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There are 7800 results for: content related to: Pharmacokinetic and clinical profile of a novel formulation of bosentan in children with pulmonary arterial hypertension: the FUTURE-1 study

  1. Clinical Pharmacokinetics and Drug-Drug Interactions of Endothelin Receptor Antagonists in Pulmonary Arterial Hypertension

    The Journal of Clinical Pharmacology

    Volume 52, Issue 12, December 2012, Pages: 1784–1805, Dr Jürgen Venitz, Dr Julia Zack, Dr Hunter Gillies, Dr Martine Allard, Ms Jean Regnault and Dr Christopher Dufton

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270011423662

  2. You have free access to this content
    Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers

    British Journal of Clinical Pharmacology

    Volume 77, Issue 1, January 2014, Pages: 141–148, Christoph Markert, Yvonne Schweizer, Regina Hellwig, Theresia Wirsching, Klaus-Dieter Riedel, Juergen Burhenne, Johanna Weiss, Gerd Mikus and Walter E. Haefeli

    Version of Record online : 20 DEC 2013, DOI: 10.1111/bcp.12177

  3. The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: A potential mechanism for hepatic adverse reactions

    Clinical Pharmacology & Therapeutics

    Volume 69, Issue 4, April 2001, Pages: 223–231, Karin Fattinger, Christoph Funk, Michael Pantze, Cornelia Weber, Jürg Reichen, Bruno Stieger and Peter J. Meier

    Version of Record online : 2 APR 2001, DOI: 10.1067/mcp.2001.114667

  4. Key Articles and Guidelines in the Management of Pulmonary Arterial Hypertension: 2011 Update

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 32, Issue 6, June 2012, Pages: e134–e169, Samuel G. Johnson, Steven R. Kayser, Rebecca L. Attridge, Laura Duvall, Tyree H. Kiser, Rebecca Moote, Brent N. Reed, Jo E. Rodgers and Brian Erstad

    Version of Record online : 30 MAR 2012, DOI: 10.1002/j.1875-9114.2012.01105.x

  5. Pharmacokinetic Interaction Between Tadalafil and Bosentan in Healthy Male Subjects

    The Journal of Clinical Pharmacology

    Volume 48, Issue 5, May 2008, Pages: 610–618, Dr Rebecca E. Wrishko, Dr Jasper Dingemanse, Dr Albert Yu, Ms Christelle Darstein, Dr Diane L. Phillips and Mr Malcolm I. Mitchell

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008315315

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    Pharmacokinetic interactions among imatinib, bosentan and sildenafil, and their clinical implications in severe pulmonary arterial hypertension

    British Journal of Clinical Pharmacology

    Volume 80, Issue 1, July 2015, Pages: 75–85, Didier Renard, Thomas Bouillon, Ping Zhou, Gerard Flesch and Debbie Quinn

    Version of Record online : 1 JUN 2015, DOI: 10.1111/bcp.12584

  7. Influence of Mild Liver Impairment on the Pharmacokinetics and Metabolism of Bosentan, a Dual Endothelin Receptor Antagonist

    The Journal of Clinical Pharmacology

    Volume 43, Issue 1, January 2003, Pages: 15–22, Paul L. M. van Giersbergen, Gabriela Popescu, Frédéric Bodin and Jasper Dingemanse

    Version of Record online : 8 MAR 2013, DOI: 10.1177/0091270002239701

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    Single- and multiple-dose pharmacokinetics of bosentan and its interaction with ketoconazole

    British Journal of Clinical Pharmacology

    Volume 53, Issue 6, June 2002, Pages: 589–595, Paul L. M. van Giersbergen, Atef Halabi and Jasper Dingemanse

    Version of Record online : 24 JUN 2002, DOI: 10.1046/j.1365-2125.2002.01608.x

  9. You have free access to this content
    Endothelin receptor antagonists for pulmonary arterial hypertension

    Intervention Review

    The Cochrane Library

    Chao Liu, Junmin Chen, Yanqiu Gao, Bao Deng and Kunshen Liu

    Published Online : 28 FEB 2013, DOI: 10.1002/14651858.CD004434.pub5

  10. Association of CYP2C9*2 With Bosentan-Induced Liver Injury

    Clinical Pharmacology & Therapeutics

    Volume 94, Issue 6, December 2013, Pages: 678–686, S M Markova, T De Marco, N Bendjilali, E A Kobashigawa, J Mefford, J Sodhi, H Le, C Zhang, J Halladay, A E Rettie, C Khojasteh, D McGlothlin, A H B Wu, W-C Hsueh, J S Witte, J B Schwartz and D L Kroetz

