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There are 13800 results for: content related to: Broad spectrum and potent antitumor activities of YM155, a novel small-molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models

  1. You have free access to this content
    YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells

    British Journal of Pharmacology

    Volume 172, Issue 1, January 2015, Pages: 214–234, S M Cheng, Y C Chang, C Y Liu, J Y C Lee, H H Chan, C W Kuo, K Y Lin, S L Tsai, S H Chen, C F Li, E Leung, J R Kanwar, C C Huang, J Y Chang and C H A Cheung

    Version of Record online : 1 DEC 2014, DOI: 10.1111/bph.12935

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    YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation

    International Journal of Cancer

    Volume 136, Issue 2, 15 January 2015, Pages: 299–309, Marzia Pennati, Stefania Sbarra, Michelandrea De Cesare, Alessia Lopergolo, Silvia L. Locatelli, Elisa Campi, Maria Grazia Daidone, Carmelo Carlo-Stella, Alessandro M. Gianni and Nadia Zaffaroni

    Version of Record online : 5 JUN 2014, DOI: 10.1002/ijc.28993

  3. YM155 induces apoptosis through downregulation of specificity protein 1 and myeloid cell leukemia-1 in human oral cancer cell lines

    Journal of Oral Pathology & Medicine

    Volume 44, Issue 10, November 2015, Pages: 785–791, Khadka Sachita, Hyun-Ju Yu, Jun-Won Yun, Jeong-Sang Lee and Sung-Dae Cho

    Version of Record online : 5 DEC 2014, DOI: 10.1111/jop.12299

  4. Pharmacokinetics, distribution and excretion of YM155 monobromide, a novel small-molecule survivin suppressant, in male and pregnant or lactating female rats

    Biopharmaceutics & Drug Disposition

    Volume 33, Issue 3, April 2012, Pages: 160–169, Tsuyoshi Minematsu, Takuya Sonoda, Tadashi Hashimoto, Megumi Iwai, Todd Oppeneer, Laurie Felder, Nobuaki Shirai, Aiji Miyashita and Takashi Usui

    Version of Record online : 4 APR 2012, DOI: 10.1002/bdd.1781

  5. Dioxonaphthoimidazoliums are Potent and Selective Rogue Stem Cell Clearing Agents with SOX2-Suppressing Properties

    ChemMedChem

    Dr. Si-Han Sherman Ho, Dr. Azhar Ali, Yi-Cheng Ng, Dr. Kuen-Kuen Millie Lam, Prof. Shu Wang, Prof. Woon-Khiong Chan, Dr. Tan-Min Chin and Prof. Mei-Lin Go

    Version of Record online : 22 JUL 2016, DOI: 10.1002/cmdc.201600262

  6. You have full text access to this OnlineOpen article
    A phase 2, multicenter, open-label study of sepantronium bromide (YM155) plus docetaxel in patients with stage III (unresectable) or stage IV melanoma

    Cancer Medicine

    Volume 4, Issue 5, May 2015, Pages: 643–650, Ragini Kudchadkar, Scott Ernst, Bartosz Chmielowski, Bruce G. Redman, Joyce Steinberg, Anne Keating, Fei Jie, Caroline Chen, Rene Gonzalez and Jeffrey Weber

    Version of Record online : 23 DEC 2014, DOI: 10.1002/cam4.363

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    Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases

    International Journal of Cancer

    Volume 133, Issue 10, 15 November 2013, Pages: 2341–2350, Michele Bernasconi, Seigo Ueda, Patricia Krukowski, Beat C. Bornhauser, Kristin Ladell, Marcus Dorner, Juerg A. Sigrist, Cristina Campidelli, Roberta Aslandogmus, Davide Alessi, Christoph Berger, Stefano A. Pileri, Roberto F. Speck and David Nadal

    Version of Record online : 29 MAY 2013, DOI: 10.1002/ijc.28239

  8. Putative tumor suppression function of SIRT6 in endometrial cancer

    FEBS Letters

    Volume 589, Issue 17, August 04, 2015, Pages: 2274–2281, Tomohiko Fukuda, Osamu Wada-Hiraike, Katsutoshi Oda, Michihiro Tanikawa, Chinami Makii, Kanako Inaba, Aki Miyasaka, Yuichiro Miyamoto, Tetsu Yano, Daichi Maeda, Takeshi Sasaki, Kei Kawana, Masashi Fukayama, Yutaka Osuga and Tomoyuki Fujii

    Version of Record online : 13 JUL 2015, DOI: 10.1016/j.febslet.2015.06.043

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    A phase II study of the survivin suppressant YM155 in patients with refractory diffuse large B-cell lymphoma

    Cancer

    Volume 118, Issue 12, 15 June 2012, Pages: 3128–3134, Bruce D. Cheson, Nancy L. Bartlett, Julie M. Vose, Andres Lopez-Hernandez, Amanda L. Seiz, Anne T. Keating and Setareh Shamsili

    Version of Record online : 17 OCT 2011, DOI: 10.1002/cncr.26510

    Corrected by:

    Erratum: Erratum

    Vol. 118, Issue 17, 4365, Version of Record online: 16 DEC 2011

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    Examination of survivin expression in 50 chordoma specimens—A histological and in vitro study

