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There are 17681 results for: content related to: γ-Secretase binding sites in aged and A lzheimer's disease human cerebrum: the choroid plexus as a putative origin of CSF A β

  1. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis

    European Journal of Neuroscience

    Volume 37, Issue 12, June 2013, Pages: 1962–1969, Yu Deng, Zhe Wang, Ruitao Wang, Xiaozhu Zhang, Shuting Zhang, Yili Wu, Matthias Staufenbiel, Fang Cai and Weihong Song

    Version of Record online : 16 JUN 2013, DOI: 10.1111/ejn.12235

  2. BACE2 degradation mediated by the macroautophagy–lysosome pathway

    European Journal of Neuroscience

    Volume 37, Issue 12, June 2013, Pages: 1970–1977, Xi Liu, Zhe Wang, Yili Wu, Jianping Wang and Weihong Song

    Version of Record online : 16 JUN 2013, DOI: 10.1111/ejn.12204

  3. You have free access to this content
    Intracellular Itinerary of Internalised β-Secretase, BACE1, and Its Potential Impact on β-Amyloid Peptide Biogenesis

    Traffic

    Volume 14, Issue 9, September 2013, Pages: 997–1013, Pei Zhi Cheryl Chia, Wei Hong Toh, Robyn Sharples, Isabelle Gasnereau, Andrew F. Hill and Paul A. Gleeson

    Version of Record online : 8 JUL 2013, DOI: 10.1111/tra.12088

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    Membrane Trafficking Pathways in Alzheimer's Disease

    Traffic

    Volume 13, Issue 6, June 2012, Pages: 759–770, Lawrence Rajendran and Wim Annaert

    Version of Record online : 17 FEB 2012, DOI: 10.1111/j.1600-0854.2012.01332.x

  5. You have full text access to this OnlineOpen article
    Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant

    Brain and Behavior

    Volume 2, Issue 3, May 2012, Pages: 270–282, Kazumi Motoki, Hideaki Kume, Akiko Oda, Akira Tamaoka, Ai Hosaka, Fuyuki Kametani and Wataru Araki

    Version of Record online : 29 APR 2012, DOI: 10.1002/brb3.52

  6. You have free access to this content
    β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 869–880, Jiangli Tan and Geneviève Evin

    Version of Record online : 23 JAN 2012, DOI: 10.1111/j.1471-4159.2011.07623.x

  7. ADAM10 and BACE1 are localized to synaptic vesicles

    Journal of Neurochemistry

    Volume 135, Issue 3, November 2015, Pages: 606–615, Jolanta L. Lundgren, Saheeb Ahmed, Sophia Schedin-Weiss, Gunnar K. Gouras, Bengt Winblad, Lars O. Tjernberg and Susanne Frykman

    Version of Record online : 17 SEP 2015, DOI: 10.1111/jnc.13287

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    Altered β-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain

    FEBS Letters

    Volume 580, Issue 28-29, December 11, 2006, Pages: 6550–6560, John H. Stockley, Rivka Ravid and Cora O’Neill

    Version of Record online : 13 NOV 2006, DOI: 10.1016/j.febslet.2006.10.076

  9. The diverse roles and multiple forms of focal adhesion kinase in brain

    European Journal of Neuroscience

    Volume 40, Issue 11, December 2014, Pages: 3573–3590, Beatriz G. Armendáriz, Maria del Mar Masdeu, Eduardo Soriano, Jesús M. Ureña and Ferran Burgaya

    Version of Record online : 27 SEP 2014, DOI: 10.1111/ejn.12737

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    Oxidative stress activates a positive feedback between the γ- and β-secretase cleavages of the β-amyloid precursor protein

    Journal of Neurochemistry

    Volume 104, Issue 3, February 2008, Pages: 683–695, Elena Tamagno, Michela Guglielmotto, Manuela Aragno, Roberta Borghi, Riccardo Autelli, Luca Giliberto, Giuseppe Muraca, Oliviero Danni, Xiongwei Zhu, Mark A. Smith, George Perry, Dong-Gyu Jo, Mark P. Mattson and Massimo Tabaton

    Version of Record online : 17 OCT 2007, DOI: 10.1111/j.1471-4159.2007.05072.x

  11. The Neuregulin1/ErbB system is selectively regulated during peripheral nerve degeneration and regeneration

    European Journal of Neuroscience

    Volume 43, Issue 3, February 2016, Pages: 351–364, Giulia Ronchi, Kirsten Haastert-Talini, Benedetta Elena Fornasari, Isabelle Perroteau, Stefano Geuna and Giovanna Gambarotta

