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There are 50897 results for: content related to: Ligand-triggered resistance to molecular targeted drugs in lung cancer: Roles of hepatocyte growth factor and epidermal growth factor receptor ligands

  1. You have full text access to this Open Access content
    Lower gefitinib dose led to earlier resistance acquisition before emergence of T790M mutation in epidermal growth factor receptor-mutated lung cancer model

    Cancer Science

    Volume 104, Issue 11, November 2013, Pages: 1440–1446, Hiromi Hayakawa, Eiki Ichihara, Kadoaki Ohashi, Takashi Ninomiya, Masayuki Yasugi, Saburo Takata, Katsuya Sakai, Kunio Matsumoto, Nagio Takigawa, Mitsune Tanimoto and Katsuyuki Kiura

    Article first published online : 25 OCT 2013, DOI: 10.1111/cas.12284

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    Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors

    Cancer Science

    Volume 103, Issue 11, November 2012, Pages: 1946–1954, Kunihiko Minakata, Fumiyuki Takahashi, Takeshi Nara, Muneaki Hashimoto, Ken Tajima, Akiko Murakami, Fariz Nurwidya, Suzu Yae, Fumiaki Koizumi, Hiroyuki Moriyama, Kuniaki Seyama, Kazuto Nishio and Kazuhisa Takahashi

    Article first published online : 14 SEP 2012, DOI: 10.1111/j.1349-7006.2012.02408.x

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    Significance of epithelial growth factor in the epithelial–mesenchymal transition of human gallbladder cancer cells

    Cancer Science

    Volume 103, Issue 6, June 2012, Pages: 1165–1171, Takamitsu Sasaki, Hiroki Kuniyasu, Yi Luo, Daisuke Kato, Satoshi Shinya, Kiyomu Fujii, Hitoshi Ohmori and Yuichi Yamashita

    Article first published online : 3 APR 2012, DOI: 10.1111/j.1349-7006.2012.02264.x

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    Echinoderm microtubule-associated protein-like 4–anaplastic lymphoma kinase-targeted therapy for advanced non-small cell lung cancer: Molecular and clinical aspects

    Cancer Science

    Volume 103, Issue 8, August 2012, Pages: 1391–1396, Isamu Okamoto and Kazuhiko Nakagawa

    Article first published online : 17 JUN 2012, DOI: 10.1111/j.1349-7006.2012.02327.x

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    Inverse correlation between Thr-669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation

    Cancer Science

    Volume 104, Issue 10, October 2013, Pages: 1315–1322, Kanae Sato, Myoung-Sook Shin, Ayaka Sakimura, Yue Zhou, Tomohiro Tanaka, Miho Kawanishi, Yuki Kawasaki, Satoru Yokoyama, Keiichi Koizumi, Ikuo Saiki and Hiroaki Sakurai

    Article first published online : 1 AUG 2013, DOI: 10.1111/cas.12225

  6. You have full text access to this OnlineOpen article
    Association between serum ligands and the skin toxicity of anti-epidermal growth factor receptor antibody in metastatic colorectal cancer

    Cancer Science

    Volume 106, Issue 5, May 2015, Pages: 604–610, Naoki Takahashi, Yasuhide Yamada, Koh Furuta, Kengo Nagashima, Akiko Kubo, Yusuke Sasaki, Hirokazu Shoji, Yoshitaka Honma, Satoru Iwasa, Natsuko Okita, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi and Yasuhiro Shimada

    Article first published online : 29 APR 2015, DOI: 10.1111/cas.12642

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    Acquisition of cancer stem cell-like properties in non-small cell lung cancer with acquired resistance to afatinib

    Cancer Science

    Volume 106, Issue 10, October 2015, Pages: 1377–1384, Shinsuke Hashida, Hiromasa Yamamoto, Kazuhiko Shien, Yuichiro Miyoshi, Tomoaki Ohtsuka, Ken Suzawa, Mototsugu Watanabe, Yuho Maki, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi and Shinichi Toyooka

    Article first published online : 30 SEP 2015, DOI: 10.1111/cas.12749

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    JAK2-related pathway induces acquired erlotinib resistance in lung cancer cells harboring an epidermal growth factor receptor-activating mutation

    Cancer Science

    Volume 103, Issue 10, October 2012, Pages: 1795–1802, Daijiro Harada, Nagio Takigawa, Nobuaki Ochi, Takashi Ninomiya, Masayuki Yasugi, Toshio Kubo, Hiromasa Takeda, Eiki Ichihara, Kadoaki Ohashi, Saburo Takata, Mitsune Tanimoto and Katsuyuki Kiura

    Article first published online : 23 JUL 2012, DOI: 10.1111/j.1349-7006.2012.02363.x

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    RAC1 inhibition as a therapeutic target for gefitinib-resistant non-small-cell lung cancer

    Cancer Science

    Volume 105, Issue 7, July 2014, Pages: 788–794, Naoki Kaneto, Satoru Yokoyama, Yoshihiro Hayakawa, Shinichiro Kato, Hiroaki Sakurai and Ikuo Saiki

    Article first published online : 15 MAY 2014, DOI: 10.1111/cas.12425

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    Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer

    Cancer Science

    Volume 104, Issue 10, October 2013, Pages: 1346–1352, Naomi Ono, Toshikazu Yamazaki, Toshiyuki Tsukaguchi, Toshihiko Fujii, Kiyoaki Sakata, Atsushi Suda, Takuo Tsukuda, Toshiyuki Mio, Nobuya Ishii, Osamu Kondoh and Yuko Aoki

    Article first published online : 20 AUG 2013, DOI: 10.1111/cas.12237

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    Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild-type colorectal cancer patients treated with cetuximab-based chemotherapy

    Cancer Science

    Volume 103, Issue 4, April 2012, Pages: 791–796, Yao-Yu Hsieh, Cheng-Hwai Tzeng, Ming-Huang Chen, Po-Min Chen and Wei-Shu Wang

    Article first published online : 22 FEB 2012, DOI: 10.1111/j.1349-7006.2012.02225.x

  12. Met interacts with EGFR and Ron in canine osteosarcoma

    Veterinary and Comparative Oncology

    Volume 11, Issue 2, June 2013, Pages: 124–139, J. K. McCleese, M. D. Bear, S. K. Kulp, C. Mazcko, C. Khanna and C. A. London

    Article first published online : 8 DEC 2011, DOI: 10.1111/j.1476-5829.2011.00309.x

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    Intracellular signals of lung cancer cells as possible therapeutic targets

    Cancer Science

    Volume 106, Issue 5, May 2015, Pages: 489–496, Kiyomichi Tanaka, Keiki Kumano and Hiroo Ueno

    Article first published online : 20 MAR 2015, DOI: 10.1111/cas.12643

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    Importance of the cytological samples for the epidermal growth factor receptor gene mutation test for non-small cell lung cancer

    Cancer Science

    Volume 104, Issue 3, March 2013, Pages: 291–297, Koichi Hagiwara and Kunihiko Kobayashi

    Article first published online : 24 JAN 2013, DOI: 10.1111/cas.12081

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    Enhanced gefitinib-induced repression of the epidermal growth factor receptor pathway by ataxia telangiectasia-mutated kinase inhibition in non-small-cell lung cancer cells

    Cancer Science

    Volume 107, Issue 4, April 2016, Pages: 444–451, Keizo Misumi, Jiying Sun, Aiko Kinomura, Yoshihiro Miyata, Morihito Okada and Satoshi Tashiro

    Article first published online : 16 MAR 2016, DOI: 10.1111/cas.12899

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    Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer

    Cancer Science

    Volume 104, Issue 12, December 2013, Pages: 1640–1646, Lu Zhao, Kazuo Yasumoto, Atsuhiro Kawashima, Takayuki Nakagawa, Shinji Takeuchi, Tadaaki Yamada, Kunio Matsumoto, Kazuhiko Yonekura, Osamu Yoshie and Seiji Yano

    Article first published online : 13 NOV 2013, DOI: 10.1111/cas.12301

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    Sensitivity and kinase activity of epidermal growth factor receptor (EGFR) exon 19 and others to EGFR-tyrosine kinase inhibitors

    Cancer Science

    Volume 104, Issue 5, May 2013, Pages: 584–589, Kazuto Furuyama, Taishi Harada, Eiji Iwama, Yoshimasa Shiraishi, Kyoko Okamura, Kayo Ijichi, Akiko Fujii, Keiichi Ota, Shuo Wang, Heyan Li, Koichi Takayama, Giuseppe Giaccone and Yoichi Nakanishi

    Article first published online : 28 MAR 2013, DOI: 10.1111/cas.12125

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    Liver–intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer

    Cancer Science

    Volume 103, Issue 9, September 2012, Pages: 1744–1750, Naoya Sakamoto, Naohide Oue, Kazuhiro Sentani, Katsuhiro Anami, Naohiro Uraoka, Yutaka Naito, Htoo Zarni Oo, Takao Hinoi, Hideki Ohdan, Kazuyoshi Yanagihara, Kazuhiko Aoyagi, Hiroki Sasaki and Wataru Yasui

    Article first published online : 16 JUL 2012, DOI: 10.1111/j.1349-7006.2012.02353.x

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    Oncogene swap as a novel mechanism of acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitor in lung cancer

    Cancer Science

    Volume 107, Issue 4, April 2016, Pages: 461–468, Hiroshi Mizuuchi, Kenichi Suda, Isao Murakami, Kazuko Sakai, Katsuaki Sato, Yoshihisa Kobayashi, Masaki Shimoji, Masato Chiba, Yuichi Sesumi, Kenji Tomizawa, Toshiki Takemoto, Yoshitaka Sekido, Kazuto Nishio and Tetsuya Mitsudomi

    Article first published online : 28 MAR 2016, DOI: 10.1111/cas.12905

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    Mechanisms of intrinsic and acquired resistance to kinase-targeted therapies

    Pigment Cell & Melanoma Research

    Volume 25, Issue 6, November 2012, Pages: 819–831, Shubha Bagrodia, Tod Smeal and Robert T. Abraham

    Article first published online : 14 SEP 2012, DOI: 10.1111/pcmr.12007