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There are 15350 results for: content related to: Induction of autoimmune diabetes in non-obese diabetic mice requires interleukin-21-dependent activation of autoreactive CD 8 + T cells

  1. Interleukin-21 suppresses the differentiation and functions of T helper 2 cells


    Volume 144, Issue 4, April 2015, Pages: 668–676, Pin-Yi Lin, Hsiao-Yu Jen, Bor-Luen Chiang, Fuu Sheu and Ya-Hui Chuang

    Article first published online : 9 MAR 2015, DOI: 10.1111/imm.12419

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    IL-21: roles in immunopathology and cancer therapy

    Tissue Antigens

    Volume 74, Issue 6, December 2009, Pages: 467–479, H. Søndergaard and K. Skak

    Article first published online : 21 OCT 2009, DOI: 10.1111/j.1399-0039.2009.01382.x

  3. IL-21 receptor signalling partially mediates Th2-mediated allergic airway responses

    Clinical & Experimental Allergy

    Volume 44, Issue 7, July 2014, Pages: 976–985, S. Lajoie, I. Lewkowich, N. S. Herman, A. Sproles, J. T. Pesce, T. A. Wynn, M. J. Grusby, Q. Hamid and M. Wills-Karp

    Article first published online : 23 JUN 2014, DOI: 10.1111/cea.12341

  4. Elevated frequencies of CD4+IL-21+T, CD4+IL-21R+T and IL-21+Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis

    International Journal of Rheumatic Diseases

    Ling Lei, Zhi-Yi He, Cheng Zhao, Xue-Jiao Sun and Xiao-Ning Zhong

    Article first published online : 25 DEC 2014, DOI: 10.1111/1756-185X.12522

  5. Involvement of interleukin-21 in the pathophysiology of aplastic anemia

    European Journal of Haematology

    Volume 95, Issue 1, July 2015, Pages: 44–51, Jizhou Zhang, Qingqing Wu, Jun Shi, Meili Ge, Xingxin Li, Yingqi Shao, Jianfeng Yao and Yizhou Zheng

    Article first published online : 12 MAR 2015, DOI: 10.1111/ejh.12471

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    Interleukin-21 Promotes Germinal Center Reaction by Skewing the Follicular Regulatory T Cell to Follicular Helper T Cell Balance in Autoimmune BXD2 Mice

    Arthritis & Rheumatology

    Volume 66, Issue 9, September 2014, Pages: 2601–2612, Yanna Ding, Jun Li, PingAr Yang, Bao Luo, Qi Wu, Allan J. Zajac, Oliver Wildner, Hui-Chen Hsu and John D. Mountz

    Article first published online : 26 AUG 2014, DOI: 10.1002/art.38735

  7. The role of IL-21 in regulating B-cell function in health and disease

    Immunological Reviews

    Volume 223, Issue 1, June 2008, Pages: 60–86, Rachel Ettinger, Stefan Kuchen and Peter E. Lipsky

    Article first published online : 8 JUL 2008, DOI: 10.1111/j.1600-065X.2008.00631.x

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    Interleukin-21 mediates hepatitis B virus-associated liver cirrhosis by activating hepatic stellate cells

    Hepatology Research

    Volume 44, Issue 10, October 2014, Pages: E198–E205, Guohua Feng, Ji-Yuan Zhang, Qing-Lei Zeng, Xi Yu, Zheng Zhang, Sa Lv, Xiangsheng Xu and Fu-Sheng Wang

    Article first published online : 27 AUG 2013, DOI: 10.1111/hepr.12215

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    Interleukin (IL)-21-independent pathogen-specific CD8+ T-cell expansion, and IL-21-dependent suppression of CD4+ T-cell IL-17 production


    Volume 131, Issue 2, October 2010, Pages: 183–191, James M. Ertelt, Tanner M. Johanns, Jared H. Rowe and Sing Sing Way

    Article first published online : 10 MAY 2010, DOI: 10.1111/j.1365-2567.2010.03287.x

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    IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo

    European Journal of Immunology

    Volume 38, Issue 7, July 2008, Pages: 1833–1838, Ivo Sonderegger, Jan Kisielow, Reto Meier, Cecile King and Manfred Kopf

    Article first published online : 10 JUN 2008, DOI: 10.1002/eji.200838511

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    Anti-tumour necrosis factor therapy enhances mucosal healing through down-regulation of interleukin-21 expression and T helper type 17 cell infiltration in Crohn's disease

    Clinical & Experimental Immunology

    Volume 173, Issue 1, July 2013, Pages: 102–111, C. Liu, X. Xia, W. Wu, R. Wu, M. Tang, T. Chen, F. Xu, Y. Cong, X. Xu and Z. Liu