    Version of Record online : 8 JUL 2015, DOI: 10.1111/ejn.12974

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    Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer’s disease

    Aging Cell

    Volume 11, Issue 4, August 2012, Pages: 559–568, A-Ryeong Gwon, Jong-Sung Park, Thiruma V. Arumugam, Yong-Kook Kwon, Sic L. Chan, Seol-Hee Kim, Sang-Ha Baik, Sunghee Yang, Young-Kwang Yun, Yuri Choi, Saerom Kim, Sung-Chun Tang, Dong-Hoon Hyun, Aiwu Cheng, Charles E. Dann III, Michel Bernier, Jaewon Lee, William R. Markesbery, Mark P. Mattson and Dong-Gyu Jo

    Version of Record online : 9 APR 2012, DOI: 10.1111/j.1474-9726.2012.00817.x

  13. The external globus pallidus: progress and perspectives

    European Journal of Neuroscience

    Volume 43, Issue 10, May 2016, Pages: 1239–1265, Daniel J. Hegeman, Ellie S. Hong, Vivian M. Hernández and C. Savio Chan

    Version of Record online : 28 MAR 2016, DOI: 10.1111/ejn.13196

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    Regulated intramembrane proteolysis – lessons from amyloid precursor protein processing

    Journal of Neurochemistry

    Volume 117, Issue 5, June 2011, Pages: 779–796, Stefan F. Lichtenthaler, Christian Haass and Harald Steiner

    Version of Record online : 14 APR 2011, DOI: 10.1111/j.1471-4159.2011.07248.x

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    β-Amyloid 1-42 induces physiological transcriptional regulation of BACE1

    Journal of Neurochemistry

    Volume 122, Issue 5, September 2012, Pages: 1023–1031, Alessandra Piccini, Roberta Borghi, Michela Guglielmotto, Elena Tamagno, Gabriella Cirmena, Anna Garuti, Valeria Pollero, Sergio Cammarata, Michele Fornaro, Massimo Messa, Laura Colombo, Mario Salmona, George Perry and Massimo Tabaton

    Version of Record online : 11 JUL 2012, DOI: 10.1111/j.1471-4159.2012.07834.x

  16. Cerebrovascular contributions to Alzheimer's disease pathophysiology and potential therapeutic interventions in mouse models

    European Journal of Neuroscience

    Volume 37, Issue 12, June 2013, Pages: 1994–2004, Lynsie A. M. Thomason, Bojana Stefanovic and JoAnne McLaurin

    Version of Record online : 16 JUN 2013, DOI: 10.1111/ejn.12181

  17. Presenilin 1 is involved in the maturation of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1)

    Journal of Neuroscience Research

    Volume 85, Issue 1, January 2007, Pages: 153–165, Akira Kuzuya, Kengo Uemura, Naoyuki Kitagawa, Nobuhisa Aoyagi, Takeshi Kihara, Haruaki Ninomiya, Shoichi Ishiura, Ryosuke Takahashi and Shun Shimohama

    Version of Record online : 30 OCT 2006, DOI: 10.1002/jnr.21104

  18. Clinical and neurobiological advances in promoting regeneration of the ventral root avulsion lesion

    European Journal of Neuroscience

    Volume 43, Issue 3, February 2016, Pages: 318–335, Ruben Eggers, Martijn R. Tannemaat, Fred De Winter, Martijn J. A. Malessy and Joost Verhaagen

    Version of Record online : 29 OCT 2015, DOI: 10.1111/ejn.13089

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    Transcriptional and post-transcriptional regulation of β-secretase

    IUBMB Life

    Volume 64, Issue 12, December 2012, Pages: 943–950, Elena Tamagno, M. Guglielmotto, D. Monteleone, A. Vercelli and M. Tabaton

    Version of Record online : 26 NOV 2012, DOI: 10.1002/iub.1099

  20. Neural oscillations during non-rapid eye movement sleep as biomarkers of circuit dysfunction in schizophrenia

    European Journal of Neuroscience

    Volume 39, Issue 7, April 2014, Pages: 1091–1106, Richard J. Gardner, Flavie Kersanté, Matthew W. Jones and Ullrich Bartsch

    Version of Record online : 8 APR 2014, DOI: 10.1111/ejn.12533