Search Results

There are 9297 results for: content related to: Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother-infant pairs

  1. You have free access to this content
    Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy

    British Journal of Pharmacology

    Volume 160, Issue 5, July 2010, Pages: 1083–1091, P de Graaf, NKH de Boer, DR Wong, S Karner, B Jharap, PM Hooymans, AI Veldkamp, CJJ Mulder, AA van Bodegraven and M Schwab

    Article first published online : 5 MAR 2010, DOI: 10.1111/j.1476-5381.2010.00731.x

  2. Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice

    Internal Medicine Journal

    Volume 35, Issue 10, October 2005, Pages: 580–585, R. B. Gearry, 1,2 M. L. Barclay, 1,2,3 R. L. Roberts, 4 J. Harraway, 5 M. Zhang, 3,5 L. S. Pike, 5 P. M. George and 5 C. M. Florkowski 5

    Article first published online : 6 OCT 2005, DOI: 10.1111/j.1445-5994.2005.00904.x

  3. You have free access to this content
    Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 125–136, Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M. Richards and Ajay Vora

    Article first published online : 20 JUN 2013, DOI: 10.1111/bcp.12066

  4. You have full text access to this OnlineOpen article
    Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics

    British Journal of Haematology

    Volume 169, Issue 2, April 2015, Pages: 228–240, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Article first published online : 29 NOV 2014, DOI: 10.1111/bjh.13240

  5. You have free access to this content
    High TPMT enzyme activity does not explain drug resistance due to preferential 6-methylmercaptopurine production in patients on thiopurine treatment

    Alimentary Pharmacology & Therapeutics

    Volume 35, Issue 10, May 2012, Pages: 1181–1189, R. van Egmond, P. Chin, M. Zhang, C. W. Sies and M. L. Barclay

    Article first published online : 4 APR 2012, DOI: 10.1111/j.1365-2036.2012.05084.x

  6. Genetic Polymorphism of Inosine Triphosphate Pyrophosphatase Is a Determinant of Mercaptopurine Metabolism and Toxicity During Treatment for Acute Lymphoblastic Leukemia

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 2, February 2009, Pages: 164–172, G Stocco, MH Cheok, KR Crews, T Dervieux, D French, D Pei, W Yang, C Cheng, C-H Pui, MV Relling and WE Evans

    Article first published online : 6 AUG 2008, DOI: 10.1038/clpt.2008.154

  7. You have free access to this content
    Biotransformation of 6-thioguanine in inflammatory bowel disease patients: a comparison of oral and intravenous administration of 6-thioguanine

    British Journal of Pharmacology

    Volume 163, Issue 4, June 2011, Pages: 722–731, B Jharap, NKH de Boer, RM Vos, K Smid, A Zwiers, GJ Peters, CJJ Mulder, AJ Wilhelm and AA van Bodegraven

    Article first published online : 26 MAY 2011, DOI: 10.1111/j.1476-5381.2011.01265.x

  8. Physiologically based pharmacokinetic model for 6-mercpatopurine: exploring the role of genetic polymorphism in TPMT enzyme activity

    British Journal of Clinical Pharmacology

    Volume 80, Issue 1, July 2015, Pages: 86–100, Kayode Ogungbenro, Leon Aarons and the CRESim & Epi-CRESim Project Groups

    Article first published online : 1 JUN 2015, DOI: 10.1111/bcp.12588

  9. You have free access to this content
    Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy

    British Journal of Clinical Pharmacology

    Volume 71, Issue 4, April 2011, Pages: 575–584, Tiphaine Adam de Beaumais, May Fakhoury, Yves Medard, Said Azougagh, Daolun Zhang, Karima Yakouben and Evelyne Jacqz-Aigrain

    Article first published online : 11 MAR 2011, DOI: 10.1111/j.1365-2125.2010.03867.x

  10. You have free access to this content
    Thiopurine metabolism monitoring: implications in inflammatory bowel diseases

    European Journal of Clinical Investigation

    Volume 40, Issue 11, November 2010, Pages: 1037–1047, Olivier Dewit, Peter Starkel and Xavier Roblin

    Article first published online : 19 AUG 2010, DOI: 10.1111/j.1365-2362.2010.02346.x

