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There are 5758 results for: content related to: Bioavailability of bioactive food compounds: a challenging journey to bioefficacy

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    Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics – results from single oral dose studies in healthy volunteers

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1240–1254, S. Aubrey Stoch, Stefan Zajic, Julie A. Stone, Deborah L. Miller, Lucas van Bortel, Kenneth C. Lasseter, Barnali Pramanik, Caroline Cilissen, Qi Liu, Lida Liu, Boyd B. Scott, Deborah Panebianco, Yu Ding, Keith Gottesdiener and John A. Wagner

    Article first published online : 8 APR 2013, DOI: 10.1111/j.1365-2125.2012.04471.x

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    Improving clinical outcomes for naltrexone as a management of problem alcohol use

    British Journal of Clinical Pharmacology

    Volume 76, Issue 5, November 2013, Pages: 632–641, Gary K. Hulse

    Article first published online : 21 OCT 2013, DOI: 10.1111/j.1365-2125.2012.04452.x

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    Dose titration of BAF312 attenuates the initial heart rate reducing effect in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 75, Issue 3, March 2013, Pages: 831–841, Eric Legangneux, Anne Gardin and Donald Johns

    Article first published online : 5 FEB 2013, DOI: 10.1111/j.1365-2125.2012.04400.x

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    A pharmacologic perspective on newly emerging T-cell manipulation technologies

    British Journal of Clinical Pharmacology

    Volume 76, Issue 2, August 2013, Pages: 173–187, Dominic Smethurst

    Article first published online : 23 JUL 2013, DOI: 10.1111/j.1365-2125.2012.04475.x

  5. You have full text access to this OnlineOpen article
    Exenatide at therapeutic and supratherapeutic concentrations does not prolong the QTc interval in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 75, Issue 4, April 2013, Pages: 979–989, Börje Darpö, Sager Philip, Leigh MacConell, Brenda Cirincione, Malcolm Mitchell, Jenny Han, Wenying Huang, Jaret Malloy, Christine Schulteis, Larry Shen and Lisa Porter

    Article first published online : 15 MAR 2013, DOI: 10.1111/j.1365-2125.2012.04416.x

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    Clinical pharmacological properties of mipomersen (Kynamro), a second generation antisense inhibitor of apolipoprotein B

    British Journal of Clinical Pharmacology

    Volume 76, Issue 2, August 2013, Pages: 269–276, Stanley T. Crooke and Richard S. Geary

    Article first published online : 23 JUL 2013, DOI: 10.1111/j.1365-2125.2012.04469.x

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    Interactions between exercise and nutrition to prevent muscle waste during ageing

    British Journal of Clinical Pharmacology

    Volume 75, Issue 3, March 2013, Pages: 708–715, Leigh Breen and Stuart M. Phillips

    Article first published online : 5 FEB 2013, DOI: 10.1111/j.1365-2125.2012.04456.x

  8. Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 78, Issue 5, November 2014, Pages: 1122–1134, Sreeneeranj Kasichayanula, David W. Boulton, Wen-Lin Luo, A. David Rodrigues, Zheng Yang, Angela Goodenough, Michelle Lee, Mohammed Jemal and Frank LaCreta

    Article first published online : 20 OCT 2014, DOI: 10.1111/bcp.12425

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    Prescribing pattern of glucose lowering drugs in the United Kingdom in the last decade: a focus on the effects of safety warnings about rosiglitazone

    British Journal of Clinical Pharmacology

    Volume 75, Issue 3, March 2013, Pages: 861–868, Ingrid Leal, Silvana A. Romio, Martijn Schuemie, Alessandro Oteri, Miriam Sturkenboom and Gianluca Trifirò

    Article first published online : 5 FEB 2013, DOI: 10.1111/j.1365-2125.2012.04401.x

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    Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges

    British Journal of Clinical Pharmacology

    Volume 79, Issue 1, January 2015, Pages: 97–107, Kashyap Patel, Julie A. Simpson, Kevin T. Batty, Sophie Zaloumis and Carl M. Kirkpatrick

    Article first published online : 19 DEC 2014, DOI: 10.1111/bcp.12288

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    Oral bioavailability of dabigatran etexilate (Pradaxa®) after co-medication with verapamil in healthy subjects

    British Journal of Clinical Pharmacology

    Volume 75, Issue 4, April 2013, Pages: 1053–1062, Sebastian Härtter, Regina Sennewald, Gerhard Nehmiz and Paul Reilly

    Article first published online : 15 MAR 2013, DOI: 10.1111/j.1365-2125.2012.04453.x

