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There are 6501 results for: content related to: PIK3CA , a hotspot for postzygotic mutations in nonhereditary overgrowth syndromes

  1. Oncogenic PIK3CA mutations in lobular breast cancer progression

    Genes, Chromosomes and Cancer

    Volume 52, Issue 1, January 2013, Pages: 69–80, Matthias Christgen, Monika Noskowicz, Elisa Schipper, Henriette Christgen, Charlotte Heil, Till Krech, Florian Länger, Hans Kreipe and Ulrich Lehmann

    Version of Record online : 21 SEP 2012, DOI: 10.1002/gcc.22007

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    Oncogenic PIK3CA mutations in colorectal cancers and polyps

    International Journal of Cancer

    Volume 131, Issue 4, 15 August 2012, Pages: 813–820, Vicki L.J. Whitehall, Celestine Rickman, Catherine E. Bond, Ingunn Ramsnes, Sonia A. Greco, Aarti Umapathy, Diane McKeone, Rebecca J. Faleiro, Ron L. Buttenshaw, Daniel L. Worthley, Sam Nayler, Zhen Zhen Zhao, Grant W. Montgomery, Kylie-Ann Mallitt, Jeremy R. Jass, Nagahide Matsubara, Kenji Notohara, Tatsuhiro Ishii and Barbara A. Leggett

    Version of Record online : 19 NOV 2011, DOI: 10.1002/ijc.26440

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    PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer

    Cancer Medicine

    Volume 4, Issue 3, March 2015, Pages: 371–382, Gilles Manceau, Laetitia Marisa, Valérie Boige, Alex Duval, Marie-Pierre Gaub, Gérard Milano, Janick Selves, Sylviane Olschwang, Valérie Jooste, Michè le Legrain, Delphine Lecorre, Dominique Guenot, Marie-Christine Etienne-Grimaldi, Sylvain Kirzin, Laurent Martin, Come Lepage, Anne-Marie Bouvier and Pierre Laurent-Puig

    Version of Record online : 2 FEB 2015, DOI: 10.1002/cam4.370

  4. PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors

    Molecular Carcinogenesis

    Volume 54, Issue 7, July 2015, Pages: 566–576, Marta Dueñas, Mónica Martínez-Fernández, Ramón García-Escudero, Felipe Villacampa, Miriam Marqués, Cristina Saiz-Ladera, José Duarte, Victor Martínez, Mª José Gómez, Mª Luisa Martín, Manoli Fernández, Daniel Castellano, Francisco X. Real, Jose L. Rodriguez-Peralto, Federico De La Rosa and Jesús M. Paramio

    Version of Record online : 18 DEC 2013, DOI: 10.1002/mc.22125

  5. Tumor Heterogeneity Revealed by KRAS, BRAF, and PIK3CA Pyrosequencing: KRAS and PIK3CA Intratumor Mutation Profile Differences and Their Therapeutic Implications

    Human Mutation

    Volume 35, Issue 3, March 2014, Pages: 329–340, Vivian Kosmidou, Eftychia Oikonomou, Margarita Vlassi, Spyros Avlonitis, Anastasia Katseli, Iraklis Tsipras, Despina Mourtzoukou, Georgios Kontogeorgos, Georgios Zografos and Alexander Pintzas

    Version of Record online : 15 JAN 2014, DOI: 10.1002/humu.22496

  6. Mutual exclusiveness between PIK3CA and KRAS mutations in endometrial carcinoma

    International Journal of Gynecological Cancer

    Volume 18, Issue 6, November/December 2008, Pages: 1339–1343, S. KANG, S.S. SEO, H.J. CHANG, C.W. YOO, S.Y. PARK and S.M. DONG

    Version of Record online : 25 JAN 2008, DOI: 10.1111/j.1525-1438.2007.01172.x

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    Coexistent mutations of KRAS and PIK3CA affect the efficacy of NVP-BEZ235, a dual PI3K/MTOR inhibitor, in regulating the PI3K/MTOR pathway in colorectal cancer

    International Journal of Cancer

    Volume 133, Issue 4, 15 August 2013, Pages: 984–996, Areumnuri Kim, Jung-Eun Lee, Seung-Sook Lee, Cherin Kim, Sun-Joo Lee, Won-Suk Jang and Sunhoo Park

    Version of Record online : 8 MAR 2013, DOI: 10.1002/ijc.28073

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    p53 Loses grip on PIK3CA expression leading to enhanced cell survival during platinum resistance

    Molecular Oncology

    Volume 10, Issue 8, October 2016, Pages: 1283–1295, Bhushan Thakur, Pritha Ray

    Version of Record online : 29 JUN 2016, DOI: 10.1016/j.molonc.2016.06.006

  9. Frequent PIK3CA gene amplification and its clinical significance in colorectal cancer

    The Journal of Pathology

    Volume 219, Issue 3, November 2009, Pages: 337–346, Zeenath Jehan, Prashant Bavi, Mehar Sultana, Jehad Abubaker, Rong Bu, Azhar Hussain, Ghazi Alsbeih, Nasser Al-Sanea, Alaa Abduljabbar, Luai H Ashari, Samar Alhomoud, Fouad Al-Dayel, Shahab Uddin and Khawla S Al-Kuraya

    Version of Record online : 7 JUL 2009, DOI: 10.1002/path.2601

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    PIK3CA mutations in nasopharyngeal carcinoma

