Search Results

There are 16752 results for: content related to: MS-1020 is a novel small molecule that selectively inhibits JAK3 activity

  1. Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs

    Immunological Reviews

    Volume 203, Issue 1, February 2005, Pages: 127–142, Marko Pesu, Fabio Candotti, Matthew Husa, Sigrun R. Hofmann, Luigi D. Notarangelo and John J. O'Shea

    Version of Record online : 17 JAN 2005, DOI: 10.1111/j.0105-2896.2005.00220.x

  2. You have free access to this content
    Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3–receptor interaction domain

    The EMBO Journal

    Volume 18, Issue 6, March 15, 1999, Pages: 1549–1558, Nicholas A. Cacalano, Thi-Sau Migone, Fernando Bazan, Eric P. Hanson, Min Chen, Fabio Candotti, John J. O'Shea and James A. Johnston

    Version of Record online : 15 MAR 1999, DOI: 10.1093/emboj/18.6.1549

  3. You have free access to this content
    Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndrome

    British Journal of Haematology

    Volume 141, Issue 5, June 2008, Pages: 681–688, Tomohiko Sato, Tsutomu Toki, Rika Kanezaki, Gang Xu, Kiminori Terui, Hirokazu Kanegane, Masayoshi Miura, Souichi Adachi, Masahiro Migita, Shingo Morinaga, Takahide Nakano, Mikiya Endo, Seiji Kojima, Hitoshi Kiyoi, Hiroyuki Mano and Etsuro Ito

    Version of Record online : 7 APR 2008, DOI: 10.1111/j.1365-2141.2008.07081.x

  4. You have free access to this content
    Inhibition of the signalling kinase JAK3 alleviates inflammation in monoarthritic rats

    British Journal of Pharmacology

    Volume 164, Issue 1, September 2011, Pages: 106–118, Byung-Hak Kim, Myunghwan Kim, Chang-Hong Yin, Jun-Goo Jee, Claudio Sandoval, Hyejung Lee, Erika A Bach, Dae-Hyun Hahm and Gyeong-Hun Baeg

    Version of Record online : 5 AUG 2011, DOI: 10.1111/j.1476-5381.2011.01353.x

  5. You have free access to this content
    Janus kinase 3-deficient T lymphocytes have an intrinsic defect in CCR7-mediated homing to peripheral lymphoid organs

    Immunology

    Volume 122, Issue 2, October 2007, Pages: 247–260, Eduardo A. García-Zepeda, Ileana Licona-Limón, M. Fernanda Jiménez-Sólomon and Gloria Soldevila

    Version of Record online : 22 MAY 2007, DOI: 10.1111/j.1365-2567.2007.02634.x

  6. Recurrent mutation of JAK3 in T-cell prolymphocytic leukemia

    Genes, Chromosomes and Cancer

    Volume 53, Issue 4, April 2014, Pages: 309–316, Anke K. Bergmann, Sina Schneppenheim, Marc Seifert, Matthew J. Betts, Andrea Haake, Cristina Lopez, Eva Maria Murga Penas, Inga Vater, Sandrine Jayne, Martin J.S. Dyer, Martin Schrappe, Ulrich Dührsen, Ole Ammerpohl, Robert B. Russell, Ralf Küppers, Jan Dürig and Reiner Siebert

    Version of Record online : 21 JAN 2014, DOI: 10.1002/gcc.22141

  7. You have free access to this content
    LIF-dependent JAK3 activation is not essential for retinal degeneration

    Journal of Neurochemistry

    Volume 113, Issue 5, June 2010, Pages: 1210–1220, Christina Lange, Markus Thiersch, Marijana Samardzija, Sandra Bürgi, Sandrine Joly and Christian Grimm

    Version of Record online : 14 MAR 2010, DOI: 10.1111/j.1471-4159.2010.06686.x

  8. You have free access to this content
    IL-8-induced neutrophil chemotaxis is mediated by Janus kinase 3 (JAK3)

    FEBS Letters

    Volume 585, Issue 1, January 03, 2011, Pages: 159–166, Karen M. Henkels, Kathleen Frondorf, M. Elba Gonzalez-Mejia, Andrea L. Doseff and Julian Gomez-Cambronero

    Version of Record online : 21 NOV 2010, DOI: 10.1016/j.febslet.2010.11.031

  9. Janus kinases in immune cell signaling

    Immunological Reviews

    Volume 228, Issue 1, March 2009, Pages: 273–287, Kamran Ghoreschi, Arian Laurence and John J. O’Shea

    Version of Record online : 6 MAR 2009, DOI: 10.1111/j.1600-065X.2008.00754.x

  10. You have free access to this content
    Prevention of CD40-Triggered Dendritic Cell Maturation and Induction of T-Cell Hyporeactivity by Targeting of Janus Kinase 3

    American Journal of Transplantation

    Volume 3, Issue 11, November 2003, Pages: 1341–1349, Marcus D. Säemann, Christos Diakos, Peter Kelemen, Ernst Kriehuber, Maximilian Zeyda, Georg A. Böhmig, Walter H. Hörl, Thomas Baumruker and Gerhard J. Zlabinger