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    Cell Damage Following Carbon Monoxide Releasing Molecule Exposure: Implications for Therapeutic Applications

    Basic & Clinical Pharmacology & Toxicology

    Volume 111, Issue 1, July 2012, Pages: 31–41, Ian C. Winburn, Kishan Gunatunga, Robert D. McKernan, Robert J. Walker, Ivan A. Sammut and Joanne C. Harrison

    Article first published online : 23 FEB 2012, DOI: 10.1111/j.1742-7843.2012.00856.x

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    Pharmacokinetics and central nervous system effects of the novel dual NK1/NK3 receptor antagonist GSK1144814 in alcohol-intoxicated volunteers

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1328–1339, Erik T. te Beek, Justin L. Hay, Jonathan N. Bullman, Clare Burgess, Kimberly J. Nahon, Erica S. Klaassen, Frank A. Gray and Joop M. A. van Gerven

    Article first published online : 8 APR 2013, DOI: 10.1111/bcp.12004

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    Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy men

    British Journal of Clinical Pharmacology

    Volume 75, Issue 6, June 2013, Pages: 1455–1467, Marieke Liem-Moolenaar, Pierre Peeters, Ingrid M. C. Kamerling, Chris Hogg, Graham Holder, Huub Jan Kleijn, Edwin Spaans, Joanna Udo De Haes, Marieke L. de Kam, Kari L. Franson, Adam F. Cohen and Joop M. A. van Gerven

    Article first published online : 20 MAY 2013, DOI: 10.1111/bcp.12015

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    Clinical pharmacology of AMG 181, a gut-specific human anti-α4β7 monoclonal antibody, for treating inflammatory bowel diseases

    British Journal of Clinical Pharmacology

    Volume 78, Issue 6, December 2014, Pages: 1315–1333, Wei-Jian Pan, Kathleen Köck, William A. Rees, Barbara A. Sullivan, Christine M. Evangelista, Mark Yen, Jane M. Andrews, Graham L. Radford-Smith, Peter J. Prince, Kaz O. Reynhardt, David R. Doherty, Sonal K. Patel, Christine D. Krill, Kefei Zhou, Jing Shen, Lynn E. Smith, Jason M. Gow, Jonathan Lee, Anthony M. Treacy, Zhigang Yu, Virginia M. Platt and Dominic C. Borie

    Article first published online : 20 NOV 2014, DOI: 10.1111/bcp.12418

  16. The evolution of Reference Drug Lists and Clinical Practice Guidelines in the public health system of a middle-income country

    British Journal of Clinical Pharmacology

    Volume 78, Issue 2, August 2014, Pages: 410–421, Israel Rico-Alba and Albert Figueras

    Article first published online : 21 JUL 2014, DOI: 10.1111/bcp.12337

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    Safety, tolerability and pharmacokinetics of a human anti-interleukin-13 monoclonal antibody (CNTO 5825) in an ascending single-dose first-in-human study

    British Journal of Clinical Pharmacology

    Volume 75, Issue 5, May 2013, Pages: 1289–1298, Bart van Hartingsveldt, Ivo P. Nnane, Esther Bouman-Thio, Matthew J. Loza, Alexa Piantone, Hugh M. Davis and Kevin J. Petty

    Article first published online : 8 APR 2013, DOI: 10.1111/j.1365-2125.2012.04477.x

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    Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway

    British Journal of Clinical Pharmacology

    Volume 75, Issue 3, March 2013, Pages: 677–696, Satnam Lidder and Andrew J. Webb

    Article first published online : 5 FEB 2013, DOI: 10.1111/j.1365-2125.2012.04420.x

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    Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials

    British Journal of Clinical Pharmacology

    Volume 76, Issue 5, November 2013, Pages: 649–667, Pritesh N. Bodalia, Anthony M. Grosso, Reecha Sofat, Raymond J. MacAllister, Liam Smeeth, Soraya Dhillon, Juan-Pablo Casas, David Wonderling and Aroon D. Hingorani

    Article first published online : 21 OCT 2013, DOI: 10.1111/bcp.12083

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    Influence of gestational diabetes on the stereoselective pharmacokinetics and placental distribution of metoprolol and its metabolites in parturients

    British Journal of Clinical Pharmacology

    Volume 79, Issue 4, April 2015, Pages: 605–616, Natalícia de Jesus Antunes, Ricardo Carvalho Cavalli, Maria Paula Marques, Elaine Christine Dantas Moisés and Vera Lucia Lanchote

    Article first published online : 23 MAR 2015, DOI: 10.1111/bcp.12523