.1111/cbdd.12243

  11. Crystallographic Fragment-Based Drug Discovery: Use of a Brominated Fragment Library Targeting HIV Protease

    Chemical Biology & Drug Design

    Volume 83, Issue 2, February 2014, Pages: 141–148, Theresa Tiefenbrunn, Stefano Forli, Meaghan Happer, Ana Gonzalez, Yingssu Tsai, Michael Soltis, John H. Elder, Arthur J. Olson and Charles D. Stout

    Article first published online : 30 OCT 2013, DOI: 10.1111/cbdd.12227

  12. Synthesis and 3D-QSAR Analysis of 2-Chloroquinoline Derivatives as H37RV MTB Inhibitors

    Chemical Biology & Drug Design

    Volume 82, Issue 6, December 2013, Pages: 669–684, Ranjan C. Khunt, Vijay M. Khedkar and Evans C. Coutinho

    Article first published online : 25 NOV 2013, DOI: 10.1111/cbdd.12178

  13. Synthesis and Evaluation of a New Series of 3,5-bis((5-bromo-6-methyl-2-t-aminopyrimidin-4-yl)thio)-4H-1,2,4-triazol-4-amines and their Cyclized Products ‘Pyrimidinylthio Pyrimidotriazolothiadiazines’ as 15- Lipo-Oxygenase Inhibitors

    Chemical Biology & Drug Design

    Volume 85, Issue 2, February 2015, Pages: 216–224, Tayebe Asghari, Mehdi Bakavoli, Mohammad Rahimizadeh, Hossein Eshghi, Sattar Saberi, Azam Karimian, Farzin Hadizadeh and Moreteza Ghandadi

    Article first published online : 10 JUL 2014, DOI: 10.1111/cbdd.12375

  14. Synthesis, Antibacterial Activities, and 3D-QSAR of Sulfone Derivatives Containing 1, 3, 4-Oxadiazole Moiety

    Chemical Biology & Drug Design

    Volume 82, Issue 5, November 2013, Pages: 546–556, Pei Li, Juan Yin, Weiming Xu, Jian Wu, Ming He, Deyu Hu, Song Yang and Baoan Song

    Article first published online : 21 AUG 2013, DOI: 10.1111/cbdd.12181

  15. Structural Factors Affecting Cytotoxic Activity of (E)-1-(Benzo[][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one Derivatives

    Chemical Biology & Drug Design

    Volume 84, Issue 1, July 2014, Pages: 86–91, Marek T. Konieczny, Anita Bułakowska, Justyna Polak, Danuta Pirska, Wojciech Konieczny, Patrycja Gryń, Andrzej Skladanowski, Michał Sabisz, Krzysztof Lemke, Anna Pieczykolan, Marlena Gałązka, Katarzyna Wiciejowska and Joanna Wietrzyk

    Article first published online : 28 FEB 2014, DOI: 10.1111/cbdd.12296

  16. Design and Synthesis of a New Class of 4-Aminoquinolinyl- and 9-Anilinoacridinyl Schiff Base Hydrazones as Potent Antimalarial Agents

    Chemical Biology & Drug Design

    Volume 84, Issue 2, August 2014, Pages: 175–181, Moni Sharma, Kuldeep Chauhan, Rajeev K. Srivastava, Shiv V. Singh, Kumkum Srivastava, Jitendra K. Saxena, Sunil K. Puri and Prem M. S. Chauhan

    Article first published online : 13 MAR 2014, DOI: 10.1111/cbdd.12289

  17. Derivatives Form Better Lipoxygenase Inhibitors than Piperine: In Vitro and In Silico Study

    Chemical Biology & Drug Design

    Muringayil J. Tomy, Chelankara S. Sharanya, Kalarickal V. Dileep, Shankar Prasanth, Abudulhameed Sabu, Chittalakkottu Sadasivan and Madathilkovilakathu Haridas

    Article first published online : 17 NOV 2014, DOI: 10.1111/cbdd.12455

  18. Discovery of Novel Secretory Phospholipase A2 Inhibitors Using Virtual Screen

    Chemical Biology & Drug Design

    Volume 84, Issue 2, August 2014, Pages: 216–222, Shunchen Qiu, Fangjin Chen, Ying Liu and Luhua Lai

    Article first published online : 1 JUL 2014, DOI: 10.1111/cbdd.12307

  19. Design and Biological Evaluation of Furan/Pyrrole/Thiophene-2-carboxamide Derivatives as Efficient DNA GyraseB Inhibitors of Staphylococcus aureus

    Chemical Biology & Drug Design

    Renuka Janupally, Bhramam Medepi, Parthiban Brindha Devi, Priyanka Suryadevara, Variam Ullas Jeankumar, Pushkar Kulkarni, Perumal Yogeeswari and Dharmarajan Sriram

    Article first published online : 19 FEB 2015, DOI: 10.1111/cbdd.12529

  20. Structure-Based Evaluation of C5 Derivatives in the Catechol Diether Series Targeting HIV-1 Reverse Transcriptase

    Chemical Biology & Drug Design

    Volume 83, Issue 5, May 2014, Pages: 541–549, Kathleen M. Frey, William T. Gray, Krasimir A. Spasov, Mariela Bollini, Ricardo Gallardo-Macias, William L. Jorgensen and Karen S. Anderson

    Article first published online : 14 MAR 2014, DOI: 10.1111/cbdd.12266