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There are 21556 results for: content related to: Inhibition of oral midazolam clearance by boosting doses of ritonavir, and by 4,4-dimethyl-benziso-(2H)-selenazine (ALT-2074), an experimental catalytic mimic of glutathione oxidase

  1. Mechanism of Ritonavir Changes in Methadone Pharmacokinetics and Pharmacodynamics: I. Evidence Against CYP3A Mediation of Methadone Clearance

    Clinical Pharmacology & Therapeutics

    Volume 84, Issue 4, October 2008, Pages: 497–505, ED Kharasch, PS Bedynek, S Park, D Whittington, A Walker and C Hoffer

    Article first published online : 9 JUL 2008, DOI: 10.1038/clpt.2008.104

  2. Mechanisms of Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Ritonavir-Enhanced Tipranavir

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 27, Issue 6, June 2007, Pages: 888–909, Dr. Manoli Vourvahis and Dr. Angela D. M. Kashuba

    Article first published online : 6 JAN 2012, DOI: 10.1592/phco.27.6.888

  3. Lack of Interaction between Enfuvirtide and Ritonavir or Ritonavir-Boosted Saquinavir in HIV-1-Infected Patients

    The Journal of Clinical Pharmacology

    Volume 44, Issue 7, July 2004, Pages: 793–802, Dr. Kiat Ruxrungtham, Mr. Mark Boyd, Dr. S. Eralp Bellibas, Dr. Xiaoping Zhang, Dr. Albert Dorr, Mr. Stanley Kolis, Dr. Tosca Kinchelow, Dr. Neil Buss and Dr. Indravadan H. Patel

    Article first published online : 8 MAR 2013, DOI: 10.1177/0091270004266489

  4. You have free access to this content
    Model-based approach to dose optimization of lopinavir/ritonavir when co-administered with rifampicin

    British Journal of Clinical Pharmacology

    Volume 73, Issue 5, May 2012, Pages: 758–767, Chao Zhang, Paolo Denti, Eric Decloedt, Gary Maartens, Mats O. Karlsson, Ulrika S. H. Simonsson and Helen McIlleron

    Article first published online : 5 APR 2012, DOI: 10.1111/j.1365-2125.2011.04154.x

  5. Practical Perspectives on the Use of Tipranavir in Combination With Other Medications: Lessons Learned From Pharmacokinetic Studies

    The Journal of Clinical Pharmacology

    Volume 46, Issue 2, February 2006, Pages: 130–139, Marta Boffito, Desmond Maitland and Anton Pozniak

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270005283279

  6. Time-Dependent Interaction Between Lopinavir/Ritonavir and Fexofenadine

    The Journal of Clinical Pharmacology

    Volume 46, Issue 7, July 2006, Pages: 758–767, P. G. Rolf, Dr van Heeswijk, Mr Marc Bourbeau, Ms Pearl Campbell, Ms Isabelle Seguin, Mr Bobby M. Chauhan, Dr Brian C. Foster and Dr D. William Cameron

    Article first published online : 8 MAR 2013, DOI: 10.1177/0091270006288733

  7. Steady-State Pharmacokinetics of Etravirine and Lopinavir/Ritonavir Melt Extrusion Formulation, Alone and in Combination, in Healthy HIV-Negative Volunteers

    The Journal of Clinical Pharmacology

    Volume 53, Issue 2, February 2013, Pages: 202–210, Monika Schöller-Gyüre, Thomas N. Kakuda, James Witek, Sophie H. Akuma, Goedele De Smedt, Kurt Spittaels, Veerle Vyncke and Richard M.W. Hoetelmans

    Article first published online : 24 JAN 2013, DOI: 10.1177/0091270012445205

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    Enhanced Boosting of Oral Absorption of Lopinavir Through Electrospray Coencapsulation with Ritonavir

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 9, September 2015, Pages: 2977–2985, Shinji Sakuma, Satoshi Matsumoto, Narimoto Ishizuka, Kohta Mohri, Mayuko Fukushima, Chie Ohba and Kohsaku Kawakami

    Article first published online : 18 MAY 2015, DOI: 10.1002/jps.24492

  9. Mechanism of Ritonavir Changes in Methadone Pharmacokinetics and Pharmacodynamics: II. Ritonavir Effects on CYP3A and P-Glycoprotein Activities

    Clinical Pharmacology & Therapeutics

    Volume 84, Issue 4, October 2008, Pages: 506–512, ED Kharasch, PS Bedynek, A Walker, D Whittington and C Hoffer

    Article first published online : 9 JUL 2008, DOI: 10.1038/clpt.2008.102

  10. Short-Term Exposure to Low-Dose Ritonavir Impairs Clearance and Enhances Adverse Effects of Trazodone

    The Journal of Clinical Pharmacology

    Volume 43, Issue 4, April 2003, Pages: 414–422, David J. Greenblatt, Lisa L. von Moltke, Jerold S. Harmatz, Steven M. Fogelman, Gengsheng Chen, Jennifer A. Graf, Polyxane Mertzanis, Susan Byron, Kerry E. Culm, Brian W. Granda, Johanna P. Daily and Richard I. Shader

