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There are 11592 results for: content related to: Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?

  1. You have full text access to this OnlineOpen article
    Targeting DNA damage response in cancer therapy

    Cancer Science

    Volume 105, Issue 4, April 2014, Pages: 370–388, Noriko Hosoya and Kiyoshi Miyagawa

    Version of Record online : 21 MAR 2014, DOI: 10.1111/cas.12366

  2. You have free access to this content
    Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo

    The EMBO Journal

    Volume 29, Issue 20, October 20, 2010, Pages: 3558–3570, Hiroyuki Niida, Kazuhiro Murata, Midori Shimada, Kumiko Ogawa, Kumiko Ohta, Kyoko Suzuki, Hidetsugu Fujigaki, Aik Kia Khaw, Birendranath Banerjee, M Prakash Hande, Tomomi Miyamoto, Ichiro Miyoshi, Tomoyuki Shirai, Noboru Motoyama, Mireille Delhase, Ettore Appella and Makoto Nakanishi

    Version of Record online : 10 SEP 2010, DOI: 10.1038/emboj.2010.218

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    Fission yeast chk1 mutants show distinct responses to different types of DNA damaging treatments

    Genes to Cells

    Volume 7, Issue 7, July 2002, Pages: 663–673, Stefania Francesconi, Monique Smeets, Muriel Grenon, Jeanne Tillit, Joël Blaisonneau and Giuseppe Baldacci

    Version of Record online : 25 JUN 2002, DOI: 10.1046/j.1365-2443.2002.00552.x

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    Non-thermal DNA damage of cancer cells using near-infrared irradiation

    Cancer Science

    Volume 103, Issue 8, August 2012, Pages: 1467–1473, Yohei Tanaka, Naoto Tatewaki, Hiroshi Nishida, Takahiro Eitsuka, Nobuo Ikekawa and Jun Nakayama

    Version of Record online : 17 MAY 2012, DOI: 10.1111/j.1349-7006.2012.02310.x

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    Roles of Chk1 in cell biology and cancer therapy

    International Journal of Cancer

    Volume 134, Issue 5, 1 March 2014, Pages: 1013–1023, Youwei Zhang and Tony Hunter

    Version of Record online : 28 MAY 2013, DOI: 10.1002/ijc.28226

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    14-3-3γ mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage

    The EMBO Journal

    Volume 29, Issue 16, August 18, 2010, Pages: 2802–2812, Kousuke Kasahara, Hidemasa Goto, Masato Enomoto, Yasuko Tomono, Tohru Kiyono and Masaki Inagaki

    Version of Record online : 16 JUL 2010, DOI: 10.1038/emboj.2010.157

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    Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects

    The EMBO Journal

    Volume 22, Issue 3, February 3, 2003, Pages: 713–723, George Zachos, Michael D. Rainey and David A.F. Gillespie

    Version of Record online : 3 FEB 2003, DOI: 10.1093/emboj/cdg060

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    Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism

    The EMBO Journal

    Volume 23, Issue 16, August 18, 2004, Pages: 3386–3396, Katsuhiro Uto, Daigo Inoue, Ken Shimuta, Nobushige Nakajo and Noriyuki Sagata

    Version of Record online : 22 JUL 2004, DOI: 10.1038/sj.emboj.7600328

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    Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition

    The EMBO Journal

    Volume 21, Issue 14, July 15, 2002, Pages: 3694–3703, Ken Shimuta, Nobushige Nakajo, Katsuhiro Uto, Yoshimasa Hayano, Kenji Okazaki and Noriyuki Sagata

    Version of Record online : 15 JUL 2002, DOI: 10.1093/emboj/cdf357

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    Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses

    The EMBO Journal

    Volume 17, Issue 24, December 15, 1998, Pages: 7239–7249, Rui G. Martinho, Howard D. Lindsay, Gail Flaggs, Anthony J. DeMaggio, Merl F. Hoekstra, Antony M. Carr and Nicola J. Bentley