    International Journal of Cancer

    Volume 118, Issue 4, 15 February 2006, Pages: 1065–1067, Yvonne Yan-Yan Or, Angela Bik-Yu Hui, Ka-Fai To, Cleo Nga-Yee Lam and Kwok-Wai Lo

    Version of Record online : 19 AUG 2005, DOI: 10.1002/ijc.21444

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    Increased drug resistance is associated with reduced glucose levels and an enhanced glycolysis phenotype

    British Journal of Pharmacology

    Volume 171, Issue 13, July 2014, Pages: 3255–3267, B Bhattacharya, S H H Low, C Soh, N Kamal Mustapa, M Beloueche-Babari, K X Koh, J Loh and R Soong

    Version of Record online : 10 JUN 2014, DOI: 10.1111/bph.12668

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    Novel mutant-enriched sequencing identified high frequency of PIK3CA mutations in pharyngeal cancer

    International Journal of Cancer

    Volume 122, Issue 5, 1 March 2008, Pages: 1189–1194, Wanglong Qiu, Guo-Xia Tong, Spiros Manolidis, Lanny G. Close, Adel M. Assaad and Gloria H. Su

    Version of Record online : 7 NOV 2007, DOI: 10.1002/ijc.23217

  13. You have full text access to this OnlineOpen article
    Variation in organ-specific PIK3CA and KRAS mutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas

    Environmental and Molecular Mutagenesis

    Volume 58, Issue 7, August 2017, Pages: 466–476, Barbara L. Parsons, Karen L. McKim and Meagan B. Myers

    Version of Record online : 29 JUL 2017, DOI: 10.1002/em.22110

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    PIK3CA amplification is predictive of poor prognosis in Tunisian patients with nasopharyngeal carcinoma

    Cancer Science

    Volume 100, Issue 11, November 2009, Pages: 2034–2039, Ali Fendri, Abdelmajid Khabir, Wafa Mnejja, Tahia Sellami-Boudawara, Jamel Daoud, Mounir Frikha, Abdelmonem Ghorbel, Ali Gargouri and Raja Mokdad-Gargouri

    Version of Record online : 21 JUL 2009, DOI: 10.1111/j.1349-7006.2009.01292.x

  15. Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours and identify selective PIK3CA overexpression by gene amplification

    The Journal of Pathology

    Volume 214, Issue 3, February 2008, Pages: 347–356, B Angulo, A Suarez-Gauthier, F Lopez-Rios, PP Medina, E Conde, M Tang, G Soler, A Lopez-Encuentra, JC Cigudosa and M Sanchez-Cespedes

    Version of Record online : 8 NOV 2007, DOI: 10.1002/path.2267

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    Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma

    International Journal of Cancer

    Volume 104, Issue 3, 10 April 2003, Pages: 318–327, Do-Sun Byun, Kyucheol Cho, Byung-Kyu Ryu, Min-Goo Lee, Jae-Il Park, Kwon-Seok Chae, Hyo-Jong Kim and Sung-Gil Chi

    Version of Record online : 13 JAN 2003, DOI: 10.1002/ijc.10962

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    Defining the genomic landscape of head and neck cancers through next-generation sequencing

    Oral Diseases

    Volume 21, Issue 1, January 2015, Pages: e11–e24, G Rizzo, M Black, JS Mymryk, JW Barrett and AC Nichols

    Version of Record online : 30 APR 2014, DOI: 10.1111/odi.12246

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    Frequency of mesenchymal-epithelial transition factor gene (MET) and the catalytic subunit of phosphoinositide-3-kinase (PIK3CA) copy number elevation and correlation with outcome in patients with early stage breast cancer

    Cancer

    Volume 119, Issue 1, 1 January 2013, Pages: 7–15, Ana M. Gonzalez-Angulo, Huiqin Chen, Meghan S. Karuturi, Mariana Chavez-MacGregor, Spyrus Tsavachidis, Funda Meric-Bernstam, Kim-Anh Do, Gabriel N. Hortobagyi, Patricia A. Thompson, Gordon B. Mills, Melissa L. Bondy and George R. Blumenschein Jr

    Version of Record online : 26 JUN 2012, DOI: 10.1002/cncr.27608

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    PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma

    Cancer Science

    Volume 97, Issue 12, December 2006, Pages: 1351–1358, Ken-ichi Kozaki, Issei Imoto, Atiphan Pimkhaokham, Shogo Hasegawa, Hitoshi Tsuda, Ken Omura and Johji Inazawa

    Version of Record online : 17 OCT 2006, DOI: 10.1111/j.1349-7006.2006.00343.x

  20. Elucidating the prognostic significance of KRAS, NRAS, BRAF and PIK3CA mutations in Chinese patients with metastatic colorectal cancer

    Asia-Pacific Journal of Clinical Oncology

    Volume 11, Issue 2, June 2015, Pages: 160–169, Brigette B Ma, Frankie Mo, Joanna H Tong, Ashley Wong, SC Cesar Wong, Wing M Ho, Cherry Wu, Polly WY Lam, KF Chan, Timothy SK Chan, Wilson MS Tsui, Alex KH Tsang, Mandy NS Fung, Anthony TC Chan and Ka Fai To

    Version of Record online : 13 APR 2015, DOI: 10.1111/ajco.12342