  11. You have full text access to this OnlineOpen article
    Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

    British Journal of Haematology

    Volume 170, Issue 4, August 2015, Pages: 550–558, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Article first published online : 5 MAY 2015, DOI: 10.1111/bjh.13469

  12. You have free access to this content
    Implementation of TPMT testing

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 704–714, Lynne Lennard

    Article first published online : 20 MAR 2014, DOI: 10.1111/bcp.12226

  13. You have free access to this content
    IMPDH activity in thiopurine-treated patients with inflammatory bowel disease – relation to TPMT activity and metabolite concentrations

    British Journal of Clinical Pharmacology

    Volume 65, Issue 1, January 2008, Pages: 69–77, Sofie Haglund, Jan Taipalensuu, Curt Peterson and Sven Almer

    Article first published online : 27 JUL 2007, DOI: 10.1111/j.1365-2125.2007.02985.x

  14. You have free access to this content
    Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine

    British Journal of Clinical Pharmacology

    Volume 66, Issue 4, October 2008, Pages: 517–528, Ahmed F. Hawwa, Jeff S. Millership, Paul S. Collier, Koen Vandenbroeck, Anthony McCarthy, Sid Dempsey, Carole Cairns, John Collins, Colin Rodgers and James C. McElnay

    Article first published online : 28 JUN 2008, DOI: 10.1111/j.1365-2125.2008.03248.x

  15. Influence of the variable number of tandem repeats located in the promoter region of the thiopurine methyltransferase gene on enzymatic activity

    Clinical Pharmacology & Therapeutics

    Volume 70, Issue 2, August 2001, Pages: 165–174, Sandra Alves, António Amorim, Fátima Ferreira and Maria João Prata

    Article first published online : 11 AUG 2001, DOI: 10.1067/mcp.2001.117284

  16. You have free access to this content
    British Association of Dermatologists’ guidelines for the safe and effective prescribing of azathioprine 2011

    British Journal of Dermatology

    Volume 165, Issue 4, October 2011, Pages: 711–734, S.J. Meggitt, A.V. Anstey, M.F. Mohd Mustapa, N.J. Reynolds and S. Wakelin

    Article first published online : 27 SEP 2011, DOI: 10.1111/j.1365-2133.2011.10575.x

  17. You have free access to this content
    Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine

    British Journal of Clinical Pharmacology

    Volume 48, Issue 6, December 1999, Pages: 793–800, Dervieux, Médard, Baudouin, Maisin, Zhang, Broly, Loirat and Jacqz-Aigrain

    Article first published online : 24 DEC 2001, DOI: 10.1046/j.1365-2125.1999.00087.x

  18. You have free access to this content
    Tracing the Origin of the Most Common Thiopurine Methyltransferase (TPMT) Variants: Preliminary Data from the Patterns of Haplotypic Association with Two CA Repeats

    Annals of Human Genetics

    Volume 68, Issue 4, July 2004, Pages: 313–323, S. Alves, J. Rocha, A. Amorim and M. J. Prata

    Article first published online : 28 JUN 2004, DOI: 10.1046/j.1529-8817.2004.00104.x

  19. Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia—The Influence of Thiopurine Methyltransferase Genotypes

    The Journal of Clinical Pharmacology

    Volume 53, Issue 6, June 2013, Pages: 670–674, Maria S. Ebbesen, Jacob Nersting, Jack H. Jacobsen, Thomas L. Frandsen, Kim Vettenranta, Jonas Abramsson, Finn Wesenberg and Kjeld Schmiegelow

    Article first published online : 15 APR 2013, DOI: 10.1002/jcph.81

  20. Thiopurine S-methyltransferase gene polymorphism in Japanese patients with autoimmune liver diseases

    Liver International

    Volume 27, Issue 1, February 2007, Pages: 95–100, Akihiro Tamori, Mayumi Shinzaki, Saori Kosaka, Takehiro Hayashi, Shuji Iwai, Masaru Enomoto, Daiki Habu, Hiroki Sakaguchi, Norifumi Kawada, Masayuki Hino, Susumu Shiomi and Shuhei Nishiguchi

    Article first published online : 6 DEC 2006, DOI: 10.1111/j.1478-3231.2006.01392.x