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There are 16080 results for: content related to: Childhood leukaemia: a relationship between intracellular 6- mercaptopurine metabolites and neutropenia.

  1. Erythrocyte mean corpuscular volume as a surrogate marker for 6-thioguanine nucleotide concentration monitoring in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine

    Inflammatory Bowel Diseases

    Volume 9, Issue 4, July 2003, Pages: 237–245, Carlton W. Thomas Jr., Philip W. Lowry, Curtis L. Franklin, Amy L. Weaver, Gennett M. Myhre, Dennis C. Mays, William J. Tremaine, James J. Lipsky and William J. Sandborn

    Version of Record online : 14 DEC 2006, DOI: 10.1097/00054725-200307000-00004

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    Enhanced bioavailability of azathioprine compared to 6-mercaptopurine therapy in inflammatory bowel disease: correlation with treatment efficacy

    Alimentary Pharmacology & Therapeutics

    Volume 14, Issue 8, August 2000, Pages: 1009–1014, C. Cuffari, S. Hunt and T. M. Bayless

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2036.2000.00812.x

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    Biotransformation of 6-thioguanine in inflammatory bowel disease patients: a comparison of oral and intravenous administration of 6-thioguanine

    British Journal of Pharmacology

    Volume 163, Issue 4, June 2011, Pages: 722–731, B Jharap, NKH de Boer, RM Vos, K Smid, A Zwiers, GJ Peters, CJJ Mulder, AJ Wilhelm and AA van Bodegraven

    Version of Record online : 26 MAY 2011, DOI: 10.1111/j.1476-5381.2011.01265.x

  4. Extended Thiopurine Metabolite Assessment During 6-Thioguanine Therapy for Immunomodulation in Crohn's Disease

    The Journal of Clinical Pharmacology

    Volume 47, Issue 2, February 2007, Pages: 187–191, N. K. H. de Boer, L. J. J. Derijks, J. J. Keizer-Garritsen, L. H. J. Lambooy, W. Ruitenbeek, P. M. Hooymans, A. A. van Bodegraven and D. J. de Jong

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270006294403

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    Azathioprine metabolism in kidney transplant recipients.

    British Journal of Clinical Pharmacology

    Volume 18, Issue 5, November 1984, Pages: 693–700, L Lennard, CB Brown, M Fox and JL Maddocks

    Version of Record online : 26 JUL 2012, DOI: 10.1111/j.1365-2125.1984.tb02531.x

  6. Indicators of clinical response to treatment with six-mercaptopurine or azathioprine in patients with inflammatory bowel disease

    Inflammatory Bowel Diseases

    Volume 10, Issue 4, July 2004, Pages: 339–345, Jean-Paul Achkar, Tyler Stevens, Kirk Easley, Aaron Brzezinski, Douglas Seidner and Bret Lashner

    Version of Record online : 14 DEC 2006, DOI: 10.1097/00054725-200407000-00003

  7. Monitoring 6-thioguanine nucleotide concentrations in Japanese children and adolescents with inflammatory bowel disease

    Journal of Gastroenterology and Hepatology

    Volume 25, Issue 10, October 2010, Pages: 1626–1630, Yoshikazu Ohtsuka, Katsuhiro Arai, Yo Aoyagi, Tohru Fujii, Yoko Yamakawa, Kiyotaka Ohtani, Tamaki Ikuse, Yosuke Baba, Eisuke Inage, Takahiro Kudo, Ryuyo Suzuki, Satoru Nagata and Toshiaki Shimizu

    Version of Record online : 14 MAY 2010, DOI: 10.1111/j.1440-1746.2010.06364.x

  8. 5-Aminosalicylate therapy is associated with higher 6-thioguanine levels in adults and children with inflammatory bowel disease in remission on 6-mercaptopurine or azathioprine

    Inflammatory Bowel Diseases

    Volume 12, Issue 4, April 2006, Pages: 251–257, Scott Hande, Noah Wilson-Rich, Athos Bousvaros, Anna Zholudev, Rie Maurer, Peter Banks, Frederick Makrauer, Sarathchandra Reddy, Robert Burakoff and Sonia Friedman

    Version of Record online : 14 DEC 2006, DOI: 10.1097/01.MIB.0000206544.05661.9f

  9. An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy

    Inflammatory Bowel Diseases

    Volume 7, Issue 3, August 2001, Pages: 181–189, Dr. Marla C. Dubinsky, Philip V. Hassard, Dr. Ernest G. Seidman, Lori Y. Kam, Maria T. Abreu, Dr. Stephan R. Targan and Eric A. Vasiliauskas

    Version of Record online : 14 DEC 2006, DOI: 10.1097/00054725-200108000-00001

  10. Assay of 6-thioguanine nucleotide, a major metabolite of azathioprine, 6-mercaptopurine and 6-thioguanine, in human red blood cells