    Version of Record online : 15 DEC 1998, DOI: 10.1093/emboj/17.24.7239

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    Novel indication for cancer therapy: Chk1 inhibition sensitizes tumor cells to antimitotics

    International Journal of Cancer

    Volume 115, Issue 4, 1 July 2005, Pages: 528–538, Zhan Xiao, John Xue, Dimitri Semizarov, Thomas J. Sowin, Saul H. Rosenberg and Haiying Zhang

    Version of Record online : 1 FEB 2005, DOI: 10.1002/ijc.20770

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    DNA damage control: regulation and functions of checkpoint kinase 1

    The FEBS Journal

    Volume 282, Issue 19, October 2015, Pages: 3681–3692, Veronique A. J. Smits and David A. Gillespie

    Version of Record online : 13 AUG 2015, DOI: 10.1111/febs.13387

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    Regulation of checkpoint kinases through dynamic interaction with Crb2

    The EMBO Journal

    Volume 23, Issue 2, January 28, 2004, Pages: 418–428, Satoru Mochida, Fumiko Esashi, Nobuki Aono, Katsuyuki Tamai, Matthew J O'Connell and Mitsuhiro Yanagida

    Version of Record online : 22 JAN 2004, DOI: 10.1038/sj.emboj.7600018

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    Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1)

    Genes to Cells

    Volume 11, Issue 5, May 2006, Pages: 477–485, Takashi Shiromizu, Hidemasa Goto, Yasuko Tomono, Jiri Bartek, Go Totsukawa, Akihito Inoko, Makoto Nakanishi, Fumio Matsumura and Masaki Inagaki

    Version of Record online : 21 MAR 2006, DOI: 10.1111/j.1365-2443.2006.00955.x

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    Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling

    The EMBO Journal

    Volume 31, Issue 10, May 16, 2012, Pages: 2365–2377, Ning Liu, Masaki Matsumoto, Kyoko Kitagawa, Yojiro Kotake, Sayuri Suzuki, Senji Shirasawa, Keiichi I Nakayama, Makoto Nakanishi, Hiroyuki Niida and Masatoshi Kitagawa

    Version of Record online : 13 APR 2012, DOI: 10.1038/emboj.2012.88

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    U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint

    Journal of Cellular and Molecular Medicine

    Volume 13, Issue 8a, August 2009, Pages: 1565–1576, Laura Carrassa, Yolanda Sanchez, Eugenio Erba and Giovanna Damia

    Version of Record online : 23 SEP 2009, DOI: 10.1111/j.1582-4934.2008.00362.x

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    Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation

    The EMBO Journal

    Volume 16, Issue 3, February 1, 1997, Pages: 545–554, Matthew J. O'Connell, Jeanette M. Raleigh, Heather M. Verkade and Paul Nurse

    Version of Record online : 1 FEB 1997, DOI: 10.1093/emboj/16.3.545

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    Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1

    The EMBO Journal

    Volume 23, Issue 4, February 25, 2004, Pages: 908–918, Nicole R den Elzen and Matthew J O'Connell

    Version of Record online : 5 FEB 2004, DOI: 10.1038/sj.emboj.7600105

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    Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G2 checkpoint arrest

    Journal of Cellular and Molecular Medicine

    Volume 15, Issue 7, July 2011, Pages: 1528–1541, Angela Poehlmann, Caroline Habold, Diana Walluscheck, Kathrin Reissig, Khuloud Bajbouj, Oliver Ullrich, Roland Hartig, Hala Gali-Muhtasib, Antje Diestel, Albert Roessner and Regine Schneider-Stock

    Version of Record online : 22 JUN 2011, DOI: 10.1111/j.1582-4934.2010.01143.x

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    The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1

    Genes to Cells

    Volume 11, Issue 9, September 2006, Pages: 993–1007, Yoshitami Hashimoto, Tsuyoshi Tsujimura, Akio Sugino and Haruhiko Takisawa

    Version of Record online : 19 JUL 2006, DOI: 10.1111/j.1365-2443.2006.00998.x