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There are 7352 results for: content related to: Echinoderm microtubule-associated protein-like 4–anaplastic lymphoma kinase-targeted therapy for advanced non-small cell lung cancer: Molecular and clinical aspects

  1. You have free access to this content
    ALK-positive non–small cell lung cancer: Mechanisms of resistance and emerging treatment options


    Volume 120, Issue 16, August 15, 2014, Pages: 2392–2402, Conor E. Steuer and Suresh S. Ramalingam

    Version of Record online : 22 MAY 2014, DOI: 10.1002/cncr.28597

  2. You have full text access to this OnlineOpen article
    Crizotinib-Resistant Mutants of EML4-ALK Identified Through an Accelerated Mutagenesis Screen

    Chemical Biology & Drug Design

    Volume 78, Issue 6, December 2011, Pages: 999–1005, Sen Zhang, Frank Wang, Jeffrey Keats, Xiaotian Zhu, Yaoyu Ning, Scott D. Wardwell, Lauren Moran, Qurish K. Mohemmad, Rana Anjum, Yihan Wang, Narayana I. Narasimhan, David Dalgarno, William C. Shakespeare, Juan J. Miret, Tim Clackson and Victor M. Rivera

    Version of Record online : 31 OCT 2011, DOI: 10.1111/j.1747-0285.2011.01239.x

  3. You have full text access to this OnlineOpen article
    Activity of second-generation ALK inhibitors against crizotinib-resistant mutants in an NPM-ALK model compared to EML4-ALK

    Cancer Medicine

    Volume 4, Issue 7, July 2015, Pages: 953–965, Diletta Fontana, Monica Ceccon, Carlo Gambacorti-Passerini and Luca Mologni

    Version of Record online : 26 FEB 2015, DOI: 10.1002/cam4.413

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    Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein

    British Journal of Pharmacology

    Volume 166, Issue 5, July 2012, Pages: 1669–1683, Wen-jing Zhou, Xu Zhang, Chao Cheng, Fang Wang, Xiao-kun Wang, Yong-ju Liang, Kenneth Kin Wah To, Wang Zhou, Hong-bing Huang and Li-wu Fu

    Version of Record online : 21 JUN 2012, DOI: 10.1111/j.1476-5381.2012.01849.x

  5. Current Status of Targeted Therapy for Anaplastic Lymphoma Kinase–Rearranged Non–Small Cell Lung Cancer

    Clinical Pharmacology & Therapeutics

    Volume 95, Issue 1, January 2014, Pages: 15–23, B Solomon, KD Wilner and AT Shaw

    Version of Record online : 19 DEC 2013, DOI: 10.1038/clpt.2013.200

  6. Targeting ALK Rearrangements

    Lung Cancer, Fourth Edition

    Justin F. Gainor, Alice T. Shaw, Pages: 541–556, 2014

    Published Online : 4 APR 2014, DOI: 10.1002/9781118468791.ch35

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    In vivo imaging models of bone and brain metastases and pleural carcinomatosis with a novel human EML4-ALK lung cancer cell line

    Cancer Science

    Volume 106, Issue 3, March 2015, Pages: 244–252, Shigeki Nanjo, Takayuki Nakagawa, Shinji Takeuchi, Kenji Kita, Koji Fukuda, Mitsutoshi Nakada, Hisanori Uehara, Hiroshi Nishihara, Eiji Hara, Hidetaka Uramoto, Fumihiro Tanaka and Seiji Yano

    Version of Record online : 17 FEB 2015, DOI: 10.1111/cas.12600

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    Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar

    International Journal of Cancer

    Volume 134, Issue 6, 15 March 2014, Pages: 1484–1494, Seng Chuan Tang, Luan N. Nguyen, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel

    Version of Record online : 3 OCT 2013, DOI: 10.1002/ijc.28475

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    Rapid-onset hypogonadism secondary to crizotinib use in men with metastatic nonsmall cell lung cancer


    Volume 118, Issue 21, 1 November 2012, Pages: 5302–5309, Andrew J. Weickhardt, Micol S. Rothman, Smita Salian-Mehta, Katja Kiseljak-Vassiliades, Ana B. Oton, Robert C. Doebele, Margaret E. Wierman and D. Ross Camidge

    Version of Record online : 4 APR 2012, DOI: 10.1002/cncr.27450

  10. You have full text access to this OnlineOpen article
    Crizotinib versus platinum-based double-agent chemotherapy as the first line treatment in advanced anaplastic lymphoma kinase-positive lung adenocarcinoma

    Thoracic Cancer

    Volume 7, Issue 1, January 2016, Pages: 3–8, Quan Zhang, Na Qin, Jinghui Wang, Jialin Lv, Xinjie Yang, Xi Li, Jingying Nong, Hui Zhang, Xinyong Zhang, Yuhua Wu and Shucai Zhang

    Version of Record online : 23 APR 2015, DOI: 10.1111/1759-7714.12264

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    Diagnostic assays for identification of anaplastic lymphoma kinase-positive non–small cell lung cancer