    Article first published online : 6 JUN 2013, DOI: 10.1111/cei.12084

  12. Elevated serum levels of interleukin 21 are associated with disease severity in patients with psoriasis

    British Journal of Dermatology

    Volume 167, Issue 1, July 2012, Pages: 191–193, Z. He, L. Jin, Z.-F. Liu, L. Hu, E.-L. Dang, Z.-Z. Feng, Q.-J. Li and G. Wang

    Article first published online : 28 JUN 2012, DOI: 10.1111/j.1365-2133.2012.10899.x

  13. Increased levels of IL-21 responses are associated with the severity of liver injury in patients with chronic active hepatitis B

    Journal of Viral Hepatitis

    Volume 21, Issue 9, September 2014, Pages: e78–e88, Q. Pan, Y. Yu, Z. Tang, M. Xi, H. Jiang, Y. Xun, X. Liu, H. Liu, J. Hu and G. Zang

    Article first published online : 10 MAR 2014, DOI: 10.1111/jvh.12242

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    Oestrogen up-regulates interleukin-21 production by CD4+T lymphocytes in patients with systemic lupus erythematosus


    Volume 142, Issue 4, August 2014, Pages: 573–580, Jennifer Lee, Eun-Kyoung Shin, Seon-Yeong Lee, Yang-Mi Her, Mi-Kyung Park, Seung-Ki Kwok, Ji Hyeon Ju, Kyung-Su Park, Ho-Youn Kim, Mi-La Cho and Sung-Hwan Park

    Article first published online : 11 JUL 2014, DOI: 10.1111/imm.12263

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    Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21

    Arthritis & Rheumatism

    Volume 63, Issue 6, June 2011, Pages: 1689–1697, Travis Hughes, Xana Kim-Howard, Jennifer A. Kelly, Kenneth M. Kaufman, Carl D. Langefeld, Julie Ziegler, Elena Sanchez, Robert P. Kimberly, Jeffrey C. Edberg, Rosalind Ramsey-Goldman, Michelle Petri, John D. Reveille, Javier Martín, Elizabeth E. Brown, Luis M. Vilá, Graciela S. Alarcón, Judith A. James, Gary S. Gilkeson, Kathy L. Moser, Patrick M. Gaffney, Joan T. Merrill, Timothy J. Vyse, Marta E. Alarcón-Riquelme, BIOLUPUS Network, Swapan K. Nath, John B. Harley and Amr H. Sawalha

    Article first published online : 31 MAY 2011, DOI: 10.1002/art.30320

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    Interleukin-21 (IL-21) synergizes with IL-2 to enhance T-cell receptor-induced human T-cell proliferation and counteracts IL-2/transforming growth factor-β-induced regulatory T-cell development


    Volume 139, Issue 1, May 2013, Pages: 109–120, Alessandra Battaglia, Alexia Buzzonetti, Cinzia Baranello, Mara Fanelli, Marco Fossati, Valentina Catzola, Giovanni Scambia and Andrea Fattorossi

    Article first published online : 8 APR 2013, DOI: 10.1111/imm.12061

  17. Effect of serum interleukin 21 on the development of coronary artery disease


    Volume 122, Issue 9, September 2014, Pages: 842–847, Ru Ding, Wenwu Gao, Zhiqing He, Mingfang Liao, Feng Wu, Sili Zou, Lan Ma, Chun Liang and Zonggui Wu

    Article first published online : 28 MAR 2014, DOI: 10.1111/apm.12246

  18. Immune Modulation with Interleukin-21

    Annals of the New York Academy of Sciences

    Volume 1182, Issue 1, December 2009, Pages: 39–46, Neela S. Bhave and William E. Carson III

    Article first published online : 10 DEC 2009, DOI: 10.1111/j.1749-6632.2009.05071.x

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    Interleukin-21 promotes osteoclastogenesis in humans with rheumatoid arthritis and in mice with collagen-induced arthritis

    Arthritis & Rheumatism

    Volume 64, Issue 3, March 2012, Pages: 740–751, Seung-Ki Kwok, Mi-La Cho, Mi-Kyung Park, Hye-Joa Oh, Jin-Sil Park, Yang-Mi Her, Seon-Yeong Lee, Jeehee Youn, Ji Hyeon Ju, Kyung Su Park, Sung-Il Kim, Ho-Youn Kim and Sung-Hwan Park

    Article first published online : 28 FEB 2012, DOI: 10.1002/art.33390

  20. Biology of IL-21 and the IL-21 receptor

    Immunological Reviews

    Volume 202, Issue 1, December 2004, Pages: 84–95, Devangi S. Mehta, Andrea L. Wurster and Michael J. Grusby

    Article first published online : 11 NOV 2004, DOI: 10.1111/j.0105-2896.2004.00201.x