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There are 12830 results for: content related to: Impact of the CYP2C8 * 3 polymorphism on the drug–drug interaction between gemfibrozil and pioglitazone

  1. Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro

    Biopharmaceutics & Drug Disposition

    Volume 34, Issue 5, July 2013, Pages: 278–287, Lushan Yu, Da Shi, Liping Ma, Quan Zhou and Su Zeng

    Version of Record online : 3 JUN 2013, DOI: 10.1002/bdd.1842

  2. Gemfibrozil Is a Strong Inactivator of CYP2C8 in Very Small Multiple Doses

    Clinical Pharmacology & Therapeutics

    Volume 91, Issue 5, May 2012, Pages: 846–855, J Honkalammi, M Niemi, P J Neuvonen and J T Backman

    Version of Record online : 4 APR 2012, DOI: 10.1038/clpt.2011.313

  3. Cytochrome P450 2C8: Substrates, Inhibitors, Pharmacogenetics, and Clinical Relevance

    Clinical Pharmacology & Therapeutics

    Volume 77, Issue 5, May 2005, Pages: 341–352, Rheem A. Totah and Allan E. Rettie

    Version of Record online : 16 MAY 2005, DOI: 10.1016/j.clpt.2004.12.267

    Corrected by:

    Correction: Correction

    Vol. 78, Issue 2, 153, Version of Record online: 11 AUG 2005

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    Functional Characterization of CYP2C8.13 and CYP2C8.14: Catalytic Activities toward Paclitaxel

    Basic & Clinical Pharmacology & Toxicology

    Volume 107, Issue 1, July 2010, Pages: 565–569, Nobumitsu Hanioka, Kimiaki Matsumoto, Yoshiro Saito and Shizuo Narimatsu

    Version of Record online : 10 FEB 2010, DOI: 10.1111/j.1742-7843.2010.00543.x

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    Preemptive Genotyping of CYP2C8 and CYP2C9 Allelic Variants Involved in NSAIDs Metabolism for Sickle Cell Disease Pain Management

    Clinical and Translational Science

    Volume 8, Issue 4, August 2015, Pages: 272–280, Cheedy Jaja, Latanya Bowman, Leigh Wells, Niren Patel, Hongyan Xu, Matt Lyon and Abdullah Kutlar

    Version of Record online : 2 FEB 2015, DOI: 10.1111/cts.12260

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    The effects of human CYP2C8 genotype and fluvoxamine on the pharmacokinetics of rosiglitazone in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 62, Issue 6, December 2006, Pages: 682–689, Rasmus S. Pedersen, Per Damkier and Kim Brosen

    Version of Record online : 12 JUL 2006, DOI: 10.1111/j.1365-2125.2006.02706.x

  7. Gemfibrozil Markedly Increases the Plasma Concentrations of Montelukast: A Previously Unrecognized Role for CYP2C8 in the Metabolism of Montelukast

    Clinical Pharmacology & Therapeutics

    Volume 88, Issue 2, August 2010, Pages: 223–230, T Karonen, A Filppula, J Laitila, M Niemi, P J Neuvonen and J T Backman

    Version of Record online : 30 JUN 2010, DOI: 10.1038/clpt.2010.73

  8. Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide

    Clinical Pharmacology & Therapeutics

    Volume 74, Issue 4, October 2003, Pages: 380–387, Mikko Niemi, Julian B. Leathart, Mikko Neuvonen, Janne T. Backman, Ann K. Daly and Pertti J. Neuvonen

    Version of Record online : 11 NOV 2003, DOI: 10.1016/S0009-9236(03)00228-5

  9. Pharmacokinetics and pharmacodynamics of rosiglitazone in relation to CYP2C8 genotype

    Clinical Pharmacology & Therapeutics

    Volume 80, Issue 6, December 2006, Pages: 657–667, Julia Kirchheiner, Soju Thomas, Steffen Bauer, Dorota Tomalik-Scharte, Ursula Hering, Oxana Doroshyenko, Alexander Jetter, Simone Stehle, Martina Tsahuridu, Ingolf Meineke, Jürgen Brockmöller and Uwe Fuhr

    Version of Record online : 15 DEC 2006, DOI: 10.1016/j.clpt.2006.09.008

  10. Mechanism-Based Inactivation of CYP2C8 by Gemfibrozil Occurs Rapidly in Humans

    Clinical Pharmacology & Therapeutics

    Volume 89, Issue 4, April 2011, Pages: 579–586, J Honkalammi, M Niemi, PJ Neuvonen and JT Backman

