Search Results

There are 7725 results for: content related to: Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models

  1. You have free access to this content
    YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells

    British Journal of Pharmacology

    Volume 172, Issue 1, January 2015, Pages: 214–234, S M Cheng, Y C Chang, C Y Liu, J Y C Lee, H H Chan, C W Kuo, K Y Lin, S L Tsai, S H Chen, C F Li, E Leung, J R Kanwar, C C Huang, J Y Chang and C H A Cheung

    Article first published online : 1 DEC 2014, DOI: 10.1111/bph.12935

  2. YM155 induces apoptosis through downregulation of specificity protein 1 and myeloid cell leukemia-1 in human oral cancer cell lines

    Journal of Oral Pathology & Medicine

    Khadka Sachita, Hyun-Ju Yu, Jun-Won Yun, Jeong-Sang Lee and Sung-Dae Cho

    Article first published online : 5 DEC 2014, DOI: 10.1111/jop.12299

  3. YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation

    International Journal of Cancer

    Volume 136, Issue 2, 15 January 2015, Pages: 299–309, Marzia Pennati, Stefania Sbarra, Michelandrea De Cesare, Alessia Lopergolo, Silvia L. Locatelli, Elisa Campi, Maria Grazia Daidone, Carmelo Carlo-Stella, Alessandro M. Gianni and Nadia Zaffaroni

    Article first published online : 5 JUN 2014, DOI: 10.1002/ijc.28993

  4. Pharmacokinetics, distribution and excretion of YM155 monobromide, a novel small-molecule survivin suppressant, in male and pregnant or lactating female rats

    Biopharmaceutics & Drug Disposition

    Volume 33, Issue 3, April 2012, Pages: 160–169, Tsuyoshi Minematsu, Takuya Sonoda, Tadashi Hashimoto, Megumi Iwai, Todd Oppeneer, Laurie Felder, Nobuaki Shirai, Aiji Miyashita and Takashi Usui

    Article first published online : 4 APR 2012, DOI: 10.1002/bdd.1781

  5. You have full text access to this OnlineOpen article
    A phase 2, multicenter, open-label study of sepantronium bromide (YM155) plus docetaxel in patients with stage III (unresectable) or stage IV melanoma

    Cancer Medicine

    Ragini Kudchadkar, Scott Ernst, Bartosz Chmielowski, Bruce G. Redman, Joyce Steinberg, Anne Keating, Fei Jie, Caroline Chen, Rene Gonzalez and Jeffrey Weber

    Article first published online : 23 DEC 2014, DOI: 10.1002/cam4.363

  6. You have free access to this content
    A phase II study of the survivin suppressant YM155 in patients with refractory diffuse large B-cell lymphoma

    Cancer

    Volume 118, Issue 12, 15 June 2012, Pages: 3128–3134, Bruce D. Cheson, Nancy L. Bartlett, Julie M. Vose, Andres Lopez-Hernandez, Amanda L. Seiz, Anne T. Keating and Setareh Shamsili

    Article first published online : 17 OCT 2011, DOI: 10.1002/cncr.26510

    Corrected by:

    Erratum: Erratum

    Vol. 118, Issue 17, 4365, Article first published online: 16 DEC 2011

  7. You have free access to this content
    Manipulating the apoptotic pathway: potential therapeutics for cancer patients

    British Journal of Clinical Pharmacology

    Volume 76, Issue 3, September 2013, Pages: 381–395, Darcy J. P. Bates and Lionel D. Lewis

    Article first published online : 20 AUG 2013, DOI: 10.1111/bcp.12193

  8. Examination of survivin expression in 50 chordoma specimens—A histological and in vitro study

    Journal of Orthopaedic Research

    Volume 33, Issue 5, May 2015, Pages: 771–778, Elke V. Froehlich, Beate Rinner, Alexander J. A. Deutsch, Katharina Meditz, Heike Knausz, Katharina Troppan, Susanne Scheipl, Christine Wibmer, Andreas Leithner, Bernadette Liegl and Birgit Lohberger

    Article first published online : 13 MAR 2015, DOI: 10.1002/jor.22819

  9. BIRC5 expression is a poor prognostic marker in Ewing sarcoma

    Pediatric Blood & Cancer

    Volume 60, Issue 1, January 2013, Pages: 35–40, Pooja Hingorani, Paul Dickman, Pamela Garcia-Filion, Andrea White-Collins, Edward A. Kolb and David O. Azorsa

    Article first published online : 7 SEP 2012, DOI: 10.1002/pbc.24290

  10. You have free access to this content
    Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases

    International Journal of Cancer

    Volume 133, Issue 10, 15 November 2013, Pages: 2341–2350, Michele Bernasconi, Seigo Ueda, Patricia Krukowski, Beat C. Bornhauser, Kristin Ladell, Marcus Dorner, Juerg A. Sigrist, Cristina Campidelli, Roberta Aslandogmus, Davide Alessi, Christoph Berger, Stefano A. Pileri, Roberto F. Speck and David Nadal

    Article first published online : 29 MAY 2013, DOI: 10.1002/ijc.28239

  11. Liquid chromatography–electrospray tandem mass spectrometric assay suitable for quantitation of YM155, a novel small-molecule survivin suppressant, in dog plasma

