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There are 10022 results for: content related to: Hsp90, an unlikely ally in the war on cancer

  1. Hsp90 Inhibitors

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Brian S. J. Blagg and M. Kyle Hadden

    Published Online : 15 SEP 2010, DOI: 10.1002/0471266949.bmc212

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    Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol

    The FEBS Journal

    Volume 274, Issue 17, September 2007, Pages: 4453–4463, Stefan H. Millson, Andrew W. Truman, Attila Rácz, Bin Hu, Barry Panaretou, James Nuttall, Mehdi Mollapour, Csaba Söti and Peter W. Piper

    Version of Record online : 6 AUG 2007, DOI: 10.1111/j.1742-4658.2007.05974.x

  3. The Hsp90 Family of Molecular Chaperones

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    Protein Science Encyclopedia

    Klaus Richter, Birgit Meinlschmidt and Johannes Buchner

    Published Online : 15 MAR 2008, DOI: 10.1002/9783527610754.sf22

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    Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23

    The EMBO Journal

    Volume 19, Issue 21, November 1, 2000, Pages: 5930–5940, Jason C. Young and F. Ulrich Hartl

    Version of Record online : 1 NOV 2000, DOI: 10.1093/emboj/19.21.5930

  5. Computational Studies of Allosteric Regulation in the Hsp90 Molecular Chaperone: From Functional Dynamics and Protein Structure Networks to Allosteric Communications and Targeted Anti-Cancer Modulators

    Israel Journal of Chemistry

    Volume 54, Issue 8-9, August 2014, Pages: 1052–1064, Gennady M. Verkhivker

    Version of Record online : 19 FEB 2014, DOI: 10.1002/ijch.201300143

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    Heat shock protein 90 associates with Toll-like receptors 7/9 and mediates self-nucleic acid recognition in SLE

    European Journal of Immunology

    Volume 45, Issue 7, July 2015, Pages: 2028–2041, Keita Saito, Kazuharu Kukita, Goro Kutomi, Koichi Okuya, Hiroko Asanuma, Tetsuya Tabeya, Yasuka Naishiro, Motohisa Yamamoto, Hiroki Takahashi, Toshihiko Torigoe, Akira Nakai, Yasuhisa Shinomura, Koichi Hirata, Noriyuki Sato and Yasuaki Tamura

    Version of Record online : 28 APR 2015, DOI: 10.1002/eji.201445293

  7. Heat-Shock Protein 90 (Hsp90) as Anticancer Target for Drug Discovery: An Ample Computational Perspective

    Chemical Biology & Drug Design

    Volume 86, Issue 5, November 2015, Pages: 1131–1160, Hezekiel M. Kumalo, Soumendranath Bhakat and Mahmoud E. Soliman

    Version of Record online : 11 JUN 2015, DOI: 10.1111/cbdd.12582

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    Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

    The EMBO Journal

    Volume 19, Issue 16, August 15, 2000, Pages: 4310–4322, Pramod Pandey, Ayman Saleh, Atsuko Nakazawa, Shailendra Kumar, Srinivasa M. Srinivasula, Vijay Kumar, Ralph Weichselbaum, Carlo Nalin, Emad S. Alnemri, Donald Kufe and Surender Kharbanda

    Version of Record online : 15 AUG 2000, DOI: 10.1093/emboj/19.16.4310

  9. Control mechanisms of differential translation of Hsp90 isoforms in 9L rat gliosarcoma cells

    Journal of Cellular Biochemistry

    Volume 107, Issue 3, 1 June 2009, Pages: 418–427, Chih-Wei Lo, Yuo-Sheng Chang, Chih-Chung Chao, Margaret Dah-Tsyr Chang, Kun-Che Chang and Yiu-Kay Lai

    Version of Record online : 23 MAR 2009, DOI: 10.1002/jcb.22138

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    Brassinosteroid nuclear signaling recruits HSP90 activity

    New Phytologist

    Volume 203, Issue 3, August 2014, Pages: 743–757, Despina Samakovli, Theoni Margaritopoulou, Constantinos Prassinos, Dimitra Milioni and Polydefkis Hatzopoulos

    Version of Record online : 7 MAY 2014, DOI: 10.1111/nph.12843

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    PLCγ1–PKCγ Signaling-Mediated Hsp90α Plasma Membrane Translocation Facilitates Tumor Metastasis