    Version of Record online : 28 OCT 2003, DOI: 10.1046/j.1600-6143.2003.00225.x

  11. Activated Janus Kinase 3 expression not by activating mutations identified in Natural Killer/T-cell lymphoma

    Pathology International

    Volume 64, Issue 6, June 2014, Pages: 263–266, Ying Guo, Fumiko Arakawa, Hiroaki Miyoshi, Daisuke Niino, Riko Kawano and Koichi Ohshima

    Version of Record online : 26 JUN 2014, DOI: 10.1111/pin.12166

  12. You have free access to this content
    Human lung myofibroblasts as effectors of the inflammatory process: the common receptor γ  chain is induced by Th2 cytokines, and CD40 ligand is induced by lipopolysaccharide, thrombin and TNF-α 

    European Journal of Immunology

    Volume 32, Issue 9, September 2002, Pages: 2437–2449, Christelle Doucet, Julien Giron-Michel, Giorgio Walter Canonica and Bruno Azzarone

    Version of Record online : 12 AUG 2002, DOI: 10.1002/1521-4141(200209)32:9<2437::AID-IMMU2437>3.0.CO;2-N

  13. You have full text access to this Open Access content
    Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinases

    Journal of Cellular and Molecular Medicine

    Volume 14, Issue 3, March 2010, Pages: 504–527, Claude Haan, Iris Behrmann and Serge Haan

    Version of Record online : 28 JAN 2010, DOI: 10.1111/j.1582-4934.2010.01018.x

  14. You have free access to this content
    Latent membrane protein 1 of Epstein–Barr virus interacts with JAK3 and activates STAT proteins

    The EMBO Journal

    Volume 18, Issue 11, June 1, 1999, Pages: 3064–3073, Olivier Gires, Franz Kohlhuber, Ellen Kilger, Matthias Baumann, Arnd Kieser, Christian Kaiser, Reinhard Zeidler, Beatrix Scheffer, Marius Ueffing and Wolfgang Hammerschmidt

    Version of Record online : 1 JUN 1999, DOI: 10.1093/emboj/18.11.3064

  15. You have free access to this content
    Differential Regulation of Proliferation and Differentiation in Neural Precursor Cells by the Jak Pathway

    STEM CELLS

    Volume 28, Issue 10, October 2010, Pages: 1816–1828, Yun Hee Kim, Jee-In Chung, Hyun Goo Woo, Yi-Sook Jung, Soo Hwan Lee, Chang-Hyun Moon, Haeyoung Suh-Kim and Eun Joo Baik

    Version of Record online : 26 OCT 2010, DOI: 10.1002/stem.511

  16. You have free access to this content
    Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner

    British Journal of Pharmacology

    Volume 145, Issue 6, July 2005, Pages: 818–828, Watchara Linwong, Noriyasu Hirasawa, Suzue Aoyama, Hirofumi Hamada, Takashi Saito and Kazuo Ohuchi

    Version of Record online : 29 JAN 2009, DOI: 10.1038/sj.bjp.0706240

  17. You have free access to this content
    A region encompassing the FERM domain of Jak1 is necessary for binding to the cytokine receptor gp130

    FEBS Letters

    Volume 505, Issue 1, September 07, 2001, Pages: 87–91, Catharien M.U. Hilkens, Hayaatun Is'harc, Björn F. Lillemeier, Birgit Strobl, Paul A. Bates, Iris Behrmann and Ian M. Kerr

    Version of Record online : 20 AUG 2001, DOI: 10.1016/S0014-5793(01)02783-1

  18. You have free access to this content
    Rapid protein-based assays for the diagnosis of TB+ severe combined immunodeficiency

    British Journal of Haematology

    Volume 112, Issue 3, March 2001, Pages: 671–676, Kimberly C. Gilmour, Treena Cranston, Sam Loughlin, Jackie Gwyther, Tracy Lester, Teresa Espanol, Manuel Hernandez, Gianfranco Savoldi, E. Graham Davies, Mario Abinun, Christine Kinnon, Alison Jones and Hubert B. Gaspar

    Version of Record online : 20 DEC 2001, DOI: 10.1046/j.1365-2141.2001.02578.x

  19. Therapeutic targeting of Janus kinases

    Immunological Reviews

    Volume 223, Issue 1, June 2008, Pages: 132–142, Marko Pesu, Arian Laurence, Nandini Kishore, Samuel H. Zwillich, Gary Chan and John J. O'Shea

    Version of Record online : 8 JUL 2008, DOI: 10.1111/j.1600-065X.2008.00644.x

  20. A novel JAK3 mutation in a Japanese patient with severe combined immunodeficiency

    Pediatrics International

    Volume 47, Issue 5, October 2005, Pages: 575–578, Toru Uchiyama, Satoru Kumaki, Mitsuhiro Fujiwara, Yoshinobu Nishida, Ikuko Hakozaki, Kaori Imai, Wei Du, Miyako Yoshinari, Yoji Sasahara and Shigeru Tsuchiya

    Version of Record online : 28 SEP 2005, DOI: 10.1111/j.1442-200x.2005.02103.x