    Biomedical Chromatography

    Volume 22, Issue 7, July 2008, Pages: 763–769, Tsuyoshi Minematsu, Laurie Felder, Todd Oppeneer, Masashi Sakazume, Keishi Oikawa, Tadashi Hashimoto, Takashi Usui and Hidetaka Kamimura

    Article first published online : 18 MAR 2008, DOI: 10.1002/bmc.996

  12. You have full text access to this Open Access content
    In This Issue

    Cancer Science

    Volume 102, Issue 3, March 2011, Page: i,

    Article first published online : 18 JAN 2011, DOI: 10.1111/j.1349-7006.2011.01844.x

  13. You have free access to this content
    A Third-Generation Bisphosphonate, YM175, Inhibits Osteoclast Formation in Murine Cocultures by Inhibiting Proliferation of Precursor Cells via Supporting Cell-Dependent Mechanisms

    Journal of Bone and Mineral Research

    Volume 13, Issue 6, June 1998, Pages: 986–995, Miyuki Nishikawa, Michiko Yamamoto, Takehiko Murakami, Takuhiko Akatsu, Nobuo Kugai and Naokazu Nagata

    Article first published online : 1 JUN 1998, DOI: 10.1359/jbmr.1998.13.6.986

  14. You have full text access to this Open Access content
    Generation of 8-hydroxydeoxyguanosine from DNA using rat liver homogenates

    Cancer Science

    Volume 96, Issue 1, January 2005, Pages: 13–18, Minyi Shi, Haruko Takeshita, Masaharu Komatsu, Baohui Xu, Kohji Aoyama and Toru Takeuchi

    Article first published online : 13 JAN 2005, DOI: 10.1111/j.1349-7006.2005.00004.x

  15. Down-regulation of Akt by methanol extracts of Impatiens balsamina L. promotes apoptosis in human oral squamous cell carcinoma cell lines

    Journal of Oral Pathology & Medicine

    Ji-Ae Shin, Mi Heon Ryu, Ki-Han Kwon, BuYoung Choi and Sung-Dae Cho

    Article first published online : 12 SEP 2014, DOI: 10.1111/jop.12248

  16. You have free access to this content
    Prevention of venous thromboembolism with an oral factor Xa inhibitor, YM150, after total hip arthroplasty. A dose finding study (ONYX-2)

    Journal of Thrombosis and Haemostasis

    Volume 8, Issue 4, April 2010, Pages: 714–721, B. I. ERIKSSON, A. G. G. TURPIE, M. R. LASSEN, M. H. PRINS, G. AGNELLI, P. KÄLEBO, G. WETHERILL, J. W. WILPSHAAR, L. MEEMS and FOR THE ONYX-2 STUDY GROUP

    Article first published online : 17 JAN 2010, DOI: 10.1111/j.1538-7836.2010.03748.x

  17. You have full text access to this Open Access content
    Disrupted plasma membrane localization of equilibrative nucleoside transporter 2 in the chemoresistance of human pancreatic cells to gemcitabine (dFdCyd)

    Cancer Science

    Volume 102, Issue 3, March 2011, Pages: 622–629, Ren Nishio, Hiroyuki Tsuchiya, Toshihiro Yasui, Shizuka Matsuura, Keita Kanki, Akihiro Kurimasa, Ichiro Hisatome and Goshi Shiota

    Article first published online : 20 JAN 2011, DOI: 10.1111/j.1349-7006.2010.01837.x

  18. You have free access to this content
    Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer

    FEBS Journal

    Volume 281, Issue 1, January 2014, Pages: 115–128, Xue-Pu Sun, Xuesong Dong, Lele Lin, Xian Jiang, Zheng Wei, Bo Zhai, Bo Sun, Qiang Zhang, Xiaolong Wang, Hongchi Jiang, Geoffrey W. Krissansen, Haiquan Qiao and Xueying Sun

    Article first published online : 18 NOV 2013, DOI: 10.1111/febs.12577

  19. You have full text access to this Open Access content
    Increased expression of centrosomal α, γ-tubulin in atypical ductal hyperplasia and carcinoma of the breast

    Cancer Science

    Volume 100, Issue 4, April 2009, Pages: 580–587, Yun Niu, Tieju Liu, Gary M. K. Tse, Baocun Sun, Ruifang Niu, Hiu-ming Li, Hui Wang, Yi Yang, Xue Ye, Ying Wang, Qi Yu and Fei Zhang

    Article first published online : 2 FEB 2009, DOI: 10.1111/j.1349-7006.2008.01075.x

  20. You have full text access to this Open Access content
    Breast cancer resistance protein/ABCG2 is differentially regulated downstream of extracellular signal-regulated kinase

    Cancer Science

    Volume 100, Issue 6, June 2009, Pages: 1118–1127, Yasuo Imai, Kyoko Ohmori, Shin’ichi Yasuda, Mariko Wada, Tsukasa Suzuki, Kazunori Fukuda and Yoshihiko Ueda

    Article first published online : 12 MAR 2009, DOI: 10.1111/j.1349-7006.2009.01154.x