    Volume 119, Issue 8, 15 April 2013, Pages: 1467–1477, Andrew J. Weickhardt, Dara L. Aisner, Wilbur A. Franklin, Marileila Varella-Garcia, Robert C. Doebele and D. Ross Camidge

    Version of Record online : 20 DEC 2012, DOI: 10.1002/cncr.27913

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    Favorable response to crizotinib in three patients with echinoderm microtubule-associated protein-like 4–anaplastic lymphoma kinase fusion-type oncogene-positive non-small cell lung cancer

    Cancer Science

    Volume 102, Issue 8, August 2011, Pages: 1602–1604, Takashi Kijima, Kengo Takeuchi, Satoshi Tetsumoto, Kazuki Shimada, Ryo Takahashi, Haruhiko Hirata, Izumi Nagatomo, Shigenori Hoshino, Yoshito Takeda, Hiroshi Kida, Sho Goya, Isao Tachibana and Ichiro Kawase

    Version of Record online : 18 JUL 2011, DOI: 10.1111/j.1349-7006.2011.01970.x

  13. Computational Investigation and Experimental Validation of Crizotinib Resistance Conferred by C1156Y Mutant Anaplastic Lymphoma Kinase

    Molecular Informatics

    Volume 34, Issue 2-3, February 2015, Pages: 105–114, Anish Kumar, V. Shanthi and K. Ramanathan

    Version of Record online : 30 JAN 2015, DOI: 10.1002/minf.201400070

  14. Equivocal ALK fluorescence in-situ hybridization (FISH) cases may benefit from ancillary ALKFISH probe testing


    Volume 67, Issue 5, November 2015, Pages: 654–663, Christina Selinger, Wendy Cooper, Trina Lum, Catriona McNeil, Adrienne Morey, Paul Waring, Benhur Amanuel, Michael Millward, Joanne Peverall, Chris Van Vliet, Michael Christie, Yen Tran, Connie Diakos, Nick Pavlakis, Anthony J Gill and Sandra O'Toole

    Version of Record online : 24 MAY 2015, DOI: 10.1111/his.12708

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    Ligand-triggered resistance to molecular targeted drugs in lung cancer: Roles of hepatocyte growth factor and epidermal growth factor receptor ligands

    Cancer Science

    Volume 103, Issue 7, July 2012, Pages: 1189–1194, Seiji Yano, Shinji Takeuchi, Takayuki Nakagawa and Tadaaki Yamada

    Version of Record online : 9 MAY 2012, DOI: 10.1111/j.1349-7006.2012.02279.x

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    Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients


    Volume 119, Issue 13, 01 July 2013, Pages: 2383–2390, Andrew J. Weickhardt, Robert C. Doebele, W. Thomas Purcell, Paul A. Bunn, Ana B. Oton, Micol S. Rothman, Margaret E. Wierman, Tony Mok, Sanjay Popat, Julie Bauman, Jorge Nieva, Silvia Novello, Sai-Hong Ignatius Ou and D. Ross Camidge

    Version of Record online : 12 APR 2013, DOI: 10.1002/cncr.28089

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    Correlations between the percentage of tumor cells showing an anaplastic lymphoma kinase (ALK) gene rearrangement, ALK signal copy number, and response to crizotinib therapy in ALK fluorescence in situ hybridization–positive nonsmall cell lung cancer


    Volume 118, Issue 18, 15 September 2012, Pages: 4486–4494, D. Ross Camidge, Mariana Theodoro, DeLee A. Maxson, Margaret Skokan, Tara O'Brien, Xian Lu, Robert C. Doebele, Anna E. Barón and Marileila Varella-Garcia

    Version of Record online : 26 JAN 2012, DOI: 10.1002/cncr.27411

  18. You have full text access to this OnlineOpen article
    Complex renal cysts associated with crizotinib treatment

    Cancer Medicine

    Volume 4, Issue 6, June 2015, Pages: 887–896, Patrick Schnell, Cynthia H. Bartlett, Benjamin J. Solomon, Vanessa Tassell, Alice T. Shaw, Tommaso de Pas, Soo-Hyun Lee, Geon Kook Lee, Kaoru Tanaka, Weiwei Tan, Yiyun Tang, Keith D. Wilner, Allan Safferman and Ji-Youn Han

    Version of Record online : 10 MAR 2015, DOI: 10.1002/cam4.437

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    Is there a progression-free survival benefit of first-line crizotinib versus standard chemotherapy and second-line crizotinib in ALK-positive advanced lung adenocarcinoma? A retrospective study of Chinese patients

    Cancer Medicine

    Volume 5, Issue 6, June 2016, Pages: 1013–1021, Shaohua Cui, Yizhuo Zhao, Lili Dong, Aiqin Gu, Liwen Xiong, Jialin Qian, Wei Zhang, Yanjie Niu, Feng Pan and Liyan Jiang

    Version of Record online : 16 FEB 2016, DOI: 10.1002/cam4.659

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    Hypogonadism related to crizotinib therapy


    Volume 118, Issue 21, 1 November 2012, Pages: E1–E2, Suresh S. Ramalingam and Alice T. Shaw

    Version of Record online : 4 APR 2012, DOI: 10.1002/cncr.27561