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There are 3030 results for: content related to: Interpreting the reasons for the choice and changing of two drug regimens in an observational cohort: comparison of a ritonavir-boosted protease inhibitor-based versus a nonnucleoside reverse transcriptase inhibitor-based first-line regimen

  1. Long-Term Effect of Rifampicin-Based Anti-TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8-Hydroxy-Efavirenz in Ethiopian Patients

    The Journal of Clinical Pharmacology

    Abiy Habtewold, Eleni Aklillu, Eyasu Makonnen, Wondwossen Amogne, Getnet Yimer, Getachew Aderaye, Leif Bertilsson, Joel S. Owen and Jürgen Burhenne

    Version of Record online : 29 MAY 2016, DOI: 10.1002/jcph.756

  2. Effect of Rifampicin and CYP2B6 Genotype on Long-Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis

    Clinical Pharmacology & Therapeutics

    Volume 90, Issue 3, September 2011, Pages: 406–413, E Ngaimisi, S Mugusi, O Minzi, P Sasi, K-D Riedel, A Suda, N Ueda, M Janabi, F Mugusi, W E Haefeli, L Bertilsson, J Burhenne and E Aklillu

    Version of Record online : 3 AUG 2011, DOI: 10.1038/clpt.2011.129

  3. Population pharmacogenetic-based pharmacokinetic modeling of efavirenz, 7-hydroxy- and 8-hydroxyefavirenz

    The Journal of Clinical Pharmacology

    Volume 54, Issue 1, January 2014, Pages: 87–96, A.M. Abdelhady, Z. Desta, F. Jiang, C.W. Yeo, J.G. Shin and B.R. Overholser

    Version of Record online : 19 NOV 2013, DOI: 10.1002/jcph.208

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    Enhanced oxidative stress and increased mitochondrial mass during Efavirenz-induced apoptosis in human hepatic cells

    British Journal of Pharmacology

    Volume 160, Issue 8, August 2010, Pages: 2069–2084, N Apostolova, LJ Gomez-Sucerquia, A Moran, A Alvarez, A Blas-Garcia and JV Esplugues

    Version of Record online : 7 MAY 2010, DOI: 10.1111/j.1476-5381.2010.00866.x

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    Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index

    British Journal of Clinical Pharmacology

    Volume 75, Issue 1, January 2013, Pages: 244–253, Fen Jiang, Zeruesenay Desta, Ji-Hong Shon, Chang-Woo Yeo, Ho-Sook Kim, Kwang-Hyeon Liu, Soo-Kyung Bae, Sang-Seop Lee, David A. Flockhart and Jae-Gook Shin

    Version of Record online : 14 DEC 2012, DOI: 10.1111/j.1365-2125.2012.04314.x

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    Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells


    Volume 52, Issue 1, July 2010, Pages: 115–125, Ana Blas-García, Nadezda Apostolova, Daniel Ballesteros, Daniel Monleón, Jose M. Morales, Milagros Rocha, Victor M. Victor and Juan V. Esplugues

    Version of Record online : 1 MAR 2010, DOI: 10.1002/hep.23647

  7. The Male Genital Tract Is Not a Pharmacological Sanctuary From Efavirenz

    Clinical Pharmacology & Therapeutics

    Volume 90, Issue 1, July 2011, Pages: 151–156, LB Avery, RP Bakshi, YJ Cao and CW Hendrix

    Version of Record online : 1 JUN 2011, DOI: 10.1038/clpt.2011.99

  8. Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele Carriers

    Journal of Cardiovascular Electrophysiology


    Version of Record online : 25 JUL 2016, DOI: 10.1111/jce.13032

  9. Non-nucleoside reverse transcriptase inhibitors: a review

    International Journal of Clinical Practice

    Volume 61, Issue 1, January 2007, Pages: 105–118, L. Waters, L. John and M. Nelson

    Version of Record online : 8 JAN 2007, DOI: 10.1111/j.1742-1241.2006.01146.x

  10. Efavirenz or nevirapine in three-drug combination therapy with two nucleoside-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals

    Intervention Review

    The Cochrane Library

    Lawrence CE Mbuagbaw, James H Irlam, Alicen Spaulding, George W Rutherford and Nandi Siegfried

    Published Online : 8 DEC 2010, DOI: 10.1002/14651858.CD004246.pub3

  11. You have full text access to this OnlineOpen article
    Paediatric European Network for Treatment of AIDS (PENTA) guidelines for treatment of paediatric HIV-1 infection 2015: optimizing health in preparation for adult life