    Journal of Pharmacy and Pharmacology

    Volume 35, Issue 1, January 1983, Pages: 15–18, L. LENNARD and J. L. MADDOCKS

    Version of Record online : 12 APR 2011, DOI: 10.1111/j.2042-7158.1983.tb04255.x

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    Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy

    British Journal of Pharmacology

    Volume 160, Issue 5, July 2010, Pages: 1083–1091, P de Graaf, NKH de Boer, DR Wong, S Karner, B Jharap, PM Hooymans, AI Veldkamp, CJJ Mulder, AA van Bodegraven and M Schwab

    Version of Record online : 5 MAR 2010, DOI: 10.1111/j.1476-5381.2010.00731.x

  12. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice

    Internal Medicine Journal

    Volume 35, Issue 10, October 2005, Pages: 580–585, R. B. Gearry, 1,2 M. L. Barclay, 1,2,3 R. L. Roberts, 4 J. Harraway, 5 M. Zhang, 3,5 L. S. Pike, 5 P. M. George and 5 C. M. Florkowski 5

    Version of Record online : 6 OCT 2005, DOI: 10.1111/j.1445-5994.2005.00904.x

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    6-Thioguanine in children with acute lymphoblastic leukaemia: influence of food on parent drug pharmacokinetics and 6-thioguanine nucleotide concentrations

    British Journal of Clinical Pharmacology

    Volume 51, Issue 6, June 2001, Pages: 531–539, D. L. Lancaster, N. Patel, L. Lennard and J. S. Lilleyman

    Version of Record online : 24 JAN 2002, DOI: 10.1046/j.0306-5251.2001.01391.x

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    Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease

    Journal of Gastroenterology and Hepatology

    Volume 20, Issue 8, August 2005, Pages: 1149–1157, RICHARD B GEARRY and MURRAY L BARCLAY

    Version of Record online : 11 MAY 2005, DOI: 10.1111/j.1440-1746.2005.03832.x

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    Thioguanine-nucleotides do not predict efficacy of tioguanine in Crohn's disease

    Alimentary Pharmacology & Therapeutics

    Volume 19, Issue 12, June 2004, Pages: 1269–1276, K. R. Herrlinger, K. Fellermann, C. Fischer, W. Kreisel, P. Deibert, J. Schoelmerich, W. E. Fleig, A. Ruhl, M. Reinshagen, R. Greinwald, E. F. Stange and M. Schwab

    Version of Record online : 4 JUN 2004, DOI: 10.1111/j.1365-2036.2004.01947.x

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    Physiologically based pharmacokinetic model for 6-mercpatopurine: exploring the role of genetic polymorphism in TPMT enzyme activity

    British Journal of Clinical Pharmacology

    Volume 80, Issue 1, July 2015, Pages: 86–100, Kayode Ogungbenro, Leon Aarons and the CRESim & Epi-CRESim Project Groups

    Version of Record online : 1 JUN 2015, DOI: 10.1111/bcp.12588

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    Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 66, Issue 6, December 2008, Pages: 826–837, Ahmed F. Hawwa, Paul S. Collier, Jeff S. Millership, Anthony McCarthy, Sid Dempsey, Carole Cairns and James C. McElnay

    Version of Record online : 15 AUG 2008, DOI: 10.1111/j.1365-2125.2008.03281.x

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    The impact of introducing thioguanine nucleotide monitoring into an inflammatory bowel disease clinic

    International Journal of Clinical Practice

    Volume 67, Issue 2, February 2013, Pages: 161–169, M. Smith, P. Blaker, C. Patel, A. Marinaki, M. Arenas, E. Escuredo, S. Anderson, P. Irving and J. Sanderson

    Version of Record online : 17 DEC 2012, DOI: 10.1111/ijcp.12039

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    Hypoxanthine guanine phosphoribosyltransferase activity is related to 6-thioguanine nucleotide concentrations and thiopurine-induced leukopenia in the treatment of inflammatory bowel disease

    Inflammatory Bowel Diseases

    Volume 18, Issue 1, January 2012, Pages: 63–73, Liang Ding, Fang-bin Zhang, Hui Liu, Xiang Gao, Hui-chang Bi, Xue-ding Wang, Bai-li Chen, Yu Zhang, Li-zi Zhao, Guo-ping Zhong, Pin-jin Hu, Min-hu Chen and Ming Huang

    Version of Record online : 4 MAR 2011, DOI: 10.1002/ibd.21676

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    Remission maintenance for acute nonlymphocytic leukemia cytosine arabinoside plus 6-thioguanine versus a sequence of drug regimens

    Cancer

    Volume 46, Issue 1, 1 July 1980, Pages: 22–28, Gary A. Presant, Nathan A. Berger, Carol Klahr and Gordon L. Phillips

    Version of Record online : 28 JUN 2006, DOI: 10.1002/1097-0142(19800701)46:1<22::AID-CNCR2820460104>3.0.CO;2-P