    Article first published online : 8 MAR 2013, DOI: 10.1177/0091270003251864

  11. Dose–Response of Ritonavir on Hepatic CYP3A Activity and Elvitegravir Oral Exposure

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 1, January 2009, Pages: 64–70, AA Mathias, S West, J Hui and BP Kearney

    Article first published online : 24 SEP 2008, DOI: 10.1038/clpt.2008.168

  12. Thorough QT/QTc Study of Ritonavir-Boosted Saquinavir Following Multiple-Dose Administration of Therapeutic and Supratherapeutic Doses in Healthy Participants

    The Journal of Clinical Pharmacology

    Volume 52, Issue 4, April 2012, Pages: 520–529, Dr Xiaoping Zhang, Dr Paul Jordan, Ms Laura Cristea, Dr Miklos Salgo, Ms Rana Farha, Mr Stanley Kolis and Dr Lois S. Lee

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270011400071

  13. Unbound Ritonavir Concentrations in Rat and Human Hepatocytes

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 7, July 2015, Pages: 2378–2387, Janneke Keemink, Patrick Augustijns and Pieter Annaert

    Article first published online : 18 MAY 2015, DOI: 10.1002/jps.24477

  14. You have free access to this content
    Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer

    British Journal of Clinical Pharmacology

    Volume 69, Issue 5, May 2010, Pages: 465–474, Stijn L. W. Koolen, Roos L. Oostendorp, Jos H. Beijnen, Jan H. M. Schellens and Alwin D. R. Huitema

    Article first published online : 28 JAN 2010, DOI: 10.1111/j.1365-2125.2010.03621.x

  15. Effect of Low-Dose Omeprazole (20 mg Daily) on the Pharmacokinetics of Multiple-Dose Atazanavir With Ritonavir in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 51, Issue 3, March 2011, Pages: 368–377, Li Zhu, Anna Persson, Lisa Mahnke, Timothy Eley, Tong Li, Xiaohui Xu, Sangeeta Agarwala, Jeffrey Dragone and Richard Bertz

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270010367651

  16. Steady-State Pharmacokinetic Interactions of Darunavir/Ritonavir With Lipid-Lowering Agent Rosuvastatin

    The Journal of Clinical Pharmacology

    Volume 52, Issue 6, June 2012, Pages: 922–931, Ms Divya Samineni, Dr Pankaj B. Desai, Dr Larry Sallans and Dr Carl J. Fichtenbaum

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270011407494

  17. Interactions Between Amprenavir and the Lopinavir-ritonavir Combination in Heavily Pretreated Patients Infected with Human Immunodeficiency Virus

    Clinical Pharmacology & Therapeutics

    Volume 75, Issue 4, April 2004, Pages: 310–323, Anne-Marie Taburet, Gilles Raguin, Clotilde Le Tiec, Cécile Droz, Aurélie Barrail, Isabelle Vincent, Laurence Morand-Joubert, Geneviève Chêne, François Clavel and Pierre-Marie Girard

    Article first published online : 8 APR 2004, DOI: 10.1016/j.clpt.2003.12.013

  18. Ritonavir inhibits intratumoral docetaxel metabolism and enhances docetaxel antitumor activity in an immunocompetent mouse breast cancer model

    International Journal of Cancer

    Volume 138, Issue 3, 1 February 2016, Pages: 758–769, Jeroen J.M.A. Hendrikx, Jurjen S. Lagas, Ji-Ying Song, Hilde Rosing, Jan H.M. Schellens, Jos H. Beijnen, Sven Rottenberg and Alfred H. Schinkel

    Article first published online : 21 SEP 2015, DOI: 10.1002/ijc.29812

  19. Pharmacokinetics and Safety of the Lopinavir/Ritonavir Tablet 500/125 mg Twice Daily Coadministered With Efavirenz in Healthy Adult Participants

    The Journal of Clinical Pharmacology

    Volume 52, Issue 8, August 2012, Pages: 1248–1254, Juki Ng, Yi-Lin Chiu, Walid Awni, Barry Bernstein, Sonja J. Causemaker and Cheri E. Klein

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270011410568

  20. Pharmacokinetics of Lopinavir/Ritonavir in HIV/Hepatitis C Virus–Coinfected Subjects With Hepatic Impairment

    The Journal of Clinical Pharmacology

    Volume 46, Issue 3, March 2006, Pages: 265–274, Dr Joanna Z. Peng, Dr Federico Pulido, Ms Sonja J. Kemmis Causemaker, Ms Jianling Li, Dr Alicia Lorenzo, Dr Concepción Cepeda, Dr Juan A. García Cabanillas, Dr Barbara DaSilva, Dr Scott C. Brun and Dr José Arribas

    Article first published online : 8 MAR 2013, DOI: 10.1177/0091270005284853