    HIV Medicine

    A Bamford, A Turkova, H Lyall, C Foster, N Klein, D Bastiaans, D Burger, S Bernadi, K Butler, E Chiappini, P Clayden, M Della Negra, V Giacomet, C Giaquinto, D Gibb, L Galli, M Hainaut, M Koros, L Marques, E Nastouli, T Niehues, A Noguera-Julian, P Rojo, C Rudin, HJ Scherpbier, G Tudor-Williams, SB Welch and (PENTA Steering Committee)

    Version of Record online : 3 FEB 2015, DOI: 10.1111/hiv.12217

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    Efavirenz modulation of sleep spindles and sleep spectral profile

    Journal of Sleep Research

    Volume 24, Issue 1, February 2015, Pages: 66–73, Arthur A. Simen, Junshui Ma, Vladimir Svetnik, David Mayleben, James Maynard, Adam Roth, Lori Mixson, Robin Mogg, David Shera, Laura George, T. Chris Mast, Chan Beals, Aubrey Stoch, Arie Struyk, Norah Shire and Iain Fraser

    Version of Record online : 12 AUG 2014, DOI: 10.1111/jsr.12196

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    Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy


    Volume 54, Issue 3, 2 September 2011, Pages: 1009–1019, Nadezda Apostolova, Leysa J. Gomez-Sucerquia, Anna Gortat, Ana Blas-Garcia and Juan V. Esplugues

    Version of Record online : 2 AUG 2011, DOI: 10.1002/hep.24459

  14. Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro–In Vivo Extrapolation Model

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 4, October 2012, Pages: 494–502, M Siccardi, L Almond, A Schipani, C Csajka, C Marzolini, C Wyen, N H Brockmeyer, M Boffito, A Owen and D Back

    Version of Record online : 18 JUL 2012, DOI: 10.1038/clpt.2012.61

  15. Safety and efficacy of coformulated efavirenz/emtricitabine/tenofovir single-tablet regimen in treatment-naive patients infected with HIV-1

    Journal of Medical Virology

    Volume 87, Issue 2, February 2015, Pages: 187–191, Sébastien Gallien, Philippe Flandre, Nga Nguyen, Nathalie De Castro, Jean-Michel Molina and Constance Delaugerre

    Version of Record online : 28 JUL 2014, DOI: 10.1002/jmv.24023

  16. Cost-effectiveness analysis of tenofovir/emtricitabine and abacavir/lamivudine in combination with efavirenz or atazanavir/ritonavir for treatment-naïve adults with HIV-1 infection in the UK, based on the AIDS Clinical Trials Group 5202 clinical trial

    HIV Medicine

    Volume 17, Issue 7, August 2016, Pages: 505–515, E Wilkins, M Fisher, AJ Brogan, SE Talbird and EM La

    Version of Record online : 9 DEC 2015, DOI: 10.1111/hiv.12349

  17. Rapid identification of efavirenz metabolites in rats and humans by ultra high performance liquid chromatography combined with quadrupole time-of-flight tandem mass spectrometry

    Journal of Separation Science

    Volume 38, Issue 9, May 2015, Pages: 1529–1536, Yachen Deng, Rong Liu, Ping Yang and Jianying Liang

    Version of Record online : 26 MAR 2015, DOI: 10.1002/jssc.201401401

  18. Antiretroviral Solid Drug Nanoparticles with Enhanced Oral Bioavailability: Production, Characterization, and In Vitro–In Vivo Correlation

    Advanced Healthcare Materials

    Volume 3, Issue 3, March, 2014, Pages: 400–411, Tom O. McDonald, Marco Giardiello, Philip Martin, Marco Siccardi, Neill J. Liptrott, Darren Smith, Phill Roberts, Paul Curley, Alessandro Schipani, Saye H. Khoo, James Long, Alison J. Foster, Steven P. Rannard and Andrew Owen

    Version of Record online : 1 SEP 2013, DOI: 10.1002/adhm.201300280

  19. Multiple drugs and multiple targets: An analysis of the electrostatic determinants of binding between non-nucleoside HIV-1 reverse transcriptase inhibitors and variants of HIV-1 RT

    Proteins: Structure, Function, and Bioinformatics

    Volume 80, Issue 2, February 2012, Pages: 573–590, Mona S. Minkara, Pamela H. Davis and Mala L. Radhakrishnan

    Version of Record online : 17 NOV 2011, DOI: 10.1002/prot.23221

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    Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation

    FEBS Letters

    Volume 579, Issue 2, January 17, 2005, Pages: 379–384, Gilda Tachedjian, Katie L. Moore, Stephen P. Goff and Nicolas Sluis-Cremer

    Version of Record online : 14 DEC 2004, DOI: 10.1016/j.febslet.2004.11.099