    Journal of Orthopaedic Research

    Volume 33, Issue 5, May 2015, Pages: 771–778, Elke V. Froehlich, Beate Rinner, Alexander J. A. Deutsch, Katharina Meditz, Heike Knausz, Katharina Troppan, Susanne Scheipl, Christine Wibmer, Andreas Leithner, Bernadette Liegl and Birgit Lohberger

    Version of Record online : 13 MAR 2015, DOI: 10.1002/jor.22819

  11. You have full text access to this OnlineOpen article
    Drug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancer

    Cancer Science

    Volume 107, Issue 4, April 2016, Pages: 452–460, Yumiko Kiyohara, Kiyoshi Yoshino, Satoshi Kubota, Hiroaki Okuyama, Hiroko Endo, Yutaka Ueda, Toshihiro Kimura, Tadashi Kimura, Shoji Kamiura and Masahiro Inoue

    Version of Record online : 16 MAR 2016, DOI: 10.1111/cas.12898

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    Prevention of venous thromboembolism with an oral factor Xa inhibitor, YM150, after total hip arthroplasty. A dose finding study (ONYX-2)

    Journal of Thrombosis and Haemostasis

    Volume 8, Issue 4, April 2010, Pages: 714–721, B. I. ERIKSSON, A. G. G. TURPIE, M. R. LASSEN, M. H. PRINS, G. AGNELLI, P. KÄLEBO, G. WETHERILL, J. W. WILPSHAAR, L. MEEMS and FOR THE ONYX-2 STUDY GROUP

    Version of Record online : 17 JAN 2010, DOI: 10.1111/j.1538-7836.2010.03748.x

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    Up-regulation of survivin by AKT and hypoxia-inducible factor 1α contributes to cisplatin resistance in gastric cancer

    The FEBS Journal

    Volume 281, Issue 1, January 2014, Pages: 115–128, Xue-Pu Sun, Xuesong Dong, Lele Lin, Xian Jiang, Zheng Wei, Bo Zhai, Bo Sun, Qiang Zhang, Xiaolong Wang, Hongchi Jiang, Geoffrey W. Krissansen, Haiquan Qiao and Xueying Sun

    Version of Record online : 18 NOV 2013, DOI: 10.1111/febs.12577

  14. BIRC5 expression is a poor prognostic marker in Ewing sarcoma

    Pediatric Blood & Cancer

    Volume 60, Issue 1, January 2013, Pages: 35–40, Pooja Hingorani, Paul Dickman, Pamela Garcia-Filion, Andrea White-Collins, Edward A. Kolb and David O. Azorsa

    Version of Record online : 7 SEP 2012, DOI: 10.1002/pbc.24290

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    A dose escalation study of YM150, an oral direct factor Xa inhibitor, in the prevention of venous thromboembolism in elective primary hip replacement surgery

    Journal of Thrombosis and Haemostasis

    Volume 5, Issue 8, August 2007, Pages: 1660–1665, B. I. ERIKSSON, A. G. G. TURPIE, M. R. LASSEN, M. H. PRINS, G. AGNELLI, P. KÄLEBO, M. L. GAILLARD, L MEEMS and FOR THE ONYX STUDY GROUP

    Version of Record online : 1 JUN 2007, DOI: 10.1111/j.1538-7836.2007.02644.x

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    Manipulating the apoptotic pathway: potential therapeutics for cancer patients

    British Journal of Clinical Pharmacology

    Volume 76, Issue 3, September 2013, Pages: 381–395, Darcy J. P. Bates and Lionel D. Lewis

    Version of Record online : 20 AUG 2013, DOI: 10.1111/bcp.12193

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    A Third-Generation Bisphosphonate, YM175, Inhibits Osteoclast Formation in Murine Cocultures by Inhibiting Proliferation of Precursor Cells via Supporting Cell-Dependent Mechanisms

    Journal of Bone and Mineral Research

    Volume 13, Issue 6, June 1998, Pages: 986–995, Miyuki Nishikawa, Michiko Yamamoto, Takehiko Murakami, Takuhiko Akatsu, Nobuo Kugai and Naokazu Nagata

    Version of Record online : 1 JUN 1998, DOI: 10.1359/jbmr.1998.13.6.986

  18. Down-regulation of Akt by methanol extracts of Impatiens balsamina L. promotes apoptosis in human oral squamous cell carcinoma cell lines

    Journal of Oral Pathology & Medicine

    Volume 44, Issue 6, July 2015, Pages: 420–428, Ji-Ae Shin, Mi Heon Ryu, Ki-Han Kwon, BuYoung Choi and Sung-Dae Cho

    Version of Record online : 12 SEP 2014, DOI: 10.1111/jop.12248

  19. Turbulent boundary layers under irregular waves and currents: Experiments and the equivalent-wave concept

    Journal of Geophysical Research: Oceans

    Volume 121, Issue 4, April 2016, Pages: 2616–2640, Jing Yuan

    Version of Record online : 20 APR 2016, DOI: 10.1002/2015JC011551

  20. Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies

    Clinical & Experimental Allergy

    Volume 39, Issue 7, July 2009, Pages: 943–955, T. E. Sutherland, R. M. Maizels and J. E. Allen

    Version of Record online : 17 APR 2009, DOI: 10.1111/j.1365-2222.2009.03243.x