    Volume 15, Issue 8, August 2014, Pages: 861–878, Jian Yang, Xiaomin Song, Yang Chen, Xin-an Lu, Yan Fu and Yongzhang Luo

    Version of Record online : 26 JUN 2014, DOI: 10.1111/tra.12179

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    Contribution of N- and C-terminal domains to the function of Hsp90 in Saccharomyces cerevisiae

    Molecular Microbiology

    Volume 34, Issue 4, November 1999, Pages: 701–713, Thomas Scheibel, Tina Weikl, Ronald Rimerman, David Smith, Susan Lindquist and Johannes Buchner

    Version of Record online : 1 MAR 2002, DOI: 10.1046/j.1365-2958.1999.01632.x

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    Molecular analysis of common wheat genes encoding three types of cytosolic heat shock protein 90 (Hsp90): functional involvement of cytosolic Hsp90s in the control of wheat seedling growth and disease resistance

    New Phytologist

    Volume 191, Issue 2, July 2011, Pages: 418–431, Guan-Feng Wang, Xuening Wei, Renchun Fan, Huanbin Zhou, Xianping Wang, Chunmei Yu, Lingli Dong, Zhenying Dong, Xiaojie Wang, Zhensheng Kang, Hongqing Ling, Qian-Hua Shen, Daowen Wang and Xiangqi Zhang

    Version of Record online : 13 APR 2011, DOI: 10.1111/j.1469-8137.2011.03715.x

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    Interaction of HSP90 to N-WASP leads to activation and protection from proteasome-dependent degradation

    The EMBO Journal

    Volume 24, Issue 8, April 20, 2005, Pages: 1557–1570, Sun Joo Park, Shiro Suetsugu and Tadaomi Takenawa

    Version of Record online : 24 MAR 2005, DOI: 10.1038/sj.emboj.7600586

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    The Hsp90–Sti1 interaction is critical for Leishmania donovani proliferation in both life cycle stages

    Cellular Microbiology

    Volume 15, Issue 4, April 2013, Pages: 585–600, Antje Hombach, Gabi Ommen, Mareike Chrobak and Joachim Clos

    Version of Record online : 20 NOV 2012, DOI: 10.1111/cmi.12057

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    HSP90s are required for NLR immune receptor accumulation in Arabidopsis

    The Plant Journal

    Volume 79, Issue 3, August 2014, Pages: 427–439, Shuai Huang, Jacqueline Monaghan, Xionghui Zhong, Ling Lin, Tongjun Sun, Oliver Xiaoou Dong and Xin Li

    Version of Record online : 30 JUN 2014, DOI: 10.1111/tpj.12573

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    Dynamics of the regulation of Hsp90 by the co-chaperone Sti1

    The EMBO Journal

    Volume 31, Issue 6, March 21, 2012, Pages: 1518–1528, Chung-Tien Lee, Christian Graf, Franz J Mayer, Sebastian M Richter and Matthias P Mayer

    Version of Record online : 21 FEB 2012, DOI: 10.1038/emboj.2012.37

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    Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

    Cellular Microbiology

    Volume 14, Issue 3, March 2012, Pages: 368–385, Paolo Montanari, Giuseppe Bozza, Barbara Capecchi, Elena Caproni, Riccardo Barrile, Nathalie Norais, Mirco Capitani, Michele Sallese, Paola Cecchini, Laura Ciucchi, Zhenai Gao, Rino Rappuoli, Mariagrazia Pizza, Beatrice Aricò and Marcello Merola

    Version of Record online : 8 DEC 2011, DOI: 10.1111/j.1462-5822.2011.01722.x

  19. Hsp90 Chaperones

    Standard Article


    Bettina K Zierer and Johannes Buchner

    Published Online : 17 DEC 2012, DOI: 10.1002/9780470015902.a0024154

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    Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones

    The EMBO Journal

    Volume 18, Issue 3, February 1, 1999, Pages: 754–762, Chrisostomos Prodromou, Giuliano Siligardi, Ronan O'Brien, Derek N. Woolfson, Lynne Regan, Barry Panaretou, John E. Ladbury, Peter W. Piper and Laurence H. Pearl

    Version of Record online : 1 FEB 1999, DOI: 10.1093/emboj/18.3.754