    Version of Record online : 2 MAR 2011, DOI: 10.1038/clpt.2010.358

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    The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 59, Issue 1, January 2005, Pages: 62–68, Carmen Martínez, Elena García-Martín, Gerardo Blanco, Francisco J. G. Gamito, José M. Ladero and José A. G. Agúndez

    Version of Record online : 27 JUL 2004, DOI: 10.1111/j.1365-2125.2004.02183.x

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    The xenobiotic inhibitor profile of cytochrome P4502C8

    British Journal of Clinical Pharmacology

    Volume 50, Issue 6, December 2000, Pages: 573–580, Chin-Eng Ong, Sally Coulter, Donald J. Birkett, C. Ramana Bhasker and John O. Miners

    Version of Record online : 9 OCT 2008, DOI: 10.1046/j.1365-2125.2000.00316.x

  13. Examination of 209 Drugs for Inhibition of Cytochrome P450 2C8

    The Journal of Clinical Pharmacology

    Volume 45, Issue 1, January 2005, Pages: 68–78, Robert L. Walsky, Emily A. Gaman and R. Scott Obach

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270004270642

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    Pioglitazone is Metabolised by CYP2C8 and CYP3A4 in vitro: Potential for Interactions with CYP2C8 Inhibitors

    Basic & Clinical Pharmacology & Toxicology

    Volume 99, Issue 1, July 2006, Pages: 44–51, Tiina Jaakkola, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman

    Version of Record online : 7 JUL 2006, DOI: 10.1111/j.1742-7843.2006.pto_437.x

  15. Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms

    Clinical Pharmacology & Therapeutics

    Volume 76, Issue 2, August 2004, Pages: 119–127, Elena García-Martín, Carmen Martínez, Beatriz Tabarés, Jesús Frías and José A. G. Agúndez

    Version of Record online : 15 AUG 2004, DOI: 10.1016/j.clpt.2004.04.006

  16. Influence of CYP2C8*2 on the Pharmacokinetics of Pioglitazone in Healthy African-American Volunteers

    Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

    Volume 33, Issue 9, September 2013, Pages: 1000–1007, Christina L. Aquilante, Michael F. Wempe, Samantha H. Spencer, Lisa A. Kosmiski, Julie A. Predhomme and Maha S. Sidhom

    Version of Record online : 26 MAY 2013, DOI: 10.1002/phar.1292

  17. Genetic polymorphism of CYP2C8 in three Malaysian ethnics: CYP2C8*2 and CYP2C8*3 are found in Malaysian Indians

    Journal of Clinical Pharmacy and Therapeutics

    Volume 30, Issue 5, October 2005, Pages: 487–490, Y. D. Muthiah, W. L. Lee, L. K. Teh, C. E. Ong and R. Ismail

    Version of Record online : 5 SEP 2005, DOI: 10.1111/j.1365-2710.2005.00653.x

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    The Role of Human CYP2C8 and CYP2C9 Variants in Pioglitazone Metabolism In Vitro

    Basic & Clinical Pharmacology & Toxicology

    Volume 105, Issue 6, December 2009, Pages: 374–379, Eugen Muschler, Jawahar Lal, Alexander Jetter, Anke Rattay, Ulrich Zanger, Gregor Zadoyan, Uwe Fuhr and Julia Kirchheiner

    Version of Record online : 15 JUL 2009, DOI: 10.1111/j.1742-7843.2009.00457.x

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    Metabolism of Repaglinide by CYP2C8 and CYP3A4 in vitro: Effect of Fibrates and Rifampicin

    Basic & Clinical Pharmacology & Toxicology

    Volume 97, Issue 4, October 2005, Pages: 249–256, Lauri I. Kajosaari, Jouko Laitila, Pertti J. Neuvonen and Janne T. Backman

    Version of Record online : 20 SEP 2005, DOI: 10.1111/j.1742-7843.2005.pto_157.x

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    Influence of CYP2C8*13 and CYP2C8*14 Alleles on Amiodarone N-Deethylation

    Basic & Clinical Pharmacology & Toxicology

    Volume 108, Issue 5, May 2011, Pages: 359–362, Nobumitsu Hanioka, Kimiaki Matsumoto, Yoshiro Saito and Shizuo Narimatsu

    Version of Record online : 31 JAN 2011, DOI: 10.1111/j.1742-7843.2010.00669.x