    Version of Record online : 17 JUL 2013, DOI: 10.1038/clpt.2013.143

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    Endothelin Receptor Blockade Ameliorates Vascular Fragility in Endothelial Cell–Specific Fli-1–Knockout Mice by Increasing Fli-1 DNA Binding Ability

    Arthritis & Rheumatology

    Volume 67, Issue 5, May 2015, Pages: 1335–1344, Kaname Akamata, Yoshihide Asano, Takashi Yamashita, Shinji Noda, Takashi Taniguchi, Takehiro Takahashi, Yohei Ichimura, Tetsuo Toyama, Maria Trojanowska and Shinichi Sato

    Version of Record online : 27 APR 2015, DOI: 10.1002/art.39062

  12. Acute Hemodynamic Effects of Single-Dose Sildenafil When Added to Established Bosentan Therapy in Patients With Pulmonary Arterial Hypertension: Results of the COMPASS-1 Study

    The Journal of Clinical Pharmacology

    Volume 49, Issue 11, November 2009, Pages: 1343–1352, Dr Ekkehard Gruenig, Dr Evangelos Michelakis, Dr Jean-Luc Vachiéry, Dr Carmine Dario Vizza, Dr F. Joachim Meyer, Dr Martin Doelberg, Dr Doris Bach, Dr Jasper Dingemanse and Dr Nazzareno Galiè

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009341182

  13. Effects of bosentan on nondigital ulcers in patients with systemic sclerosis

    British Journal of Dermatology

    Volume 166, Issue 2, February 2012, Pages: 417–421, T. Taniguchi, Y. Asano, M. Hatano, Z. Tamaki, M. Tomita, T. Kawashima, M. Miyazaki, H. Sumida, K. Akamata, T. Takahashi, Y. Ichimura, T. Toyama, M. Sugita, S. Noda, A. Yao, K. Kinugawa and S. Sato

    Version of Record online : 5 DEC 2011, DOI: 10.1111/j.1365-2133.2011.10581.x

  14. Lack of a Pharmacokinetic Interaction Between Oral Treprostinil and Bosentan in Healthy Adult Volunteers

    The Journal of Clinical Pharmacology

    Volume 50, Issue 7, July 2010, Pages: 829–834, Dr S. Karl Gotzkowsky, Dr Jasper Dingemanse, Dr Allen Lai, Dr David Mottola and Dr Kevin Laliberte

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009351173

  15. Inhibitory and Inductive Effects of Rifampin on the Pharmacokinetics of Bosentan in Healthy Subjects

    Clinical Pharmacology & Therapeutics

    Volume 81, Issue 3, March 2007, Pages: 414–419, P L M van Giersbergen, A Treiber, R Schneiter, H Dietrich and J Dingemanse

    Version of Record online : 24 JAN 2007, DOI: 10.1038/sj.clpt.6100075

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    Impact of bosentan on exercise capacity in adults after the Fontan procedure: a randomized controlled trial

    European Journal of Heart Failure

    Volume 15, Issue 6, June 2013, Pages: 690–698, Mark J. Schuuring, Jeroen C. Vis, Arie P.J. van Dijk, Joost P. van Melle, Hubert W. Vliegen, Petronella G. Pieper, Gertjan T. Sieswerda, Rianne H.A.C.M. de Bruin-Bon, Barbara J.M. Mulder and Berto J. Bouma

    Version of Record online : 27 JAN 2014, DOI: 10.1093/eurjhf/hft017

  17. Systematic review of randomised, double-blind clinical trials of oral agents conducted in patients with pulmonary arterial hypertension

    International Journal of Clinical Practice

    Volume 61, Issue 10, October 2007, Pages: 1756–1765, F. Torres

    Version of Record online : 14 SEP 2007, DOI: 10.1111/j.1742-1241.2007.01545.x

  18. Combination therapy in the management of pulmonary arterial hypertension

    International Journal of Clinical Practice

    Volume 67, Issue s179, May 2013, Pages: 13–23, M. S. Buckley, R. L. Staib and L. M. Wicks

    Version of Record online : 11 APR 2013, DOI: 10.1111/ijcp.12136

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    The effect of bosentan on the pharmacokinetics of digoxin in healthy male subjects

    British Journal of Clinical Pharmacology

    Volume 47, Issue 6, June 1999, Pages: 701–706, Cornelia Weber, Ludger Banken, Herbert Birnboeck, Stephane Nave and Rainer Schulz

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2125.1999.00946.x

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    Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line

    British Journal of Pharmacology

    Volume 169, Issue 1, May 2013, Pages: 21–33, C Fahrmayr, J König, D Auge, M Mieth, K Münch, J Segrestaa, T Pfeifer, A Treiber and MF Fromm

    Version of Record online : 12 APR 2013, DOI: 10.1111/bph.12126