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There are 9640 results for: content related to: Phase I / II study of decitabine in patients with myelodysplastic syndrome: A multi-center study in J apan

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    Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo

    International Journal of Cancer

    Volume 131, Issue 1, 1 July 2012, Pages: 18–29, Oscar Alcazar, Susan Achberger, Wayne Aldrich, Zhenbo Hu, Soledad Negrotto, Yogen Saunthararajah and Pierre Triozzi

    Version of Record online : 6 SEP 2011, DOI: 10.1002/ijc.26320

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    Safety and clinical activity of 5-aza-2′-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia

    British Journal of Haematology

    Volume 167, Issue 3, November 2014, Pages: 356–365, Christopher B. Benton, Deborah A. Thomas, Hui Yang, Farhad Ravandi, Michael Rytting, Susan O'Brien, Anna R. Franklin, Gautam Borthakur, Samuel Dara, Monica Kwari, Sherry R. Pierce, Elias Jabbour, Hagop Kantarjian and Guillermo Garcia-Manero

    Version of Record online : 26 JUL 2014, DOI: 10.1111/bjh.13050

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    Evolution of decitabine development


    Volume 112, Issue 11, 1 June 2008, Pages: 2341–2351, Elias Jabbour, Jean-Pierre Issa, Guillermo Garcia-Manero and Hagop Kantarjian

    Version of Record online : 8 APR 2008, DOI: 10.1002/cncr.23463

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    Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation

    British Journal of Haematology

    Volume 150, Issue 2, July 2010, Pages: 189–195, Kristie A. Blum, Zhongfa Liu, David M. Lucas, Ping Chen, Zhiliang Xie, Robert Baiocchi, Donald M. Benson, Steven M. Devine, Jeffrey Jones, Leslie Andritsos, Joseph Flynn, Christoph Plass, Guido Marcucci, Kenneth K. Chan, Michael R. Grever and John C. Byrd

    Version of Record online : 29 APR 2010, DOI: 10.1111/j.1365-2141.2010.08213.x

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    Inhibition of bladder cancer invasion by Sp1-mediated BTG2 expression via inhibition of DNA methyltransferase 1

    The FEBS Journal

    Volume 281, Issue 24, December 2014, Pages: 5581–5601, Preethi Devanand, Sun Il Kim, Yong Won Choi, Seung Soo Sheen, Hyunee Yim, Min Sook Ryu, Se Joong Kim, Wun-Jae Kim and In Kyoung Lim

    Version of Record online : 30 OCT 2014, DOI: 10.1111/febs.13099

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    Decitabine improves patient outcomes in myelodysplastic syndromes


    Volume 106, Issue 8, 15 April 2006, Pages: 1794–1803, Hagop Kantarjian, Jean-Pierre J. Issa, Craig S. Rosenfeld, John M. Bennett, Maher Albitar, John DiPersio, Virginia Klimek, James Slack, Carlos de Castro, Farhad Ravandi, Richard Helmer III, Lanlan Shen, Stephen D. Nimer, Richard Leavitt, Azra Raza and Hussain Saba

    Version of Record online : 13 MAR 2006, DOI: 10.1002/cncr.21792

  7. Treatment with the cancer drugs decitabine and doxorubicin induces human skin keratinocytes to express Oct4 and the OCT4 regulator mir-145

    The Journal of Dermatology

    Volume 39, Issue 7, July 2012, Pages: 617–624, Sathivel CHINNATHAMBI, Susan WIECHERT, Ann TOMANEK-CHALKLEY, Michael C. WINTER and Jackie R. BICKENBACH

    Version of Record online : 9 APR 2012, DOI: 10.1111/j.1346-8138.2012.01553.x

  8. Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2′-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method

    Rapid Communications in Mass Spectrometry

    Volume 20, Issue 7, 15 April 2006, Pages: 1117–1126, Zhongfa Liu, Guido Marcucci, John C. Byrd, Michael Grever, Jim Xiao and Kenneth K. Chan

    Version of Record online : 7 MAR 2006, DOI: 10.1002/rcm.2423

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    Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome


    Volume 109, Issue 2, 15 January 2007, Pages: 265–273, Hagop M. Kantarjian, Susan O'Brien, Jianqin Shan, Ahmed Aribi, Guillermo Garcia-Manero, Elias Jabbour, Farhad Ravandi, Jorge Cortes, Jan Davisson and Jean-Pierre Issa

    Version of Record online : 28 NOV 2006, DOI: 10.1002/cncr.22376

  10. Epigenetische Therapie bei Myelodysplastischen Syndromen (MDS). Therapie mit DNA-Methyltransferase-Inhibitoren

    Pharmazie in unserer Zeit

    Volume 39, Issue 3, Mai 2010, Pages: 217–227, Michael Daskalakis, Nadja Blagitko-Dorfs, Björn Hackanson and Michael Lübbert

    Version of Record online : 27 APR 2010, DOI: 10.1002/pauz.201000369

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    Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome


    Volume 109, Issue 6, 15 March 2007, Pages: 1133–1137, Hagop M. Kantarjian, Susan O'Brien, Xuelin Huang, Guillermo Garcia-Manero, Farhad Ravandi, Jorge Cortes, Jianqin Shan, Jan Davisson, Carlos E. Bueso-Ramos and Jean-Pierre Issa

    Version of Record online : 21 FEB 2007, DOI: 10.1002/cncr.22508

  12. Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: A children's oncology group study

    Pediatric Blood & Cancer

    Volume 55, Issue 4, October 2010, Pages: 629–638, Rani E. George, Jill M. Lahti, Peter C. Adamson, Kejin Zhu, David Finkelstein, A. Mark Ingle, Joel M. Reid, Mark Krailo, Donna Neuberg, Susan M. Blaney and Lisa Diller

    Version of Record online : 29 JUN 2010, DOI: 10.1002/pbc.22607

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    A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer


    Volume 116, Issue 17, 1 September 2010, Pages: 4043–4053, Fang Fang, Curt Balch, Jeanne Schilder, Timothy Breen, Shu Zhang, Changyu Shen, Lang Li, Carol Kulesavage, Anthony J. Snyder, Kenneth P. Nephew and Daniela E. Matei

    Version of Record online : 19 AUG 2010, DOI: 10.1002/cncr.25204

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    Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition

    British Journal of Haematology

    Volume 138, Issue 5, September 2007, Pages: 616–623, Si Ho Choi, Hyang-Min Byun, Jennifer M. Kwan, Jean-Pierre J. Issa and Allen S. Yang

    Version of Record online : 2 AUG 2007, DOI: 10.1111/j.1365-2141.2007.06707.x

  15. The European Medicines Agency Review of Decitabine (Dacogen) for the Treatment of Adult Patients With Acute Myeloid Leukemia: Summary of the Scientific Assessment of the Committee for Medicinal Products for Human Use

    The Oncologist

    Volume 21, Issue 6, June 2016, Pages: 692–700, Maria Nieto, Pierre Demolis, Eliane Béhanzin, Alexandre Moreau, Ian Hudson, Beatriz Flores, Henry Stemplewski, Tomas Salmonson, Christian Gisselbrecht, David Bowen and Francesco Pignatti

    Version of Record online : 18 APR 2016, DOI: 10.1634/theoncologist.2015-0298

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    Oral decitabine reactivates expression of the methylated γ-globin gene in Papio anubis

    American Journal of Hematology

    Volume 82, Issue 11, November 2007, Pages: 981–985, Donald Lavelle, Janet Chin, Kestis Vaitkus, Sanjeev Redkar, Pasit Phiasivongsa, Chunlin Tang, Roselle Will, Maria Hankewych, Bryan Roxas, Mahipal Singh, Yogen Saunthararajah and Joseph DeSimone

    Version of Record online : 15 AUG 2007, DOI: 10.1002/ajh.21020

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    Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine

    American Journal of Hematology

    Volume 81, Issue 7, July 2006, Pages: 543–545, Amanda F. Cashen, Hollie Devine and John DiPersio

    Version of Record online : 5 JUN 2006, DOI: 10.1002/ajh.20626

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    The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells

    International Journal of Cancer

    Volume 130, Issue 5, 1 March 2012, Pages: 1195–1207, María J. Ruiz-Magaña, Jose M. Rodríguez-Vargas, Jorge C. Morales, Manuel A. Saldivia, Klaus Schulze-Osthoff and Carmen Ruiz-Ruiz

    Version of Record online : 21 JUL 2011, DOI: 10.1002/ijc.26107

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    The combination of hypomethylating agents and histone deacetylase inhibitors produce marked synergy in preclinical models of T-cell lymphoma

    British Journal of Haematology

    Volume 171, Issue 2, October 2015, Pages: 215–226, Enrica Marchi, Kelly M. Zullo, Jennifer E. Amengual, Matko Kalac, Danielle Bongero, Christine M. McIntosh, Laura K. Fogli, Maura Rossi, Pier L. Zinzani, Stefano A. Pileri, Pier P. Piccaluga, Fabio Fuligni, Luigi Scotto and Owen A. O'Connor

    Version of Record online : 20 JUL 2015, DOI: 10.1111/bjh.13566

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    A phase 1 clinical trial of vorinostat in combination with decitabine in patients with acute myeloid leukaemia or myelodysplastic syndrome

    British Journal of Haematology

    Volume 167, Issue 2, October 2014, Pages: 185–193, Mark Kirschbaum, Ivana Gojo, Stuart L. Goldberg, Christopher Bredeson, Lisa A. Kujawski, Allen Yang, Peter Marks, Paul Frankel, Xing Sun, Alessandra Tosolini, Joseph E. Eid, Gregory M. Lubiniecki and Jean-Pierre Issa

    Version of Record online : 8 JUL 2014, DOI: 10.1111/bjh.13016